STRINGSTRING
rplI rplI EFF89768.1 EFF89768.1 EFF88172.1 EFF88172.1 EFF88170.1 EFF88170.1 EFF88199.1 EFF88199.1 EFF88356.1 EFF88356.1 rpmJ-2 rpmJ-2 rpmG-4 rpmG-4 EFF88412.1 EFF88412.1 EFF88625.1 EFF88625.1 gvpA-2 gvpA-2 rpmG-3 rpmG-3 rpmB-2 rpmB-2 rpsN rpsN EFF89391.1 EFF89391.1 EFF89390.1 EFF89390.1 EFF89346.1 EFF89346.1 EFF89345.1 EFF89345.1 rpsR-2 rpsR-2 rpmE2 rpmE2 rpmG-2 rpmG-2 EFF89074.1 EFF89074.1 EFF89046.1 EFF89046.1 EFF89031.1 EFF89031.1 EFF93950.1 EFF93950.1 EFF93947.1 EFF93947.1 gvpA gvpA EFF93941.1 EFF93941.1 EFF93548.1 EFF93548.1 EFF93532.1 EFF93532.1 EFF93524.1 EFF93524.1 EFF93519.1 EFF93519.1 rpsO rpsO rpsB rpsB rplS rplS rimM rimM rpsP rpsP EFF93312.1 EFF93312.1 EFF93311.1 EFF93311.1 rpmF rpmF rpmB rpmB rpmE rpmE EFF93063.1 EFF93063.1 EFF93024.1 EFF93024.1 EFF92997.1 EFF92997.1 EFF92967.1 EFF92967.1 EFF92966.1 EFF92966.1 rpsI rpsI rplM rplM rplQ rplQ rpsK rpsK rpsM rpsM rpmJ rpmJ rplO rplO rpmD rpmD rpsE rpsE rplR rplR rplF rplF rpsH rpsH rpsZ rpsZ rplE rplE rplX rplX rplN rplN rpsQ rpsQ rpmC rpmC rplP rplP rpsC rpsC rplV rplV rpsS rpsS rplB rplB rplW rplW rplD rplD rplC rplC rpsJ rpsJ rpsG rpsG rpsL rpsL rplL rplL rplJ rplJ EFF92544.1 EFF92544.1 rplK rplK rpmG rpmG EFF92492.1 EFF92492.1 EFF92441.1 EFF92441.1 recR recR EFF92229.1 EFF92229.1 EFF92168.1 EFF92168.1 EFF92113.1 EFF92113.1 EFF92042.1 EFF92042.1 EFF92026.1 EFF92026.1 gyrB gyrB rpmH rpmH EFF92013.1 EFF92013.1 EFF92012.1 EFF92012.1 rpsF rpsF rpsR rpsR EFF91987.1 EFF91987.1 EFF91584.1 EFF91584.1 EFF91567.1 EFF91567.1 rplY rplY EFF91468.1 EFF91468.1 EFF91301.1 EFF91301.1 EFF91299.1 EFF91299.1 clpS clpS EFF91142.1 EFF91142.1 EFF91031.1 EFF91031.1 rplU rplU rpmA rpmA rpsT rpsT recO recO dnaG dnaG EFF90804.1 EFF90804.1 EFF90798.1 EFF90798.1 EFF90770.1 EFF90770.1 EFF90745.1 EFF90745.1 EFF90652.1 EFF90652.1 EFF90479.1 EFF90479.1 EFF90478.1 EFF90478.1 EFF90477.1 EFF90477.1 EFF90454.1 EFF90454.1 EFF90281.1 EFF90281.1 rpmI rpmI rplT rplT EFF90038.1 EFF90038.1 EFF90033.1 EFF90033.1 rpsD rpsD priA priA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rplI50S ribosomal protein L9; Binds to the 23S rRNA. (148 aa)
EFF89768.150S ribosomal protein L31. (91 aa)
EFF88172.1Conserved hypothetical protein. (1193 aa)
EFF88170.1Cobyrinic Acid a,c-diamide synthase. (264 aa)
EFF88199.1RecQ family ATP-dependent DNA helicase. (246 aa)
EFF88356.1Restriction endonuclease superfamily protein. (579 aa)
rpmJ-250S ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. (40 aa)
rpmG-450S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (54 aa)
EFF88412.1RecQ family ATP-dependent DNA helicase. (119 aa)
EFF88625.1PE-PGRS family protein. (294 aa)
gvpA-2Gas vesicle structural protein; Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure. (123 aa)
rpmG-350S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (54 aa)
rpmB-2Ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. (78 aa)
rpsNRibosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa)
EFF89391.1Plasmid partitioning protein, ParA1. (419 aa)
EFF89390.1Plasmid partitioning protein; Truncated CDS. (242 aa)
EFF89346.1Bacteriocin CFP29. (266 aa)
EFF89345.1Dyp-type peroxidase. (327 aa)
rpsR-230S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (78 aa)
rpmE250S ribosomal protein L31. (85 aa)
rpmG-250S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (54 aa)
EFF89074.1Ribosomal protein L2. (86 aa)
EFF89046.1DNA gyrase, B subunit. (211 aa)
EFF89031.1Conserved hypothetical protein. (397 aa)
EFF93950.1Gas vesicle protein K. (93 aa)
EFF93947.1Gas vesicle protein J; Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. (113 aa)
gvpAGas vesicle structural protein; Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure. (143 aa)
EFF93941.1Gas vesicle synthesis protein. (128 aa)
EFF93548.1DNA gyrase, A subunit. (818 aa)
EFF93532.1DNA gyrase, B subunit. (707 aa)
EFF93524.1RecQ family ATP-dependent DNA helicase. (729 aa)
EFF93519.1Hydrolase; Truncated CDS. (137 aa)
rpsO30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (96 aa)
rpsBRibosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (303 aa)
rplS50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (116 aa)
rimM16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (202 aa)
rpsPRibosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (139 aa)
EFF93312.1Conserved hypothetical protein. (528 aa)
EFF93311.1Conserved hypothetical protein. (476 aa)
rpmF50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (57 aa)
rpmB50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. (61 aa)
rpmE50S ribosomal protein L31; Binds the 23S rRNA. (74 aa)
EFF93063.1Conserved hypothetical protein. (264 aa)
EFF93024.1Cyclic nucleotide-binding domain-containing protein. (468 aa)
EFF92997.1Conserved hypothetical protein; Belongs to the SOS response-associated peptidase family. (271 aa)
EFF92967.1ATP-dependent DNA helicase. (308 aa)
EFF92966.1ATP-dependent DNA helicase. (392 aa)
rpsIRibosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (174 aa)
rplM50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (147 aa)
