STRINGSTRING
atpD atpD dnaA dnaA ADU64781.1 ADU64781.1 recA recA ADU64837.1 ADU64837.1 ADU64853.1 ADU64853.1 ADU64924.1 ADU64924.1 ADU64951.1 ADU64951.1 ADU64976.1 ADU64976.1 ADU64980.1 ADU64980.1 ADU64999.1 ADU64999.1 ADU65058.1 ADU65058.1 ADU65067.1 ADU65067.1 ADU65142.1 ADU65142.1 ADU65155.1 ADU65155.1 ADU65198.1 ADU65198.1 ADU65200.1 ADU65200.1 ADU65218.1 ADU65218.1 ADU65224.1 ADU65224.1 hslU hslU clpX clpX ADU65318.1 ADU65318.1 ADU65334.1 ADU65334.1 ADU65339.1 ADU65339.1 ADU65445.1 ADU65445.1 ADU65449.1 ADU65449.1 ADU65580.1 ADU65580.1 der der ADU65644.1 ADU65644.1 ADU65679.1 ADU65679.1 cysA cysA ADU65743.1 ADU65743.1 lolD lolD ADU65836.1 ADU65836.1 ADU65856.1 ADU65856.1 ADU65864.1 ADU65864.1 ruvB ruvB ADU65895.1 ADU65895.1 ADU65908.1 ADU65908.1 ADU65909.1 ADU65909.1 ADU65963.1 ADU65963.1 ADU65967.1 ADU65967.1 clpB clpB ADU66018.1 ADU66018.1 ADU66040.1 ADU66040.1 ADU66066.1 ADU66066.1 ADU66075.1 ADU66075.1 ADU66112.1 ADU66112.1 radA radA ADU66339.1 ADU66339.1 ADU66378.1 ADU66378.1 ADU66457.1 ADU66457.1 ADU66578.1 ADU66578.1 ADU66637.1 ADU66637.1 ADU66638.1 ADU66638.1 ADU66640.1 ADU66640.1 macB macB dnaX dnaX ADU66684.1 ADU66684.1 ADU66741.1 ADU66741.1 ADU66794.1 ADU66794.1 ADU66808.1 ADU66808.1 ADU66819.1 ADU66819.1 ADU66883.1 ADU66883.1 phnC phnC ADU66904.1 ADU66904.1 ADU66909.1 ADU66909.1 ADU66930.1 ADU66930.1 ADU66937.1 ADU66937.1 rho rho ftsH ftsH lon lon ADU67162.1 ADU67162.1 ADU67231.1 ADU67231.1 ADU67232.1 ADU67232.1 ADU67252.1 ADU67252.1 pstB pstB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
atpDATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (466 aa)
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (460 aa)
ADU64781.1Sigma-54 factor interaction domain-containing protein; KEGG: sfu:Sfum_2764 two component, sigma54 specific, fis family transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase. (450 aa)
recArecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (357 aa)
ADU64837.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (450 aa)
ADU64853.1KEGG: ttu:TERTU_1521 Nif-specific regulatory protein; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase. (499 aa)
ADU64924.1SMART: AAA ATPase; KEGG: gur:Gura_4144 AAA ATPase. (406 aa)
ADU64951.1KEGG: hch:HCH_06149 type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SMART: AAA ATPase. (605 aa)
ADU64976.1TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter related; KEGG: rce:RC1_0357 proteases secretion ATP-binding protein PrtD; SMART: AAA ATPase. (583 aa)
ADU64980.1ABC transporter related protein; KEGG: ppu:PP_1779 lipopolysaccharide ABC export system, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase. (408 aa)
ADU64999.1ATPase AAA-2 domain protein; KEGG: nde:NIDE2457 chaperone protein ClpB; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. (811 aa)
ADU65058.1KEGG: dtu:Dtur_0873 general secretory pathway protein E; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SMART: AAA ATPase. (535 aa)
ADU65067.1SMART: AAA ATPase; KEGG: ddf:DEFDS_0394 hypothetical protein. (401 aa)
ADU65142.1KEGG: nhl:Nhal_3545 sigma-54 factor interaction domain-containing protein; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase. (460 aa)
ADU65155.1AAA ATPase central domain protein; KEGG: psa:PST_3455 ATPase of the AAA+ class; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase. (699 aa)
ADU65198.1KEGG: nhl:Nhal_1910 ABC transporter related protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. (607 aa)
ADU65200.1KEGG: sta:STHERM_c05440 transcriptional regulatory protein; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase. (459 aa)
ADU65218.1KEGG: gsu:GSU2651 amino acid ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase. (243 aa)
ADU65224.1AAA ATPase central domain protein; KEGG: chy:CHY_2201 recombination factor protein RarA; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase. (420 aa)
hslUHeat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (441 aa)
clpXATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (429 aa)
ADU65318.1KEGG: dhd:Dhaf_3473 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (224 aa)
ADU65334.1Sigma-54 factor interaction domain-containing protein; KEGG: ddf:DEFDS_2111 two-component system, NtrC family, transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase. (442 aa)
ADU65339.1KEGG: hna:Hneap_0752 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase. (247 aa)
ADU65445.1KEGG: dbr:Deba_0203 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase. (245 aa)
ADU65449.1KEGG: tkm:TK90_2064 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase. (241 aa)
ADU65580.1ABC transporter related protein; KEGG: gur:Gura_3231 lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. (571 aa)
derRibosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (457 aa)
ADU65644.1KEGG: dak:DaAHT2_0079 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase. (220 aa)
ADU65679.1KEGG: pca:Pcar_0356 putative two component response regulator; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase. (461 aa)
cysASulfate ABC transporter, ATPase subunit; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (363 aa)
ADU65743.1ABC transporter related protein; KEGG: bba:Bd2129 putative ATP-binding component of a transport system; PFAM: ABC transporter related; SMART: AAA ATPase. (310 aa)
lolDABC transporter related protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (226 aa)
ADU65836.1TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; KEGG: drt:Dret_1366 ATP-dependent Clp protease, ATP-binding subunit ClpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. (747 aa)
ADU65856.1KEGG: psp:PSPPH_2038 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase. (232 aa)
