STRINGSTRING
CUN36352.1 CUN36352.1 amiB amiB murF murF yceG yceG ddl ddl cca cca murAB murAB CUN56651.1 CUN56651.1 maf maf swrC swrC CUN78152.1 CUN78152.1 ruvA ruvA ruvB ruvB yhbU_1 yhbU_1 ftsW_1 ftsW_1 pbpA_1 pbpA_1 CUN78481.1 CUN78481.1 dacC dacC mraY_1 mraY_1 CUO01043.1 CUO01043.1 miaB_1 miaB_1 mutS mutS mutL mutL miaA miaA metB_1 metB_1 CUO01392.1 CUO01392.1 mreB_2 mreB_2 CUO01488.1 CUO01488.1 CUO01534.1 CUO01534.1 pbpA_2 pbpA_2 minC minC minD minD minE minE ftsW_2 ftsW_2 mgsA mgsA dacB_3 dacB_3 CUO01931.1 CUO01931.1 CUO01979.1 CUO01979.1 CUO02024.1 CUO02024.1 sepF sepF CUO02150.1 CUO02150.1 divIVA divIVA lspA lspA rluD rluD proC proC cwlC_2 cwlC_2 mrcA mrcA murB murB murC murC pbpD pbpD uppP uppP murE murE murG murG ftsZ ftsZ CUO51988.1 CUO51988.1 ftsW_3 ftsW_3 murD murD mraY_2 mraY_2 penA_2 penA_2 penA_3 penA_3 CUO52214.1 CUO52214.1 rsmH_2 rsmH_2 mraZ mraZ lgt lgt engD engD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CUN36352.1Protein required for the initiation of cell division. (89 aa)
amiBN-acetylmuramoyl-L-alanine amidase AmiB precursor. (227 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (452 aa)
yceGPutative aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (320 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (353 aa)
ccaCCA-adding enzyme. (448 aa)
murABUDP-N-acetylglucosamine 1-carboxyvinyltransferase 2; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (431 aa)
CUN56651.1Uncharacterised protein. (261 aa)
mafSeptum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (183 aa)
swrCSwarming motility protein SwrC; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1225 aa)
CUN78152.1Predicted exonuclease. (310 aa)
ruvAHolliday junction ATP-dependent DNA helicase RuvA. (201 aa)
ruvBHolliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (334 aa)
yhbU_1Uncharacterized protease yhbU precursor. (793 aa)
ftsW_1Cell division protein FtsW; Belongs to the SEDS family. (458 aa)
pbpA_1Penicillin-binding protein A. (417 aa)
CUN78481.1RNA pyrophosphohydrolase. (149 aa)
dacCD-alanyl-D-alanine carboxypeptidase dacC precursor; Belongs to the peptidase S11 family. (399 aa)
mraY_1Phospho-N-acetylmuramoyl-pentapeptide- transferase. (320 aa)
CUO01043.1Na/Pi-cotransporter II-related protein. (560 aa)
miaB_1(Dimethylallyl)adenosine tRNA methylthiotransferase MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (470 aa)
mutSDNA mismatch repair protein mutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (875 aa)
mutLDNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (660 aa)
miaAtRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (320 aa)
metB_1Cystathionine gamma-synthase. (431 aa)
CUO01392.1DNA repair protein RadC; Belongs to the UPF0758 family. (232 aa)
mreB_2Rod shape-determining protein MreB. (318 aa)
CUO01488.1Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. (288 aa)
CUO01534.1Rod shape-determining protein MreD. (171 aa)
pbpA_2Penicillin-binding protein A. (971 aa)
minCSeptum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (246 aa)
minDCell division inhibitor MinD. (261 aa)
minECell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. (86 aa)
ftsW_2Cell division protein FtsW; Belongs to the SEDS family. (371 aa)
mgsAMethylglyoxal synthase. (130 aa)
dacB_3D-alanyl-D-alanine carboxypeptidase dacB precursor; Belongs to the peptidase S11 family. (312 aa)
CUO01931.1Coproporphyrinogen III oxidase. (314 aa)
CUO01979.1Putative membrane fusion protein. (459 aa)
CUO02024.1Predicted enzyme with a TIM-barrel fold; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (231 aa)
sepFCell division protein SepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (182 aa)
CUO02150.1Photosystem II S4 domain protein. (251 aa)
divIVAMinicell-associated protein DivIVA. (194 aa)
lspALipoprotein signal peptidase. (169 aa)
rluDRibosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (305 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (272 aa)
cwlC_2Sporulation-specific N-acetylmuramoyl-L-alanine amidase. (253 aa)
mrcAPenicillin-binding protein 1A. (845 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (302 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (461 aa)
pbpDPenicillin-binding protein 4 precursor. (735 aa)
uppPUndecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (275 aa)
murEUDP-N-acetylmuramoyl-L-alanyl-D-glutamate-- 2%2C6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (485 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (359 aa)
ftsZCell division protein FtsZ. (392 aa)
CUO51988.1Uncharacterised protein. (256 aa)
ftsW_3Cell division protein FtsW. (374 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (454 aa)
mraY_2Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (323 aa)
penA_2Penicillin-binding protein 2. (578 aa)
penA_3Penicillin-binding protein 2. (605 aa)
CUO52214.1Protein required for the initiation of cell division. (161 aa)
rsmH_2Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (311 aa)
mraZCell division protein MraZ; Belongs to the MraZ family. (146 aa)
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (298 aa)
engDGTP-dependent nucleic acid-binding protein engD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (363 aa)
Your Current Organism:
Anaerostipes hadrus
NCBI taxonomy Id: 649756
Other names: A. hadrus, ATCC 29173, Anaerostipes sp. 5/1/63FAA, Clostridiales bacterium SSC/2, DSM 3319, Eubacterium hadrum, JCM 9980, VP 82-52, VPI B2-52, butyrate-producing bacterium SS2/1, butyrate-producing bacterium SSC/2
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