Your Input: | |
| | dnaA | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (460 aa) |
| | ADU64761.1 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (368 aa) |
| | recF | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (343 aa) |
| | ADU64767.1 | PFAM: Integrase catalytic region; KEGG: sjp:SJA_P2-00260 transposase of IS6100. (254 aa) |
| | ADU64773.1 | KEGG: aby:ABAYE3646 integrase/recombinase (E2 protein); TIGRFAM: integron integrase; PFAM: integrase family protein; integrase domain protein SAM domain protein; Belongs to the 'phage' integrase family. (337 aa) |
| | ADU64777.1 | PFAM: transposase IS204/IS1001/IS1096/IS1165 family protein; KEGG: bxe:Bxe_C0885 transposase TnpA. (429 aa) |
| | recA | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (357 aa) |
| | ADU64837.1 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (450 aa) |
| | csrA | Carbon storage regulator; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (79 aa) |
| | ADU64873.1 | KEGG: dvm:DvMF_0050 RNP-1 like RNA-binding protein; PFAM: RNP-1 like RNA-binding protein; SMART: RNP-1 like RNA-binding protein. (83 aa) |
| | ADU64874.1 | KEGG: dvm:DvMF_0050 RNP-1 like RNA-binding protein; PFAM: RNP-1 like RNA-binding protein; SMART: RNP-1 like RNA-binding protein. (84 aa) |
| | mnmG | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (630 aa) |
| | rsmG | Methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (203 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (601 aa) |
| | sigA | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (627 aa) |
| | rsmH | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (316 aa) |
| | ADU64942.1 | KEGG: dma:DMR_21430 hypothetical protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein. (242 aa) |
| | ADU64994.1 | Hypothetical protein; Manually curated; KEGG: mgm:Mmc1_2781 hypothetical protein. (309 aa) |
| | ADU64995.1 | KEGG: mgm:Mmc1_2698 hypothetical protein. (328 aa) |
| | ADU64997.1 | PFAM: protein of unknown function DUF86; KEGG: mrb:Mrub_1240 hypothetical protein. (122 aa) |
| | ADU65003.1 | PFAM: Polynucleotide adenylyltransferase region; KEGG: ago:AGOS_AGR118W hypothetical protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (502 aa) |
| | ADU65026.1 | KEGG: dds:Ddes_2020 RNP-1 like RNA-binding protein; PFAM: RNP-1 like RNA-binding protein; SMART: RNP-1 like RNA-binding protein. (82 aa) |
| | ADU65029.1 | PFAM: (Uracil-5)-methyltransferase; KEGG: dap:Dacet_0891 (uracil-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (385 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (430 aa) |
| | ADU65062.1 | PFAM: protein of unknown function DUF195; KEGG: rpi:Rpic_0900 protein of unknown function DUF195. (508 aa) |
| | ADU65063.1 | TIGRFAM: DNA-3-methyladenine glycosylase I; KEGG: gsu:GSU0567 DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase. (187 aa) |
| | ADU65071.1 | KEGG: slt:Slit_2771 RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein. (186 aa) |
| | ADU65077.1 | PFAM: DsrE family protein; KEGG: dia:Dtpsy_2206 DsrE family protein. (118 aa) |
| | rpoA | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (354 aa) |
| | ADU65143.1 | PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: dap:Dacet_1231 tRNA/rRNA methyltransferase (SpoU). (267 aa) |
| | ADU65160.1 | PFAM: protein of unknown function DUF86; KEGG: gem:GM21_1251 protein of unknown function DUF86. (115 aa) |
| | ADU65172.1 | KEGG: glo:Glov_1954 ATP-dependent DNA helicase RecG; PFAM: DEAD/DEAH box helicase domain protein; nucleic acid binding OB-fold tRNA/helicase-type; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein. (675 aa) |
| | ADU65202.1 | Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (324 aa) |
| | ADU65214.1 | PFAM: protein of unknown function DUF523; protein of unknown function DUF1722; KEGG: nth:Nther_2140 protein of unknown function DUF1722. (308 aa) |
