STRINGSTRING
AFM42295.1 AFM42295.1 AFM39224.1 AFM39224.1 AFM39345.1 AFM39345.1 AFM39360.1 AFM39360.1 AFM39361.1 AFM39361.1 AFM39381.1 AFM39381.1 AFM39460.1 AFM39460.1 AFM39620.1 AFM39620.1 AFM39624.1 AFM39624.1 AFM39671.1 AFM39671.1 AFM39704.1 AFM39704.1 AFM39715.1 AFM39715.1 AFM39718.1 AFM39718.1 AFM39720.1 AFM39720.1 AFM39730.1 AFM39730.1 AFM39737.1 AFM39737.1 AFM39750.1 AFM39750.1 cheB cheB AFM39898.1 AFM39898.1 AFM39938.1 AFM39938.1 AFM39953.1 AFM39953.1 AFM39955.1 AFM39955.1 AFM40069.1 AFM40069.1 AFM40128.1 AFM40128.1 AFM40175.1 AFM40175.1 AFM40286.1 AFM40286.1 AFM40354.1 AFM40354.1 AFM40355.1 AFM40355.1 AFM40566.1 AFM40566.1 AFM40687.1 AFM40687.1 AFM40688.1 AFM40688.1 AFM40689.1 AFM40689.1 AFM40705.1 AFM40705.1 AFM40761.1 AFM40761.1 AFM40933.1 AFM40933.1 AFM41177.1 AFM41177.1 AFM41229.1 AFM41229.1 AFM41332.1 AFM41332.1 AFM41497.1 AFM41497.1 AFM41503.1 AFM41503.1 AFM41572.1 AFM41572.1 AFM41580.1 AFM41580.1 AFM41581.1 AFM41581.1 AFM41587.1 AFM41587.1 AFM41588.1 AFM41588.1 AFM41590.1 AFM41590.1 AFM41703.1 AFM41703.1 AFM41763.1 AFM41763.1 AFM41868.1 AFM41868.1 AFM41876.1 AFM41876.1 AFM42020.1 AFM42020.1 AFM42090.1 AFM42090.1 AFM42221.1 AFM42221.1 AFM42307.1 AFM42307.1 AFM42457.1 AFM42457.1 AFM42483.1 AFM42483.1 AFM42501.1 AFM42501.1 AFM42625.1 AFM42625.1 AFM42699.1 AFM42699.1 cheB-2 cheB-2 AFM42762.1 AFM42762.1 AFM42775.1 AFM42775.1 AFM42811.1 AFM42811.1 AFM42846.1 AFM42846.1 AFM42851.1 AFM42851.1 AFM43058.1 AFM43058.1 AFM43228.1 AFM43228.1 AFM43333.1 AFM43333.1 AFM43340.1 AFM43340.1 AFM43360.1 AFM43360.1 AFM43365.1 AFM43365.1 AFM43374.1 AFM43374.1 AFM43386.1 AFM43386.1 AFM43485.1 AFM43485.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFM42295.1Diguanylate cyclase (GGDEF) domain-containing protein; PFAM: Metallo-beta-lactamase superfamily; GGDEF domain; Response regulator receiver domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (674 aa)
AFM39224.1Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; TIGRFAM: nitrogen regulation protein NR(I). (455 aa)
AFM39345.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (233 aa)
AFM39360.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain. (914 aa)
AFM39361.1PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family. (218 aa)
AFM39381.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (225 aa)
AFM39460.1Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain. (470 aa)
AFM39620.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (230 aa)
AFM39624.1Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain. (449 aa)
AFM39671.1PFAM: Response regulator receiver domain; CheC-like family. (287 aa)
AFM39704.1CheY-like receiver domain-containing protein; PFAM: Response regulator receiver domain. (145 aa)
AFM39715.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (1367 aa)
AFM39718.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (233 aa)
AFM39720.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain. (772 aa)
AFM39730.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (228 aa)
AFM39737.1PFAM: Response regulator receiver domain. (116 aa)
AFM39750.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (226 aa)
cheBChemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (356 aa)
AFM39898.1PFAM: Response regulator receiver domain. (133 aa)
AFM39938.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (232 aa)
AFM39953.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (227 aa)
AFM39955.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (226 aa)
AFM40069.1PFAM: Response regulator receiver domain. (536 aa)
AFM40128.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (228 aa)
AFM40175.1Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain. (140 aa)
AFM40286.1Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain. (131 aa)
AFM40354.1PFAM: Response regulator receiver domain. (106 aa)
AFM40355.1PFAM: GGDEF domain; Response regulator receiver domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (328 aa)
AFM40566.1Chemotaxis signal transduction protein; PFAM: CheW-like domain; Response regulator receiver domain. (290 aa)
AFM40687.1PFAM: Response regulator receiver domain. (120 aa)
AFM40688.1PAS/PAC sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (905 aa)
