STRINGSTRING
pyrC pyrC sigE sigE CUN35042.1 CUN35042.1 pncB2 pncB2 coaBC coaBC atpC_1 atpC_1 atpD_1 atpD_1 atpG_1 atpG_1 atpA_1 atpA_1 atpH_1 atpH_1 atpF_1 atpF_1 atpE_1 atpE_1 atpB_1 atpB_1 atpC_2 atpC_2 atpD_2 atpD_2 atpG_2 atpG_2 atpA_2 atpA_2 atpH_2 atpH_2 atpF_2 atpF_2 atpE_2 atpE_2 atpB_2 atpB_2 rpoC rpoC rpoB rpoB hpt hpt coaX coaX dnaE dnaE nusG nusG queF queF polC_1 polC_1 nadC nadC nadA nadA coaA coaA guaA guaA murAB murAB dnaX_1 dnaX_1 sigF_1 sigF_1 rho rho nadE nadE accC accC priA priA purF purF purB purB CUN61491.1 CUN61491.1 purC purC CUN65506.1 CUN65506.1 purL purL nrdG nrdG pyrK_1 pyrK_1 guaB guaB CUN73245.1 CUN73245.1 carA carA carB_1 carB_1 CUN73521.1 CUN73521.1 purH purH CUN76789.1 CUN76789.1 purA purA nadD nadD CUN81243.1 CUN81243.1 CUN84086.1 CUN84086.1 CUN85112.1 CUN85112.1 pyrB pyrB pyrI pyrI relA relA dinB_1 dinB_1 nusB nusB ppnK ppnK CUN93033.1 CUN93033.1 pyrH pyrH polC_2 polC_2 nusA nusA ribF ribF CUN94560.1 CUN94560.1 coaD coaD ackA ackA spoT spoT ywaC_1 ywaC_1 rfbD rfbD rmlC rmlC sigH sigH CUO06410.1 CUO06410.1 pyrF pyrF pyrK_2 pyrK_2 pyrD pyrD pyrE pyrE purE purE purM purM purN purN purD purD sigF_2 sigF_2 queA queA cmk cmk folD folD yfaY yfaY pflA_1-2 pflA_1-2 rpoA rpoA adk adk accA accA accD accD cfiB_2 cfiB_2 xpt xpt carB_2 carB_2 atpD_3 atpD_3 ntpB ntpB atpA_3 atpA_3 CUO21584.1 CUO21584.1 CUO21660.1 CUO21660.1 dnaC_1 dnaC_1 prs prs ywaC_2 ywaC_2 dnaX_2 dnaX_2 tmk tmk CUO31173.1 CUO31173.1 udk_1 udk_1 rpoE rpoE dinB_2 dinB_2 glmU glmU sigK sigK CUO40488.1 CUO40488.1 coaE coaE polA polA queC queC queE queE CUO41260.1 CUO41260.1 udk_2 udk_2 rpoD_1 rpoD_1 dnaG dnaG rpoD_2 rpoD_2 rpoZ rpoZ gmk gmk yjbM yjbM CUO43568.1 CUO43568.1 tgt tgt CUO46151.1 CUO46151.1 thyA1 thyA1 CUO47756.1 CUO47756.1 dut dut serS serS dnaN dnaN CUO50160.1 CUO50160.1 pyrG pyrG
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proteins of unknown 3D structure
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pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (420 aa)
sigERNA polymerase sigma-35 factor precursor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (238 aa)
CUN35042.1DNA integrity scanning protein DisA. (290 aa)
pncB2Nicotinate phosphoribosyltransferase 2; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (484 aa)
coaBCDNA/pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (396 aa)
atpC_1F-ATPase epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (134 aa)
atpD_1ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (467 aa)
atpG_1Na(+)-translocating ATPase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (286 aa)
atpA_1ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (502 aa)
atpH_1F-type ATPase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (181 aa)
atpF_1F-type ATPase subunit b. (173 aa)
atpE_1Lipid-binding protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (87 aa)
atpB_1F-ATPase subunit 6; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (243 aa)
atpC_2F-ATPase epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (137 aa)
atpD_2ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (462 aa)
atpG_2Na(+)-translocating ATPase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (289 aa)
atpA_2ATP synthase subunit alpha. (499 aa)
atpH_2F-type ATPase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (167 aa)
atpF_2F-type ATPase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (160 aa)
atpE_2Lipid-binding protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (72 aa)
atpB_2F-ATPase subunit 6; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (256 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1199 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1265 aa)
hptHypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (173 aa)
coaXType III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (254 aa)
dnaEDNA polymerase III subunit alpha. (1151 aa)
nusGTranscription antitermination protein nusG; Participates in transcription elongation, termination and antitermination. (181 aa)
queFNADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (165 aa)
polC_1DNA polymerase III polC-type. (235 aa)
nadCProbable nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family. (285 aa)
nadAQuinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (302 aa)
coaAPantothenate kinase. (248 aa)
guaAGMP synthase [glutamine-hydrolyzing]. (515 aa)
murABUDP-N-acetylglucosamine 1-carboxyvinyltransferase 2; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (431 aa)
dnaX_1DNA polymerase III subunit tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (535 aa)
sigF_1Stage II sporulation protein AC; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (241 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (449 aa)
nadEGlutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (632 aa)
accCBiotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (742 aa)
purFAmidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (475 aa)
purBAdenylosuccinate lyase. (476 aa)
CUN61491.1Region found in RelA / SpoT proteins. (291 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (288 aa)
CUN65506.1Predicted ATPase. (461 aa)
purLPhosphoribosylformylglycinamidine synthase 2. (1251 aa)
nrdGAnaerobic ribonucleotide reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (162 aa)
pyrK_1Dihydrdoorotate oxidase B%2C electron transfer subunit. (273 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (483 aa)
CUN73245.1Uncharacterized BCR%2C COG1636. (213 aa)
carACarbamoyl-phosphate synthase small chain; Belongs to the CarA family. (359 aa)
carB_1Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1066 aa)
CUN73521.1IMP cyclohydrolase. (237 aa)
purHBifunctional purine biosynthesis protein PurH. (392 aa)