| | ADU65217.1 | KEGG: dak:DaAHT2_2274 competence protein ComEA helix-hairpin-helix repeat protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: helix-hairpin-helix motif. (84 aa) |
| | ADU65224.1 | AAA ATPase central domain protein; KEGG: chy:CHY_2201 recombination factor protein RarA; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase. (420 aa) |
| | ADU65225.1 | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (152 aa) |
| | ADU65226.1 | KEGG: neu:NE1223 putative transposase. (343 aa) |
| | ADU65227.1 | KEGG: bpt:Bpet3736 putative transposase. (355 aa) |
| | ADU65228.1 | KEGG: bpt:Bpet3736 putative transposase. (355 aa) |
| | trmFO | Gid protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. (438 aa) |
| | ADU65257.1 | PFAM: methyltransferase small; KEGG: sul:SYO3AOP1_0212 methyltransferase small; Belongs to the methyltransferase superfamily. (241 aa) |
| | ADU65266.1 | KEGG: gem:GM21_3513 hypothetical protein. (99 aa) |
| | ADU65269.1 | KEGG: gem:GM21_3513 hypothetical protein. (110 aa) |
| | ADU65270.1 | KEGG: gem:GM21_3513 hypothetical protein. (136 aa) |
| | ADU65271.1 | KEGG: gem:GM21_3513 hypothetical protein. (123 aa) |
| | fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (312 aa) |
| | rph | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (244 aa) |
| | ADU65298.1 | PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: gme:Gmet_0066 Fmu, rRNA SAM-dependent methyltransferase:Nop2p; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (417 aa) |
| | miaB | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (441 aa) |
| | ADU65303.1 | Sua5/YciO/YrdC/YwlC family protein; KEGG: swo:Swol_2395 hypothetical protein; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; Belongs to the SUA5 family. (204 aa) |
| | ADU65306.1 | Hydrolase, TatD family; KEGG: seu:SEQ_0330 TatD related DNase; TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease. (263 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (629 aa) |
| | ADU65309.1 | Hypothetical protein; KEGG: aar:Acear_0044 DNA polymerase III, delta prime subunit. (308 aa) |
| | ADU65311.1 | PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: swo:Swol_2044 YbaK/EbsC family protein. (307 aa) |
| | rnc | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (247 aa) |
| | ADU65340.1 | KEGG: dbr:Deba_1961 RNA polymerase, sigma 54 subunit, RpoN; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor. (467 aa) |
| | ADU65382.1 | Methyltransferase; Manually curated; TIGRFAM: methyltransferase; KEGG: mta:Moth_0936 methyltransferase small; PFAM: Conserved hypothetical protein CHP00095. (182 aa) |
| | ADU65393.1 | PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: gca:Galf_2237 UBA/ThiF-type NAD/FAD binding protein. (255 aa) |
| | ADU65397.1 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (152 aa) |
| | ADU65402.1 | KEGG: aeh:Mlg_0311 hypothetical protein. (290 aa) |
| | ADU65404.1 | Hypothetical protein; KEGG: nde:NIDE0136 putative type I restriction endonuclease, R subunit. (69 aa) |
| | ADU65410.1 | Hypothetical protein; KEGG: saf:SULAZ_0572 cytotoxic translational repressor of toxin-antitoxin system RelE. (107 aa) |
| | ADU65415.1 | KEGG: pmy:Pmen_4544 DNA polymerase III subunit epsilon; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease. (250 aa) |
| | ung | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (233 aa) |
| | ADU65437.1 | KEGG: ssm:Spirs_0440 transposase IS3/IS911 family protein; manually curated; PFAM: transposase IS3/IS911 family protein. (383 aa) |
| | ADU65451.1 | KEGG: pat:Patl_3876 methylated-DNA--protein-cysteine methyltransferase; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding. (159 aa) |
| | ADU65454.1 | KEGG: aar:Acear_1675 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (330 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (893 aa) |
| | gyrB | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (799 aa) |
