STRINGSTRING
pfp_2 pfp_2 ptsG_1 ptsG_1 CUO03866.1 CUO03866.1 iolC iolC sacX sacX CUN99706.1 CUN99706.1 pyk_2 pyk_2 phoR_4 phoR_4 arcB_2 arcB_2 rpfC_1 rpfC_1 ribF ribF CUN93663.1 CUN93663.1 ppnK ppnK senX3 senX3 thiM thiM CUN78875.1 CUN78875.1 srlE_1 srlE_1 srlA_1 srlA_1 licR_4 licR_4 galK galK yehU yehU xylB_2 xylB_2 manP_2 manP_2 bglF_1 bglF_1 CUN69059.1 CUN69059.1 manX_5 manX_5 lsrK lsrK gmuC gmuC ulaB ulaB ulaC ulaC glpK_2 glpK_2 divL divL treB treB prkC_1 prkC_1 ywqD_2 ywqD_2 ywqD_1 ywqD_1 CUN57929.1 CUN57929.1 cpsD cpsD cap8A cap8A manY_1 manY_1 manX_3 manX_3 nreB nreB spoIIAB spoIIAB glpK_1 glpK_1 barA_1 barA_1 aroK_1 aroK_1 phoR_3 phoR_3 phoR_1 phoR_1 yycG yycG dhaL_1 dhaL_1 dhaK_1 dhaK_1 dhaK_2 dhaK_2 gatB_1 gatB_1 glxK glxK levE levE bvgS bvgS fruA_3 fruA_3 coaX coaX pfkA pfkA gatB_2 gatB_2 xylB_3 xylB_3 coaE coaE phoR_6 phoR_6 licR_7 licR_7 udk_1 udk_1 dagK dagK CUO54315.1 CUO54315.1 srlE_3 srlE_3 srlE_2 srlE_2 CUO51343.1 CUO51343.1 dhaL_2 dhaL_2 lacC_2 lacC_2 CUO47680.1 CUO47680.1 prkC_2 prkC_2 luxQ luxQ udk_2 udk_2 licR_2 licR_2 phoR_2 phoR_2 xylB_1 xylB_1 CUN44220.1 CUN44220.1 coaA coaA kdpD_1 kdpD_1 fruA_1 fruA_1 manP_1 manP_1 fruA_2 fruA_2 licR_3 licR_3 pyk_1 pyk_1 pknB pknB pfp_1 pfp_1 walK walK rpfC_2 rpfC_2 ispE ispE manP_3 manP_3 CUO18479.1 CUO18479.1 kdpD_2 kdpD_2 licR_5 licR_5 gatB_4 gatB_4 lacC_1 lacC_1 hprK hprK mtlA_1 mtlA_1 pdxK pdxK phoR_5 phoR_5 ptsG_2 ptsG_2 manY_2 manY_2 manX_6 manX_6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pfp_2Pyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (406 aa)
ptsG_1EIICBA-Glc. (488 aa)
CUO03866.1SynChlorMet cassette protein ScmD. (89 aa)
iolC5-dehydro-2-deoxygluconokinase. (323 aa)
sacXPTS system sac EIIBC component. (642 aa)
CUN99706.1Dihydroxyacetone kinase. (560 aa)
pyk_2Pyruvate kinase; Belongs to the pyruvate kinase family. (480 aa)
phoR_4Alkaline phosphatase synthesis sensor protein phoR. (492 aa)
arcB_2Aerobic respiration control sensor protein ArcB. (169 aa)
rpfC_1Sensory/regulatory protein RpfC. (1088 aa)
ribFRiboflavin biosynthesis protein ribF; Belongs to the ribF family. (320 aa)
CUN93663.1Hpt domain. (116 aa)
ppnKProbable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (286 aa)
senX3Signal-transduction histidine kinase senX3. (466 aa)
thiMHydroxyethylthiazole kinase. (275 aa)
CUN78875.1PTS system glucitol/sorbitol-specific transporter subunit IIA. (117 aa)
srlE_1Glucitol/sorbitol-specific phosphotransferase enzyme IIB component. (337 aa)
srlA_1PTS system glucitol/sorbitol-specific EIIC component. (180 aa)
licR_4Probable licABCH operon regulator. (640 aa)
galKGalactokinase; Belongs to the GHMP kinase family. (427 aa)
yehUProbable sensor-like histidine kinase YehU. (488 aa)
xylB_2Xylulose kinase. (530 aa)
manP_2EIIBCA-Man. (116 aa)
bglF_1EIIBCA-Bgl. (627 aa)
CUN69059.1PTS system glucitol/sorbitol-specific transporter subunit IIA. (122 aa)
manX_5EIIAB-Man. (161 aa)
lsrKAutoinducer 2 kinase LsrK. (521 aa)
gmuCPTS system N%2CN'-diacetylchitobiose-specific transporter subunit IIC; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (133 aa)
ulaBAscorbate-specific phosphotransferase enzyme IIB component. (97 aa)
ulaCAscorbate-specific phosphotransferase enzyme IIA component. (149 aa)
glpK_2Glycerol kinase. (490 aa)
divLSensor protein divL. (713 aa)
treBEIIBC-Tre. (635 aa)
prkC_1Serine/threonine-protein kinase PrkC. (616 aa)
ywqD_2Tyrosine-protein kinase YwqD. (472 aa)
ywqD_1Tyrosine-protein kinase YwqD. (526 aa)
CUN57929.1Uncharacterised protein. (284 aa)
cpsDTyrosine-protein kinase CpsD. (235 aa)
cap8ACapsular polysaccharide type 8 biosynthesis protein cap8A. (206 aa)
manY_1PTS system mannose-specific EIIC component. (284 aa)
manX_3EIIAB-Man. (165 aa)
nreBOxygen sensor histidine kinase nreB. (440 aa)
spoIIABAnti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. (142 aa)
