STRINGSTRING
ADU28442.1 ADU28442.1 ecfA ecfA ADU28444.1 ADU28444.1 truA truA ADU28946.1 ADU28946.1 thiE thiE ADU29040.1 ADU29040.1 thiG thiG ADU29042.1 ADU29042.1 ADU29043.1 ADU29043.1 ADU29044.1 ADU29044.1 ADU29045.1 ADU29045.1 mqnD mqnD mqnB mqnB ADU29183.1 ADU29183.1 ADU29184.1 ADU29184.1 ADU29185.1 ADU29185.1 ADU29186.1 ADU29186.1 ADU29187.1 ADU29187.1 ADU29188.1 ADU29188.1 ADU29189.1 ADU29189.1 ecfA-2 ecfA-2 ecfA-3 ecfA-3 ecfT ecfT ADU29193.1 ADU29193.1 ADU30126.1 ADU30126.1 ADU30127.1 ADU30127.1 menG menG ADU30129.1 ADU30129.1 ubiX ubiX mqnA mqnA ADU30132.1 ADU30132.1 thiM thiM ADU31086.1 ADU31086.1 ADU31108.1 ADU31108.1 ADU31109.1 ADU31109.1 ADU31110.1 ADU31110.1 ADU31111.1 ADU31111.1 ADU31112.1 ADU31112.1 mqnC mqnC ADU31634.1 ADU31634.1 ADU31644.1 ADU31644.1 mqnE mqnE thiC thiC ADU32452.1 ADU32452.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADU28442.1KEGG: ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase. (279 aa)
ecfAABC transporter related protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (291 aa)
ADU28444.1PFAM: cobalt transport protein; KEGG: cobalt transport protein. (266 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (260 aa)
ADU28946.1UbiD family decarboxylase; KEGG: bha:BH3930 hypothetical protein; TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein; Belongs to the UbiD family. (609 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (216 aa)
ADU29040.1KEGG: gwc:GWCH70_1938 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. (280 aa)
thiGThiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (255 aa)
ADU29042.1KEGG: dae:Dtox_1681 thiazole biosynthesis protein ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein. (367 aa)
ADU29043.1PFAM: thiamine monophosphate synthase; KEGG: afl:Aflv_2316 transcriptional regulator TenI. (199 aa)
ADU29044.1KEGG: bcy:Bcer98_0618 sulfur carrier protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. (66 aa)
ADU29045.1PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: bcg:BCG9842_B4541 thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein. (339 aa)
mqnDProtein of unknown function DUF191; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (281 aa)
mqnBFutalosine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). (218 aa)
ADU29183.1KEGG: oih:OB0383 hypothetical protein. (213 aa)
ADU29184.1KEGG: gym:GYMC10_2649 transcriptional regulator, MerR family; PFAM: regulatory protein MerR; SMART: regulatory protein MerR. (247 aa)
ADU29185.1PFAM: Polyprenyl synthetase; KEGG: lmc:Lm4b_02608 heptaprenyl diphosphate synthase component II; Belongs to the FPP/GGPP synthase family. (326 aa)
ADU29186.1PFAM: Heptaprenyl diphosphate synthase component I; KEGG: lsg:lse_2545 hypothetical protein. (178 aa)
ADU29187.1PFAM: protein of unknown function DUF1312; KEGG: lmy:LM5923_0221 hypothetical protein. (136 aa)
ADU29188.1PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: lmh:LMHCC_2896 pyridine nucleotide-disulfide oxidoreductase family protein. (659 aa)
ADU29189.1ApbE family lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. (354 aa)
ecfA-2ABC transporter related protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (270 aa)
ecfA-3ABC transporter related protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (283 aa)
ecfTCobalt transport protein; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (264 aa)
ADU29193.1KEGG: vvi:100260954 hypothetical protein LOC100260954. (64 aa)
ADU30126.1PFAM: tryptophan RNA-binding attenuator protein; KEGG: tryptophan RNA-binding attenuator protein. (73 aa)
ADU30127.1KEGG: bpf:BpOF4_15395 heptaprenyl diphosphate synthase component I (spore germination protein C1). (271 aa)
menG2-heptaprenyl-1,4-naphthoquinone methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (234 aa)
ADU30129.1KEGG: 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; Belongs to the UbiA prenyltransferase family. (290 aa)
ubiX3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (199 aa)
mqnAProtein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (285 aa)
ADU30132.1KEGG: heptaprenyl diphosphate synthase component II; TIGRFAM: heptaprenyl diphosphate synthase component II; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (323 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (269 aa)
ADU31086.1KEGG: gym:GYMC10_0625 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; Belongs to the UbiA prenyltransferase family. (297 aa)
ADU31108.1KEGG: hypothetical protein. (230 aa)
ADU31109.1KEGG: bwe:BcerKBAB4_3041 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (546 aa)
ADU31110.1PFAM: cobalt transport protein; KEGG: bai:BAA_3400 ABC transporter, permease protein. (292 aa)
ADU31111.1KEGG: bcy:Bcer98_2116 hypothetical protein. (275 aa)
ADU31112.1KEGG: hypothetical protein; TIGRFAM: LPXTG-motif cell wall anchor domain protein; PFAM: Gram-positive anchor. (433 aa)
mqnCRadical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (369 aa)
ADU31634.1PFAM: BioY protein; KEGG: bpf:BpOF4_04690 putative biotin biosynthesis protein BioY. (201 aa)
ADU31644.1KEGG: bpf:BpOF4_04810 NADH dehydrogenase, NDH-2A; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (403 aa)
mqnERadical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (364 aa)
thiCThiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (597 aa)
ADU32452.1Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. (224 aa)
Your Current Organism:
Bacillus cellulosilyticus
NCBI taxonomy Id: 649639
Other names: B. cellulosilyticus DSM 2522, Bacillus cellulosilyticus DSM 2522, Bacillus cellulosilyticus str. DSM 2522, Bacillus cellulosilyticus strain DSM 2522, Bacillus sp. (STRAIN N-4), Bacillus sp. ATCC 21833, Bacillus sp. N-4
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