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| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). (360 aa) |
| | AEH06006.1 | PFAM: Cobalamin (vitamin B12) biosynthesis CbiG, core; KEGG: mae:Maeo_0036 cobalamin (vitamin B12) biosynthesis CbiG protein. (340 aa) |
| | cbiD | cobalt-precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (381 aa) |
| | rps6e | KEGG: mae:Maeo_0200 30S ribosomal protein S6e; HAMAP: 30S ribosomal protein S6e; PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. (123 aa) |
| | tyrS | Tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (316 aa) |
| | rpoL | DNA-directed RNA polymerase subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. (101 aa) |
| | rpl1 | Ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (213 aa) |
| | rpl10 | Acidic ribosomal protein P0-like protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (338 aa) |
| | rpl12 | 50S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (101 aa) |
| | tbp | TATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (181 aa) |
| | AEH06036.1 | PFAM: Cytidylyltransferase; KEGG: mae:Maeo_0401 RfaE bifunctional protein. (63 aa) |
| | AEH06049.1 | KEGG: mtt:Ftrac_2377 methyltransferase type 11; manually curated; PFAM: Methyltransferase type 11. (329 aa) |
| | AEH06051.1 | KEGG: mif:Metin_1460 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. (644 aa) |
| | prf1 | Peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (419 aa) |
| | cbiA | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source. (458 aa) |
| | AEH06066.1 | PFAM: Radical SAM; KEGG: mvu:Metvu_0464 radical SAM domain protein. (206 aa) |
| | AEH06069.1 | KEGG: mae:Maeo_0512 radical SAM domain-containing protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB. (298 aa) |
| | AEH06073.1 | PFAM: Aspartate/homoserine dehydrogenase, NAD-binding; KEGG: mmq:MmarC5_0845 L-aspartate dehydrogenase. (134 aa) |
| | rpl31e | KEGG: mmz:MmarC7_1059 50S ribosomal protein L31e; HAMAP: 50S ribosomal protein L31e; PFAM: Ribosomal protein L31e; Belongs to the ribosomal protein L31e family. (83 aa) |
| | rpl18a | KEGG: mae:Maeo_0124 50S ribosomal protein LX; HAMAP: 50S ribosomal protein LX; PFAM: Ribosomal protein LX. (75 aa) |
| | thiC | Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (426 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (157 aa) |
| | tmk | PFAM: Thymidylate kinase-like; TIGRFAM: Thymidylate kinase; HAMAP: Thymidylate kinase; KEGG: mae:Maeo_0344 thymidylate kinase. (195 aa) |
| | AEH06123.1 | KEGG: mae:Maeo_0045 carbamoyl-phosphate synthase L chain ATP-binding; PFAM: MGS-like; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation; Carbamoyl phosphate synthetase, large subunit, ATP-binding. (603 aa) |
| | AEH06124.1 | KEGG: mae:Maeo_0044 carbamoyl-phosphate synthase L chain ATP-binding; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation. (479 aa) |
| | pyrI | Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase. (165 aa) |
| | AEH06128.1 | KEGG: mae:Maeo_0202 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00454; PFAM: Nucleotidyl transferase. (192 aa) |
| | AEH06139.1 | Transcription termination factor Tfs; SMART: Zinc finger, TFIIS-type; DNA-directed RNA polymerase, M/15kDa subunit; TIGRFAM: DNA-directed RNA polymerase, subunit M, archaeal; KEGG: mae:Maeo_0213 transcription termination factor Tfs; PFAM: Zinc finger, TFIIS-type; DNA-directed RNA polymerase, M/15kDa subunit; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (105 aa) |
| | lysS | PFAM: Lysyl-tRNA synthetase, class Ic; TIGRFAM: Lysyl-tRNA synthetase, class I; HAMAP: Lysyl-tRNA synthetase, class I, archaeal-type; KEGG: mae:Maeo_0215 lysyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (559 aa) |
| | AEH06144.1 | KEGG: mmz:MmarC7_0560 2-oxoglutarate ferredoxin oxidoreductase subunit gamma; PFAM: Pyruvate/ketoisovalerate oxidoreductase. (178 aa) |
| | AEH06148.1 | KEGG: mae:Maeo_0220 precorrin-6x reductase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobK/CbiJ, precorrin-6x reductase; PFAM: Cobalamin (vitamin B12) biosynthesis CobK/CbiJ, precorrin-6x reductase. (256 aa) |
| | leuS | TIGRFAM: Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic; KEGG: mae:Maeo_0233 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (976 aa) |
| | proS | Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (471 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (287 aa) |
