104 items (Spizellomyces punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SPPG_02087	TPR_REGION domain-containing protein. (308 aa)
	SPPG_08982	Peptidase_S24 domain-containing protein. (176 aa)
	SPPG_00902	zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family. (107 aa)
	SPPG_02205	Pex14_N domain-containing protein. (335 aa)
	SPPG_02184	Uncharacterized protein; Belongs to the peptidase M16 family. (487 aa)
	SPPG_02281	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family. (368 aa)
	SPPG_02295	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (412 aa)
	SPPG_01097	POTRA domain-containing protein. (481 aa)
	SPPG_02369	Uncharacterized protein. (319 aa)
	MDM10	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...] (350 aa)
	SPPG_02288	Uncharacterized protein. (797 aa)
	SPPG_02370	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (363 aa)
	SPPG_01050	Uncharacterized protein. (1264 aa)
	SPPG_01234	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (356 aa)
	SPPG_08941	PX domain-containing protein. (575 aa)
	SPPG_01095	Protein transporter Sec61 subunit alpha isoform 2. (472 aa)
	SPPG_01544	Uncharacterized protein. (567 aa)
	SPPG_00255	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (242 aa)
	SPPG_00098	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (309 aa)
	SPPG_00411	Uncharacterized protein. (330 aa)
	SPPG_00265	zf-Tim10_DDP domain-containing protein. (86 aa)
	SPPG_00716	J domain-containing protein. (664 aa)
	SPPG_00505	Uncharacterized protein. (158 aa)
	SPPG_00547	Uncharacterized protein. (357 aa)
	SPPG_08883	Uncharacterized protein. (832 aa)
	SPPG_00777	Uncharacterized protein; Belongs to the GroES chaperonin family. (103 aa)
	SPPG_00807	VPS37 C-terminal domain-containing protein. (321 aa)
	SPPG_00857	Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (641 aa)
	SPPG_00813	Uncharacterized protein. (117 aa)
	SPPG_02791	Uncharacterized protein. (111 aa)
	SPPG_03697	Uncharacterized protein. (199 aa)
	SPPG_03570	TPR_REGION domain-containing protein. (569 aa)
	SPPG_03370	SH3 domain-containing protein. (437 aa)
	SPPG_03192	SET domain-containing protein. (576 aa)
	SPPG_03274	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (398 aa)
	MMM1	Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] (346 aa)
	SPPG_03597	Uncharacterized protein. (1287 aa)
	SPPG_04246	UBIQUITIN_CONJUGAT_2 domain-containing protein. (136 aa)
	SPPG_04221	Uncharacterized protein. (150 aa)
	SPPG_04211	Uncharacterized protein. (162 aa)
	SPPG_04205	TPR_REGION domain-containing protein. (724 aa)
	SPPG_04282	Uncharacterized protein. (238 aa)
	SPPG_03320	Uncharacterized protein. (1154 aa)
	SPPG_04202	DNL-type domain-containing protein. (175 aa)
	SPPG_09176	Uncharacterized protein. (414 aa)
	SPPG_04867	Uncharacterized protein. (391 aa)
	SPPG_04162	Uncharacterized protein; Belongs to the actin family. (393 aa)
	SPPG_04806	Uncharacterized protein. (200 aa)
	SPPG_04134	Uncharacterized protein. (127 aa)
	SPPG_04775	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (525 aa)
	SPPG_04776	Uncharacterized protein. (187 aa)
	SPPG_03808	Uncharacterized protein. (186 aa)
	SPPG_09193	AN1-type domain-containing protein. (154 aa)
	SPPG_04695	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (529 aa)
	SPPG_05044	Uncharacterized protein. (294 aa)
	SPPG_04953	Sec62 family protein translocation protein. (250 aa)
	SPPG_09234	Chaperonin GroL; Belongs to the chaperonin (HSP60) family. (587 aa)
	SPPG_05933	Uncharacterized protein. (3047 aa)
	SPPG_05512	Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family. (661 aa)
	SPPG_05723	Uncharacterized protein. (200 aa)
	SPPG_06184	Uncharacterized protein. (1788 aa)
	SPPG_06108	J domain-containing protein. (98 aa)
	SPPG_09345	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (298 aa)
	SPPG_06609	Uncharacterized protein. (216 aa)
	SPPG_06897	Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
	SPPG_07143	VPS15 protein kinase. (1577 aa)
	MED17	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (630 aa)
	SPPG_07424	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (419 aa)
	SPPG_07095	Uncharacterized protein. (224 aa)
	SPPG_07243	Mitochondrial inner membrane protease subunit. (203 aa)
	SPPG_07355	Uncharacterized protein. (508 aa)
	SPPG_07541	RING-type domain-containing protein. (318 aa)
	SPPG_07442	Pex14_N domain-containing protein. (424 aa)
	SPPG_07542	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (495 aa)
	SPPG_07533	ATP-dependent Clp protease, ATP-binding subunit ClpX. (516 aa)
	SPPG_07709	Uncharacterized protein. (411 aa)
	SPPG_07642	Uncharacterized protein. (595 aa)
	SPPG_08161	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (771 aa)
	SPPG_07881	Uncharacterized protein. (189 aa)
	SPPG_08090	WD_REPEATS_REGION domain-containing protein. (320 aa)
	SPPG_08076	AAA domain-containing protein; Belongs to the AAA ATPase family. (356 aa)
	SPPG_08450	Sulfhydryl oxidase. (192 aa)
	SPPG_08526	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1067 aa)
	SPPG_08527	Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (222 aa)
	SPPG_08416	SRP9-21 domain-containing protein. (118 aa)
	SPPG_01973	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (807 aa)
	SPPG_02253	Uncharacterized protein. (250 aa)
	SPPG_09002	Signal peptidase subunit 3. (181 aa)
	SPPG_01888	CHY-type domain-containing protein. (115 aa)
	SPPG_01873	Uncharacterized protein. (626 aa)
	SPPG_02127	ADP-ribosylation factor-like protein 1, variant; Belongs to the small GTPase superfamily. Arf family. (182 aa)
	SPPG_02973	Uncharacterized protein. (203 aa)
	SPPG_02954	Uncharacterized protein. (1104 aa)
	SPPG_02051	Uncharacterized protein. (572 aa)
	SPPG_03030	Protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic. (70 aa)
	SPPG_03015	J domain-containing protein. (545 aa)
	SPPG_03000	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (235 aa)
	SPPG_02794	TPR_REGION domain-containing protein. (219 aa)
	SPPG_01843	Tim44 domain-containing protein. (424 aa)
	SPPG_02851	Uncharacterized protein. (245 aa)
	MDM12	Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...] (459 aa)
	SPPG_02481	SRP54 domain-containing protein. (616 aa)
	SPPG_02487	Uncharacterized protein. (105 aa)
	SPPG_03581	RING-type domain-containing protein. (364 aa)