rplQRibosomal protein L17. (168 aa)
rpsK30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (134 aa)
rpsM30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (126 aa)
rpmJ50S ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. (37 aa)
rplO50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (151 aa)
rpmD50S ribosomal protein L30. (60 aa)
rpsERibosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (201 aa)
rplR50S ribosomal protein L18p/L5e; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (127 aa)
rplF50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (179 aa)
rpsH30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa)
rpsZ30S ribosomal protein S14p/S29e; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa)
rplERibosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (185 aa)
rplX50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (107 aa)
rplN50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rpsQ30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (94 aa)
rpmCRibosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (75 aa)
rplP50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (139 aa)
rpsCRibosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (276 aa)
rplV50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (123 aa)
rpsS30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (93 aa)
rplB50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (278 aa)
rplWRibosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (139 aa)
rplD50S ribosomal protein L4/L1; Forms part of the polypeptide exit tunnel. (218 aa)
rplC50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (214 aa)
rpsJ30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
rpsG30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
rpsL30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (123 aa)
rplL50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (135 aa)
rplJRibosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (176 aa)
EFF92544.150S ribosomal protein L1; Unextendable partial coding region; Belongs to the universal ribosomal protein uL1 family. (240 aa)
rplK50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (144 aa)
rpmG50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (54 aa)
EFF92492.1RecQ family ATP-dependent DNA helicase. (687 aa)
EFF92441.1Conserved hypothetical protein. (435 aa)
recRRecombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (199 aa)
EFF92229.1Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (114 aa)
EFF92168.1Integral membrane protein. (334 aa)
EFF92113.1Conserved hypothetical protein. (96 aa)
EFF92042.1Nosiheptide resistance regulatory protein. (233 aa)
EFF92026.1DNA gyrase, A subunit; Truncated CDS; unextendable partial coding region. (685 aa)
gyrBDNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (685 aa)
rpmH50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. (45 aa)
EFF92013.1Sporulation initiation inhibitor protein Soj. (357 aa)
EFF92012.1ParB family protein; Belongs to the ParB family. (365 aa)
rpsF30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (96 aa)
rpsR30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (78 aa)
EFF91987.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (492 aa)
EFF91584.1ADP-ribosylglycohydrolase. (372 aa)
EFF91567.1Ribosylglycohydrolase. (828 aa)
rplY50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (198 aa)
EFF91468.1Conserved hypothetical protein. (151 aa)
EFF91301.1Conserved hypothetical protein. (129 aa)
EFF91299.1Conserved hypothetical protein. (486 aa)
clpSATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. (105 aa)
EFF91142.1Cupin superfamily protein. (332 aa)
EFF91031.1Nuclease domain-containing protein; Truncated CDS. (176 aa)
rplU50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (106 aa)
rpmA50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. (84 aa)
rpsT30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (88 aa)
recODNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. (248 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (638 aa)
EFF90804.1Conserved hypothetical protein; Truncated CDS. (504 aa)
EFF90798.1Membrane protein. (468 aa)
EFF90770.1Secreted protein. (175 aa)
EFF90745.1Abortive infection phage resistance protein. (607 aa)
EFF90652.1Conserved hypothetical protein. (410 aa)
EFF90479.1ADP-ribosylglycohydrolase superfamily protein. (462 aa)
EFF90478.1Conserved hypothetical protein. (252 aa)
EFF90477.1Membrane protein. (547 aa)
EFF90454.1Ribosomal protein S1. (496 aa)
EFF90281.1Soj family protein. (338 aa)
rpmI50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family. (64 aa)
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (127 aa)
EFF90038.1ATPase. (409 aa)
EFF90033.1AAA family ATPase. (451 aa)
rpsD30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (204 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (720 aa)
Your Current Organism:
Streptomyces sp. e14
NCBI taxonomy Id: 645465
Other names: S. sp. e14
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