STRINGSTRING
SPPG_06431 SPPG_06431 SPPG_07100 SPPG_07100 SPPG_07640 SPPG_07640 SPPG_06784 SPPG_06784 SPPG_06496 SPPG_06496 SPPG_07605 SPPG_07605 SPPG_07392 SPPG_07392 SPPG_07511 SPPG_07511 SPPG_07436 SPPG_07436 SPPG_07256 SPPG_07256 SPPG_08019 SPPG_08019 SPPG_07261 SPPG_07261 SPPG_07074 SPPG_07074 SPPG_07803 SPPG_07803 SPPG_07366 SPPG_07366 SPPG_07249 SPPG_07249 SPPG_08059 SPPG_08059 SPPG_08034 SPPG_08034 SPPG_06592 SPPG_06592 SPPG_08186 SPPG_08186 SPPG_08433 SPPG_08433 SPPG_08605 SPPG_08605 SPPG_08581 SPPG_08581 SPPG_08319 SPPG_08319 SPPG_08439 SPPG_08439 SPPG_08584 SPPG_08584 SPPG_08528 SPPG_08528 SPPG_08543 SPPG_08543 SPPG_08678 SPPG_08678 SPPG_06944 SPPG_06944 SPPG_06526 SPPG_06526 SPPG_06965 SPPG_06965 SPPG_06885 SPPG_06885 SPPG_06576 SPPG_06576 SPPG_06553 SPPG_06553 SPPG_06596 SPPG_06596 SPPG_06125 SPPG_06125 SPPG_06135 SPPG_06135 SPPG_05899 SPPG_05899 SPPG_06362 SPPG_06362 SPPG_05920 SPPG_05920 SPPG_05468 SPPG_05468 SPPG_06028 SPPG_06028 SPPG_05395 SPPG_05395 SPPG_05388 SPPG_05388 SPPG_05551 SPPG_05551 SPPG_05115 SPPG_05115 SPPG_05377 SPPG_05377 SPPG_05422 SPPG_05422 SPPG_04913 SPPG_04913 SPPG_05702 SPPG_05702 SPPG_05350 SPPG_05350 SPPG_04367 SPPG_04367 SPPG_05208 SPPG_05208 SPPG_04376 SPPG_04376 SPPG_04386 SPPG_04386 SPPG_09270 SPPG_09270 SPPG_05300 SPPG_05300 SPPG_04378 SPPG_04378 SPPG_04752 SPPG_04752 SPPG_03918 SPPG_03918 SPPG_04476 SPPG_04476 SPPG_04657 SPPG_04657 SPPG_03730 SPPG_03730 SPPG_03755 SPPG_03755 SPPG_04261 SPPG_04261 SPPG_03128 SPPG_03128 SPPG_04013 SPPG_04013 SPPG_03148 SPPG_03148 SPPG_09154 SPPG_09154 SPPG_08726 SPPG_08726 SPPG_03930 SPPG_03930 SPPG_04117 SPPG_04117 SPPG_04150 SPPG_04150 SPPG_03985 SPPG_03985 SPPG_03994 SPPG_03994 SPPG_03102 SPPG_03102 SPPG_03459 SPPG_03459 SPPG_03514 SPPG_03514 SPPG_04185 SPPG_04185 SPPG_04275 SPPG_04275 SPPG_03557 SPPG_03557 SPPG_03162 SPPG_03162 SPPG_03253 SPPG_03253 SPPG_03468 SPPG_03468 SPPG_03558 SPPG_03558 SPPG_03608 SPPG_03608 SPPG_03458 SPPG_03458 SPPG_03532 SPPG_03532 SPPG_09124 SPPG_09124 SPPG_02882 SPPG_02882 SPPG_03690 SPPG_03690 SPPG_02604 SPPG_02604 SPPG_02951 SPPG_02951 SPPG_02671 SPPG_02671 SPPG_02741 SPPG_02741 SPPG_01799 SPPG_01799 SPPG_01809 SPPG_01809 SPPG_02862 SPPG_02862 SPPG_02739 SPPG_02739 SPPG_09073 SPPG_09073 SPPG_02830 SPPG_02830 SPPG_02966 SPPG_02966 SPPG_01951 SPPG_01951 SPPG_01962 SPPG_01962 SPPG_02077 SPPG_02077 SPPG_02096 SPPG_02096 SPPG_02880 SPPG_02880 SPPG_01806 SPPG_01806 SPPG_03002 SPPG_03002 SPPG_01899 SPPG_01899 SPPG_01909 SPPG_01909 SPPG_02047 SPPG_02047 SPPG_01901 SPPG_01901 SPPG_01905 SPPG_01905 SPPG_02305 SPPG_02305 USB1 USB1 SPPG_02335 SPPG_02335 PAN2 PAN2 SPPG_00981 SPPG_00981 SPPG_01277 SPPG_01277 SPPG_00910 SPPG_00910 SPPG_01063 SPPG_01063 FEN1 FEN1 SPPG_08895 SPPG_08895 SPPG_01019 SPPG_01019 SPPG_01555 SPPG_01555 SPPG_01134 SPPG_01134 SPPG_01176 SPPG_01176 SLX1 SLX1 SPPG_01236 SPPG_01236 SPPG_01506 SPPG_01506 SPPG_01507 SPPG_01507 SPPG_00306 SPPG_00306 SPPG_08818 SPPG_08818 SPPG_01623 SPPG_01623 SPPG_00041 SPPG_00041 SPPG_00267 SPPG_00267 SPPG_00126 SPPG_00126 SPPG_00125 SPPG_00125 SPPG_00164 SPPG_00164 SPPG_00387 SPPG_00387 SPPG_00422 SPPG_00422 SPPG_00723 SPPG_00723 SPPG_00305 SPPG_00305 SPPG_00746 SPPG_00746 SPPG_00780 SPPG_00780 SPPG_00449 SPPG_00449 SPPG_00513 SPPG_00513 SPPG_00728 SPPG_00728 SPPG_00606 SPPG_00606 SPPG_00619 SPPG_00619 SPPG_00795 SPPG_00795 SPPG_00833 SPPG_00833