AFM40689.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain. (810 aa)
AFM40705.1Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain. (448 aa)
AFM40761.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (227 aa)
AFM40933.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (233 aa)
AFM41177.1Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain. (463 aa)
AFM41229.1Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain; YcbB domain. (287 aa)
AFM41332.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (230 aa)
AFM41497.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (223 aa)
AFM41503.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (225 aa)
AFM41572.1PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family. (215 aa)
AFM41580.1Response regulator containing CheY-like receiver and SARP domains; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (288 aa)
AFM41581.1PAS domain S-box; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (901 aa)
AFM41587.1Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain. (119 aa)
AFM41588.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain. (354 aa)
AFM41590.1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain. (909 aa)
AFM41703.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (230 aa)
AFM41763.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; manually curated; non-canonical start codon. (222 aa)
AFM41868.1Response regulator with putative antiterminator output domain; PFAM: Response regulator receiver domain; ANTAR domain; manually curated. (191 aa)
AFM41876.1PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family. (211 aa)
AFM42020.1Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. (265 aa)
AFM42090.1Response regulator of citrate/malate metabolism; PFAM: Response regulator receiver domain. (227 aa)
AFM42221.1Response regulator receiver protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. (272 aa)
AFM42307.1Response regulator of the LytR/AlgR family; PFAM: Response regulator receiver domain; LytTr DNA-binding domain. (242 aa)
AFM42457.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (232 aa)
AFM42483.1PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family. (213 aa)
AFM42501.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (229 aa)
AFM42625.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB. (228 aa)
AFM42699.1Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain. (120 aa)
cheB-2Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (393 aa)
AFM42762.1Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain. (452 aa)
AFM42775.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (230 aa)
AFM42811.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (233 aa)
AFM42846.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (229 aa)
AFM42851.1Response regulator of citrate/malate metabolism; PFAM: Response regulator receiver domain. (235 aa)
AFM43058.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (231 aa)
AFM43228.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (231 aa)
AFM43333.1Response regulator of citrate/malate metabolism; PFAM: IclR helix-turn-helix domain; Response regulator receiver domain. (208 aa)
AFM43340.1Response regulator containing CheY-like receiver and SARP domains; PFAM: Bacterial transcriptional activator domain; Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (373 aa)
AFM43360.1Response regulator of the LytR/AlgR family; PFAM: Response regulator receiver domain; LytTr DNA-binding domain. (255 aa)
AFM43365.1Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain; manually curated. (126 aa)
AFM43374.1PFAM: Response regulator receiver domain. (347 aa)
AFM43386.1Response regulator containing CheY-like receiver and SARP domains; PFAM: Response regulator receiver domain. (282 aa)
AFM43485.1Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain. (120 aa)
Your Current Organism:
Desulfosporosinus acidiphilus
NCBI taxonomy Id: 646529
Other names: D. acidiphilus SJ4, Desulfosporosinus acidiphilus DSM 22704, Desulfosporosinus acidiphilus SJ4, Desulfosporosinus acidiphilus str. SJ4, Desulfosporosinus acidiphilus strain SJ4, Desulfosporosinus sp. SJ4
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.