Your Current Organism:

Spizellomyces punctatus

NCBI taxonomy Id: 645134
Other names: S. punctatus DAOM BR117, Spizellomyces punctatus DAOM BR117

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MDM10	MDM12	A0A0L0HQL2	A0A0L0HME0	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...]	0.968
MDM10	MMM1	A0A0L0HQL2	A0A0L0HKB1	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...]	0.979
MDM10	SPPG_00098	A0A0L0HQL2	A0A0L0HU14	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.439
MDM10	SPPG_00265	A0A0L0HQL2	A0A0L0HUG6	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	zf-Tim10_DDP domain-containing protein.	0.402
MDM10	SPPG_00505	A0A0L0HQL2	A0A0L0HUK6	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	Uncharacterized protein.	0.647
MDM10	SPPG_00902	A0A0L0HQL2	A0A0L0HPS2	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family.	0.562
MDM10	SPPG_01097	A0A0L0HQL2	A0A0L0HQG0	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	POTRA domain-containing protein.	0.950
MDM10	SPPG_01873	A0A0L0HQL2	A0A0L0HNX2	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	Uncharacterized protein.	0.482
MDM10	SPPG_02369	A0A0L0HQL2	A0A0L0HQI2	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	Uncharacterized protein.	0.499
MDM10	SPPG_03192	A0A0L0HQL2	A0A0L0HKF8	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	SET domain-containing protein.	0.410
MDM10	SPPG_04867	A0A0L0HQL2	A0A0L0HI97	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	Uncharacterized protein.	0.804
MDM10	SPPG_05933	A0A0L0HQL2	A0A0L0HDY5	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	Uncharacterized protein.	0.535
MDM12	MDM10	A0A0L0HME0	A0A0L0HQL2	Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...]	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	0.968
MDM12	MMM1	A0A0L0HME0	A0A0L0HKB1	Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...]	Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...]	0.976
MDM12	SPPG_02127	A0A0L0HME0	A0A0L0HNT7	Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...]	ADP-ribosylation factor-like protein 1, variant; Belongs to the small GTPase superfamily. Arf family.	0.441
MED17	SPPG_00716	A0A0L0H9P3	A0A0L0HUK3	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	J domain-containing protein.	0.871
MED17	SPPG_01095	A0A0L0H9P3	A0A0L0HRZ1	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Protein transporter Sec61 subunit alpha isoform 2.	0.804
MED17	SPPG_03030	A0A0L0H9P3	A0A0L0HNF9	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic.	0.860
MED17	SPPG_03808	A0A0L0H9P3	A0A0L0HGV0	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.793
MED17	SPPG_04953	A0A0L0H9P3	A0A0L0HF73	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Sec62 family protein translocation protein.	0.870