65 items (Spizellomyces punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SPPG_07397	Chromatin modification-related protein. (310 aa)
	SPPG_08857	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (754 aa)
	SPPG_00572	Chromatin modification-related protein. (299 aa)
	SPPG_08872	Uncharacterized protein. (191 aa)
	SPPG_00440	CMGC/CDK/CDK5 protein kinase; Belongs to the protein kinase superfamily. (294 aa)
	SPPG_00443	Uncharacterized protein. (1272 aa)
	SPPG_00254	KxDL domain-containing protein. (144 aa)
	SPPG_01636	Ubiquitin-40S ribosomal protein S27a. (158 aa)
	SPPG_00052	CAMK protein kinase. (650 aa)
	SPPG_01581	Chromatin modification-related protein. (234 aa)
	SPPG_01085	Uncharacterized protein. (1444 aa)
	SPPG_01303	Uncharacterized protein. (773 aa)
	SPPG_01219	Uncharacterized protein. (312 aa)
	SPPG_01158	STE/STE7/MEK1 protein kinase; Belongs to the protein kinase superfamily. (343 aa)
	SPPG_01146	DUF1767 domain-containing protein. (608 aa)
	SPPG_02268	PIPK domain-containing protein. (693 aa)
	SPPG_09003	Uncharacterized protein. (800 aa)
	SPPG_02148	WD_REPEATS_REGION domain-containing protein. (355 aa)
	SPPG_01881	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (328 aa)
	SPPG_01878	CAMK protein kinase. (606 aa)
	SPPG_02862	Uncharacterized protein. (291 aa)
	SPPG_02843	CMGC/CK2 protein kinase. (335 aa)
	SPPG_03052	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (654 aa)
	SPPG_02604	3'-5' exonuclease domain-containing protein. (1744 aa)
	SPPG_02557	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2721 aa)
	SPPG_03469	BUD32 protein kinase. (219 aa)
	SPPG_03613	Polyubiquitin. (243 aa)
	SPPG_03502	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (722 aa)
	SPPG_03959	Uncharacterized protein. (777 aa)
	SPPG_04098	CAMK/CAMKL/CHK1 protein kinase; Belongs to the protein kinase superfamily. (471 aa)
	SPPG_04768	STE/STE7 protein kinase; Belongs to the protein kinase superfamily. (371 aa)
	SPPG_04708	Uncharacterized protein. (202 aa)
	SPPG_03760	Uncharacterized protein. (1369 aa)
	SPPG_04491	Peptidyl-prolyl cis-trans isomerase. (188 aa)
	SPPG_05185	HAL protein kinase. (749 aa)
	MDM34	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (679 aa)
	SPPG_04545	HAL protein kinase. (607 aa)
	SPPG_05449	Bromo domain-containing protein. (743 aa)
	SPPG_06011	HAL protein kinase; Belongs to the protein kinase superfamily. (405 aa)
	SPPG_09338	Uncharacterized protein. (1218 aa)
	SPPG_06143	Uncharacterized protein. (2311 aa)
	SPPG_06203	Ubiquitin-40S ribosomal protein S27a. (158 aa)
	SPPG_06018	AGC protein kinase. (1457 aa)
	SPPG_06082	CMGC/CK2 protein kinase. (343 aa)
	SPPG_06334	Chromatin modification-related protein. (290 aa)
	SPPG_09398	Uncharacterized protein. (1098 aa)
	SPPG_06557	RecQ family ATP-dependent DNA helicase. (1150 aa)
	SPPG_06596	3'-5' exonuclease domain-containing protein. (521 aa)
	SPPG_06894	Uncharacterized protein. (1023 aa)
	SPPG_06646	Chromatin modification-related protein. (324 aa)
	SPPG_06307	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2326 aa)
	SPPG_06227	Polyubiquitin. (381 aa)
	SPPG_06988	BTP domain-containing protein. (328 aa)
	SPPG_08703	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (626 aa)
	SPPG_08745	Bromo domain-containing protein. (725 aa)
	SPPG_08696	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (227 aa)
	SPPG_08466	STE/STE7/MEK1 protein kinase. (364 aa)
	SPPG_08628	Uncharacterized protein. (296 aa)
	SPPG_08219	Uncharacterized protein. (3404 aa)
	SPPG_08506	HAL protein kinase; Belongs to the protein kinase superfamily. (455 aa)
	SPPG_08060	AGC/PDK1 protein kinase. (513 aa)
	SPPG_07955	CIA30 domain-containing protein. (202 aa)
	SPPG_08116	CAMK protein kinase; Belongs to the protein kinase superfamily. (460 aa)
	SPPG_09501	CAMK/CAMKL/LKB protein kinase. (861 aa)
	SPPG_07265	CMGC/CK2 protein kinase, variant; Belongs to the protein kinase superfamily. (394 aa)