| | AEH06188.1 | DNA binding protein, Tfx family; KEGG: mae:Maeo_0719 putative transcriptional regulator; TIGRFAM: DNA-binding protein Tfx, archaea; PFAM: RNA polymerase sigma-70 region 4. (134 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (734 aa) |
| | cbiT | cobalt-precorrin-6Y C(15)-methyltransferase (decarboxylating); Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7. (186 aa) |
| | AEH06208.1 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (185 aa) |
| | rps27ae | KEGG: mae:Maeo_0284 ribosomal protein S27a; HAMAP: 30S ribosomal protein S27ae; PFAM: Ribosomal protein S27a; Belongs to the eukaryotic ribosomal protein eS31 family. (58 aa) |
| | rps24e | KEGG: mvn:Mevan_1428 30S ribosomal protein S24e; HAMAP: 30S ribosomal protein S24e; PFAM: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. (103 aa) |
| | AEH06217.1 | UPF0218 protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (158 aa) |
| | AEH06219.1 | TIGRFAM: DNA-directed RNA polymerase; KEGG: mae:Maeo_0280 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7, N-terminal; Ribosomal protein S1, RNA binding domain. (189 aa) |
| | AEH06224.1 | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. (325 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (438 aa) |
| | hisS | ATP phosphoribosyltransferase regulatory subunit; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Anticodon-binding; TIGRFAM: Histidyl-tRNA synthetase, class IIa, subgroup; HAMAP: ATP phosphoribosyltransferase regulatory subunit; Histidyl-tRNA synthetase, class IIa, subgroup; KEGG: mae:Maeo_0030 histidyl-tRNA synthetase. (415 aa) |
| | rpl37e | 50S ribosomal protein L37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (62 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (456 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (336 aa) |
| | AEH06249.1 | Precorrin-2 C20-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobI/CbiL, precorrin-2 C20-methyltransferase, core; KEGG: mae:Maeo_0248 precorrin-2 C20-methyltransferase; PFAM: Tetrapyrrole methylase. (235 aa) |
| | eif2g | Translation initiation factor 2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (410 aa) |
| | AEH06256.1 | O-phospho-L-seryl-tRNA:Cys-tRNA synthase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family. (381 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (326 aa) |
| | rpl37ae | 50S ribosomal protein L37Ae; Binds to the 23S rRNA. (96 aa) |
| | AEH06264.1 | SMART: RNA polymerase Rbp10; KEGG: mae:Maeo_0178 RNA polymerase Rbp10. (46 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (546 aa) |
| | guaAB | GMP synthase (glutamine-hydrolyzing) subunit B; Catalyzes the synthesis of GMP from XMP. (310 aa) |
| | AEH06278.1 | PFAM: Cytidylyltransferase; TIGRFAM: Nicotinamide-nucleotide adenylyltransferase, archaeal type; Cytidyltransferase-related; HAMAP: Nicotinamide-nucleotide adenylyltransferase, archaeal type; KEGG: mae:Maeo_0254 nicotinamide-nucleotide adenylyltransferase. (170 aa) |
| | AEH06320.1 | KEGG: mae:Maeo_0515 beta-lactamase domain-containing protein. (268 aa) |
| | AEH06321.1 | Manually curated; TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic-like; KEGG: mae:Maeo_0516 anaerobic ribonucleoside-triphosphate reductase activating protein; PFAM: Radical SAM. (240 aa) |
| | mptE | Protein of unknown function DUF115; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. (251 aa) |
| | valS | Valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (885 aa) |
| | AEH06331.1 | PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; KEGG: mae:Maeo_0938 NADH ubiquinone oxidoreductase 20 kDa subunit. (251 aa) |
| | purM | TIGRFAM: Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: mmq:MmarC5_0337 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein. (350 aa) |
| | AEH06372.1 | precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; KEGG: mae:Maeo_0830 precorrin-3B C17-methyltransferase; PFAM: Tetrapyrrole methylase. (252 aa) |
| | queE | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (246 aa) |
| | AEH06378.1 | PFAM: Deoxyribonuclease/rho motif-related TRAM; KEGG: mae:Maeo_0835 deoxyribonuclease. (71 aa) |
| | AEH06381.1 | PFAM: 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; KEGG: mfs:MFS40622_0108 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase. (259 aa) |
| | rpl44e | Ribosomal protein L44E; Binds to the 23S rRNA. (93 aa) |
| | rps27e | KEGG: mae:Maeo_0702 30S ribosomal protein S27e; HAMAP: 30S ribosomal protein S27e; PFAM: Ribosomal protein S27e. (61 aa) |
