STRINGSTRING
OHY96798.1 OHY96798.1 OHY97072.1 OHY97072.1 OHY93356.1 OHY93356.1 OHY93179.1 OHY93179.1 OHY93180.1 OHY93180.1 OHY93181.1 OHY93181.1 OHY91209.1 OHY91209.1 OHY91210.1 OHY91210.1 OHY91211.1 OHY91211.1 OHY91273.1 OHY91273.1 OHY89704.1 OHY89704.1 OHY89703.1 OHY89703.1 OHY89702.1 OHY89702.1 OHY91292.1 OHY91292.1 OHY91290.1 OHY91290.1 OHY94854.1 OHY94854.1 ppc ppc nuoC nuoC OHY95088.1 OHY95088.1 OHY95086.1 OHY95086.1 OHY94764.1 OHY94764.1 nuoH nuoH nuoI nuoI nuoK nuoK OHY95081.1 OHY95081.1 OHY95080.1 OHY95080.1 nuoN nuoN OHY95881.1 OHY95881.1 OHY88603.1 OHY88603.1 OHY88598.1 OHY88598.1 mdh mdh nqrB nqrB nqrE nqrE OHY93615.1 OHY93615.1 OHY92407.1 OHY92407.1 OHY88455.1 OHY88455.1 OHY92410.1 OHY92410.1 OHY92219.1 OHY92219.1 OHY92279.1 OHY92279.1 OHY92280.1 OHY92280.1 OHY92281.1 OHY92281.1 OHY92282.1 OHY92282.1 nqrE-2 nqrE-2 OHY91862.1 OHY91862.1 OHY91873.1 OHY91873.1 OHY90945.1 OHY90945.1 OHY90998.1 OHY90998.1 OHY90999.1 OHY90999.1 OHY91000.1 OHY91000.1 OHY90836.1 OHY90836.1 OHY90746.1 OHY90746.1 aceK aceK ubiE ubiE OHY90339.1 OHY90339.1 OHY89479.1 OHY89479.1 hycD hycD hycE hycE OHY89482.1 OHY89482.1 OHY89399.1 OHY89399.1 OHY89408.1 OHY89408.1 OHY96690.1 OHY96690.1 sucD sucD sucC sucC OHY96779.1 OHY96779.1 sdhB sdhB OHY96781.1 OHY96781.1 sdhD sdhD OHY96783.1 OHY96783.1 OHY96784.1 OHY96784.1 OHY96874.1 OHY96874.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OHY96798.1Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (547 aa)
OHY97072.1Malate synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology. (535 aa)
OHY93356.1Sulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (237 aa)
OHY93179.1Cyd operon protein YbgT; Derived by automated computational analysis using gene prediction method: Protein Homology. (36 aa)
OHY93180.1Cytochrome d ubiquinol oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
OHY93181.1Cytochrome d terminal oxidase subunit 1; Part of the aerobic respiratory chain; catalyzes the ubiquinol to ubiquinone; Derived by automated computational analysis using gene prediction method: Protein Homology. (523 aa)
OHY91209.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (962 aa)
OHY91210.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
OHY91211.1Formate dehydrogenase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
OHY91273.1Ubiquinone-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
OHY89704.1Fumarate reductase (quinol) flavoprotein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (594 aa)
OHY89703.1Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
OHY89702.1Fumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane; Belongs to the FrdC family. (132 aa)
OHY91292.1Nitrate reductase; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family. (151 aa)
OHY91290.1Ferredoxin-type protein NapG; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
OHY94854.1Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aconitase/IPM isomerase family. (865 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (877 aa)
nuoCNADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. (601 aa)
OHY95088.1NADH-quinone oxidoreductase subunit E; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
OHY95086.1NADH-quinone oxidoreductase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (912 aa)
OHY94764.1Cytochrome B; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (405 aa)
nuoHNADH-quinone oxidoreductase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (322 aa)
nuoINADH-quinone oxidoreductase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (180 aa)
nuoKNADH-quinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (102 aa)
OHY95081.1NADH-quinone oxidoreductase subunit L; Derived by automated computational analysis using gene prediction method: Protein Homology. (615 aa)
OHY95080.1NADH-quinone oxidoreductase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology. (514 aa)
nuoNNADH-quinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (487 aa)
OHY95881.1Trimethylamine N-oxide reductase I catalytic subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (830 aa)
OHY88603.1Aspartate ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (480 aa)
OHY88598.1Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (311 aa)
nqrBNADH:ubiquinone reductase (Na(+)-transporting) subunit B; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. (409 aa)
