STRINGSTRING
ADU65615.1 ADU65615.1 ADU65635.1 ADU65635.1 cysN cysN nadD nadD ADU66201.1 ADU66201.1 ADU66226.1 ADU66226.1 polA polA ADU66491.1 ADU66491.1 mobA mobA ADU66609.1 ADU66609.1 ADU66659.1 ADU66659.1 dnaX dnaX rpoC rpoC rpoB rpoB ADU66698.1 ADU66698.1 ADU66724.1 ADU66724.1 ADU66822.1 ADU66822.1 selO selO pnp pnp dacA dacA ADU67127.1 ADU67127.1 ADU67129.1 ADU67129.1 ADU67181.1 ADU67181.1 ADU67182.1 ADU67182.1 ispD ispD ADU67268.1 ADU67268.1 ADU64826.1 ADU64826.1 ADU67287.1 ADU67287.1 hldE hldE dnaG dnaG kdsB kdsB ADU64944.1 ADU64944.1 ADU64965.1 ADU64965.1 ADU64996.1 ADU64996.1 ADU65003.1 ADU65003.1 ADU65034.1 ADU65034.1 rpoA rpoA ADU65118.1 ADU65118.1 rph rph ADU65309.1 ADU65309.1 ADU65340.1 ADU65340.1 coaD coaD glmU glmU glnD glnD ADU64761.1 ADU64761.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ADU65615.1Pseudaminic acid CMP-transferase; KEGG: aeh:Mlg_2324 acylneuraminate cytidylyltransferase; TIGRFAM: pseudaminic acid CMP-transferase; PFAM: acylneuraminate cytidylyltransferase. (236 aa)
ADU65635.1Hypothetical protein; KEGG: bdu:BDU_454 DNA polymerase III delta subunit. (303 aa)
cysNSulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (471 aa)
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (204 aa)
ADU66201.1TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sdl:Sdel_0392 diguanylate cyclase; SMART: GGDEF domain containing protein. (284 aa)
ADU66226.1KEGG: shw:Sputw3181_1082 DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein. (429 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (881 aa)
ADU66491.1PFAM: phosphatidate cytidylyltransferase; KEGG: aca:ACP_1613 phosphatidate cytidylyltransferase. (260 aa)
mobAMolybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (195 aa)
ADU66609.1TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: azl:AZL_009270 hypothetical protein; SMART: GGDEF domain containing protein. (342 aa)
ADU66659.1KEGG: shw:Sputw3181_1082 DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein. (426 aa)
dnaXDNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (548 aa)
rpoCDNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1346 aa)
rpoBDNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1347 aa)
ADU66698.1KEGG: dap:Dacet_0435 galactose-1-phosphate uridylyltransferase; TIGRFAM: galactose-1-phosphate uridylyltransferase. (343 aa)
ADU66724.1TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; KEGG: dak:DaAHT2_0229 diguanylate cyclase; SMART: GGDEF domain containing protein. (533 aa)
ADU66822.1PFAM: cobalbumin biosynthesis protein; KEGG: dap:Dacet_0147 cobalbumin biosynthesis protein. (171 aa)
selOProtein of unknown function UPF0061; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family. (480 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (722 aa)
dacAProtein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (259 aa)
ADU67127.1PFAM: domain of unknown function DUF1732; YicC-like domain-containing protein; KEGG: dal:Dalk_1930 YicC domain protein. (297 aa)
ADU67129.1DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (74 aa)
ADU67181.1Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (296 aa)
ADU67182.1TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: sua:Saut_1509 mannose-1-phosphate guanylyltransferase (GDP); mannose-6-phosphate isomerase, type 2; PFAM: Nucleotidyl transferase; mannose-6-phosphate isomerase type II. (463 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (223 aa)
ADU67268.1KEGG: bav:BAV0365 hypothetical protein. (261 aa)
ADU64826.1Diguanylate cyclase; SMART: GGDEF domain containing protein; TIGRFAM: diguanylate cyclase; KEGG: gur:Gura_3308 diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein. (643 aa)
ADU67287.1DNA polymerase III, alpha subunit; SMART: phosphoesterase PHP domain protein; TIGRFAM: DNA polymerase III, alpha subunit; KEGG: pca:Pcar_1222 DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type. (1163 aa)
hldErfaE bifunctional protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (493 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (601 aa)
kdsB3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (259 aa)
ADU64944.1PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: saf:SULAZ_1017 mannose-1-phosphate guanyltransferase. (834 aa)
ADU64965.1TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: tdn:Suden_1734 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Nucleotidyl transferase; mannose-6-phosphate isomerase type II; Belongs to the mannose-6-phosphate isomerase type 2 family. (470 aa)
ADU64996.1KEGG: glo:Glov_0507 UTP-glucose-1-phosphate uridylyltransferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase. (288 aa)
ADU65003.1PFAM: Polynucleotide adenylyltransferase region; KEGG: ago:AGOS_AGR118W hypothetical protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (502 aa)
ADU65034.1(Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...] (1014 aa)
rpoADNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (354 aa)
ADU65118.1KEGG: gur:Gura_2686 riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; Belongs to the ribF family. (312 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (244 aa)
ADU65309.1Hypothetical protein; KEGG: aar:Acear_0044 DNA polymerase III, delta prime subunit. (308 aa)
ADU65340.1KEGG: dbr:Deba_1961 RNA polymerase, sigma 54 subunit, RpoN; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor. (467 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (163 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (462 aa)
glnDprotein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. (897 aa)
ADU64761.1DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (368 aa)
Your Current Organism:
Desulfurispirillum indicum
NCBI taxonomy Id: 653733
Other names: D. indicum S5, Desulfurispirillum indicum S5, Desulfurispirillum indicum str. S5, Desulfurispirillum indicum strain S5, bacterium S5, dissimilatory selenate-respiring bacterium S5
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