| | AEH06429.1 | KEGG: mae:Maeo_0776 selenocysteine-specific translation elongation factor; TIGRFAM: Translation elongation factor, selenocysteine-specific; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2. (468 aa) |
| | AEH06459.1 | KEGG: fpl:Ferp_1321 rhodanese domain protein; PFAM: Rhodanese-like; SMART: Rhodanese-like. (107 aa) |
| | rps10 | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa) |
| | tuf | Translation elongation factor EF-1, subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (428 aa) |
| | fusA | Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...] (727 aa) |
| | rps7 | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (188 aa) |
| | rps12 | Ribosomal protein S23 (S12); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (147 aa) |
| | nusA | NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family. (188 aa) |
| | rpl30e | KEGG: mvo:Mvol_1025 ribosomal protein L7Ae/L30e/S12e/Gadd45; HAMAP: 50S ribosomal protein L30e; PFAM: Ribosomal protein L7Ae/L30e/S12e/Gadd45; Belongs to the eukaryotic ribosomal protein eL30 family. (98 aa) |
| | rpoA2 | DNA-directed RNA polymerase, subunit A'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (395 aa) |
| | AEH06468.1 | RNA polymerase Rpb1 domain 5; KEGG: mja:MJ_1043 DNA-directed RNA polymerase subunit A; PFAM: RNA polymerase Rpb1, domain 5; SMART: Hedgehog/intein hint, N-terminal. (492 aa) |
| | AEH06469.1 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (888 aa) |
| | AEH06470.1 | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (611 aa) |
| | AEH06471.1 | PFAM: RNA polymerase, beta subunit, protrusion; RNA polymerase Rpb2, domain 2; RNA polymerase Rpb2, domain 3; KEGG: mae:Maeo_0791 DNA-directed RNA polymerase subunit beta''; Belongs to the RNA polymerase beta chain family. (505 aa) |
| | rpoH | DNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (78 aa) |
| | thiI | tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (433 aa) |
| | thi4 | Thiazole biosynthetic enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. (260 aa) |
| | rps19p | Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (161 aa) |
| | rpl2 | Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (240 aa) |
| | rpl23 | Ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (86 aa) |
| | rpl4 | 50S ribosomal protein L4P; Forms part of the polypeptide exit tunnel. (256 aa) |
| | rpl3 | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (333 aa) |
| | AEH06497.1 | S-methyl-5'-thioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (253 aa) |
| | ribK | Riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. (133 aa) |
| | ribB | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (227 aa) |
| | AEH06500.1 | TIGRFAM: Riboflavin synthase, archaeal; KEGG: mmz:MmarC7_1180 riboflavin synthase; PFAM: 6,7-dimethyl-8-ribityllumazine synthase. (156 aa) |
| | AEH06508.1 | Porphobilinogen synthase; KEGG: mja:MJ_0643 delta-aminolevulinic acid dehydratase; PFAM: Tetrapyrrole biosynthesis, porphobilinogen synthase; Belongs to the ALAD family. (324 aa) |
| | eif5a | Translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (131 aa) |
| | cobD | Cobalamin biosynthesis protein cbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (328 aa) |
| | eif2a | Translation initiation factor 2 subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. (281 aa) |
| | gatA | Glutamyl-tRNA(Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (431 aa) |
| | mfnA | L-tyrosine decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily. (390 aa) |
| | rpl11 | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (160 aa) |
| | spt5 | NusG antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (146 aa) |
| | AEH06539.1 | Radical SAM domain protein; KEGG: mae:Maeo_1026 biotin synthase; PFAM: Radical SAM; Biotin/thiamin synthesis-associated protein; SMART: Elongator protein 3/MiaB/NifB. (347 aa) |
| | AEH06546.1 | SMART: DNA-directed DNA polymerase, family B; manually curated; KEGG: mae:Maeo_0653 DNA polymerase Pol2; TIGRFAM: DNA-directed DNA polymerase, family B, pol2; PFAM: DNA-directed DNA polymerase, family B, conserved region; DNA-directed DNA polymerase, family B, exonuclease domain. (810 aa) |
| | AEH06548.1 | KEGG: mae:Maeo_0651 putative ATPase RIL; PFAM: RNase L inhibitor RLI, possible metal-binding region; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; ABC transporter-like; SMART: ATPase, AAA+ type, core. (594 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (226 aa) |