| | ADU65489.1 | PFAM: protein of unknown function DUF1538; KEGG: dak:DaAHT2_1988 protein of unknown function DUF1538. (230 aa) |
| | ADU65490.1 | PFAM: protein of unknown function DUF1538; KEGG: dak:DaAHT2_1989 protein of unknown function DUF1538. (244 aa) |
| | rlmN | Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (342 aa) |
| | xseA | Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (469 aa) |
| | ADU65525.1 | PFAM: pseudouridine synthase; KEGG: gme:Gmet_0267 tRNA pseudouridine synthase C. (273 aa) |
| | ADU65529.1 | KEGG: hor:Hore_12210 single-stranded-DNA-specific exonuclease RecJ; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1. (558 aa) |
| | ADU65531.1 | PFAM: peptidase M22 glycoprotease; KEGG: cbk:CLL_A0531 glycoprotease family protein. (213 aa) |
| | ADU65533.1 | KEGG: ssm:Spirs_0440 transposase IS3/IS911 family protein; manually curated; PFAM: transposase IS3/IS911 family protein. (383 aa) |
| | ADU65534.1 | PFAM: transposase IS204/IS1001/IS1096/IS1165 family protein; KEGG: sat:SYN_01637 transposase. (404 aa) |
| | ADU65535.1 | KEGG: ssm:Spirs_0440 transposase IS3/IS911 family protein; manually curated; PFAM: transposase IS3/IS911 family protein. (383 aa) |
| | mutS2 | MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (785 aa) |
| | rnpA | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (117 aa) |
| | ADU65566.1 | PFAM: phosphoesterase DHHA1; KEGG: mag:amb3955 exopolyphosphatase-like protein. (312 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (592 aa) |
| | hisS | TIGRFAM: histidyl-tRNA synthetase; KEGG: dap:Dacet_1436 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein. (418 aa) |
| | ADU65571.1 | KEGG: dak:DaAHT2_1960 hypothetical protein. (208 aa) |
| | ADU65579.1 | KEGG: gme:Gmet_1933 heat shock protein DnaJ-like; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein. (100 aa) |
| | leuS | KEGG: dba:Dbac_0057 leucyl-tRNA synthetase; TIGRFAM: leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (822 aa) |
| | ADU65635.1 | Hypothetical protein; KEGG: bdu:BDU_454 DNA polymerase III delta subunit. (303 aa) |
| | ADU65641.1 | KEGG: dde:Dde_2388 3'-5' exonuclease; PFAM: 3'-5' exonuclease; SMART: 3'-5' exonuclease. (213 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (480 aa) |
| | ligA | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (660 aa) |
| | ADU65663.1 | KEGG: ypb:YPTS_2599 CRISPR-associated Csy4 family protein; TIGRFAM: CRISPR-associated protein, Csy4 family; PFAM: CRISPR-associated protein Csy4. (182 aa) |
| | ADU65667.1 | KEGG: ssm:Spirs_0440 transposase IS3/IS911 family protein; manually curated; PFAM: transposase IS3/IS911 family protein. (383 aa) |
| | ADU65669.1 | KEGG: ssm:Spirs_0440 transposase IS3/IS911 family protein; manually curated; PFAM: transposase IS3/IS911 family protein. (383 aa) |
| | ADU65670.1 | Hypothetical protein; Manually curated; KEGG: pol:Bpro_4964 transposase. (279 aa) |
| | cas1 | CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (325 aa) |
| | ADU65672.1 | PFAM: Exonuclease RNase T and DNA polymerase III; KEGG: glo:Glov_2482 DNA-directed DNA polymerase; SMART: Exonuclease. (169 aa) |
| | ADU65677.1 | PFAM: protein of unknown function DUF752; KEGG: sun:SUN_0204 hypothetical protein. (270 aa) |
| | ADU65682.1 | PFAM: Endonuclease/exonuclease/phosphatase; KEGG: hha:Hhal_1737 endonuclease/exonuclease/phosphatase. (554 aa) |
| | ADU65700.1 | KEGG: ssm:Spirs_0440 transposase IS3/IS911 family protein; manually curated; PFAM: transposase IS3/IS911 family protein. (383 aa) |
| | rnj | RNA-metabolising metallo-beta-lactamase; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (581 aa) |
| | ADU65712.1 | Hypothetical protein; Manually curated; KEGG: pol:Bpro_4964 transposase. (279 aa) |
| | ADU65719.1 | Addiction module toxin, RelE/StbE family; KEGG: abc:ACICU_p0010 cytotoxic translational repressor of toxin-antitoxin stability system; TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system. (99 aa) |