CUN76789.1Retron-type reverse transcriptase. (132 aa)
purAAdenylosuccinate synthetase. (429 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (203 aa)
CUN81243.1Putative nicotinate-nucleotide adenylyltransferase. (190 aa)
CUN84086.1DNA polymerase III subunit delta. (347 aa)
CUN85112.1Cytidylate kinase. (198 aa)
pyrBAspartate carbamoyltransferase catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (308 aa)
pyrIAspartate carbamoyltransferase regulatory chain. (139 aa)
relAGTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (765 aa)
dinB_1DNA polymerase IV. (508 aa)
nusBN utilization substance protein B homolog; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (137 aa)
ppnKProbable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (286 aa)
CUN93033.1RNA polymerase sigma factor. (181 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (237 aa)
polC_2DNA polymerase III polC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1470 aa)
nusAN utilization substance protein A; Participates in both transcription termination and antitermination. (396 aa)
ribFRiboflavin biosynthesis protein ribF; Belongs to the ribF family. (320 aa)
CUN94560.1Cytidylate kinase. (208 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (163 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (396 aa)
spoTGuanosine-3'%2C5'-bis(diphosphate) 3'-pyrophosphohydrolase. (180 aa)
ywaC_1GTP pyrophosphokinase ywaC. (250 aa)
rfbDdTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (281 aa)
rmlCdTDP-4-dehydrorhamnose 3%2C5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (184 aa)
sigHStage 0 sporulation protein H; Belongs to the sigma-70 factor family. (200 aa)
CUO06410.1Uncharacterised protein. (194 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. (307 aa)
pyrK_2Dihydrdoorotate oxidase B%2C electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (255 aa)
pyrDDihydroorotate dehydrogenase B (NAD(+))%2C catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (300 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (227 aa)
purEN5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (167 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase. (341 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (207 aa)
purDPhosphoribosylamine--glycine ligase; Belongs to the GARS family. (423 aa)
sigF_2Stage II sporulation protein AC; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (258 aa)
queAS-adenosylmethionine:tRNA ribosyltransferase-isomerase. (342 aa)
cmkCytidylate kinase. (220 aa)
folDBifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (281 aa)
yfaYCinA-like protein; Belongs to the CinA family. (421 aa)
pflA_1-2Anaerobic ribonucleotide reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (178 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (318 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (213 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (263 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (294 aa)
cfiB_22-oxoglutarate carboxylase small subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (455 aa)
xptXanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (191 aa)
carB_2Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1075 aa)
atpD_3V-ATPase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (206 aa)
ntpBV-type sodium pump subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (461 aa)
atpA_3V-type ATP synthase alpha chain. (588 aa)
CUO21584.1V-type ATP synthase subunit E. (195 aa)
CUO21660.1V-type ATP synthase subunit K. (146 aa)
dnaC_1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (446 aa)
prsRibose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (389 aa)
ywaC_2GTP pyrophosphokinase ywaC. (216 aa)
dnaX_2DNA polymerase III subunit tau. (330 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (208 aa)
CUO31173.1DNA primase. (297 aa)
udk_1Uridine kinase. (209 aa)
rpoESigma-24. (504 aa)
dinB_2DNA polymerase IV. (504 aa)
glmUBifunctional protein GlmU. (222 aa)
sigKRNA polymerase sigma-28 factor precursor. (207 aa)
CUO40488.1ACT domain-containing protein; Belongs to the UPF0237 family. (90 aa)
coaEDephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (195 aa)
polADNA polymerase I. (879 aa)
queC7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). (221 aa)
queE7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (222 aa)
CUO41260.1Queuosine biosynthesis protein QueD. (139 aa)
udk_2Uridine kinase. (551 aa)
rpoD_1RNA polymerase sigma factor rpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (363 aa)
dnaGDNA primase. (591 aa)
rpoD_2RNA polymerase sigma factor rpoD; Belongs to the sigma-70 factor family. (256 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (80 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (205 aa)
yjbMGTP pyrophosphokinase yjbM. (267 aa)
CUO43568.1Cytidylate kinase. (198 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (375 aa)
CUO46151.1Uncharacterised protein. (188 aa)
thyA1Thymidylate synthase 1; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (282 aa)
CUO47756.1RNA polymerase sigma factor. (183 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (172 aa)
serSSerine--tRNA ligase. (428 aa)
dnaNDNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (367 aa)
CUO50160.1Cytidylate kinase. (201 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (535 aa)
Your Current Organism:
Anaerostipes hadrus
NCBI taxonomy Id: 649756
Other names: A. hadrus, ATCC 29173, Anaerostipes sp. 5/1/63FAA, Clostridiales bacterium SSC/2, DSM 3319, Eubacterium hadrum, JCM 9980, VP 82-52, VPI B2-52, butyrate-producing bacterium SS2/1, butyrate-producing bacterium SSC/2
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