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SPPG_04835 SPPG_04835 SPPG_07315 SPPG_07315 SPPG_07507 SPPG_07507 SPPG_07544 SPPG_07544 SPPG_07384 SPPG_07384 SPPG_07606 SPPG_07606 SPPG_07240 SPPG_07240 SPPG_07291 SPPG_07291 SPPG_06989 SPPG_06989 SPPG_07037 SPPG_07037 SPPG_06764 SPPG_06764 SPPG_06317 SPPG_06317 SPPG_05762 SPPG_05762 SPPG_06486 SPPG_06486 SPPG_05806 SPPG_05806 SPPG_06140 SPPG_06140 SPPG_06716 SPPG_06716 SPPG_06076 SPPG_06076 SPPG_06325 SPPG_06325 SPPG_05967 SPPG_05967 SPPG_05875 SPPG_05875 SPPG_05922 SPPG_05922 SPPG_05868 SPPG_05868 SPPG_04982 SPPG_04982 SPPG_05470 SPPG_05470 SPPG_05103 SPPG_05103 SPPG_05533 SPPG_05533 SPPG_05602 SPPG_05602 SPPG_04975 SPPG_04975 SPPG_04931 SPPG_04931 SPPG_05108 SPPG_05108 SPPG_04591 SPPG_04591 SPPG_05278 SPPG_05278 SPPG_05170 SPPG_05170 SPPG_09222 SPPG_09222 SPPG_05246 SPPG_05246 SPPG_04557 SPPG_04557 SPPG_04565 SPPG_04565 SPPG_04641 SPPG_04641 SPPG_03907 SPPG_03907 SPPG_04756 SPPG_04756 SPPG_04793 SPPG_04793 SPPG_04856 SPPG_04856 SPPG_03763 SPPG_03763 TRM8 TRM8 SPPG_04772 SPPG_04772 SPPG_04173 SPPG_04173 SPPG_04858 SPPG_04858 SPPG_07465 SPPG_07465 SPPG_03896 SPPG_03896 SPPG_04291 SPPG_04291 SPPG_03783 SPPG_03783 SPPG_03952 SPPG_03952 SPPG_03967 SPPG_03967 SPPG_03828 SPPG_03828 SPPG_04103 SPPG_04103 SPPG_03189 SPPG_03189 SPPG_04180 SPPG_04180 SPPG_04220 SPPG_04220 SPPG_04331 SPPG_04331 SPPG_03621 SPPG_03621 SPPG_03626 SPPG_03626 SPPG_03200 SPPG_03200 SPPG_03551 SPPG_03551 SPPG_03340 SPPG_03340 SPPG_03696 SPPG_03696 SPPG_02439 SPPG_02439 SPPG_02759 SPPG_02759 SPPG_03585 SPPG_03585 SPPG_02627 SPPG_02627 SPPG_02736 SPPG_02736 SPPG_02837 SPPG_02837 SPPG_01834 SPPG_01834 SPPG_02758 SPPG_02758 SPPG_02970 SPPG_02970 SPPG_03024 SPPG_03024 SPPG_02880 SPPG_02880 SPPG_01726 SPPG_01726 SPPG_02931 SPPG_02931 SPPG_01694 SPPG_01694 SPPG_01713 SPPG_01713 SPPG_01920 SPPG_01920 SPPG_00944 SPPG_00944 SPPG_02228 SPPG_02228 SPPG_01012 SPPG_01012 SPPG_08983 SPPG_08983 SPPG_01067 SPPG_01067 SPPG_02373 SPPG_02373 SPPG_02410 SPPG_02410 SPPG_00961 SPPG_00961 SPPG_01242 SPPG_01242 SPPG_01058 SPPG_01058 SPPG_01043 SPPG_01043 SPPG_00973 SPPG_00973 SPPG_01050 SPPG_01050 SPPG_01243 SPPG_01243 SPPG_01528 SPPG_01528 SPPG_01329 SPPG_01329 SPPG_07763 SPPG_07763 SPPG_07731 SPPG_07731 SPPG_08011 SPPG_08011 SPPG_08301 SPPG_08301 SPPG_08746 SPPG_08746 SPPG_08493 SPPG_08493 SPPG_08580 SPPG_08580 SPPG_08075 SPPG_08075 SPPG_08713 SPPG_08713 SPPG_00091 SPPG_00091 SPPG_00161 SPPG_00161 SPPG_00226 SPPG_00226 SPPG_00262 SPPG_00262 SPPG_00159 SPPG_00159 SPPG_00340 SPPG_00340 SPPG_08854 SPPG_08854 SPPG_00543 SPPG_00543 SPPG_00575 SPPG_00575 SPPG_00506 SPPG_00506 SPPG_00790 SPPG_00790 SPPG_01440 SPPG_01440 SPPG_00047 SPPG_00047 SPPG_00095 SPPG_00095 SPPG_01405 SPPG_01405 SPPG_01481 SPPG_01481 SPPG_01536 SPPG_01536 SPPG_09502 SPPG_09502 SPPG_07901 SPPG_07901 SPPG_07599 SPPG_07599 SPPG_07716 SPPG_07716 SPPG_07505 SPPG_07505 SPPG_09490 SPPG_09490 SPPG_07251 SPPG_07251
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPPG_04835Uncharacterized protein. (751 aa)
SPPG_07315Malate synthase; Belongs to the malate synthase family. (543 aa)
SPPG_07507PALP domain-containing protein. (405 aa)
SPPG_07544S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (379 aa)
SPPG_07384Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1052 aa)
SPPG_07606Uncharacterized protein. (1089 aa)
SPPG_07240Methylmalonyl-CoA epimerase. (166 aa)
SPPG_07291Uncharacterized protein. (354 aa)
SPPG_06989Ribose 5-phosphate isomerase A. (250 aa)
SPPG_07037Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (367 aa)
SPPG_06764Pyruvate kinase; Belongs to the pyruvate kinase family. (495 aa)
SPPG_06317Citrate synthase; Belongs to the citrate synthase family. (464 aa)