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPPG_06431Endo/exonuclease/phosphatase domain-containing protein. (151 aa)
SPPG_07100WD_REPEATS_REGION domain-containing protein. (902 aa)
SPPG_07640Uncharacterized protein. (460 aa)
SPPG_06784Uncharacterized protein. (912 aa)
SPPG_06496Uncharacterized protein. (408 aa)
SPPG_07605Uncharacterized protein; Belongs to the argonaute family. (885 aa)
SPPG_073925'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (1092 aa)
SPPG_07511RAI1 domain-containing protein. (428 aa)
SPPG_07436Fip1 domain-containing protein. (393 aa)
SPPG_07256DNA repair protein (Rad1). (1030 aa)
SPPG_08019Endo/exonuclease/phosphatase domain-containing protein. (672 aa)
SPPG_07261Uncharacterized protein. (508 aa)
SPPG_07074DBR1 domain-containing protein. (629 aa)
SPPG_07803Endonuclease. (331 aa)
SPPG_07366XendoU domain-containing protein. (400 aa)
SPPG_07249tRNA_int_end_N2 domain-containing protein. (368 aa)
SPPG_08059WD_REPEATS_REGION domain-containing protein. (602 aa)
SPPG_08034Uncharacterized protein. (316 aa)
SPPG_06592POLAc domain-containing protein. (1188 aa)
SPPG_08186PINc domain-containing protein. (192 aa)
SPPG_08433Uncharacterized protein. (1886 aa)
SPPG_08605Uncharacterized protein. (1360 aa)
SPPG_08581Uncharacterized protein. (458 aa)
SPPG_08319Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 9. (1125 aa)
SPPG_08439PINc domain-containing protein. (1122 aa)
SPPG_08584DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (107 aa)
SPPG_08528Uncharacterized protein; Belongs to the argonaute family. (897 aa)
SPPG_08543Uncharacterized protein. (654 aa)
SPPG_08678SAP30_Sin3_bdg domain-containing protein. (121 aa)
SPPG_06944Uncharacterized protein; Belongs to the argonaute family. (894 aa)
SPPG_06526Endo/exonuclease/phosphatase domain-containing protein. (725 aa)
SPPG_06965Uncharacterized protein. (107 aa)
SPPG_06885Uncharacterized protein. (703 aa)
SPPG_06576SAP domain-containing protein. (314 aa)
SPPG_06553Uncharacterized protein. (689 aa)
SPPG_065963'-5' exonuclease domain-containing protein. (521 aa)
SPPG_06125DRMBL domain-containing protein. (739 aa)
SPPG_06135ZnF_Rad18 domain-containing protein. (535 aa)
SPPG_05899AAA domain-containing protein; Belongs to the AAA ATPase family. (428 aa)
SPPG_06362Uncharacterized protein. (749 aa)
SPPG_05920Uncharacterized protein. (172 aa)
SPPG_0546818S rRNA biogenesis protein RCL1. (364 aa)
SPPG_06028Ribonuclease Z. (395 aa)
SPPG_05395NYN domain-containing protein. (363 aa)
SPPG_05388Uncharacterized protein. (291 aa)
SPPG_05551Uncharacterized protein. (280 aa)
SPPG_05115Cleavage and polyadenylation specificity factor subunit 2. (772 aa)
SPPG_05377Uncharacterized protein. (527 aa)
SPPG_05422Exonuclease domain-containing protein. (219 aa)
SPPG_04913Uncharacterized protein; Belongs to the helicase family. Dicer subfamily. (1512 aa)