| | ADU65730.1 | KEGG: tcx:Tcr_1023 tRNA 2-selenouridine synthase; TIGRFAM: tRNA 2-selenouridine synthase; SMART: Rhodanese domain protein. (380 aa) |
| | ADU65733.1 | PFAM: SMC domain protein; KEGG: xom:XOO_0502 hypothetical protein. (396 aa) |
| | ADU65749.1 | Hypothetical protein; Manually curated; KEGG: pol:Bpro_4964 transposase. (279 aa) |
| | ADU65762.1 | TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; nucleic acid binding OB-fold tRNA/helicase-type; KEGG: sat:SYN_02192 HD-superfamily hydrolase; SMART: metal-dependent phosphohydrolase HD region. (375 aa) |
| | ADU65766.1 | KEGG: dol:Dole_0747 hypothetical protein. (273 aa) |
| | ADU65767.1 | TIGRFAM: CRISPR-associated protein, Csm1 family; KEGG: tye:THEYE_A0633 CRISPR-associated protein, Csm1 family. (922 aa) |
| | ADU65769.1 | KEGG: tye:THEYE_A0635 CRISPR-associated RAMP protein, Csm3 family; TIGRFAM: CRISPR-associated RAMP protein, Csm3 family; PFAM: protein of unknown function DUF324. (245 aa) |
| | ADU65773.1 | PFAM: transposase IS204/IS1001/IS1096/IS1165 family protein; KEGG: sat:SYN_01637 transposase. (404 aa) |
| | cas1-2 | CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (333 aa) |
| | cas2 | CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (91 aa) |
| | ADU65780.1 | KEGG: ava:Ava_4177 hypothetical protein. (90 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (884 aa) |
| | ADU65805.1 | KEGG: wsu:WS0596 DNA polymerase III subunit epsilon; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease. (206 aa) |
| | ADU65817.1 | PFAM: CMP/dCMP deaminase zinc-binding; KEGG: zpr:ZPR_1903 guanine deaminase. (157 aa) |
| | asnS | KEGG: pca:Pcar_0586 asparaginyl-tRNA synthetase; TIGRFAM: asparaginyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type. (448 aa) |
| | uvrC | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (604 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (404 aa) |
| | ADU65853.1 | PFAM: Radical SAM domain protein; KEGG: mem:Memar_1142 radical SAM domain-containing protein. (313 aa) |
| | rnr | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (747 aa) |
| | ruvB | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (341 aa) |
| | ruvA | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (202 aa) |
| | ruvC | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (171 aa) |
| | ADU65883.1 | PFAM: methyltransferase; KEGG: fnu:FN1606 3-deoxy-D-manno-octulosonic-acid transferase. (216 aa) |
| | ADU65887.1 | PFAM: NusB/RsmB/TIM44; KEGG: ddd:Dda3937_01957 transcription antitermination protein. (133 aa) |
| | ADU65897.1 | PFAM: formyl transferase domain protein; KEGG: ppd:Ppro_0055 methionyl-tRNA formyltransferase. (310 aa) |
| | ADU65943.1 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (278 aa) |
| | tadA | CMP/dCMP deaminase zinc-binding protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (167 aa) |
| | rimO | MiaB-like tRNA modifying enzyme YliG; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (440 aa) |
| | ADU65999.1 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (554 aa) |
| | truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (263 aa) |
| | ADU66022.1 | PFAM: protein of unknown function UPF0027; KEGG: dba:Dbac_1279 protein of unknown function UPF0027. (370 aa) |
| | ADU66039.1 | PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: bpu:BPUM_1512 site-specific tyrosine recombinase XerC; Belongs to the 'phage' integrase family. (303 aa) |
| | ADU66048.1 | Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (91 aa) |
| | ADU66051.1 | PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: lac:LBA0959 integrase-recombinase; Belongs to the 'phage' integrase family. (330 aa) |
| | lysS | KEGG: ddf:DEFDS_1155 lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; Belongs to the class-II aminoacyl-tRNA synthetase family. (498 aa) |
