STRINGSTRING
pdxT pdxT AEH06006.1 AEH06006.1 cbiD cbiD rpoL rpoL tbp tbp AEH06036.1 AEH06036.1 AEH06051.1 AEH06051.1 cbiA cbiA AEH06068.1 AEH06068.1 AEH06073.1 AEH06073.1 thiC thiC purE purE tmk tmk AEH06123.1 AEH06123.1 AEH06124.1 AEH06124.1 pyrI pyrI AEH06128.1 AEH06128.1 AEH06139.1 AEH06139.1 AEH06144.1 AEH06144.1 AEH06148.1 AEH06148.1 prs prs AEH06188.1 AEH06188.1 purL purL cbiT cbiT AEH06208.1 AEH06208.1 AEH06217.1 AEH06217.1 AEH06219.1 AEH06219.1 AEH06223.1 AEH06223.1 purF purF purA purA AEH06249.1 AEH06249.1 bioB bioB AEH06264.1 AEH06264.1 pyrG pyrG guaAB guaAB AEH06278.1 AEH06278.1 AEH06320.1 AEH06320.1 AEH06321.1 AEH06321.1 mptE mptE AEH06331.1 AEH06331.1 purM purM AEH06372.1 AEH06372.1 queE queE AEH06381.1 AEH06381.1 AEH06459.1 AEH06459.1 nusA nusA rpoA2 rpoA2 AEH06468.1 AEH06468.1 AEH06469.1 AEH06469.1 AEH06470.1 AEH06470.1 AEH06471.1 AEH06471.1 rpoH rpoH thiI thiI thi4 thi4 AEH06497.1 AEH06497.1 ribK ribK ribB ribB AEH06500.1 AEH06500.1 AEH06508.1 AEH06508.1 cobD cobD mfnA mfnA AEH06539.1 AEH06539.1 AEH06546.1 AEH06546.1 pyrH pyrH AEH06552.1 AEH06552.1 pdxS pdxS purD purD hemC hemC purP purP coaD coaD AEH06590.1 AEH06590.1 AEH06629.1 AEH06629.1 AEH06630.1 AEH06630.1 pyrK pyrK AEH06642.1 AEH06642.1 AEH06651.1 AEH06651.1 pyrB pyrB cmk cmk adkA adkA AEH06667.1 AEH06667.1 AEH06673.1 AEH06673.1 polC polC mptA mptA tfe tfe tfb tfb AEH06697.1 AEH06697.1 polB polB priL priL AEH06717.1 AEH06717.1 cobS cobS dcd dcd purC purC purS purS hemL hemL guaB guaB mptD mptD AEH06829.1 AEH06829.1 AEH06846.1 AEH06846.1 thyA thyA AEH06877.1 AEH06877.1 AEH06912.1 AEH06912.1 AEH06913.1 AEH06913.1 AEH06941.1 AEH06941.1 AEH06944.1 AEH06944.1 hemA hemA AEH06965.1 AEH06965.1 AEH06971.1 AEH06971.1 rpoN rpoN AEH06976.1 AEH06976.1 mfnB mfnB pyrE pyrE nadK nadK purT purT AEH07024.1 AEH07024.1 AEH07025.1 AEH07025.1 ribL ribL guaAA guaAA AEH07036.1 AEH07036.1 AEH07037.1 AEH07037.1 AEH07043.1 AEH07043.1 trpA trpA trpB trpB trpF trpF trpE trpE trpD trpD AEH07053.1 AEH07053.1 pyrC pyrC AEH07078.1 AEH07078.1 nadA nadA AEH07137.1 AEH07137.1 bioD bioD AEH07146.1 AEH07146.1 dnaG dnaG hpt hpt AEH07215.1 AEH07215.1 fae-hps fae-hps AEH07219.1 AEH07219.1 AEH07228.1 AEH07228.1 moaC moaC cofG cofG pyrD pyrD AEH07241.1 AEH07241.1 priS priS lig lig AEH07248.1 AEH07248.1 serS serS AEH07262.1 AEH07262.1 bioA bioA AEH07306.1 AEH07306.1 ribH ribH AEH07331.1 AEH07331.1 AEH07338.1 AEH07338.1 AEH07358.1 AEH07358.1 AEH07359.1 AEH07359.1 AEH07360.1 AEH07360.1 nadE nadE arfB arfB AEH07366.1 AEH07366.1 AEH07398.1 AEH07398.1 pyrF pyrF atpD atpD atpB atpB atpA atpA atpF atpF atpC atpC purQ purQ AEH07449.1 AEH07449.1 AEH07453.1 AEH07453.1 mobA mobA ndk ndk AEH07479.1 AEH07479.1 AEH07481.1 AEH07481.1 AEH07485.1 AEH07485.1 queC queC purO purO AEH07499.1 AEH07499.1 moaA moaA cobQ cobQ AEH07515.1 AEH07515.1 bioW bioW carA carA thiL thiL AEH07572.1 AEH07572.1
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pdxTGlutamine amidotransferase subunit pdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (187 aa)
AEH06006.1PFAM: Cobalamin (vitamin B12) biosynthesis CbiG, core; KEGG: mae:Maeo_0036 cobalamin (vitamin B12) biosynthesis CbiG protein. (340 aa)
cbiDcobalt-precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (381 aa)
rpoLDNA-directed RNA polymerase subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. (101 aa)
tbpTATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (181 aa)
AEH06036.1PFAM: Cytidylyltransferase; KEGG: mae:Maeo_0401 RfaE bifunctional protein. (63 aa)
AEH06051.1KEGG: mif:Metin_1460 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. (644 aa)
cbiACobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source. (458 aa)
AEH06068.1KEGG: mae:Maeo_0513 molybdenum cofactor synthesis domain-containing protein; TIGRFAM: Molybdenum cofactor synthesis; PFAM: Molybdopterin binding. (162 aa)
AEH06073.1PFAM: Aspartate/homoserine dehydrogenase, NAD-binding; KEGG: mmq:MmarC5_0845 L-aspartate dehydrogenase. (134 aa)
thiCPhosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (426 aa)
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (157 aa)
tmkPFAM: Thymidylate kinase-like; TIGRFAM: Thymidylate kinase; HAMAP: Thymidylate kinase; KEGG: mae:Maeo_0344 thymidylate kinase. (195 aa)