ADU65864.1ABC transporter related protein; KEGG: pap:PSPA7_3489 glutathione import ATP-binding protein GsiA; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; Belongs to the ABC transporter superfamily. (542 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (341 aa)
ADU65895.1KEGG: sus:Acid_1810 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (258 aa)
ADU65908.1Sigma-54 factor interaction domain-containing protein; KEGG: bpf:BpOF4_02410 two-component response regulator in acetoacetate metabolism; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase. (458 aa)
ADU65909.1KEGG: ppd:Ppro_0384 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (638 aa)
ADU65963.1KEGG: dak:DaAHT2_2675 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase. (250 aa)
ADU65967.1Sigma-54 factor interaction domain-containing protein; KEGG: gur:Gura_2171 two component, sigma-54 specific, fis family transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase. (473 aa)
clpBATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (862 aa)
ADU66018.1TIGRFAM: general secretory pathway protein E; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; KEGG: gpb:HDN1F_34690 general secretion pathway protein E; SMART: AAA ATPase. (493 aa)
ADU66040.1ABC transporter related protein; KEGG: ccb:Clocel_1271 cell division ATP-binding protein FtsE; PFAM: ABC transporter related; SMART: AAA ATPase. (221 aa)
ADU66066.1Sigma-54 factor interaction domain-containing protein; KEGG: ddf:DEFDS_0834 two-component, sigma54 specific, transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase. (487 aa)
ADU66075.1KEGG: gur:Gura_3241 putative ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase. (559 aa)
ADU66112.1KEGG: gsu:GSU1003 nitrogen regulation protein NR(I); PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase. (481 aa)
radADNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (453 aa)
ADU66339.1KEGG: afw:Anae109_3576 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (265 aa)
ADU66378.1KEGG: hmo:HM1_2421 abc transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase. (303 aa)
ADU66457.1TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; KEGG: tra:Trad_2800 Mg chelatase, subunit ChlI; SMART: AAA ATPase. (497 aa)
ADU66578.1KEGG: wsu:WS1803 molybdenum ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase. (292 aa)
ADU66637.1KEGG: wsu:WS1265 ABC transporter ATP-binding/permease protein; PFAM: ABC transporter related; SMART: AAA ATPase. (603 aa)
ADU66638.1KEGG: dap:Dacet_1604 ABC transporter related protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. (597 aa)
ADU66640.1KEGG: pzu:PHZ_c1068 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase. (295 aa)
macBABC transporter related protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (645 aa)
dnaXDNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (548 aa)
ADU66684.1Sigma-54 factor interaction domain-containing protein; KEGG: geo:Geob_1823 two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase. (454 aa)
ADU66741.1KEGG: hha:Hhal_0379 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (474 aa)
ADU66794.1TIGRFAM: Nif-specific regulatory protein; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; KEGG: dap:Dacet_1039 transcriptional regulator, NifA subfamily, fis family; SMART: GAF domain protein; AAA ATPase. (563 aa)
ADU66808.1KEGG: cja:CJA_3618 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; Belongs to the ABC transporter superfamily. (393 aa)
ADU66819.1KEGG: gka:GK0240 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase. (620 aa)
ADU66883.1KEGG: rca:Rcas_1237 spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase; Belongs to the ABC transporter superfamily. (365 aa)
phnCPhosphonate ABC transporter, ATPase subunit; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family. (276 aa)
ADU66904.1Sigma-54 factor interaction domain-containing protein; KEGG: tal:Thal_0500 two component, sigma54 specific, transcriptional regulator, fis family; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase. (447 aa)
ADU66909.1KEGG: dde:Dde_1624 ATPase; PFAM: ABC transporter related; SMART: AAA ATPase. (255 aa)
ADU66930.1TIGRFAM: ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; KEGG: aoe:Clos_1482 flagellar protein export ATPase FliI; SMART: AAA ATPase. (439 aa)
ADU66937.1TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: sun:SUN_0485 twitching motility protein PilT; SMART: AAA ATPase. (354 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (416 aa)
ftsHATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (651 aa)
lonATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (827 aa)
ADU67162.1KEGG: plt:Plut_0344 two component fis family transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase. (445 aa)
ADU67231.1TIGRFAM: ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC; PFAM: ABC transporter related; ABC transporter transmembrane region; KEGG: afr:AFE_1390 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC; SMART: AAA ATPase. (579 aa)
ADU67232.1TIGRFAM: ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD; PFAM: ABC transporter related; ABC transporter transmembrane region; KEGG: aha:AHA_3029 cysteine/glutathione ABC transporter membrane/ATP-binding component; SMART: AAA ATPase. (588 aa)
ADU67252.1KEGG: glo:Glov_1037 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (336 aa)
pstBPhosphate ABC transporter, ATPase subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (281 aa)
Your Current Organism:
Desulfurispirillum indicum
NCBI taxonomy Id: 653733
Other names: D. indicum S5, Desulfurispirillum indicum S5, Desulfurispirillum indicum str. S5, Desulfurispirillum indicum strain S5, bacterium S5, dissimilatory selenate-respiring bacterium S5
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