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SDR93972.1 SDR93972.1 SDR82267.1 SDR82267.1 SDR83631.1 SDR83631.1 lptC lptC SDR85941.1 SDR85941.1 ftsL ftsL ftsI ftsI ftsW ftsW ftsQ ftsQ lepB lepB SDR94023.1 SDR94023.1 ftsB ftsB SDS09561.1 SDS09561.1 SDS13845.1 SDS13845.1 SDS16135.1 SDS16135.1 kdpA kdpA kdpB kdpB kdpC kdpC SDS19714.1 SDS19714.1 SDS20867.1 SDS20867.1 SDS24164.1 SDS24164.1 SDS26219.1 SDS26219.1 SDS26976.1 SDS26976.1 SDS27912.1 SDS27912.1 SDS29750.1 SDS29750.1 SDS30358.1 SDS30358.1 mgtA mgtA SDS33787.1 SDS33787.1 SDS41005.1 SDS41005.1 SDS41043.1 SDS41043.1 SDS41535.1 SDS41535.1 tolQ tolQ tolR tolR SDS51799.1 SDS51799.1 SDS56013.1 SDS56013.1 SDS60647.1 SDS60647.1 SDS67614.1 SDS67614.1 SDS67682.1 SDS67682.1 rarD rarD SDS69606.1 SDS69606.1 arnF arnF arnE arnE SDS70929.1 SDS70929.1 SDS74357.1 SDS74357.1 pstA pstA SDS79945.1 SDS79945.1 SDS82859.1 SDS82859.1 SDS83861.1 SDS83861.1 SDS87486.1 SDS87486.1 SDS89542.1 SDS89542.1 SDS95547.1 SDS95547.1 SDS95578.1 SDS95578.1 crcB crcB SDS97809.1 SDS97809.1 emrB emrB SDS99314.1 SDS99314.1 SDT04707.1 SDT04707.1 SDT04759.1 SDT04759.1 SDT05330.1 SDT05330.1 SDT10300.1 SDT10300.1 SDT13514.1 SDT13514.1 SDT14614.1 SDT14614.1 SDT16417.1 SDT16417.1 SDT19214.1 SDT19214.1 SDT20081.1 SDT20081.1 lpxL lpxL SDT22989.1 SDT22989.1 zipA zipA SDT26810.1 SDT26810.1 SDT28625.1 SDT28625.1 mltG mltG SDT29035.1 SDT29035.1 SDT30913.1 SDT30913.1 SDT31349.1 SDT31349.1 SDT32220.1 SDT32220.1 SDT32478.1 SDT32478.1 SDT32755.1 SDT32755.1 tolR-2 tolR-2 tolQ-2 tolQ-2 SDT34707.1 SDT34707.1 SDT35942.1 SDT35942.1 SDT36155.1 SDT36155.1 treR treR SDT36790.1 SDT36790.1 yajC yajC SDT37782.1 SDT37782.1 SDT37975.1 SDT37975.1 cyoD cyoD cysZ cysZ SDT39286.1 SDT39286.1 msrQ msrQ SDT40242.1 SDT40242.1 SDT41395.1 SDT41395.1 SDT43763.1 SDT43763.1 mscL mscL mrdB mrdB mrdA mrdA secY secY secE secE SDT47842.1 SDT47842.1 rarD-2 rarD-2 choW choW SDT50036.1 SDT50036.1 SDT50417.1 SDT50417.1 SDT50460.1 SDT50460.1 lgt lgt SDT53584.1 SDT53584.1 SDT54731.1 SDT54731.1 pstA-2 pstA-2 SDT56294.1 SDT56294.1 SDT57177.1 SDT57177.1 SDT57457.1 SDT57457.1 SDT58181.1 SDT58181.1 SDT59060.1 SDT59060.1 SDT60902.1 SDT60902.1 SDT61532.1 SDT61532.1 SDT62276.1 SDT62276.1 tatC tatC tatB tatB tatA tatA nhaP2 nhaP2 SDT63865.1 SDT63865.1 SDT65501.1 SDT65501.1 SDT65550.1 SDT65550.1 mviN mviN
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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SDR93972.1Hypothetical protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane. (126 aa)
SDR82267.1Predicted secreted protein. (237 aa)
SDR83631.1cation:H+ antiporter. (343 aa)
lptCLipopolysaccharide export system protein LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. (190 aa)
SDR85941.1Resistance to homoserine/threonine (RhtB) family protein. (210 aa)
ftsLCell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (97 aa)
ftsIPeptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. (581 aa)
ftsWCell division-specific peptidoglycan biosynthesis regulator FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (407 aa)
ftsQCell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (289 aa)
lepBSignal peptidase I Serine peptidase. MEROPS family S26A; Belongs to the peptidase S26 family. (284 aa)
SDR94023.1EamA-like transporter family protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane. (130 aa)
ftsBCell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (92 aa)
SDS09561.1Drug resistance transporter, EmrB/QacA subfamily; Manually curated; Belongs to the major facilitator superfamily. (505 aa)
SDS13845.1Xanthine permease. (500 aa)
SDS16135.1Fuc2NAc and GlcNAc transferase. (341 aa)
kdpAK+-transporting ATPase ATPase A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (564 aa)
kdpBK+-transporting ATPase ATPase B chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (685 aa)
kdpCK+-transporting ATPase ATPase C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (181 aa)
SDS19714.1Monovalent cation:H+ antiporter-2, CPA2 family; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (576 aa)
SDS20867.1Voltage-gated potassium channel. (274 aa)
SDS24164.1Quaternary ammonium compound-resistance protein SugE. (104 aa)