SPPG_05702RRM domain-containing protein. (347 aa)
SPPG_05350Nudix hydrolase domain-containing protein. (398 aa)
SPPG_04367Exonuclease domain-containing protein. (568 aa)
SPPG_05208IRE protein kinase. (1060 aa)
SPPG_04376Uncharacterized protein. (344 aa)
SPPG_04386UV damage endonuclease UvdE. (510 aa)
SPPG_09270Uncharacterized protein. (758 aa)
SPPG_05300Exonuclease domain-containing protein. (439 aa)
SPPG_04378XPG_I_2 domain-containing protein. (706 aa)
SPPG_04752RNB domain-containing protein. (1028 aa)
SPPG_03918HIT domain-containing protein. (779 aa)
SPPG_04476Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (302 aa)
SPPG_04657Lactamase_B domain-containing protein. (925 aa)
SPPG_03730TNase-like domain-containing protein. (255 aa)
SPPG_03755Uncharacterized protein. (1751 aa)
SPPG_04261Uncharacterized protein. (190 aa)
SPPG_03128Uncharacterized protein. (274 aa)
SPPG_04013Endo/exonuclease/phosphatase domain-containing protein. (603 aa)
SPPG_03148Uncharacterized protein. (1773 aa)
SPPG_09154Uncharacterized protein. (317 aa)
SPPG_08726Uncharacterized protein. (522 aa)
SPPG_03930Uncharacterized protein. (604 aa)
SPPG_04117Uncharacterized protein. (244 aa)
SPPG_04150DNA polymerase. (1165 aa)
SPPG_03985Uncharacterized protein. (163 aa)
SPPG_03994Uncharacterized protein; Belongs to the helicase family. Dicer subfamily. (1405 aa)
SPPG_03102Uncharacterized protein; Belongs to the RNase T2 family. (258 aa)
SPPG_03459Uncharacterized protein. (296 aa)
SPPG_03514Plus3 domain-containing protein. (500 aa)
SPPG_04185Uncharacterized protein. (261 aa)
SPPG_04275Uncharacterized protein. (260 aa)
SPPG_03557DNA repair protein rad10, variant. (352 aa)
SPPG_03162CBF domain-containing protein. (538 aa)
SPPG_03253tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] (424 aa)
SPPG_03468Uncharacterized protein. (1242 aa)
SPPG_03558tRNA intron endonuclease. (449 aa)
SPPG_03608WD_REPEATS_REGION domain-containing protein. (575 aa)
SPPG_03458S1 motif domain-containing protein. (188 aa)
SPPG_03532Uncharacterized protein. (387 aa)
SPPG_09124Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (202 aa)
SPPG_02882Protein DOM34 homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (409 aa)
SPPG_03690C3H1-type domain-containing protein. (485 aa)
SPPG_026043'-5' exonuclease domain-containing protein. (1744 aa)
SPPG_02951Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (190 aa)
SPPG_02671Uncharacterized protein. (213 aa)
SPPG_02741Uncharacterized protein. (434 aa)
SPPG_01799DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2352 aa)
SPPG_01809WD_REPEATS_REGION domain-containing protein. (880 aa)
SPPG_02862Uncharacterized protein. (291 aa)
SPPG_02739PINc domain-containing protein. (512 aa)
SPPG_09073RNase_H2-Ydr279 domain-containing protein. (233 aa)
SPPG_02830Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (174 aa)
SPPG_02966Uncharacterized protein. (225 aa)
SPPG_01951Uncharacterized protein. (698 aa)
SPPG_01962Uncharacterized protein. (303 aa)
SPPG_02077Uncharacterized protein. (1998 aa)