| | AEH06552.1 | Transcription factor CBF/NF-Y/histone domain-containing protein; PFAM: Transcription factor CBF/NF-Y/archaeal histone; KEGG: mae:Maeo_1305 transcription factor CBF/NF-Y histone. (67 aa) |
| | pdxS | Pyridoxal biosynthesis lyase pdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (299 aa) |
| | purD | Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; TIGRFAM: Phosphoribosylglycinamide synthetase; HAMAP: Phosphoribosylglycinamide synthetase; KEGG: mae:Maeo_1322 phosphoribosylamine--glycine ligase; Belongs to the GARS family. (443 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (311 aa) |
| | purP | 5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate synthetase; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. (361 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. (151 aa) |
| | AEH06590.1 | PyrE-like protein; KEGG: mmz:MmarC7_1077 orotate phosphoribosyltransferase-like protein; HAMAP: PyrE-like protein; PFAM: Phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (223 aa) |
| | glyS | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). (576 aa) |
| | rps19e | Ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (148 aa) |
| | rpl39e | KEGG: mae:Maeo_1000 ribosomal protein L39e; HAMAP: 50S ribosomal protein L39e; PFAM: Ribosomal protein L39e; Belongs to the eukaryotic ribosomal protein eL39 family. (51 aa) |
| | AEH06629.1 | PFAM: Cobalamin (vitamin B12) biosynthesis CbiX; KEGG: mmz:MmarC7_1164 sirohydrochlorin cobaltochelatase. (109 aa) |
| | AEH06630.1 | KEGG: mae:Maeo_1381 sirohydrochlorin cobaltochelatase. (35 aa) |
| | pheT | Phenylalanyl-tRNA synthetase beta chain; PFAM: tRNA synthetase, B5; B3/B4 tRNA-binding domain; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic; HAMAP: Phenylalanyl-tRNA synthetase beta chain; KEGG: mae:Maeo_1377 phenylalanyl-tRNA synthetase subunit beta. (558 aa) |
| | cysS | TIGRFAM: Cysteinyl-tRNA synthetase, class Ia; KEGG: mae:Maeo_1376 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase, class Ia, N-terminal; Cysteinyl-tRNA synthetase, class Ia, DALR. (476 aa) |
| | pyrK | Oxidoreductase FAD/NAD(P)-binding domain protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (261 aa) |
| | AEH06642.1 | dUTP diphosphatase; KEGG: mae:Maeo_1372 deoxycytidine triphosphate deaminase, putative; manually curated. (159 aa) |
| | gatD | Glutamyl-tRNA(Gln) amidotransferase subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (431 aa) |
| | AEH06651.1 | Precorrin-4 C11-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core; KEGG: mae:Maeo_1342 precorrin-4 C11-methyltransferase; PFAM: Tetrapyrrole methylase. (257 aa) |
| | pyrB | PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; HAMAP: Aspartate carbamoyltransferase; KEGG: mae:Maeo_1339 aspartate carbamoyltransferase catalytic subunit. (303 aa) |
| | rps8e | TIGRFAM: Ribosomal protein S8e; HAMAP: 30S ribosomal protein S8e; KEGG: mae:Maeo_1338 30S ribosomal protein S8e; PFAM: Ribosomal protein S8e. (132 aa) |
| | rpl14e | HAMAP: 50S ribosomal protein L14e; KEGG: mvn:Mevan_1498 50S ribosomal protein L14e; Belongs to the eukaryotic ribosomal protein eL14 family. (77 aa) |
| | cmk | TIGRFAM: Cytidylate kinase, putative; HAMAP: Cytidylate kinase; KEGG: mae:Maeo_1127 cytidylate kinase. (179 aa) |
| | rpl34e | KEGG: mae:Maeo_1128 50S ribosomal protein L34e; HAMAP: 50S ribosomal protein L34e; PFAM: Ribosomal protein L34e; Belongs to the eukaryotic ribosomal protein eL34 family. (89 aa) |
| | adkA | KEGG: mmx:MmarC6_1628 adenylate kinase; HAMAP: Adenylate kinase. (192 aa) |
| | AEH06667.1 | PFAM: Sjogrens syndrome scleroderma autoantigen 1; KEGG: mae:Maeo_1131 hypothetical protein. (144 aa) |
| | gatE | Glutamyl-tRNA(Gln) amidotransferase subunit E; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (639 aa) |
| | AEH06673.1 | KEGG: mae:Maeo_1134 hypothetical protein. (282 aa) |
| | polC | DNA polymerase II large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1696 aa) |
| | mptA | Protein of unknown function DUF198; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. (313 aa) |
| | tfe | Transcription factor E; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems [...] (199 aa) |
| | tfb | Transcription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (336 aa) |
| | AEH06697.1 | Radical SAM domain protein; KEGG: mae:Maeo_1157 hypothetical protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB. (352 aa) |
| | polB | DNA-directed DNA polymerase; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. (595 aa) |
| | priL | DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (361 aa) |