nqrENADH:ubiquinone reductase (Na(+)-transporting) subunit E; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family. (198 aa)
OHY93615.1Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
OHY92407.1Cytochrome-c oxidase, cbb3-type subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the heme-copper respiratory oxidase family. (474 aa)
OHY88455.1YjjI family glycine radical enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (508 aa)
OHY92410.1Cytochrome-c oxidase, cbb3-type subunit III; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. (327 aa)
OHY92219.12-methylcitrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (375 aa)
OHY92279.1Hydrogenase 2 large subunit; Involved in hydrogen uptake; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (567 aa)
OHY92280.1Ni/Fe-hydrogenase cytochrome b subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
OHY92281.1Hydrogenase 2 protein HybA; Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
OHY92282.1Hydrogenase 2 small subunit; Involved in hydrogen uptake; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
nqrE-2NADH:ubiquinone reductase (Na(+)-transporting) subunit E; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family. (199 aa)
OHY91862.1NADP-dependent isocitrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
OHY91873.1Spermidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (641 aa)
OHY90945.1Sulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
OHY90998.1Cytochrome d terminal oxidase subunit 1; Part of the aerobic respiratory chain; catalyzes the ubiquinol to ubiquinone; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa)
OHY90999.1Cytochrome d ubiquinol oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
OHY91000.1Cyd operon protein YbgT; Derived by automated computational analysis using gene prediction method: Protein Homology. (38 aa)
OHY90836.1Catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine; Derived by automated computational analysis using gene prediction method: Protein Homology. (826 aa)
OHY90746.1Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
aceKBifunctional isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (575 aa)
ubiEBifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (250 aa)
OHY90339.1Sulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
OHY89479.1Hydrogenase 4 subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (627 aa)
hycDHydrogenase 3 membrane subunit; Formate hydrogenlyase subunit 4; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
hycEHydrogenase 3 large subunit; Formate hydrogenlyase subunit 5; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa)
OHY89482.1Electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
OHY89399.1Sn-glycerol-3-phosphate dehydrogenase subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
OHY89408.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
OHY96690.1Cytochrome c nitrite reductase Fe-S protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
sucDsuccinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
sucCsuccinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
OHY96779.12-oxoglutarate dehydrogenase E1 component; Derived by automated computational analysis using gene prediction method: Protein Homology. (935 aa)
sdhBSuccinate dehydrogenase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (238 aa)
OHY96781.1Succinate dehydrogenase flavoprotein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa)
sdhDSuccinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (114 aa)
OHY96783.1Succinate dehydrogenase cytochrome b556 large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (125 aa)
OHY96784.1Citrate (Si)-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (428 aa)
OHY96874.1Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
Your Current Organism:
Aeromonas sobria
NCBI taxonomy Id: 646
Other names: A. sobria, ATCC 43979, Aeromonas hybridization group 7 (HG7), Aeromonas sp. TH002, Aeromonas sp. TH004, Aeromonas sp. TH005, Aeromonas sp. TH018, Aeromonas sp. TH032, Aeromonas sp. TH035, Aeromonas sp. TH037, Aeromonas sp. TH040, Aeromonas sp. TH070, Aeromonas sp. TH082, Aeromonas sp. TH103, Aeromonas sp. TH112, Aeromonas sp. TH116, Aeromonas sp. TH119, CCUG 14830, CECT 4245, CIP 74.33, DSM 19176, JCM 2139, LMG 3783, LMG:3783, NCTC 12979, strain 208
Server load: low (16%) [HD]