| | ADU66097.1 | RNA polymerase sigma factor, FliA/WhiG family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (250 aa) |
| | glyS | TIGRFAM: glycyl-tRNA synthetase, beta subunit; KEGG: gem:GM21_0656 glycyl-tRNA synthetase subunit beta; PFAM: glycyl-tRNA synthetase beta subunit. (693 aa) |
| | glyQ | TIGRFAM: glycyl-tRNA synthetase, alpha subunit; KEGG: ddf:DEFDS_0639 glycyl-tRNA synthetase subunit alpha; PFAM: glycyl-tRNA synthetase alpha subunit. (293 aa) |
| | ADU66118.1 | Hypothetical protein; KEGG: bcr:BCAH187_A2978 putative glutathionylspermidine synthase. (216 aa) |
| | ybeY | Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (152 aa) |
| | ADU66125.1 | PFAM: methyltransferase small; KEGG: vha:VIBHAR_03421 16S rRNA m2G 1207 methyltransferase. (343 aa) |
| | ADU66162.1 | KEGG: noc:Noc_0626 hypothetical protein. (184 aa) |
| | ADU66175.1 | PFAM: integrase family protein; KEGG: glo:Glov_3695 hypothetical protein. (308 aa) |
| | ADU66180.1 | DNA-cytosine methyltransferase; KEGG: pst:PSPTO_2386 C-5 cytosine-specific DNA methylase family protein; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (306 aa) |
| | ADU66204.1 | KEGG: plm:Plim_2626 single-strand binding protein; TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n. (107 aa) |
| | ADU66205.1 | Hypothetical protein; KEGG: psa:PST_2773 recombination associated protein. (288 aa) |
| | ADU66219.1 | PFAM: transposase IS204/IS1001/IS1096/IS1165 family protein; KEGG: bxe:Bxe_C0885 transposase TnpA. (430 aa) |
| | ADU66220.1 | PFAM: D12 class N6 adenine-specific DNA methyltransferase; KEGG: slp:Slip_1825 D12 class N6 adenine-specific DNA methyltransferase. (347 aa) |
| | ADU66222.1 | PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: gbm:Gbem_3678 Resolvase domain. (212 aa) |
| | ADU66224.1 | KEGG: ppu:PP_3375 deoxyribonuclease I; PFAM: Endonuclease I. (312 aa) |
| | ADU66225.1 | PFAM: Peptidase S24/S26A/S26B, conserved region; KEGG: pmr:PMI2484 DNA repair protein; Belongs to the peptidase S24 family. (150 aa) |
| | ADU66226.1 | KEGG: shw:Sputw3181_1082 DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein. (429 aa) |
| | ADU66227.1 | PFAM: integrase family protein; KEGG: ypy:YPK_0061 integrase family protein; Belongs to the 'phage' integrase family. (398 aa) |
| | ADU66244.1 | Ribonuclease, Rne/Rng family; KEGG: gur:Gura_0301 ribonuclease; TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA-binding protein AU-1/Ribonuclease E/G; RNA binding S1 domain protein. (501 aa) |
| | queH | Protein of unknown function DUF208; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (183 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (925 aa) |
| | ADU66264.1 | KEGG: dhd:Dhaf_3411 pseudouridine synthase; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; Belongs to the pseudouridine synthase RsuA family. (251 aa) |
| | nfo | Apurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (283 aa) |
| | radA | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (453 aa) |
| | nusA | Transcription termination factor NusA; Participates in both transcription termination and antitermination. (382 aa) |
| | mnmE | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (458 aa) |
| | gyrA | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (821 aa) |
| | mutS | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (838 aa) |
| | cysS | TIGRFAM: cysteinyl-tRNA synthetase; KEGG: ddf:DEFDS_0838 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; Belongs to the class-I aminoacyl-tRNA synthetase family. (465 aa) |
| | ADU66343.1 | KEGG: dps:DP2965 hypothetical protein. (335 aa) |
| | ADU66344.1 | PHP domain protein; KEGG: chy:CHY_2227 phosphotransferase domain-containing protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein. (287 aa) |
| | ADU66347.1 | TIGRFAM: MiaB-like tRNA modifying enzyme; RNA modification enzyme, MiaB family; PFAM: protein of unknown function UPF0004; Radical SAM domain protein; KEGG: sat:SYN_00797 tRNA 2-methylthioadenosine synthase -like protein; SMART: Elongator protein 3/MiaB/NifB. (426 aa) |