| | AEH06717.1 | TIGRFAM: Pyridoxal phosphate-dependent transferase, archaea; KEGG: mae:Maeo_1169 L-seryl-tRNA selenium transferase. (362 aa) |
| | AEH06729.1 | KEGG: mae:Maeo_1179 HAD family hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, CTE7; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase-like hydrolase. (226 aa) |
| | cobS | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (266 aa) |
| | ef1b | Elongation factor 1-beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (89 aa) |
| | rpl22 | Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (153 aa) |
| | rps3 | Ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (219 aa) |
| | rpl29 | KEGG: mae:Maeo_1390 50S ribosomal protein L29P; TIGRFAM: Ribosomal protein L29; PFAM: Ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (70 aa) |
| | AEH06750.1 | TIGRFAM: Archaeal/bacterial translation initiation factor SUI1; HAMAP: Translation factor SUI1-like protein; KEGG: mae:Maeo_1391 translation initiation factor SUI1; PFAM: Translation initiation factor SUI1; Belongs to the SUI1 family. (102 aa) |
| | rps17 | Ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (122 aa) |
| | rpl14 | 50S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (132 aa) |
| | rpl24 | Ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit. (120 aa) |
| | rps4e | KEGG: mae:Maeo_1396 30S ribosomal protein S4e; HAMAP: 30S ribosomal protein S4e; PFAM: Ribosomal protein S4e, central; Ribosomal protein S4e, N-terminal; RNA-binding S4; Belongs to the eukaryotic ribosomal protein eS4 family. (247 aa) |
| | rpl5 | Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (182 aa) |
| | rps14 | Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles. (53 aa) |
| | rps8 | Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rpl6 | Ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (182 aa) |
| | rpl32e | KEGG: mae:Maeo_1401 50S ribosomal protein L32e; HAMAP: 50S ribosomal protein L32e; PFAM: Ribosomal protein L32e; Belongs to the eukaryotic ribosomal protein eL32 family. (153 aa) |
| | rpl19e | Ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (149 aa) |
| | rpl18 | Ribosomal protein L18P/L5E; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (194 aa) |
| | rps5 | Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy. (221 aa) |
| | rpl30 | KEGG: mae:Maeo_1405 50S ribosomal protein L30P; TIGRFAM: Ribosomal protein L30, archaeal; PFAM: Ribosomal protein L30p/L7e, conserved region. (154 aa) |
| | rpl15 | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (143 aa) |
| | dcd | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (209 aa) |
| | purC | PFAM: SAICAR synthetase; TIGRFAM: SAICAR synthetase; HAMAP: Phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: mae:Maeo_0468 phosphoribosylaminoimidazole-succinocarboxamide synthase. (243 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (82 aa) |
| | hemL | KEGG: mae:Maeo_1208 glutamate-1-semialdehyde aminotransferase; manually curated; TIGRFAM: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; PFAM: Aminotransferase class-III; HAMAP: Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (431 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (492 aa) |
| | thrS | TIGRFAM: Threonyl-tRNA synthetase, class IIa; KEGG: mae:Maeo_1189 threonyl-tRNA synthetase; PFAM: Threonyl-tRNA synthetase, editing region, archaea; Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Anticodon-binding; Belongs to the class-II aminoacyl-tRNA synthetase family. (631 aa) |
| | mptD | Protein of unknown function DUF381; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family. (122 aa) |
| | AEH06829.1 | Glucosamine-1-phosphate N-acetyltransferase; KEGG: mae:Maeo_0642 nucleotidyl transferase; PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide repeat. (408 aa) |
| | AEH06837.1 | KEGG: mfe:Mefer_1356 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB. (466 aa) |
| | AEH06846.1 | KEGG: mae:Maeo_0632 6-pyruvoyl tetrahydropterin synthase. (167 aa) |
| | thyA | Thymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily. (223 aa) |
| | AEH06874.1 | PFAM: Protein of unknown function DUF43; KEGG: mae:Maeo_0142 hypothetical protein. (406 aa) |
| | AEH06877.1 | KEGG: mvu:Metvu_0107 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB. (302 aa) |
| | AEH06912.1 | KEGG: mvn:Mevan_0815 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup. (85 aa) |