Your Current Organism:

Spizellomyces punctatus

NCBI taxonomy Id: 645134
Other names: S. punctatus DAOM BR117, Spizellomyces punctatus DAOM BR117

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MDM34	SPPG_01881	A0A0L0HG62	A0A0L0HPA6	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.838
MDM34	SPPG_03502	A0A0L0HG62	A0A0L0HKY8	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	0.835
MDM34	SPPG_04708	A0A0L0HG62	A0A0L0HHT8	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Uncharacterized protein.	0.516
MDM34	SPPG_06894	A0A0L0HG62	A0A0L0HB07	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Uncharacterized protein.	0.833
MDM34	SPPG_08696	A0A0L0HG62	A0A0L0H4P4	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.838
SPPG_00052	SPPG_01636	A0A0L0HSI2	A0A0L0HSX0	CAMK protein kinase.	Ubiquitin-40S ribosomal protein S27a.	0.541
SPPG_00052	SPPG_02557	A0A0L0HSI2	A0A0L0HLW0	CAMK protein kinase.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.922
SPPG_00052	SPPG_02604	A0A0L0HSI2	A0A0L0HLY7	CAMK protein kinase.	3'-5' exonuclease domain-containing protein.	0.597
SPPG_00052	SPPG_03613	A0A0L0HSI2	A0A0L0HL87	CAMK protein kinase.	Polyubiquitin.	0.545
SPPG_00052	SPPG_03760	A0A0L0HSI2	A0A0L0HHS5	CAMK protein kinase.	Uncharacterized protein.	0.445
SPPG_00052	SPPG_04098	A0A0L0HSI2	A0A0L0HIR7	CAMK protein kinase.	CAMK/CAMKL/CHK1 protein kinase; Belongs to the protein kinase superfamily.	0.902
SPPG_00052	SPPG_04545	A0A0L0HSI2	A0A0L0HFG3	CAMK protein kinase.	HAL protein kinase.	0.769
SPPG_00052	SPPG_05185	A0A0L0HSI2	A0A0L0HG70	CAMK protein kinase.	HAL protein kinase.	0.773
SPPG_00052	SPPG_06011	A0A0L0HSI2	A0A0L0HD76	CAMK protein kinase.	HAL protein kinase; Belongs to the protein kinase superfamily.	0.766
SPPG_00052	SPPG_06203	A0A0L0HSI2	A0A0L0HC43	CAMK protein kinase.	Ubiquitin-40S ribosomal protein S27a.	0.541
SPPG_00052	SPPG_06227	A0A0L0HSI2	A0A0L0HAE3	CAMK protein kinase.	Polyubiquitin.	0.545
SPPG_00052	SPPG_06557	A0A0L0HSI2	A0A0L0HBP5	CAMK protein kinase.	RecQ family ATP-dependent DNA helicase.	0.523
SPPG_00052	SPPG_06596	A0A0L0HSI2	A0A0L0HBG0	CAMK protein kinase.	3'-5' exonuclease domain-containing protein.	0.597
SPPG_00052	SPPG_07955	A0A0L0HSI2	A0A0L0H6A8	CAMK protein kinase.	CIA30 domain-containing protein.	0.541
SPPG_00052	SPPG_08506	A0A0L0HSI2	A0A0L0H5Y8	CAMK protein kinase.	HAL protein kinase; Belongs to the protein kinase superfamily.	0.768