| | xseB | Exonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (77 aa) |
| | rbfA | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (116 aa) |
| | ADU66358.1 | PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: geo:Geob_2694 phosphoesterase RecJ domain protein. (316 aa) |
| | truB | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (293 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (881 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (216 aa) |
| | ADU66398.1 | KEGG: alv:Alvin_2062 exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase. (272 aa) |
| | ADU66433.1 | KEGG: dol:Dole_2728 hypothetical protein. (364 aa) |
| | ADU66434.1 | KEGG: dol:Dole_2727 ABC transporter. (609 aa) |
| | ADU66435.1 | PFAM: restriction modification system DNA specificity domain; KEGG: neu:NE2496 restriction modification system, type I. (527 aa) |
| | ADU66436.1 | PFAM: N-6 DNA methylase; KEGG: dol:Dole_2725 N-6 DNA methylase. (554 aa) |
| | ADU66439.1 | PFAM: type III restriction protein res subunit; protein of unknown function DUF450; KEGG: dol:Dole_2724 type III restriction protein res subunit; SMART: DEAD-like helicase. (936 aa) |
| | ADU66463.1 | RNA methyltransferase, TrmH family, group 3; KEGG: ere:EUBREC_1448 putative tRNA/rRNA methyltransferase; TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (228 aa) |
| | ADU66465.1 | RNA polymerase sigma factor, sigma-70 family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (305 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (694 aa) |
| | ADU66472.1 | KEGG: dar:Daro_1297 hypothetical protein. (196 aa) |
| | tsaD | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (329 aa) |
| | ADU66496.1 | Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (93 aa) |
| | ADU66522.1 | PFAM: transposase IS4 family protein; KEGG: mba:Mbar_A1346 transposase. (278 aa) |
| | ADU66524.1 | KEGG: xau:Xaut_2777 ECF subfamily RNA polymerase sigma-24 factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein. (171 aa) |
| | ADU66566.1 | KEGG: gur:Gura_3382 radical SAM domain-containing protein. (438 aa) |
| | ADU66567.1 | KEGG: gme:Gmet_0125 hypothetical protein. (251 aa) |
| | smc | Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1150 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (572 aa) |
| | ADU66659.1 | KEGG: shw:Sputw3181_1082 DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein. (426 aa) |
| | ADU66660.1 | PFAM: Peptidase S24/S26A/S26B, conserved region; KEGG: hha:Hhal_1278 putative prophage repressor; Belongs to the peptidase S24 family. (165 aa) |
| | recR | Zinc finger C4-type, RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (208 aa) |
| | dnaX | DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (548 aa) |
| | rpoC | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1346 aa) |
| | rpoB | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1347 aa) |
| | nusG | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. (172 aa) |
| | ADU66680.1 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (725 aa) |
| | rnhA | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (152 aa) |
| | ADU66697.1 | KEGG: pth:PTH_2227 hypothetical protein. (238 aa) |
| | ADU66715.1 | KEGG: noc:Noc_1856 hypothetical protein. (333 aa) |
| | ADU66719.1 | PFAM: Integrase catalytic region; KEGG: neu:NE0155 integrase catalytic subunit. (287 aa) |
| | ADU66720.1 | KEGG: noc:Noc_1856 hypothetical protein. (333 aa) |
| | ADU66721.1 | Transposase; Manually curated; KEGG: pol:Bpro_4964 transposase. (279 aa) |
| | ADU66731.1 | KEGG: chy:CHY_1834 CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC. (261 aa) |
| | mutL | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (595 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (312 aa) |