SPPG_02096Uncharacterized protein. (1168 aa)
SPPG_02880Bms1-type G domain-containing protein. (817 aa)
SPPG_01806DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. (1453 aa)
SPPG_03002Sen15 domain-containing protein. (131 aa)
SPPG_01899RRM domain-containing protein. (269 aa)
SPPG_01909ERCC4 domain-containing protein. (305 aa)
SPPG_02047Uncharacterized protein; Belongs to the argonaute family. (863 aa)
SPPG_01901Kri1_C domain-containing protein. (653 aa)
SPPG_01905Fcf2 domain-containing protein. (241 aa)
SPPG_02305Uncharacterized protein. (303 aa)
USB1U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA; Belongs to the 2H phosphoesterase superfamily. USB1 family. (258 aa)
SPPG_02335Uncharacterized protein. (325 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1041 aa)
SPPG_00981DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (139 aa)
SPPG_01277Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (360 aa)
SPPG_00910AAA_12 domain-containing protein. (1407 aa)
SPPG_01063Uncharacterized protein; Belongs to the argonaute family. (1006 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (382 aa)
SPPG_08895Uncharacterized protein. (86 aa)
SPPG_01019HRDC domain-containing protein. (872 aa)
SPPG_01555CID domain-containing protein. (762 aa)
SPPG_01134Uncharacterized protein. (275 aa)
SPPG_0117640S ribosomal protein S21; Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability. (86 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (593 aa)
SPPG_01236RNA_bind domain-containing protein. (715 aa)
SPPG_01506VacB and RNase II family 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (979 aa)
SPPG_01507Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (796 aa)
SPPG_00306Uncharacterized protein. (434 aa)
SPPG_08818DNA excision repair protein (Rad2). (1418 aa)
SPPG_01623TatD family hydrolase. (273 aa)
SPPG_0004118S rRNA biogenesis protein RCL1. (383 aa)
SPPG_00267TatD family hydrolase. (315 aa)
SPPG_0012620S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family. (528 aa)
SPPG_00125Uncharacterized protein. (335 aa)
SPPG_00164Uncharacterized protein. (855 aa)
SPPG_00387DNA polymerase. (1098 aa)
SPPG_00422Uncharacterized protein. (367 aa)
SPPG_00723Uncharacterized protein. (280 aa)
SPPG_00305Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (742 aa)
SPPG_00746DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (684 aa)
SPPG_00780HIT domain-containing protein. (342 aa)
SPPG_00449Uncharacterized protein; Belongs to the argonaute family. (909 aa)
SPPG_00513Lactamase_B domain-containing protein. (848 aa)
SPPG_00728Uncharacterized protein. (889 aa)
SPPG_006063'-5' exonuclease domain-containing protein. (633 aa)
SPPG_0061940S ribosomal protein S21; Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability. (86 aa)
SPPG_00795POP4 domain-containing protein. (273 aa)
SPPG_00833Endo/exonuclease/phosphatase domain-containing protein. (485 aa)
Your Current Organism:
Spizellomyces punctatus
NCBI taxonomy Id: 645134
Other names: S. punctatus DAOM BR117, Spizellomyces punctatus DAOM BR117
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