AEH06123.1KEGG: mae:Maeo_0045 carbamoyl-phosphate synthase L chain ATP-binding; PFAM: MGS-like; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation; Carbamoyl phosphate synthetase, large subunit, ATP-binding. (603 aa)
AEH06124.1KEGG: mae:Maeo_0044 carbamoyl-phosphate synthase L chain ATP-binding; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation. (479 aa)
pyrIAspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase. (165 aa)
AEH06128.1KEGG: mae:Maeo_0202 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00454; PFAM: Nucleotidyl transferase. (192 aa)
AEH06139.1Transcription termination factor Tfs; SMART: Zinc finger, TFIIS-type; DNA-directed RNA polymerase, M/15kDa subunit; TIGRFAM: DNA-directed RNA polymerase, subunit M, archaeal; KEGG: mae:Maeo_0213 transcription termination factor Tfs; PFAM: Zinc finger, TFIIS-type; DNA-directed RNA polymerase, M/15kDa subunit; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (105 aa)
AEH06144.1KEGG: mmz:MmarC7_0560 2-oxoglutarate ferredoxin oxidoreductase subunit gamma; PFAM: Pyruvate/ketoisovalerate oxidoreductase. (178 aa)
AEH06148.1KEGG: mae:Maeo_0220 precorrin-6x reductase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobK/CbiJ, precorrin-6x reductase; PFAM: Cobalamin (vitamin B12) biosynthesis CobK/CbiJ, precorrin-6x reductase. (256 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (287 aa)
AEH06188.1DNA binding protein, Tfx family; KEGG: mae:Maeo_0719 putative transcriptional regulator; TIGRFAM: DNA-binding protein Tfx, archaea; PFAM: RNA polymerase sigma-70 region 4. (134 aa)
purLPhosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (734 aa)
cbiTcobalt-precorrin-6Y C(15)-methyltransferase (decarboxylating); Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7. (186 aa)
AEH06208.1dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (185 aa)
AEH06217.1UPF0218 protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (158 aa)
AEH06219.1TIGRFAM: DNA-directed RNA polymerase; KEGG: mae:Maeo_0280 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7, N-terminal; Ribosomal protein S1, RNA binding domain. (189 aa)
AEH06223.1KEGG: mae:Maeo_1460 molybdenum cofactor synthesis domain-containing protein; TIGRFAM: Molybdenum cofactor synthesis; PFAM: MoeA, N-terminal region, domain I/II; Molybdopterin binding; MoeA, C-terminal, domain IV. (403 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (456 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (336 aa)
AEH06249.1Precorrin-2 C20-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobI/CbiL, precorrin-2 C20-methyltransferase, core; KEGG: mae:Maeo_0248 precorrin-2 C20-methyltransferase; PFAM: Tetrapyrrole methylase. (235 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (326 aa)
AEH06264.1SMART: RNA polymerase Rbp10; KEGG: mae:Maeo_0178 RNA polymerase Rbp10. (46 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (546 aa)
guaABGMP synthase (glutamine-hydrolyzing) subunit B; Catalyzes the synthesis of GMP from XMP. (310 aa)
AEH06278.1PFAM: Cytidylyltransferase; TIGRFAM: Nicotinamide-nucleotide adenylyltransferase, archaeal type; Cytidyltransferase-related; HAMAP: Nicotinamide-nucleotide adenylyltransferase, archaeal type; KEGG: mae:Maeo_0254 nicotinamide-nucleotide adenylyltransferase. (170 aa)
AEH06320.1KEGG: mae:Maeo_0515 beta-lactamase domain-containing protein. (268 aa)
AEH06321.1Manually curated; TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic-like; KEGG: mae:Maeo_0516 anaerobic ribonucleoside-triphosphate reductase activating protein; PFAM: Radical SAM. (240 aa)
mptEProtein of unknown function DUF115; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. (251 aa)
AEH06331.1PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; KEGG: mae:Maeo_0938 NADH ubiquinone oxidoreductase 20 kDa subunit. (251 aa)
purMTIGRFAM: Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: mmq:MmarC5_0337 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein. (350 aa)
AEH06372.1precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; KEGG: mae:Maeo_0830 precorrin-3B C17-methyltransferase; PFAM: Tetrapyrrole methylase. (252 aa)
