STRINGSTRING
ACK68706.1 ACK68706.1 ACK68670.1 ACK68670.1 ACK68636.1 ACK68636.1 ddl ddl ACK68548.1 ACK68548.1 ACK68539.1 ACK68539.1 comB comB ACK68494.1 ACK68494.1 ACK68491.1 ACK68491.1 ACK68490.1 ACK68490.1 purU purU ACK68478.1 ACK68478.1 purM purM ACK69709.1 ACK69709.1 ACK69703.1 ACK69703.1 ACK69664.1 ACK69664.1 gpsA gpsA pyrE pyrE purK purK ACK69548.1 ACK69548.1 ACK69532.1 ACK69532.1 ACK69483.1 ACK69483.1 rpiA rpiA anmK anmK ACK69447.1 ACK69447.1 ACK69386.1 ACK69386.1 dacA dacA ACK69221.1 ACK69221.1 dut dut ACK69185.1 ACK69185.1 ACK69182.1 ACK69182.1 tmk tmk ACK69165.1 ACK69165.1 ACK69107.1 ACK69107.1 ACK69073.1 ACK69073.1 ACK69052.1 ACK69052.1 pdhA pdhA ACK68994.1 ACK68994.1 purN purN ACK68941.1 ACK68941.1 mraY mraY ACK68920.1 ACK68920.1 ACK68918.1 ACK68918.1 ACK68909.1 ACK68909.1 ACK68799.1 ACK68799.1 ACK68798.1 ACK68798.1 pyrE-2 pyrE-2 ACK70093.1 ACK70093.1 ACK70092.1 ACK70092.1 ACK70057.1 ACK70057.1 pgk pgk ACK70002.1 ACK70002.1 ACK69999.1 ACK69999.1 ACK69998.1 ACK69998.1 cugP cugP ACK69945.1 ACK69945.1 zwf zwf tal-2 tal-2 ACK69930.1 ACK69930.1 ACK69928.1 ACK69928.1 ACK69927.1 ACK69927.1 queA queA ACK69898.1 ACK69898.1 ACK69897.1 ACK69897.1 ACK69887.1 ACK69887.1 tal tal ACK69805.1 ACK69805.1 ACK69802.1 ACK69802.1 ACK69784.1 ACK69784.1 ACK69783.1 ACK69783.1 queE queE queC queC murJ murJ ACK69740.1 ACK69740.1 ACK69724.1 ACK69724.1 ACK69710.1 ACK69710.1 ACK70177.1 ACK70177.1 ACK70213.1 ACK70213.1 ispF ispF murI murI ACK70230.1 ACK70230.1 murA murA ACK70282.1 ACK70282.1 ACK70283.1 ACK70283.1 ACK70345.1 ACK70345.1 ACK70346.1 ACK70346.1 ACK70349.1 ACK70349.1 purD purD ACK70414.1 ACK70414.1 coaD coaD murF murF pyrG pyrG ACK70470.1 ACK70470.1 gpmI gpmI murC murC murB murB purS purS purQ purQ glmS glmS glk glk gpmA gpmA ACK70775.1 ACK70775.1 pyrD pyrD ACK70786.1 ACK70786.1 ACK70808.1 ACK70808.1 mtnP mtnP ACK70998.1 ACK70998.1 fabZ fabZ lpxC lpxC purC purC apt apt atpG atpG atpA atpA atpH atpH atpF atpF atpG-2 atpG-2 atpE atpE atpB atpB ACK71071.1 ACK71071.1 ACK71073.1 ACK71073.1 ACK71084.1 ACK71084.1 pyrH pyrH pyrB pyrB accA accA rlpA rlpA ACK73684.1 ACK73684.1 ACK73681.1 ACK73681.1 ispG ispG glmU glmU ACK73618.1 ACK73618.1 ACK73611.1 ACK73611.1 ACK73606.1 ACK73606.1 ACK73592.1 ACK73592.1 nanE nanE carB carB murD murD ACK73500.1 ACK73500.1 ACK73450.1 ACK73450.1 atpD atpD atpC atpC ACK73423.1 ACK73423.1 lpxA lpxA lpxB lpxB pgl pgl murQ murQ ACK73311.1 ACK73311.1 ispH ispH ACK73272.1 ACK73272.1 ACK73243.1 ACK73243.1 ACK73226.1 ACK73226.1 ACK73186.1 ACK73186.1 ACK73180.1 ACK73180.1 ACK73172.1 ACK73172.1 ACK73166.1 ACK73166.1 ACK73137.1 ACK73137.1 purA purA ACK73098.1 ACK73098.1 prs prs accD accD ACK72960.1 ACK72960.1 ACK72957.1 ACK72957.1 ACK72939.1 ACK72939.1 ACK72938.1 ACK72938.1 ACK72937.1 ACK72937.1 dxs dxs ispE ispE ACK72809.1 ACK72809.1 ACK72787.1 ACK72787.1 purL purL purF purF ACK72677.1 ACK72677.1 murE murE uppP uppP coaX coaX ACK72468.1 ACK72468.1 ACK72438.1 ACK72438.1 ACK72435.1 ACK72435.1 pyrF pyrF queG queG ACK72402.1 ACK72402.1 eno eno tpiA tpiA ACK72376.1 ACK72376.1 ACK72194.1 ACK72194.1 ACK72191.1 ACK72191.1 ACK72170.1 ACK72170.1 ldh ldh pgi pgi ACK72124.1 ACK72124.1 adk adk ispD ispD purH purH ACK71974.1 ACK71974.1 ACK71958.1 ACK71958.1 murG murG ackA ackA lpxD lpxD ACK71865.1 ACK71865.1 ACK71835.1 ACK71835.1 ACK71833.1 ACK71833.1 gmk gmk fcl fcl gmd-2 gmd-2 ACK71750.1 ACK71750.1 ACK71696.1 ACK71696.1 ACK71675.1 ACK71675.1 ACK71664.1 ACK71664.1 gmd gmd tgt tgt ACK71611.1 ACK71611.1 acsA acsA carA carA coaE coaE ACK71525.1 ACK71525.1 ACK71493.1 ACK71493.1 queF queF rodA rodA ACK71441.1 ACK71441.1 ACK71435.1 ACK71435.1 surE surE ACK71346.1 ACK71346.1 pfkA pfkA ACK71306.1 ACK71306.1 purE purE ACK71301.1 ACK71301.1 guaA guaA ndk ndk ACK71259.1 ACK71259.1 deoC deoC ACK71209.1 ACK71209.1 ACK71180.1 ACK71180.1 ACK71172.1 ACK71172.1 ACK68768.1 ACK68768.1 dxr dxr ACK68749.1 ACK68749.1 ACK68745.1 ACK68745.1 ACK68724.1 ACK68724.1 ACK68708.1 ACK68708.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ACK68706.1KEGG: amr:AM1_0644 hypothetical protein. (466 aa)
