152 items (Spizellomyces punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SPPG_03506	Uncharacterized protein. (582 aa)
	SPPG_08517	JmjC domain-containing protein. (396 aa)
	SPPG_08703	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (626 aa)
	SPPG_08304	Hist_deacetyl domain-containing protein. (384 aa)
	SPPG_08047	CBFD_NFYB_HMF domain-containing protein. (124 aa)
	SPPG_08084	Uncharacterized protein. (1692 aa)
	SPPG_08089	Hist_deacetyl domain-containing protein. (392 aa)
	SPPG_08370	Prefoldin, alpha subunit. (187 aa)
	SPPG_08281	Uncharacterized protein. (893 aa)
	SPPG_08026	Uncharacterized protein. (244 aa)
	SPPG_08638	Bromo domain-containing protein. (1226 aa)
	SPPG_08400	Uncharacterized protein. (506 aa)
	SPPG_07816	Uncharacterized protein. (847 aa)
	SPPG_07919	RING-type domain-containing protein. (703 aa)
	SPPG_07899	Uncharacterized protein. (842 aa)
	SPPG_07317	JmjC domain-containing protein. (400 aa)
	SPPG_07472	TAFII28 domain-containing protein. (190 aa)
	SPPG_07796	Uncharacterized protein. (970 aa)
	SPPG_07298	Uncharacterized protein. (300 aa)
	SPPG_06969	NDT80 domain-containing protein. (591 aa)
	MED18	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (270 aa)
	SPPG_06549	Zn(2)-C6 fungal-type domain-containing protein. (470 aa)
	SPPG_07281	ANK_REP_REGION domain-containing protein. (508 aa)
	SPPG_07290	Uncharacterized protein. (322 aa)
	SPPG_07078	Uncharacterized protein. (1384 aa)
	SPPG_06898	BZIP domain-containing protein. (349 aa)
	SPPG_07325	PHD-type domain-containing protein. (790 aa)
	SPPG_06806	GATA-type domain-containing protein. (387 aa)
	SPPG_06083	ANK_REP_REGION domain-containing protein. (1187 aa)
	SPPG_06988	BTP domain-containing protein. (328 aa)
	SPPG_07036	Uncharacterized protein. (998 aa)
	SPPG_06202	Uncharacterized protein. (238 aa)
	SPPG_06260	Uncharacterized protein. (479 aa)
	SPPG_06646	Chromatin modification-related protein. (324 aa)
	SPPG_06894	Uncharacterized protein. (1023 aa)
	SPPG_06598	Uncharacterized protein. (522 aa)
	SPPG_06596	3'-5' exonuclease domain-containing protein. (521 aa)
	SPPG_06547	Uncharacterized protein. (538 aa)
	SPPG_06562	Uncharacterized protein; Belongs to the MT-A70-like family. (357 aa)
	SPPG_06099	BHLH domain-containing protein. (475 aa)
	SPPG_06208	MADS-box domain-containing protein. (387 aa)
	SPPG_05835	Uncharacterized protein. (157 aa)
	SPPG_06287	Uncharacterized protein. (204 aa)
	SPPG_06295	Uncharacterized protein. (1033 aa)
	SPPG_05775	BHLH domain-containing protein. (564 aa)
	SPPG_05420	Uncharacterized protein. (311 aa)
	SPPG_05492	GATA-type domain-containing protein. (576 aa)
	SPPG_05523	WD_REPEATS_REGION domain-containing protein. (495 aa)
	SPPG_05689	Uncharacterized protein. (1830 aa)
	SPPG_05355	Eukaryotic translation initiation factor 2 subunit gamma. (452 aa)
	SPPG_04345	Zn(2)-C6 fungal-type domain-containing protein. (506 aa)
	SPPG_05010	Zn(2)-C6 fungal-type domain-containing protein. (410 aa)
	SPPG_05269	Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation. (453 aa)
	SPPG_04691	Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (744 aa)
	SPPG_04342	BHLH domain-containing protein. (351 aa)
	SPPG_04779	Homeobox domain-containing protein. (449 aa)
	SPPG_05312	Histone H2A; Belongs to the histone H2A family. (136 aa)
	SPPG_04600	Uncharacterized protein. (983 aa)
	SPPG_04393	Uncharacterized protein. (646 aa)
	SPPG_04472	Nuclear transcription factor Y subunit B-3. (235 aa)
	SPPG_04681	SAGA-associated factor 11. (245 aa)
	SPPG_04510	Uncharacterized protein. (437 aa)
	SPPG_03982	CMGC/CDK/CDK7 protein kinase. (353 aa)
	SPPG_04543	Homeobox domain-containing protein. (504 aa)
	SPPG_04833	Uncharacterized protein. (498 aa)