queERadical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (246 aa)
AEH06381.1PFAM: 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; KEGG: mfs:MFS40622_0108 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase. (259 aa)
AEH06459.1KEGG: fpl:Ferp_1321 rhodanese domain protein; PFAM: Rhodanese-like; SMART: Rhodanese-like. (107 aa)
nusANusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family. (188 aa)
rpoA2DNA-directed RNA polymerase, subunit A'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (395 aa)
AEH06468.1RNA polymerase Rpb1 domain 5; KEGG: mja:MJ_1043 DNA-directed RNA polymerase subunit A; PFAM: RNA polymerase Rpb1, domain 5; SMART: Hedgehog/intein hint, N-terminal. (492 aa)
AEH06469.1DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (888 aa)
AEH06470.1DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (611 aa)
AEH06471.1PFAM: RNA polymerase, beta subunit, protrusion; RNA polymerase Rpb2, domain 2; RNA polymerase Rpb2, domain 3; KEGG: mae:Maeo_0791 DNA-directed RNA polymerase subunit beta''; Belongs to the RNA polymerase beta chain family. (505 aa)
rpoHDNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (78 aa)
thiItRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (433 aa)
thi4Thiazole biosynthetic enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. (260 aa)
AEH06497.1S-methyl-5'-thioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (253 aa)
ribKRiboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. (133 aa)
ribB3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (227 aa)
AEH06500.1TIGRFAM: Riboflavin synthase, archaeal; KEGG: mmz:MmarC7_1180 riboflavin synthase; PFAM: 6,7-dimethyl-8-ribityllumazine synthase. (156 aa)
AEH06508.1Porphobilinogen synthase; KEGG: mja:MJ_0643 delta-aminolevulinic acid dehydratase; PFAM: Tetrapyrrole biosynthesis, porphobilinogen synthase; Belongs to the ALAD family. (324 aa)
cobDCobalamin biosynthesis protein cbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (328 aa)
mfnAL-tyrosine decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily. (390 aa)
AEH06539.1Radical SAM domain protein; KEGG: mae:Maeo_1026 biotin synthase; PFAM: Radical SAM; Biotin/thiamin synthesis-associated protein; SMART: Elongator protein 3/MiaB/NifB. (347 aa)
AEH06546.1SMART: DNA-directed DNA polymerase, family B; manually curated; KEGG: mae:Maeo_0653 DNA polymerase Pol2; TIGRFAM: DNA-directed DNA polymerase, family B, pol2; PFAM: DNA-directed DNA polymerase, family B, conserved region; DNA-directed DNA polymerase, family B, exonuclease domain. (810 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (226 aa)
AEH06552.1Transcription factor CBF/NF-Y/histone domain-containing protein; PFAM: Transcription factor CBF/NF-Y/archaeal histone; KEGG: mae:Maeo_1305 transcription factor CBF/NF-Y histone. (67 aa)
pdxSPyridoxal biosynthesis lyase pdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (299 aa)
purDPhosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; TIGRFAM: Phosphoribosylglycinamide synthetase; HAMAP: Phosphoribosylglycinamide synthetase; KEGG: mae:Maeo_1322 phosphoribosylamine--glycine ligase; Belongs to the GARS family. (443 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (311 aa)
purP5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate synthetase; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. (361 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. (151 aa)
AEH06590.1PyrE-like protein; KEGG: mmz:MmarC7_1077 orotate phosphoribosyltransferase-like protein; HAMAP: PyrE-like protein; PFAM: Phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (223 aa)
AEH06629.1PFAM: Cobalamin (vitamin B12) biosynthesis CbiX; KEGG: mmz:MmarC7_1164 sirohydrochlorin cobaltochelatase. (109 aa)
AEH06630.1KEGG: mae:Maeo_1381 sirohydrochlorin cobaltochelatase. (35 aa)
pyrKOxidoreductase FAD/NAD(P)-binding domain protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (261 aa)
AEH06642.1dUTP diphosphatase; KEGG: mae:Maeo_1372 deoxycytidine triphosphate deaminase, putative; manually curated. (159 aa)
AEH06651.1Precorrin-4 C11-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core; KEGG: mae:Maeo_1342 precorrin-4 C11-methyltransferase; PFAM: Tetrapyrrole methylase. (257 aa)
pyrBPFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; HAMAP: Aspartate carbamoyltransferase; KEGG: mae:Maeo_1339 aspartate carbamoyltransferase catalytic subunit. (303 aa)
cmkTIGRFAM: Cytidylate kinase, putative; HAMAP: Cytidylate kinase; KEGG: mae:Maeo_1127 cytidylate kinase. (179 aa)
adkAKEGG: mmx:MmarC6_1628 adenylate kinase; HAMAP: Adenylate kinase. (192 aa)
AEH06667.1PFAM: Sjogrens syndrome scleroderma autoantigen 1; KEGG: mae:Maeo_1131 hypothetical protein. (144 aa)
AEH06673.1KEGG: mae:Maeo_1134 hypothetical protein. (282 aa)
polCDNA polymerase II large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1696 aa)
mptAProtein of unknown function DUF198; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. (313 aa)
tfeTranscription factor E; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems [...] (199 aa)
tfbTranscription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (336 aa)
AEH06697.1Radical SAM domain protein; KEGG: mae:Maeo_1157 hypothetical protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB. (352 aa)
polBDNA-directed DNA polymerase; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. (595 aa)
priLDNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (361 aa)
AEH06717.1TIGRFAM: Pyridoxal phosphate-dependent transferase, archaea; KEGG: mae:Maeo_1169 L-seryl-tRNA selenium transferase. (362 aa)
cobSCobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (266 aa)
dcdDeoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (209 aa)
purCPFAM: SAICAR synthetase; TIGRFAM: SAICAR synthetase; HAMAP: Phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: mae:Maeo_0468 phosphoribosylaminoimidazole-succinocarboxamide synthase. (243 aa)
purSPhosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (82 aa)
hemLKEGG: mae:Maeo_1208 glutamate-1-semialdehyde aminotransferase; manually curated; TIGRFAM: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; PFAM: Aminotransferase class-III; HAMAP: Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (431 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (492 aa)
mptDProtein of unknown function DUF381; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family. (122 aa)
AEH06829.1Glucosamine-1-phosphate N-acetyltransferase; KEGG: mae:Maeo_0642 nucleotidyl transferase; PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide repeat. (408 aa)
AEH06846.1KEGG: mae:Maeo_0632 6-pyruvoyl tetrahydropterin synthase. (167 aa)
thyAThymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily. (223 aa)
AEH06877.1KEGG: mvu:Metvu_0107 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB. (302 aa)
AEH06912.1KEGG: mvn:Mevan_0815 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup. (85 aa)
AEH06913.1TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate; KEGG: mvn:Mevan_0816 pyruvate ferredoxin oxidoreductase subunit gamma; PFAM: Pyruvate/ketoisovalerate oxidoreductase. (176 aa)
AEH06941.1PFAM: RNA polymerase II, Rpb4; KEGG: mja:MJ_0039 hypothetical protein. (111 aa)
AEH06944.1KEGG: mmz:MmarC7_1088 siroheme synthase. (207 aa)
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (385 aa)
AEH06965.1Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA/pantothenate metabolism flavoprotein, C-terminal; Flavoprotein; manually curated; KEGG: mae:Maeo_1087 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; TIGRFAM: Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase. (411 aa)
AEH06971.1PFAM: RNA polymerase Rpb6; KEGG: mif:Metin_0693 RNA polymerase Rpb6. (56 aa)
rpoNDNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. (69 aa)
AEH06976.1PFAM: DNA-directed RNA polymerase, insert; DNA-directed RNA polymerase, dimerisation; KEGG: mae:Maeo_1098 RNA polymerase insert; SMART: DNA-directed RNA polymerase, RpoA/D/Rpb3-type. (197 aa)
mfnBUPF0264 protein; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P). (235 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (198 aa)
nadKInorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (654 aa)
purTPhosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (389 aa)