ACK68670.1KEGG: npu:Npun_R1761 phosphoribosyltransferase. (169 aa)
ACK68636.1Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (359 aa)
ddlD-alanine/D-alanine ligase; Cell wall formation. (352 aa)
ACK68548.1PFAM: NUDIX hydrolase; KEGG: mar:MAE_53370 ADP-ribose pyrophosphatase. (184 aa)
ACK68539.1KEGG: npu:Npun_F3584 cell wall hydrolase/autolysin. (450 aa)
comBPFAM: 2-phosphosulfolactate phosphatase; KEGG: mar:MAE_16000 2-phosphosulfolactate phosphatase; Belongs to the ComB family. (241 aa)
ACK68494.1KEGG: bja:bll3066 hypothetical protein. (548 aa)
ACK68491.1PFAM: glycosyl transferase group 1; KEGG: mar:MAE_15270 mannosyltransferase. (377 aa)
ACK68490.1PFAM: glycosyl transferase group 1; KEGG: npu:Npun_F4538 glycosyl transferase, group 1. (361 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (284 aa)
ACK68478.1PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: syn:sll0670 hypothetical protein. (171 aa)
purMKEGG: mar:MAE_44360 phosphoribosyl formylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. (342 aa)
ACK69709.1Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. (343 aa)
ACK69703.1TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; KEGG: amr:AM1_1950 rare lipoprotein A; Belongs to the RlpA family. (109 aa)
ACK69664.1PFAM: purine or other phosphorylase family 1; KEGG: mar:MAE_16280 uridine phosphorylase. (256 aa)
gpsAPFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: syp:SYNPCC7002_A2853 NAD+ dependent glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (307 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (203 aa)
purKPhosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (392 aa)
ACK69548.1PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: ter:Tery_4900 NAD-dependent epimerase/dehydratase. (275 aa)
ACK69532.1PFAM: glycosyl transferase family 39; KEGG: mar:MAE_24320 glycosyl transferase family 39. (466 aa)
ACK69483.1Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (324 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (237 aa)
anmKProtein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (391 aa)
ACK69447.1PFAM: GCN5-related N-acetyltransferase; KEGG: syp:SYNPCC7002_A0832 acetyltransferase. (162 aa)
ACK69386.1PFAM: protein of unknown function DUF218; KEGG: mar:MAE_59880 hypothetical protein. (230 aa)
dacAProtein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (293 aa)
ACK69221.1PFAM: O-antigen polymerase; KEGG: mar:MAE_24030 putative O-antigen polymerase. (442 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (145 aa)
ACK69185.1KEGG: amt:Amet_0868 hypothetical protein. (286 aa)
ACK69182.1PFAM: thymidylate synthase; KEGG: mar:MAE_42510 thymidylate synthase. (512 aa)
tmkdTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (207 aa)
ACK69165.1PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_3; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: npu:Npun_R0678 glycosyl transferase, group 1. (864 aa)
ACK69107.1PFAM: GCN5-related N-acetyltransferase; KEGG: ava:Ava_2943 GCN5-related N-acetyltransferase. (148 aa)
