57 items (Spizellomyces punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SPPG_02557	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2721 aa)
	SPPG_01982	RECA_2 domain-containing protein. (366 aa)
	SPPG_01909	ERCC4 domain-containing protein. (305 aa)
	SPPG_02862	Uncharacterized protein. (291 aa)
	SPPG_03052	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (654 aa)
	SPPG_02755	Uncharacterized protein. (1131 aa)
	SPPG_02604	3'-5' exonuclease domain-containing protein. (1744 aa)
	SPPG_03613	Polyubiquitin. (243 aa)
	SPPG_09105	FHA domain-containing protein. (749 aa)
	SPPG_03085	RAN protein kinase. (388 aa)
	SPPG_04076	Uncharacterized protein. (266 aa)
	SPPG_03882	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (339 aa)
	SPPG_04098	CAMK/CAMKL/CHK1 protein kinase; Belongs to the protein kinase superfamily. (471 aa)
	SPPG_03086	RAN protein kinase; Belongs to the protein kinase superfamily. (401 aa)
	SPPG_03752	Recombination protein rad52. (579 aa)
	SPPG_03844	Uncharacterized protein. (197 aa)
	SPPG_07094	Uncharacterized protein. (291 aa)
	SPPG_06703	Serine/threonine-protein phosphatase. (305 aa)
	SPPG_06227	Polyubiquitin. (381 aa)
	SPPG_06337	Uncharacterized protein. (602 aa)
	SPPG_06596	3'-5' exonuclease domain-containing protein. (521 aa)
	SPPG_06557	RecQ family ATP-dependent DNA helicase. (1150 aa)
	SPPG_06203	Ubiquitin-40S ribosomal protein S27a. (158 aa)
	SPPG_05374	Uncharacterized protein. (268 aa)
	SPPG_09328	Uncharacterized protein. (383 aa)
	SPPG_06011	HAL protein kinase; Belongs to the protein kinase superfamily. (405 aa)
	SPPG_05247	Uncharacterized protein. (383 aa)
	SPPG_04707	RECA_2 domain-containing protein. (345 aa)
	SPPG_03760	Uncharacterized protein. (1369 aa)
	SPPG_05164	Uncharacterized protein. (504 aa)
	SPPG_04545	HAL protein kinase. (607 aa)
	SPPG_05185	HAL protein kinase. (749 aa)
	SPPG_08596	Poly [ADP-ribose] polymerase. (675 aa)
	SPPG_08367	FHA domain-containing protein. (553 aa)
	SPPG_08506	HAL protein kinase; Belongs to the protein kinase superfamily. (455 aa)
	SPPG_01296	Poly [ADP-ribose] polymerase. (1017 aa)
	SPPG_01636	Ubiquitin-40S ribosomal protein S27a. (158 aa)
	SPPG_00254	KxDL domain-containing protein. (144 aa)
	SPPG_00539	Uncharacterized protein. (457 aa)
	SPPG_00544	Asparagine-tRNA ligase. (577 aa)
	SPPG_08857	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (754 aa)
	SPPG_00804	RECA_2 domain-containing protein. (365 aa)
	SPPG_07955	CIA30 domain-containing protein. (202 aa)
	SPPG_08097	Uncharacterized protein. (217 aa)
	SPPG_08010	Histone H2B; Belongs to the histone H2B family. (132 aa)
	SPPG_07275	Uncharacterized protein. (1094 aa)
	SPPG_07230	Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (268 aa)
	SPPG_07065	FHA domain-containing protein. (1540 aa)
	SLX1	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (593 aa)
	SPPG_01303	Uncharacterized protein. (773 aa)
	SPPG_01027	Serine/threonine-protein phosphatase. (379 aa)
	SPPG_01146	DUF1767 domain-containing protein. (608 aa)
	SPPG_00910	AAA_12 domain-containing protein. (1407 aa)
	SPPG_01071	MPN domain-containing protein. (260 aa)
	SPPG_02229	Uncharacterized protein. (3324 aa)
	SPPG_02019	Uncharacterized protein. (1082 aa)
	SPPG_02345	Histone H2B; Belongs to the histone H2B family. (132 aa)

Your Current Organism:

Spizellomyces punctatus

NCBI taxonomy Id: 645134
Other names: S. punctatus DAOM BR117, Spizellomyces punctatus DAOM BR117

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SLX1	SPPG_00544	A0A0L0HSB3	A0A0L0HVD6	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	Asparagine-tRNA ligase.	0.962
SLX1	SPPG_00804	A0A0L0HSB3	A0A0L0HW80	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	RECA_2 domain-containing protein.	0.659
SLX1	SPPG_00910	A0A0L0HSB3	A0A0L0HR60	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	AAA_12 domain-containing protein.	0.678
SLX1	SPPG_01146	A0A0L0HSB3	A0A0L0HRI4	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	DUF1767 domain-containing protein.	0.865
SLX1	SPPG_01303	A0A0L0HSB3	A0A0L0HRU1	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	Uncharacterized protein.	0.614
SLX1	SPPG_01909	A0A0L0HSB3	A0A0L0HP43	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	ERCC4 domain-containing protein.	0.868
SLX1	SPPG_01982	A0A0L0HSB3	A0A0L0HP80	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	RECA_2 domain-containing protein.	0.691
SLX1	SPPG_02229	A0A0L0HSB3	A0A0L0HQ47	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	Uncharacterized protein.	0.602
SLX1	SPPG_02604	A0A0L0HSB3	A0A0L0HLY7	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	3'-5' exonuclease domain-containing protein.	0.994
SLX1	SPPG_02755	A0A0L0HSB3	A0A0L0HME2	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	Uncharacterized protein.	0.953
SLX1	SPPG_02862	A0A0L0HSB3	A0A0L0HMT8	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	Uncharacterized protein.	0.544
SLX1	SPPG_03752	A0A0L0HSB3	A0A0L0HIH5	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	Recombination protein rad52.	0.529
SLX1	SPPG_03760	A0A0L0HSB3	A0A0L0HHS5	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	Uncharacterized protein.	0.484
SLX1	SPPG_03882	A0A0L0HSB3	A0A0L0HIW5	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.783
SLX1	SPPG_04707	A0A0L0HSB3	A0A0L0HGZ2	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	RECA_2 domain-containing protein.	0.647
SLX1	SPPG_06557	A0A0L0HSB3	A0A0L0HBP5	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	RecQ family ATP-dependent DNA helicase.	0.946
SLX1	SPPG_06596	A0A0L0HSB3	A0A0L0HBG0	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	3'-5' exonuclease domain-containing protein.	0.994
SLX1	SPPG_07094	A0A0L0HSB3	A0A0L0H9E7	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	Uncharacterized protein.	0.618
SLX1	SPPG_08857	A0A0L0HSB3	A0A0L0HVJ1	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.858
SPPG_00254	SPPG_01636	A0A0L0HT49	A0A0L0HSX0	KxDL domain-containing protein.	Ubiquitin-40S ribosomal protein S27a.	0.621