	SPPG_04850	Uncharacterized protein. (681 aa)
	SPPG_04602	NDT80 domain-containing protein. (610 aa)
	SPPG_04028	GATA-type domain-containing protein. (417 aa)
	SPPG_04644	Fibronectin type-III domain-containing protein. (1030 aa)
	SPPG_04668	BZIP domain-containing protein. (515 aa)
	SPPG_04876	Uncharacterized protein. (1602 aa)
	SPPG_03780	Uncharacterized protein. (232 aa)
	SPPG_04737	Uncharacterized protein. (500 aa)
	SPPG_03805	Uncharacterized protein. (598 aa)
	SPPG_04848	Abhydrolase_3 domain-containing protein. (437 aa)
	SPPG_03956	Uncharacterized protein. (274 aa)
	SPPG_03966	SCA7 domain-containing protein. (604 aa)
	SPPG_03908	SCA7 domain-containing protein. (293 aa)
	SPPG_03787	Abhydrolase_3 domain-containing protein. (455 aa)
	SPPG_03091	Myocyte-specific enhancer factor 2C. (239 aa)
	SPPG_03998	Uncharacterized protein. (294 aa)
	SPPG_03179	GATA-type domain-containing protein. (767 aa)
	SPPG_04140	Uncharacterized protein. (243 aa)
	SPPG_04031	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (117 aa)
	SPPG_04313	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (394 aa)
	SPPG_04138	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (122 aa)
	SPPG_03077	Uncharacterized protein. (1031 aa)
	SPPG_04100	GTP-binding protein TypA/BipA. (577 aa)
	SPPG_04118	PHD-type domain-containing protein. (569 aa)
	SUS1	Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...] (97 aa)
	SPPG_03514	Plus3 domain-containing protein. (500 aa)
	SPPG_03137	Zn(2)-C6 fungal-type domain-containing protein. (388 aa)
	SPPG_03165	Uncharacterized protein. (449 aa)
	SPPG_03321	Uncharacterized protein. (513 aa)
	SPPG_03127	Uncharacterized protein. (503 aa)
	SPPG_02464	CBFD_NFYB_HMF domain-containing protein. (214 aa)
	SPPG_02497	Eukaryotic translation initiation factor 5A. (159 aa)
	SPPG_03220	Uncharacterized protein. (178 aa)
	SPPG_03535	Cell differentiation protein rcd1. (341 aa)
	SPPG_09106	BZIP domain-containing protein. (407 aa)
	SPPG_03652	CBFD_NFYB_HMF domain-containing protein. (297 aa)
	SPPG_03662	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (486 aa)
	SPPG_03451	Uncharacterized protein. (360 aa)
	SPPG_02799	ABC transporter E family member 2. (602 aa)
	SPPG_03655	Uncharacterized protein. (941 aa)
	GUF1	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (692 aa)
	SPPG_09029	Uncharacterized protein. (294 aa)
	SPPG_02848	Peptidase_M50 domain-containing protein. (535 aa)
	SPPG_02883	Fork-head domain-containing protein. (519 aa)
	SPPG_01868	TMF_TATA_bd domain-containing protein. (923 aa)
	SPPG_02944	Uncharacterized protein. (577 aa)
	SPPG_02962	Uncharacterized protein. (110 aa)
	SPPG_02885	HTH APSES-type domain-containing protein. (342 aa)
	SPPG_01774	TPR_REGION domain-containing protein. (1013 aa)
	SPPG_03027	Uncharacterized protein. (373 aa)
	SPPG_02946	Uncharacterized protein. (1557 aa)
	SPPG_01844	BHLH domain-containing protein. (325 aa)
	SPPG_01923	HMG box domain-containing protein. (302 aa)
	SPPG_01833	Uncharacterized protein. (843 aa)
	SPPG_01802	SWIRM domain-containing protein. (282 aa)
	SPPG_08986	Uncharacterized protein. (821 aa)
	SPPG_02161	Smg4_UPF3 domain-containing protein. (522 aa)
	SPPG_02143	Uncharacterized protein. (491 aa)
	SPPG_02381	zf-C2HC5 domain-containing protein. (547 aa)
	SPPG_01030	BHLH domain-containing protein. (278 aa)
	SPPG_00914	Uncharacterized protein. (988 aa)
	SPPG_08931	Uncharacterized protein. (1072 aa)
	SPPG_01139	Uncharacterized protein. (498 aa)
	SPPG_01135	Uncharacterized protein; Belongs to the actin family. (723 aa)
	SPPG_01609	S4 RNA-binding domain-containing protein. (317 aa)
	SPPG_01151	Uncharacterized protein. (621 aa)
	SPPG_01276	WD_REPEATS_REGION domain-containing protein. (579 aa)