AEH07024.1PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; KEGG: mvo:Mvol_1600 NADH ubiquinone oxidoreductase 20 kDa subunit. (155 aa)
AEH07025.1NADH dehydrogenase (quinone); KEGG: mae:Maeo_0371 NADH-ubiquinone oxidoreductase chain 49kDa; PFAM: Nickel-dependent hydrogenase, large subunit; Belongs to the complex I 49 kDa subunit family. (378 aa)
ribLCytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (149 aa)
guaAAGMP synthase (glutamine-hydrolyzing) subunit A; Catalyzes the synthesis of GMP from XMP. (189 aa)
AEH07036.1KEGG: mae:Maeo_0873 putative molybdopterin-guanine dinucleotide biosynthesis protein MobB/FeS domain-containing protein protein; TIGRFAM: Molybdopterin-guanine dinucleotide biosynthesis MobB region; PFAM: Molybdopterin-guanine dinucleotide biosynthesis MobB region; Putative Fe-S cluster. (231 aa)
AEH07037.1Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; KEGG: mja:MJ_1522 cobalt-precorrin-6Y C(5)-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase, core; PFAM: Tetrapyrrole methylase. (205 aa)
AEH07043.1KEGG: mae:Maeo_1248 formate dehydrogenase family accessory protein FdhD; TIGRFAM: Formate dehydrogenase, subunit FdhD; PFAM: Formate dehydrogenase, subunit FdhD. (240 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (254 aa)
trpBTryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (389 aa)
trpFPhosphoribosylanthranilate isomerase; Manually curated; KEGG: mae:Maeo_1119 N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family. (208 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (452 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (335 aa)
AEH07053.1KEGG: mae:Maeo_1115 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase. (228 aa)
pyrCDihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (425 aa)
AEH07078.1ACT domain-containing protein; KEGG: mae:Maeo_0587 hypothetical protein; HAMAP: UPF0237 protein; PFAM: Amino acid-binding ACT; Belongs to the UPF0237 family. (90 aa)
nadAQuinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (309 aa)
AEH07137.1SMART: von Willebrand factor, type A; KEGG: mfs:MFS40622_1250 magnesium chelatase. (333 aa)
bioDDethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (213 aa)
AEH07146.1KEGG: mfs:MFS40622_1779 molybdenum cofactor synthesis domain protein; TIGRFAM: Molybdenum cofactor synthesis; PFAM: Molybdopterin binding; MoeA, N-terminal region, domain I/II; MoeA, C-terminal, domain IV. (380 aa)
dnaGUPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (512 aa)
hptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. (183 aa)
AEH07215.1UPF0284 protein; TIGRFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative; HAMAP: UPF0284 protein; KEGG: mae:Maeo_0615 hypothetical protein; PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like, core; Belongs to the UPF0284 family. (357 aa)
fae-hps3-hexulose-6-phosphate synthase; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the N-terminal section; belongs to the formaldehyde- activating enzyme family. (385 aa)
AEH07219.1KEGG: mae:Maeo_0894 AIR synthase related protein; manually curated; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein. (448 aa)
AEH07228.1Adenylyl cyclase CyaB; KEGG: mae:Maeo_0902 putative adenylyl cyclase CyaB; TIGRFAM: Adenylyl cyclase CyaB; PFAM: Adenylate cyclase. (191 aa)
moaCMolybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (153 aa)
cofGFO synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. (396 aa)
pyrDDihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. (304 aa)
AEH07241.1Nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (283 aa)
priSDNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] (360 aa)
ligDNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (580 aa)
AEH07248.1TIGRFAM: Uroporphyrin-III C-methyltransferase, C-terminal; KEGG: mvu:Metvu_1448 uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole methylase; Belongs to the precorrin methyltransferase family. (238 aa)
serSType-2 seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec); Belongs to the class-II aminoacyl-tRNA synthetase family. Type-2 seryl-tRNA synthetase subfamily. (518 aa)
AEH07262.1PFAM: AIR synthase related protein; AIR synthase related protein, C-terminal; KEGG: mvn:Mevan_0038 AIR synthase related protein. (293 aa)
bioAAdenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (485 aa)
AEH07306.1PFAM: Protein of unknown function DUF137; KEGG: mae:Maeo_0765 hypothetical protein. (272 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. (139 aa)
AEH07331.1O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. Belongs to the SepSecS family. (436 aa)
AEH07338.1PFAM: Molybdopterin biosynthesis MoaE; KEGG: mae:Maeo_0449 molybdopterin biosynthesis MoaE protein. (119 aa)
AEH07358.1Transcription factor CBF/NF-Y/histone domain-containing protein; KEGG: mae:Maeo_0659 transcription factor CBF/NF-Y histone; PFAM: Transcription factor CBF/NF-Y/archaeal histone; SMART: TATA box binding protein associated factor (TAF). (66 aa)
AEH07359.1TIGRFAM: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal; Riboflavin-specific deaminase, C-terminal; KEGG: mae:Maeo_0660 5-amino-6-(5-phosphoribosylamino)uracil reductase; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal. (225 aa)
AEH07360.1HAMAP: UPF0292 protein; PFAM: Toprim domain; KEGG: mae:Maeo_0661 hypothetical protein; SMART: Toprim domain, subgroup. (147 aa)
nadENH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (254 aa)
arfBCreatininase; Catalyzes the hydrolysis of the formamide of 2-amino-5- formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-monophosphate (FAPy) to form 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (APy). (227 aa)
AEH07366.1TIGRFAM: Acetate--CoA ligase; KEGG: mfe:Mefer_0312 acetate/CoA ligase; PFAM: AMP-dependent synthetase/ligase. (633 aa)
AEH07398.1Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (256 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (223 aa)
atpDV-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (213 aa)
atpBV-type ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (462 aa)
atpAV-type ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (586 aa)
atpFV-type ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. (99 aa)
atpCV-type ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane. (361 aa)
purQPhosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (226 aa)
AEH07449.1Precorrin-8X methylmutase CbiC/CobH; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; KEGG: mae:Maeo_0015 precorrin-8X methylmutase. (211 aa)
AEH07453.1KEGG: mae:Maeo_0986 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (448 aa)
mobAMolybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (224 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (134 aa)
AEH07479.1TIGRFAM: L-seryl-tRNA(Sec)kinase, archaea; KEGG: mae:Maeo_0491 chromatin associated protein KTI12. (256 aa)
AEH07481.1Adenylate kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (189 aa)
AEH07485.1Methanogenesis marker protein 2; KEGG: mae:Maeo_0496 AIR synthase related protein; TIGRFAM: Putative methanogenesis marker protein 2; PFAM: AIR synthase related protein; AIR synthase related protein, C-terminal. (324 aa)
queCexsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (233 aa)
purOIMP cyclohydrolase; Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP. (206 aa)
AEH07499.1PFAM: GHMP kinase; KEGG: mae:Maeo_0620 GHMP kinase. (311 aa)
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (297 aa)
cobQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (515 aa)
AEH07515.18-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (372 aa)
bioW6-carboxyhexanoate/CoA ligase; Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP. (233 aa)
carATIGRFAM: Carbamoyl phosphate synthase, small subunit; KEGG: mae:Maeo_0566 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; Belongs to the CarA family. (355 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (338 aa)
AEH07572.1KEGG: mae:Maeo_0320 archaeoflavoprotein AfpA; TIGRFAM: Archaeoflavoprotein AfpA; PFAM: Flavoprotein. (185 aa)
Your Current Organism:
Methanothermococcus okinawensis
NCBI taxonomy Id: 647113
Other names: M. okinawensis IH1, Methanothermococcus okinawensis DSM 14208, Methanothermococcus okinawensis IH1, Methanothermococcus okinawensis str. IH1, Methanothermococcus okinawensis strain IH1
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