SDS26219.1Zinc transport system permease protein. (299 aa)
SDS26976.1Peptidoglycan glycosyltransferase /cell elongation-specific peptidoglycan D,D-transpeptidase. (630 aa)
SDS27912.1Bacteriophytochrome (light-regulated signal transduction histidine kinase). (736 aa)
SDS29750.1PAS domain S-box-containing protein. (651 aa)
SDS30358.1Signal transduction histidine kinase. (456 aa)
mgtAMg2+-importing ATPase. (901 aa)
SDS33787.1Two-component system, NarL family, sensor histidine kinase EvgS. (1207 aa)
SDS41005.1Outer membrane transport energization protein ExbB. (599 aa)
SDS41043.1Outer membrane transport energization protein ExbD. (141 aa)
SDS41535.1Glutathione-regulated potassium-efflux system protein KefB; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (602 aa)
tolQBiopolymer transport protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (230 aa)
tolRBiopolymer transport protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (148 aa)
SDS51799.1Two-component system, OmpR family, sensor kinase. (433 aa)
SDS56013.1Predicted arabinose efflux permease, MFS family. (403 aa)
SDS60647.1Glycine betaine/proline transport system permease protein. (317 aa)
SDS67614.1Chemosensory pili system protein ChpE. (203 aa)
SDS67682.1Arsenical pump membrane protein; Involved in arsenical resistance. Thought to form the channel of an arsenite pump; Belongs to the ArsB family. (427 aa)
rarDChloramphenicol-sensitive protein RarD. (293 aa)
SDS69606.1Signal transduction histidine kinase. (1165 aa)
arnFUndecaprenyl phosphate-alpha-L-ara4N flippase subunit ArnF; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnF family. (137 aa)
arnEUndecaprenyl phosphate-alpha-L-ara4N flippase subunit ArnE; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family. (115 aa)
SDS70929.1MFS transporter, DHA1 family, bicyclomycin/chloramphenicol resistance protein. (402 aa)
SDS74357.1MFS transporter, DHA1 family, bicyclomycin/chloramphenicol resistance protein. (402 aa)
pstAPhosphate ABC transporter membrane protein 2, PhoT family. (297 aa)
SDS79945.1Threonine/homoserine/homoserine lactone efflux protein. (202 aa)
SDS82859.1MFS transporter, FSR family, fosmidomycin resistance protein. (403 aa)
SDS83861.1Two-component system, OmpR family, sensor kinase ParS. (425 aa)
SDS87486.1H+/gluconate symporter. (463 aa)
SDS89542.1MFS transporter, NNP family, nitrate/nitrite transporter. (465 aa)
SDS95547.1Biopolymer transport protein ExbD. (142 aa)
SDS95578.1Biopolymer transport protein ExbB. (211 aa)
crcBCamphor resistance protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (124 aa)
SDS97809.1MFS transporter, DHA2 family, multidrug resistance protein. (455 aa)
emrBMFS transporter, DHA2 family, multidrug resistance protein; Belongs to the major facilitator superfamily. (509 aa)
SDS99314.1Translocation and assembly module TamB. (1223 aa)
SDT04707.1Iron complex transport system permease protein. (322 aa)
SDT04759.1Iron complex transport system permease protein. (329 aa)
SDT05330.1Iron complex transport system permease protein. (353 aa)
SDT10300.1ATP-binding cassette, subfamily B. (581 aa)
SDT13514.1DedD protein. (219 aa)
SDT14614.1Iron complex transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (334 aa)
SDT16417.1Nickel/cobalt exporter. (294 aa)
SDT19214.1MFS transporter, PPP family, 3-phenylpropionic acid transporter. (386 aa)
SDT20081.1Nucleobase:cation symporter-2, NCS2 family. (449 aa)
lpxLKDO2-lipid IV(A) lauroyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (311 aa)
SDT22989.1Na+/proline symporter. (1156 aa)
zipACell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. (287 aa)
SDT26810.1Zinc transporter. (331 aa)
SDT28625.1Transcriptional regulator, GntR family; Manually curated. (239 aa)
mltGUPF0755 protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (378 aa)
SDT29035.1Protease-4. (327 aa)
SDT30913.1Zinc transporter. (339 aa)
SDT31349.1Gluconate permease GntT. (450 aa)
SDT32220.1L-lysine exporter family protein LysE/ArgO. (199 aa)
SDT32478.1Predicted arabinose efflux permease, MFS family. (398 aa)
SDT32755.1Intracellular septation protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. (198 aa)