glpK_1Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (497 aa)
barA_1Signal transduction histidine-protein kinase BarA. (236 aa)
aroK_1Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (167 aa)
phoR_3Alkaline phosphatase synthesis sensor protein phoR. (454 aa)
phoR_1Alkaline phosphatase synthesis sensor protein phoR. (449 aa)
yycGSensor histidine kinase YycG. (495 aa)
dhaL_1PTS-dependent dihydroxyacetone kinase%2C ADP-binding subunit dhaL. (206 aa)
dhaK_1PTS-dependent dihydroxyacetone kinase%2C dihydroxyacetone-binding subunit dhaK. (336 aa)
dhaK_2PTS-dependent dihydroxyacetone kinase%2C dihydroxyacetone-binding subunit dhaK. (332 aa)
gatB_1Galactitol-specific phosphotransferase enzyme IIB component. (92 aa)
glxKGlycerate kinase; Belongs to the glycerate kinase type-1 family. (263 aa)
levEFructose-specific phosphotransferase enzyme IIB component. (157 aa)
bvgSVirulence sensor protein BvgS precursor. (641 aa)
fruA_3EIIABC-Fru. (653 aa)
coaXType III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (254 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (329 aa)
gatB_2Galactitol-specific phosphotransferase enzyme IIB component. (94 aa)
xylB_3Xylulose kinase. (485 aa)
coaEDephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (195 aa)
phoR_6Phosphate regulon sensor protein phoR. (454 aa)
licR_7Probable licABCH operon regulator. (694 aa)
udk_1Uridine kinase. (209 aa)
dagKDiacylglycerol kinase. (305 aa)
CUO54315.1PTS system glucitol/sorbitol-specific transporter subunit IIA. (122 aa)
srlE_3Glucitol/sorbitol-specific phosphotransferase enzyme IIB component. (337 aa)
srlE_2Glucitol/sorbitol-specific phosphotransferase enzyme IIB component. (338 aa)
CUO51343.1PTS system glucitol/sorbitol-specific transporter subunit IIA. (122 aa)
dhaL_2PTS-dependent dihydroxyacetone kinase%2C ADP-binding subunit dhaL. (213 aa)
lacC_2Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (301 aa)
CUO47680.1Predicted membrane protein%2C putative toxin regulator. (350 aa)
prkC_2Serine/threonine-protein kinase PrkC. (484 aa)
luxQAutoinducer 2 sensor kinase/phosphatase luxQ. (667 aa)
udk_2Uridine kinase. (551 aa)
licR_2Probable licABCH operon regulator. (678 aa)
phoR_2Alkaline phosphatase synthesis sensor protein phoR. (364 aa)
xylB_1Xylulose kinase. (489 aa)
CUN44220.1PTS system mannitol-specific transporter subunit IICBA. (62 aa)
coaAPantothenate kinase. (248 aa)
kdpD_1Sensor protein KdpD. (383 aa)
fruA_1EIIBC-Fru. (362 aa)
manP_1EIIBCA-Man. (103 aa)
fruA_2EIIABC-Fru. (149 aa)
licR_3Probable licABCH operon regulator. (656 aa)
pyk_1Pyruvate kinase; Belongs to the pyruvate kinase family. (324 aa)
pknBSerine/threonine-protein kinase pknB. (366 aa)
pfp_1Pyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (357 aa)
walKSensor protein kinase walK. (394 aa)
rpfC_2Sensory/regulatory protein RpfC. (713 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (288 aa)
manP_3EIIBCA-Man. (108 aa)
CUO18479.1Uncharacterised protein. (122 aa)
kdpD_2Sensor protein KdpD. (658 aa)
licR_5Probable licABCH operon regulator. (699 aa)
gatB_4Galactitol-specific phosphotransferase enzyme IIB component. (99 aa)
lacC_1Tagatose-6-phosphate kinase. (311 aa)
hprKHPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon [...] (311 aa)
mtlA_1EIICBA-Mtl. (595 aa)
pdxKPyridoxine kinase; Belongs to the pyridoxine kinase family. (290 aa)
phoR_5Alkaline phosphatase synthesis sensor protein phoR. (475 aa)
ptsG_2EIICBA-Glc. (696 aa)
manY_2PTS system mannose-specific EIIC component. (265 aa)
manX_6EIIAB-Man. (327 aa)
Your Current Organism:
Anaerostipes hadrus
NCBI taxonomy Id: 649756
Other names: A. hadrus, ATCC 29173, Anaerostipes sp. 5/1/63FAA, Clostridiales bacterium SSC/2, DSM 3319, Eubacterium hadrum, JCM 9980, VP 82-52, VPI B2-52, butyrate-producing bacterium SS2/1, butyrate-producing bacterium SSC/2
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