STRINGSTRING
AFM39344.1 AFM39344.1 AFM42850.1 AFM42850.1 AFM42845.1 AFM42845.1 AFM42810.1 AFM42810.1 AFM39276.1 AFM39276.1 AFM39223.1 AFM39223.1 AFM43341.1 AFM43341.1 AFM43361.1 AFM43361.1 AFM43370.1 AFM43370.1 AFM43387.1 AFM43387.1 AFM43227.1 AFM43227.1 AFM43093.1 AFM43093.1 AFM43334.1 AFM43334.1 AFM42776.1 AFM42776.1 AFM42761.1 AFM42761.1 AFM42713.1 AFM42713.1 AFM42624.1 AFM42624.1 AFM42500.1 AFM42500.1 AFM42482.1 AFM42482.1 AFM42456.1 AFM42456.1 AFM42313.1 AFM42313.1 AFM42306.1 AFM42306.1 AFM42095.1 AFM42095.1 AFM42091.1 AFM42091.1 AFM41877.1 AFM41877.1 AFM41704.1 AFM41704.1 AFM41573.1 AFM41573.1 AFM41502.1 AFM41502.1 AFM41496.1 AFM41496.1 AFM41450.1 AFM41450.1 AFM41449.1 AFM41449.1 AFM41333.1 AFM41333.1 AFM41155.1 AFM41155.1 AFM40932.1 AFM40932.1 AFM40762.1 AFM40762.1 AFM40706.1 AFM40706.1 AFM40701.1 AFM40701.1 AFM40515.1 AFM40515.1 AFM40285.1 AFM40285.1 AFM40127.1 AFM40127.1 AFM40068.1 AFM40068.1 hprK hprK AFM39952.1 AFM39952.1 AFM39937.1 AFM39937.1 AFM39892.1 AFM39892.1 AFM39888.1 AFM39888.1 AFM39887.1 AFM39887.1 AFM39862.1 AFM39862.1 AFM39749.1 AFM39749.1 AFM39729.1 AFM39729.1 AFM39625.1 AFM39625.1 AFM39619.1 AFM39619.1 AFM39461.1 AFM39461.1 AFM39380.1 AFM39380.1 AFM43057.1 AFM43057.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFM39344.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (474 aa)
AFM42850.1Signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold. (535 aa)
AFM42845.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (377 aa)
AFM42810.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (464 aa)
AFM39276.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (611 aa)
AFM39223.1PAS/PAC sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (474 aa)
AFM43341.1Putative regulator of cell autolysis; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (579 aa)
AFM43361.1Putative regulator of cell autolysis; PFAM: Histidine kinase; 5TMR of 5TMR-LYT; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (558 aa)
AFM43370.1PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Predicted histidine kinase sensor domain. (408 aa)
AFM43387.1Putative regulator of cell autolysis; PFAM: Histidine kinase; 7TM diverse intracellular signalling; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Glycosyl hydrolases family 2, sugar binding domain. (640 aa)
AFM43227.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (510 aa)
AFM43093.1Hypothetical protein. (170 aa)
AFM43334.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (443 aa)
AFM42776.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (463 aa)
AFM42761.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (390 aa)
AFM42713.1Chemotaxis protein histidine kinase-like protein; PFAM: CheW-like domain; P2 response regulator binding domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain. (716 aa)
AFM42624.1PAS domain S-box; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (456 aa)
AFM42500.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (616 aa)
AFM42482.1PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (492 aa)
AFM42456.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (464 aa)
AFM42313.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (591 aa)
AFM42306.1Hypothetical protein. (660 aa)
AFM42095.1Signal transduction histidine kinase, nitrogen specific; PFAM: His Kinase A (phosphoacceptor) domain. (371 aa)
AFM42091.1Signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold. (527 aa)
AFM41877.1PFAM: Histidine kinase; Sensor protein DegS; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (380 aa)
AFM41704.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (466 aa)
AFM41573.1PFAM: Histidine kinase; Ammonium Transporter Family; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; TIGRFAM: ammonium transporter. (643 aa)
AFM41502.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (351 aa)
AFM41496.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (329 aa)
AFM41450.1PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (381 aa)
AFM41449.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (491 aa)
AFM41333.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (633 aa)
AFM41155.1PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (520 aa)
AFM40932.1Osmosensitive K+ channel histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Osmosensitive K+ channel His kinase sensor domain; Universal stress protein family. (891 aa)
AFM40762.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (510 aa)
AFM40706.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (520 aa)
AFM40701.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (278 aa)
AFM40515.1PAS domain S-box; PFAM: PAS fold; TIGRFAM: PAS domain S-box. (637 aa)
AFM40285.1PFAM: 5TMR of 5TMR-LYT; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (362 aa)
AFM40127.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (415 aa)
AFM40068.1Putative regulator of cell autolysis; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (517 aa)
hprKHpr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] (290 aa)
AFM39952.1Osmosensitive K+ channel histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Osmosensitive K+ channel His kinase sensor domain; Universal stress protein family. (901 aa)
AFM39937.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (585 aa)
AFM39892.1Chemotaxis protein histidine kinase-like protein; PFAM: P2 response regulator binding domain; CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain. (694 aa)
AFM39888.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; TIGRFAM: PAS domain S-box. (716 aa)
AFM39887.1Signal transduction histidine kinase, nitrogen specific; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (343 aa)
AFM39862.1Signal transduction histidine kinase, nitrogen specific; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Uncharacterized ACR, YhhQ family COG1738. (443 aa)
AFM39749.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (412 aa)
AFM39729.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (499 aa)
AFM39625.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (379 aa)
AFM39619.1Hypothetical protein. (195 aa)
AFM39461.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (711 aa)
AFM39380.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (503 aa)
AFM43057.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (470 aa)
Your Current Organism:
Desulfosporosinus acidiphilus
NCBI taxonomy Id: 646529
Other names: D. acidiphilus SJ4, Desulfosporosinus acidiphilus DSM 22704, Desulfosporosinus acidiphilus SJ4, Desulfosporosinus acidiphilus str. SJ4, Desulfosporosinus acidiphilus strain SJ4, Desulfosporosinus sp. SJ4
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.