| | AEH06913.1 | TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate; KEGG: mvn:Mevan_0816 pyruvate ferredoxin oxidoreductase subunit gamma; PFAM: Pyruvate/ketoisovalerate oxidoreductase. (176 aa) |
| | rpl21e | KEGG: mvn:Mevan_1105 50S ribosomal protein L21e; HAMAP: 50S ribosomal protein L21e; PFAM: Ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. (98 aa) |
| | AEH06941.1 | PFAM: RNA polymerase II, Rpb4; KEGG: mja:MJ_0039 hypothetical protein. (111 aa) |
| | AEH06944.1 | KEGG: mmz:MmarC7_1088 siroheme synthase. (207 aa) |
| | hemA | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (385 aa) |
| | sepS | O-phosphoseryl-tRNA(Cys) synthetase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys). (539 aa) |
| | AEH06964.1 | PFAM: Translation elongation factor EFTu/EF1A, domain 2; KEGG: mae:Maeo_1086 elongation factor Tu domain-containing protein. (319 aa) |
| | AEH06965.1 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA/pantothenate metabolism flavoprotein, C-terminal; Flavoprotein; manually curated; KEGG: mae:Maeo_1087 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; TIGRFAM: Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase. (411 aa) |
| | AEH06971.1 | PFAM: RNA polymerase Rpb6; KEGG: mif:Metin_0693 RNA polymerase Rpb6. (56 aa) |
| | rpoN | DNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. (69 aa) |
| | rps9 | KEGG: mae:Maeo_1095 30S ribosomal protein S9P; TIGRFAM: Ribosomal protein S9, archaeal; PFAM: Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (134 aa) |
| | rpl13 | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (137 aa) |
| | rpl18e | KEGG: mae:Maeo_1097 50S ribosomal protein L18e; HAMAP: 50S ribosomal protein L18e; PFAM: Ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL18 family. (116 aa) |
| | AEH06976.1 | PFAM: DNA-directed RNA polymerase, insert; DNA-directed RNA polymerase, dimerisation; KEGG: mae:Maeo_1098 RNA polymerase insert; SMART: DNA-directed RNA polymerase, RpoA/D/Rpb3-type. (197 aa) |
| | rps11 | Ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (124 aa) |
| | rps4 | Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (177 aa) |
| | rps13 | Ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (168 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (198 aa) |
| | nadK | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (654 aa) |
| | purT | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (389 aa) |
| | pheS | PFAM: Phenylalanyl-tRNA synthetase alpha chain; manually curated; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, alpha subunit; KEGG: mae:Maeo_1292 phenylalanyl-tRNA synthetase subunit alpha; HAMAP: Phenylalanyl-tRNA synthetase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (506 aa) |
| | AEH07024.1 | PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; KEGG: mvo:Mvol_1600 NADH ubiquinone oxidoreductase 20 kDa subunit. (155 aa) |
| | AEH07025.1 | NADH dehydrogenase (quinone); KEGG: mae:Maeo_0371 NADH-ubiquinone oxidoreductase chain 49kDa; PFAM: Nickel-dependent hydrogenase, large subunit; Belongs to the complex I 49 kDa subunit family. (378 aa) |
| | ribL | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (149 aa) |
| | guaAA | GMP synthase (glutamine-hydrolyzing) subunit A; Catalyzes the synthesis of GMP from XMP. (189 aa) |
| | AEH07034.1 | KEGG: mae:Maeo_0871 small GTP-binding protein; TIGRFAM: Small GTP-binding protein; PFAM: TGS; GTP-binding protein, HSR1-related. (366 aa) |
| | AEH07037.1 | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; KEGG: mja:MJ_1522 cobalt-precorrin-6Y C(5)-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase, core; PFAM: Tetrapyrrole methylase. (205 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (254 aa) |
| | trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (389 aa) |
| | trpF | Phosphoribosylanthranilate isomerase; Manually curated; KEGG: mae:Maeo_1119 N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family. (208 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (452 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (335 aa) |
| | AEH07053.1 | KEGG: mae:Maeo_1115 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase. (228 aa) |
| | pyrC | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (425 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (556 aa) |
| | argS | TIGRFAM: Arginyl-tRNA synthetase, class Ic; HAMAP: Arginyl-tRNA synthetase, class Ic; KEGG: mae:Maeo_1102 arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (578 aa) |
| | AEH07063.1 | KEGG: mae:Maeo_0563 hypothetical protein; manually curated; PFAM: Fibronectin-binding A, N-terminal; Protein of unknown function DUF814. (684 aa) |