	SPPG_00029	PITH domain-containing protein. (219 aa)
	SPPG_01488	CDC73_C domain-containing protein. (423 aa)
	SPPG_00077	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3864 aa)
	SPPG_01361	HTH cro/C1-type domain-containing protein. (146 aa)
	SPPG_01401	WD_REPEATS_REGION domain-containing protein. (885 aa)
	SPPG_01617	Uncharacterized protein. (1540 aa)
	SPPG_01635	Uncharacterized protein. (518 aa)
	SPPG_01683	Bromo domain-containing protein. (1286 aa)
	SPPG_01570	HMG box domain-containing protein. (447 aa)
	SPPG_00129	C2H2-type domain-containing protein. (635 aa)
	SPPG_00407	YTH domain-containing protein. (1144 aa)
	SPPG_00205	Uncharacterized protein. (262 aa)
	SPPG_00631	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (463 aa)
	SPPG_00300	PC4 domain-containing protein. (143 aa)
	SPPG_00510	RPOL4c domain-containing protein. (180 aa)
	SPPG_08841	Eukaryotic translation initiation factor 5A. (159 aa)
	SPPG_08859	Uncharacterized protein. (609 aa)
	SPPG_00550	SGF29 C-terminal domain-containing protein. (281 aa)
	SPPG_00695	Uncharacterized protein. (924 aa)
	SPPG_00779	CBFD_NFYB_HMF domain-containing protein. (156 aa)

Your Current Organism:

Spizellomyces punctatus

NCBI taxonomy Id: 645134
Other names: S. punctatus DAOM BR117, Spizellomyces punctatus DAOM BR117

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GUF1	SPPG_01609	A0A0L0HMB8	A0A0L0HS43	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	S4 RNA-binding domain-containing protein.	0.691
GUF1	SPPG_04737	A0A0L0HMB8	A0A0L0HHW8	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	Uncharacterized protein.	0.451
MED18	SPPG_00510	A0A0L0H950	A0A0L0HUM9	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	RPOL4c domain-containing protein.	0.909
MED18	SPPG_01151	A0A0L0H950	A0A0L0HS56	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.727
MED18	SPPG_03220	A0A0L0H950	A0A0L0HKP8	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.917
MED18	SPPG_03655	A0A0L0H950	A0A0L0HLT0	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.938
MED18	SPPG_03780	A0A0L0H950	A0A0L0HHU5	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.797
MED18	SPPG_03982	A0A0L0H950	A0A0L0HHD1	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	CMGC/CDK/CDK7 protein kinase.	0.537
MED18	SPPG_05312	A0A0L0H950	A0A0L0HGA4	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Histone H2A; Belongs to the histone H2A family.	0.554
MED18	SPPG_06988	A0A0L0H950	A0A0L0HA22	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	BTP domain-containing protein.	0.623
MED18	SPPG_07298	A0A0L0H950	A0A0L0H8Q3	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.538
MED18	SPPG_07472	A0A0L0H950	A0A0L0H830	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	TAFII28 domain-containing protein.	0.656
SPPG_00077	SPPG_00695	A0A0L0HSK6	A0A0L0HVV8	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.614
SPPG_00077	SPPG_02161	A0A0L0HSK6	A0A0L0HPU1	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Smg4_UPF3 domain-containing protein.	0.446
SPPG_00077	SPPG_03662	A0A0L0HSK6	A0A0L0HLD7	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.607
SPPG_00077	SPPG_04313	A0A0L0HSK6	A0A0L0HJD4	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	0.590
SPPG_00077	SPPG_06596	A0A0L0HSK6	A0A0L0HBG0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	3'-5' exonuclease domain-containing protein.	0.511
SPPG_00077	SPPG_07078	A0A0L0HSK6	A0A0L0H9N6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.712
SPPG_00077	SPPG_07816	A0A0L0HSK6	A0A0L0H667	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.500
SPPG_00077	SPPG_08703	A0A0L0HSK6	A0A0L0H424	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.607