tolR-2Cell division and transport-associated protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (153 aa)
tolQ-2Cell division and transport-associated protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (231 aa)
SDT34707.1Signal transduction histidine kinase. (489 aa)
SDT35942.1Hypothetical protein. (155 aa)
SDT36155.1PTS system, N-acetylglucosamine-specific IIC component. (565 aa)
treRGntR family transcriptional regulator, trehalose operon transcriptional repressor. (234 aa)
SDT36790.1Putative negative regulator of RcsB-dependent stress response. (213 aa)
yajCProtein translocase subunit yajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (112 aa)
SDT37782.1Threonine/homoserine/homoserine lactone efflux protein. (211 aa)
SDT37975.1Bacteriophytochrome (light-regulated signal transduction histidine kinase). (747 aa)
cyoDCytochrome o ubiquinol oxidase operon protein cyoD. (111 aa)
cysZCysZ protein; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family. (255 aa)
SDT39286.1gluconate:H+ symporter, GntP family. (449 aa)
msrQSulfoxide reductase heme-binding subunit YedZ; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalyti [...] (206 aa)
SDT40242.1Iron complex transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (345 aa)
SDT41395.1Lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (564 aa)
SDT43763.1Carbon starvation protein. (688 aa)
mscLLarge conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. (138 aa)
mrdBCell elongation-specific peptidoglycan biosynthesis regulator RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (381 aa)
mrdAPeptidoglycan glycosyltransferase /cell elongation-specific peptidoglycan D,D-transpeptidase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (632 aa)
secYProtein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (442 aa)
secEProtein translocase subunit secE/sec61 gamma; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (122 aa)
SDT47842.1Putative membrane protein. (142 aa)
rarD-2Chloramphenicol-sensitive protein RarD. (294 aa)
choWGlycine betaine/proline transport system permease protein. (281 aa)
SDT50036.1Drug resistance transporter, EmrB/QacA subfamily; Belongs to the major facilitator superfamily. (475 aa)
SDT50417.1Membrane-bound lytic murein transglycosylase A; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (394 aa)
SDT50460.1Formate/nitrite transporter FocA, FNT family. (295 aa)
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (270 aa)
SDT53584.1Homoserine/homoserine lactone efflux protein. (210 aa)
SDT54731.1Outer membrane transport energization protein ExbD. (141 aa)
pstA-2Phosphate transport system permease protein. (556 aa)
SDT56294.1Zinc/manganese transport system permease protein. (288 aa)
SDT57177.1Sensor domain CHASE2-containing protein. (759 aa)
SDT57457.1Sulfate permease, SulP family. (522 aa)
SDT58181.1Zinc transport system permease protein. (262 aa)
SDT59060.1Major Facilitator Superfamily protein. (511 aa)
SDT60902.1Osmolarity sensor protein envZ. (437 aa)
SDT61532.1Tetratricopeptide repeat-containing protein. (1292 aa)
SDT62276.1Glycine betaine/proline transport system permease protein. (283 aa)
tatCSec-independent protein translocase protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (263 aa)
tatBSec-independent protein translocase protein TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (134 aa)
tatASec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (92 aa)
nhaP2Potassium/proton antiporter, CPA1 family; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily. (580 aa)
SDT63865.1Small multidrug resistance pump. (111 aa)
SDT65501.1Ca2+:H+ antiporter. (363 aa)
SDT65550.1Xanthine permease XanP. (464 aa)
mviNPutative peptidoglycan lipid II flippase; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (512 aa)
Your Current Organism:
Pseudomonas cedrina
NCBI taxonomy Id: 651740
Other names: CFML 96-198, CIP 105541, DSM 17516, P. cedrina, Pseudomonas cedrella, Pseudomonas cedrina corrig. Dabboussi et al. 2002 emend. Behrendt et al. 2009, Pseudomonas sp. H-R, Pseudomonas sp. HG-K2, Pseudomonas sp. LB-C, Pseudomonas sp. LB-Z10, Pseudomonas sp. LB-Z3
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