SPPG_057626-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (512 aa)
SPPG_06486Fumarate hydratase, mitochondrial. (466 aa)
SPPG_05806Uncharacterized protein. (610 aa)
SPPG_06140Ribose-phosphate pyrophosphokinase 3. (362 aa)
SPPG_06716Citrate synthase; Belongs to the citrate synthase family. (502 aa)
SPPG_06076Dihydrolipoyl dehydrogenase. (504 aa)
SPPG_06325Cysteine synthase. (367 aa)
SPPG_05967Threonine dehydratase. (660 aa)
SPPG_05875Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (642 aa)
SPPG_05922Peripheral subunit-binding (PSBD) domain-containing protein. (363 aa)
SPPG_05868Aspartate aminotransferase. (432 aa)
SPPG_04982Uncharacterized protein. (1022 aa)
SPPG_05470Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (740 aa)
SPPG_05103Methylmalonyl-CoA mutase, mitochondrial. (757 aa)
SPPG_05533Ribose-phosphate diphosphokinase. (331 aa)
SPPG_05602Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. (1118 aa)
SPPG_04975Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (155 aa)
SPPG_04931Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (338 aa)
SPPG_05108Malic enzyme. (646 aa)
SPPG_04591Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (394 aa)
SPPG_05278Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (291 aa)
SPPG_051703-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (563 aa)
SPPG_09222Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (494 aa)
SPPG_05246Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (767 aa)
SPPG_04557Citrate synthase; Belongs to the citrate synthase family. (534 aa)
SPPG_04565Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (512 aa)
SPPG_04641Uncharacterized protein. (443 aa)
SPPG_03907Glucose-6-phosphate isomerase; Belongs to the GPI family. (564 aa)
SPPG_04756Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
SPPG_04793APH domain-containing protein. (383 aa)
SPPG_04856Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (712 aa)
SPPG_03763Methylmalonate-semialdehyde dehydrogenase (Acylating). (539 aa)
TRM8tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (286 aa)
SPPG_04772Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (416 aa)
SPPG_04173SCP2 domain-containing protein. (765 aa)
SPPG_04858Signal peptide peptidase SppA, 67K type. (660 aa)
SPPG_07465Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (363 aa)
SPPG_0389625S rRNA adenine-N(1) methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA; Belongs to the BMT2 family. (280 aa)
SPPG_04291FBPase domain-containing protein; Belongs to the FBPase class 1 family. (346 aa)
SPPG_03783PALP domain-containing protein. (338 aa)
SPPG_03952Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (223 aa)
SPPG_03967Aminotran_1_2 domain-containing protein. (426 aa)
SPPG_03828ATP-grasp domain-containing protein. (462 aa)
SPPG_04103Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (416 aa)
SPPG_03189RpiB/LacA/LacB family sugar-phosphate isomerase. (175 aa)
SPPG_04180Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (171 aa)
SPPG_04220Uncharacterized protein. (358 aa)
SPPG_04331SET domain-containing protein. (626 aa)
SPPG_03621Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (590 aa)
SPPG_03626O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase. (445 aa)
SPPG_03200Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (360 aa)
SPPG_03551Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (453 aa)
SPPG_03340SGL domain-containing protein. (326 aa)
SPPG_03696Ribose-phosphate diphosphokinase. (457 aa)
SPPG_02439Transketolase. (676 aa)
SPPG_02759Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (689 aa)
SPPG_03585Uncharacterized protein. (335 aa)
SPPG_02627Aminotran_1_2 domain-containing protein. (565 aa)
SPPG_02736Pyruvate kinase; Belongs to the pyruvate kinase family. (493 aa)