| | ADU66775.1 | PFAM: SapC family protein; KEGG: mgm:Mmc1_2181 SapC family protein. (234 aa) |
| | ADU66787.1 | PFAM: Methyltransferase type 11; KEGG: alv:Alvin_1115 methyltransferase type 11. (248 aa) |
| | ADU66799.1 | KEGG: tgr:Tgr7_2730 YbaK/EbsC protein; TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (158 aa) |
| | ADU66803.1 | Protein of unknown function Met10; KEGG: sat:SYN_01029 SAM-dependent methyltransferase; PFAM: protein of unknown function Met10; SMART: PUA domain containing protein. (389 aa) |
| | ADU66807.1 | PFAM: Smr protein/MutS2; KEGG: fnu:FN1563 hypothetical protein. (149 aa) |
| | ADU66821.1 | PFAM: transposase IS204/IS1001/IS1096/IS1165 family protein; KEGG: sat:SYN_01637 transposase. (404 aa) |
| | ADU66842.1 | TIGRFAM: tryptophanyl-tRNA synthetase; KEGG: cth:Cthe_0686 tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib. (327 aa) |
| | rnhB | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (201 aa) |
| | ADU66867.1 | KEGG: ssm:Spirs_0440 transposase IS3/IS911 family protein; manually curated; PFAM: transposase IS3/IS911 family protein. (383 aa) |
| | ADU66891.1 | KEGG: oih:OB1057 hypothetical protein; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease. (166 aa) |
| | ADU66906.1 | PFAM: glycosyl transferase group 1; PHP domain protein; KEGG: hya:HY04AAS1_0697 glycosyl transferase group 1. (771 aa) |
| | ADU66912.1 | PFAM: transposase IS204/IS1001/IS1096/IS1165 family protein; KEGG: sat:SYN_01637 transposase. (404 aa) |
| | ADU66918.1 | Transposase; Manually curated; KEGG: pol:Bpro_4964 transposase. (279 aa) |
| | gluQ | Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (318 aa) |
| | mnmA | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (345 aa) |
| | topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (768 aa) |
| | argS | TIGRFAM: arginyl-tRNA synthetase; KEGG: gem:GM21_1940 arginyl-tRNA synthetase. (556 aa) |
| | pnp | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (722 aa) |
| | rlmH | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (156 aa) |
| | ADU66972.1 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (313 aa) |
| | ADU66975.1 | tRNA/rRNA methyltransferase (SpoU); Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. (158 aa) |
| | ADU66990.1 | KEGG: ote:Oter_0841 hypothetical protein. (297 aa) |
| | ADU66995.1 | Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (243 aa) |
| | ADU66998.1 | KEGG: dal:Dalk_0932 SUA5/YciO/YrdC/YwlC family protein; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; Belongs to the SUA5 family. (202 aa) |
| | ADU67004.1 | KEGG: rcp:RCAP_rcc00930 hypothetical protein. (93 aa) |
| | ADU67005.1 | Transposase; Manually curated; KEGG: pol:Bpro_4964 transposase. (279 aa) |
| | ADU67009.1 | KEGG: cob:COB47_0493 anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein. (688 aa) |
| | ADU67011.1 | KEGG: pag:PLES_16511 putative sigma-70 factor, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein. (171 aa) |
| | ADU67013.1 | Transposase; Manually curated; KEGG: pol:Bpro_4964 transposase. (279 aa) |
| | ADU67016.1 | Transposase; Manually curated; KEGG: pol:Bpro_4964 transposase. (279 aa) |
| | ADU67017.1 | PFAM: D12 class N6 adenine-specific DNA methyltransferase; KEGG: dze:Dd1591_3545 D12 class N6 adenine-specific DNA methyltransferase. (312 aa) |
| | ADU67018.1 | KEGG: bth:BT_4010 hypothetical protein. (467 aa) |
| | ADU67021.1 | KEGG: cja:CJA_1583 CRISPR-associated protein, Csm2 family. (221 aa) |
| | ADU67022.1 | KEGG: cja:CJA_1584 RloA protein. (420 aa) |
| | rsmA | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (270 aa) |
| | mfd | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1048 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (416 aa) |
| | ADU67034.1 | PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: sfu:Sfum_1152 methyltransferase GidB. (248 aa) |