| | AEH07078.1 | ACT domain-containing protein; KEGG: mae:Maeo_0587 hypothetical protein; HAMAP: UPF0237 protein; PFAM: Amino acid-binding ACT; Belongs to the UPF0237 family. (90 aa) |
| | nadA | Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (309 aa) |
| | eif1a | Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (103 aa) |
| | speE | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family. (280 aa) |
| | speH | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. (117 aa) |
| | rps15 | PFAM: Ribosomal protein S13/S15, N-terminal; Ribosomal protein S15; KEGG: mae:Maeo_0606 30S ribosomal protein S15P. (171 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (905 aa) |
| | AEH07131.1 | TIGRFAM: universal PUA-domain-containing protein; Uncharacterised domain 2; PFAM: Pseudouridine synthase/archaeosine transglycosylase; KEGG: mae:Maeo_0751 putative RNA-binding protein; SMART: Pseudouridine synthase/archaeosine transglycosylase. (158 aa) |
| | AEH07137.1 | SMART: von Willebrand factor, type A; KEGG: mfs:MFS40622_1250 magnesium chelatase. (333 aa) |
| | bioD | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (213 aa) |
| | rpl24e | 50S ribosomal protein L24e; Binds to the 23S rRNA. (62 aa) |
| | rps28e | KEGG: mae:Maeo_0080 30S ribosomal protein S28e; HAMAP: 30S ribosomal protein S28e; PFAM: Ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family. (75 aa) |
| | rpl7ae | 50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (117 aa) |
| | dnaG | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (512 aa) |
| | rpl10e | TIGRFAM: Ribosomal protein L10e; HAMAP: 50S ribosomal protein L10e; KEGG: mae:Maeo_0013 50S ribosomal protein L10e; PFAM: Ribosomal protein L10e/L16; Belongs to the universal ribosomal protein uL16 family. (173 aa) |
| | eif2b | Translation initiation factor 2 subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (142 aa) |
| | rpl15e | KEGG: mmx:MmarC6_0655 50S ribosomal protein L15e; HAMAP: 50S ribosomal protein L15e; PFAM: Ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family. (194 aa) |
| | hpt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. (183 aa) |
| | AEH07215.1 | UPF0284 protein; TIGRFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative; HAMAP: UPF0284 protein; KEGG: mae:Maeo_0615 hypothetical protein; PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like, core; Belongs to the UPF0284 family. (357 aa) |
| | fae-hps | 3-hexulose-6-phosphate synthase; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the N-terminal section; belongs to the formaldehyde- activating enzyme family. (385 aa) |
| | AEH07219.1 | KEGG: mae:Maeo_0894 AIR synthase related protein; manually curated; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein. (448 aa) |
| | infB | Translation initiation factor aIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (602 aa) |
| | AEH07228.1 | Adenylyl cyclase CyaB; KEGG: mae:Maeo_0902 putative adenylyl cyclase CyaB; TIGRFAM: Adenylyl cyclase CyaB; PFAM: Adenylate cyclase. (191 aa) |
| | rps17e | KEGG: mmx:MmarC6_0316 30S ribosomal protein S17e; HAMAP: Ribosomal protein S17e; PFAM: Ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family. (63 aa) |
| | cofG | FO synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. (396 aa) |
| | pyrD | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. (304 aa) |
| | AEH07241.1 | Nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (283 aa) |
| | priS | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] (360 aa) |
| | lig | DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (580 aa) |
| | AEH07248.1 | TIGRFAM: Uroporphyrin-III C-methyltransferase, C-terminal; KEGG: mvu:Metvu_1448 uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole methylase; Belongs to the precorrin methyltransferase family. (238 aa) |
| | serS | Type-2 seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec); Belongs to the class-II aminoacyl-tRNA synthetase family. Type-2 seryl-tRNA synthetase subfamily. (518 aa) |
| | AEH07262.1 | PFAM: AIR synthase related protein; AIR synthase related protein, C-terminal; KEGG: mvn:Mevan_0038 AIR synthase related protein. (293 aa) |
| | rps3ae | KEGG: mae:Maeo_0757 30S ribosomal protein S3Ae; HAMAP: 30S ribosomal protein S3Ae; PFAM: Ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family. (234 aa) |
| | AEH07299.1 | KEGG: mae:Maeo_0758 hypothetical protein. (202 aa) |