SPPG_02837Fumarate hydratase, mitochondrial. (492 aa)
SPPG_01834Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (321 aa)
SPPG_02758Uncharacterized protein. (260 aa)
SPPG_02970Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (514 aa)
SPPG_03024Phosphoserine phosphatase SerB. (637 aa)
SPPG_02880Bms1-type G domain-containing protein. (817 aa)
SPPG_01726Glyceraldehyde-3-phosphate dehydrogenase. (348 aa)
SPPG_02931Uncharacterized protein. (607 aa)
SPPG_01694Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (706 aa)
SPPG_01713Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (409 aa)
SPPG_01920Isocitrate lyase. (539 aa)
SPPG_00944Aminotran_5 domain-containing protein. (419 aa)
SPPG_02228Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (468 aa)
SPPG_01012Triosephosphate isomerase. (250 aa)
SPPG_08983WD_REPEATS_REGION domain-containing protein. (773 aa)
SPPG_01067Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. (168 aa)
SPPG_02373Phosphotransferase. (502 aa)
SPPG_02410Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (784 aa)
SPPG_00961Dihydroxyacetone kinase. (769 aa)
SPPG_01242Probable acetate kinase. (430 aa)
SPPG_01058Uncharacterized protein. (309 aa)
SPPG_01043L-serine ammonia-lyase. (607 aa)
SPPG_00973Phosphotransferase. (518 aa)
SPPG_01050Uncharacterized protein. (1264 aa)
SPPG_01243Glyceraldehyde-3-phosphate dehydrogenase. (337 aa)
SPPG_01528Uncharacterized protein. (306 aa)
SPPG_01329Uncharacterized protein. (328 aa)
SPPG_07763Uncharacterized protein. (606 aa)
SPPG_07731ATPase_AAA_core domain-containing protein. (307 aa)
SPPG_08011Lipoyl-binding domain-containing protein. (461 aa)
SPPG_08301Mac domain-containing protein. (201 aa)
SPPG_08746Succinate dehydrogenase [ubiquinone] cytochrome b small subunit. (178 aa)
SPPG_08493Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (730 aa)
SPPG_08580Succinate-CoA ligase subunit beta. (449 aa)
SPPG_08075Propionyl-CoA carboxylase beta chain, mitochondrial. (554 aa)
SPPG_08713Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1211 aa)
SPPG_00091SET domain-containing protein. (428 aa)
SPPG_00161Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (671 aa)
SPPG_00226Malate dehydrogenase. (333 aa)
SPPG_00262Citrate synthase; Belongs to the citrate synthase family. (671 aa)
SPPG_00159PALP domain-containing protein. (383 aa)
SPPG_00340Malate dehydrogenase. (318 aa)
SPPG_08854Succinate dehydrogenase, cytochrome b556 subunit. (192 aa)
SPPG_00543Enolase. (300 aa)
SPPG_00575Phosphoserine aminotransferase. (383 aa)
SPPG_005062,3-bisphosphoglycerate-independent phosphoglycerate mutase. (509 aa)
SPPG_007906-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (246 aa)
SPPG_01440Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (281 aa)
SPPG_00047Uncharacterized protein. (324 aa)
SPPG_00095Gluconokinase; Belongs to the gluconokinase GntK/GntV family. (185 aa)
SPPG_01405Phosphoenolpyruvate carboxykinase [ATP]. (544 aa)
SPPG_01481Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (399 aa)
SPPG_01536D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (426 aa)
SPPG_09502Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (789 aa)
SPPG_07901ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (1069 aa)
SPPG_07599SET domain-containing protein. (572 aa)
SPPG_07716Pyruvate kinase; Belongs to the pyruvate kinase family. (624 aa)
SPPG_07505S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (290 aa)
SPPG_09490Uncharacterized protein. (129 aa)
SPPG_07251Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
Your Current Organism:
Spizellomyces punctatus
NCBI taxonomy Id: 645134
Other names: S. punctatus DAOM BR117, Spizellomyces punctatus DAOM BR117
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