| | ADU67036.1 | PFAM: pseudouridine synthase; KEGG: sfu:Sfum_1153 pseudouridine synthase. (267 aa) |
| | tilS | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (442 aa) |
| | ADU67059.1 | Transposase; Manually curated; KEGG: pol:Bpro_4964 transposase. (279 aa) |
| | ADU67060.1 | KEGG: dhd:Dhaf_0643 protein of unknown function DUF262; manually curated; PFAM: protein of unknown function DUF262. (349 aa) |
| | ADU67063.1 | KEGG: noc:Noc_1856 hypothetical protein. (333 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (368 aa) |
| | ADU67085.1 | PFAM: Uncharacterised protein family UPF0079, ATPase; KEGG: aca:ACP_3160 conserved hypothetical protein TIGR00150. (156 aa) |
| | ADU67092.1 | KEGG: syp:SYNPCC7002_A1133 hypothetical protein. (248 aa) |
| | ADU67094.1 | PFAM: integrase family protein; KEGG: dat:HRM2_44450 XerD4; Belongs to the 'phage' integrase family. (303 aa) |
| | ADU67097.1 | PFAM: HNH endonuclease; KEGG: avn:Avin_48770 hypothetical protein. (251 aa) |
| | dnaJ | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (376 aa) |
| | ADU67111.1 | KEGG: gbm:Gbem_0258 iron-sulfur cluster-binding protein. (273 aa) |
| | ADU67125.1 | KEGG: hha:Hhal_2065 hypothetical protein. (426 aa) |
| | ADU67127.1 | PFAM: domain of unknown function DUF1732; YicC-like domain-containing protein; KEGG: dal:Dalk_1930 YicC domain protein. (297 aa) |
| | ADU67129.1 | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (74 aa) |
| | ADU67131.1 | KEGG: lch:Lcho_0372 phage SPO1 DNA polymerase-related protein; TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily. (279 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (657 aa) |
| | pheS | KEGG: pca:Pcar_1422 phenylalanyl-tRNA synthetase subunit alpha; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (377 aa) |
| | pheT | KEGG: mxa:MXAN_3595 phenylalanyl-tRNA synthetase subunit beta; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (793 aa) |
| | rny | YmdA/YtgF protein; Endoribonuclease that initiates mRNA decay. (518 aa) |
| | ADU67193.1 | KEGG: gem:GM21_3513 hypothetical protein. (114 aa) |
| | ADU67198.1 | Transposase; Manually curated; KEGG: mma:MM_3343 transposase. (377 aa) |
| | ADU67203.1 | KEGG: mgm:Mmc1_2863 hypothetical protein. (327 aa) |
| | ADU67225.1 | Transposase; Manually curated; KEGG: pol:Bpro_4964 transposase. (279 aa) |
| | ADU67234.1 | HhH-GPD family protein; KEGG: drt:Dret_0892 A/G-specific adenine glycosylase; PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein. (340 aa) |
| | ADU67235.1 | PFAM: UvrD/REP helicase; KEGG: noc:Noc_0988 UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. (1123 aa) |
| | ADU67236.1 | TIGRFAM: putative DNA repair protein; KEGG: nwa:Nwat_2049 putative DNA repair protein. (915 aa) |
| | ADU67237.1 | Transposase; Manually curated; KEGG: pol:Bpro_4964 transposase. (279 aa) |
| | ADU67264.1 | KEGG: gsu:GSU2749 NOL1/NOP2/sun family protein; TIGRFAM: RNA methylase, NOL1/NOP2/sun family; PFAM: Fmu (Sun) domain protein. (316 aa) |
| | uvrB | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (660 aa) |
| | ADU67268.1 | KEGG: bav:BAV0365 hypothetical protein. (261 aa) |
| | uvrA | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (941 aa) |
| | rimM | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (166 aa) |
| | trmD | tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (436 aa) |
| | ADU67287.1 | DNA polymerase III, alpha subunit; SMART: phosphoesterase PHP domain protein; TIGRFAM: DNA polymerase III, alpha subunit; KEGG: pca:Pcar_1222 DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type. (1163 aa) |
| | ADU67326.1 | KEGG: ttr:Tter_1170 DNA-3-methyladenine glycosylase; TIGRFAM: DNA-3-methyladenine glycosylase; PFAM: methylpurine-DNA glycosylase (MPG); Belongs to the DNA glycosylase MPG family. (195 aa) |
| | ADU67328.1 | PFAM: Uncharacterised protein family UPF0102; KEGG: hha:Hhal_2103 hypothetical protein; Belongs to the UPF0102 family. (102 aa) |