| | rps2 | Ribosomal protein S2; KEGG: mae:Maeo_0759 30S ribosomal protein S2; TIGRFAM: Ribosomal protein S2, eukaryotic/archaeal; PFAM: Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (220 aa) |
| | bioA | Adenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (485 aa) |
| | AEH07306.1 | PFAM: Protein of unknown function DUF137; KEGG: mae:Maeo_0765 hypothetical protein. (272 aa) |
| | ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. (139 aa) |
| | AEH07331.1 | O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. Belongs to the SepSecS family. (436 aa) |
| | ileS | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1056 aa) |
| | AEH07358.1 | Transcription factor CBF/NF-Y/histone domain-containing protein; KEGG: mae:Maeo_0659 transcription factor CBF/NF-Y histone; PFAM: Transcription factor CBF/NF-Y/archaeal histone; SMART: TATA box binding protein associated factor (TAF). (66 aa) |
| | AEH07359.1 | TIGRFAM: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal; Riboflavin-specific deaminase, C-terminal; KEGG: mae:Maeo_0660 5-amino-6-(5-phosphoribosylamino)uracil reductase; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal. (225 aa) |
| | AEH07360.1 | HAMAP: UPF0292 protein; PFAM: Toprim domain; KEGG: mae:Maeo_0661 hypothetical protein; SMART: Toprim domain, subgroup. (147 aa) |
| | nadE | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (254 aa) |
| | arfB | Creatininase; Catalyzes the hydrolysis of the formamide of 2-amino-5- formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-monophosphate (FAPy) to form 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (APy). (227 aa) |
| | rpl40e | KEGG: mae:Maeo_0665 50S ribosomal protein L40e; HAMAP: 50S ribosomal protein L40e; PFAM: Ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. (47 aa) |
| | AEH07366.1 | TIGRFAM: Acetate--CoA ligase; KEGG: mfe:Mefer_0312 acetate/CoA ligase; PFAM: AMP-dependent synthetase/ligase. (633 aa) |
| | AEH07398.1 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (256 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (223 aa) |
| | atpD | V-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (213 aa) |
| | atpB | V-type ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (462 aa) |
| | atpA | V-type ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (586 aa) |
| | atpF | V-type ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. (99 aa) |
| | atpC | V-type ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane. (361 aa) |
| | gatB | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (467 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (226 aa) |
| | AEH07449.1 | Precorrin-8X methylmutase CbiC/CobH; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; KEGG: mae:Maeo_0015 precorrin-8X methylmutase. (211 aa) |
| | AEH07453.1 | KEGG: mae:Maeo_0986 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (448 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (134 aa) |
| | AEH07479.1 | TIGRFAM: L-seryl-tRNA(Sec)kinase, archaea; KEGG: mae:Maeo_0491 chromatin associated protein KTI12. (256 aa) |
| | AEH07481.1 | Adenylate kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (189 aa) |
| | AEH07485.1 | Methanogenesis marker protein 2; KEGG: mae:Maeo_0496 AIR synthase related protein; TIGRFAM: Putative methanogenesis marker protein 2; PFAM: AIR synthase related protein; AIR synthase related protein, C-terminal. (324 aa) |
| | queC | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (233 aa) |
| | purO | IMP cyclohydrolase; Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP. (206 aa) |
| | AEH07499.1 | PFAM: GHMP kinase; KEGG: mae:Maeo_0620 GHMP kinase. (311 aa) |
| | metG | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (691 aa) |
| | pth | Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. (116 aa) |
| | cobQ | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (515 aa) |
| | AEH07515.1 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (372 aa) |
| | bioW | 6-carboxyhexanoate/CoA ligase; Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP. (233 aa) |
| | pdxT | Glutamine amidotransferase subunit pdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (187 aa) |
| | carA | TIGRFAM: Carbamoyl phosphate synthase, small subunit; KEGG: mae:Maeo_0566 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; Belongs to the CarA family. (355 aa) |
| | thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (338 aa) |
| | AEH07572.1 | KEGG: mae:Maeo_0320 archaeoflavoprotein AfpA; TIGRFAM: Archaeoflavoprotein AfpA; PFAM: Flavoprotein. (185 aa) |