ACK69073.1Glutathione synthase; PFAM: RimK domain protein ATP-grasp; KEGG: npu:Npun_R1819 RimK domain-containing protein ATP-grasp. (622 aa)
ACK69052.1TIGRFAM: uracil phosphoribosyltransferase; KEGG: mar:MAE_21900 uracil phosphoribosyltransferase; Belongs to the UPRTase family. (216 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (344 aa)
ACK68994.1TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: mar:MAE_48990 MazG protein homolog. (277 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (212 aa)
ACK68941.1PFAM: glycosyl transferase group 1; KEGG: mar:MAE_20810 glycosyl transferase group 1. (361 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (365 aa)
ACK68920.1PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: pmf:P9303_28721 hypothetical protein. (357 aa)
ACK68918.1PFAM: protein of unknown function DUF218; KEGG: npu:Npun_F0616 hypothetical protein. (260 aa)
ACK68909.1PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: syp:SYNPCC7002_A0110 dihydrolipoamide S-acetyltransferase. (436 aa)
ACK68799.1PFAM: glycosyl transferase family 2; KEGG: ter:Tery_3753 methyltransferase type 11. (361 aa)
ACK68798.1PFAM: glycosyl transferase family 2; KEGG: ter:Tery_3753 methyltransferase type 11. (361 aa)
pyrE-2Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (482 aa)
ACK70093.1PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; NmrA family protein; KEGG: ana:alr2751 hypothetical protein. (219 aa)
ACK70092.1PFAM: glycoside hydrolase family 24; KEGG: ava:Ava_4318 glycoside hydrolase family protein. (227 aa)
ACK70057.1PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_3; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: pmn:PMN2A_0955 TPR repeat-containing protein. (217 aa)
pgkPFAM: phosphoglycerate kinase; KEGG: mar:MAE_43670 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (401 aa)
ACK70002.1dTDP-4-dehydrorhamnose reductase; PFAM: NAD-dependent epimerase/dehydratase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; KEGG: npu:Npun_F3747 dTDP-4-dehydrorhamnose reductase. (295 aa)
ACK69999.1PFAM: Mur ligase middle domain protein; domain of unknown function DUF1727; KEGG: mar:MAE_56370 UDP-N-acetylmuramyl tripeptide synthetase like. (445 aa)
ACK69998.1PFAM: CobB/CobQ domain protein glutamine amidotransferase; KEGG: mar:MAE_56360 cobyric acid synthase like. (262 aa)
cugPNucleotidyl transferase; Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate. (388 aa)
ACK69945.1PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: ava:Ava_2504 putative 6-pyruvoyl tetrahydropterin synthase. (287 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (509 aa)
tal-2Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (383 aa)
ACK69930.1TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: mar:MAE_57590 dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (354 aa)
ACK69928.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (294 aa)
ACK69927.1dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (180 aa)
queAS-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (366 aa)
ACK69898.1Conserved hypothetical protein; KEGG: ana:all1573 unknown protein. (198 aa)
ACK69897.1KEGG: ava:Ava_4179 hypothetical protein. (223 aa)
ACK69887.1PFAM: glycosyl transferase family 39; KEGG: mar:MAE_39030 glycosyl transferase family 39. (599 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 1 subfamily. (392 aa)
ACK69805.1PFAM: TPR repeat-containing protein; protein prenyltransferase alpha subunit; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: ava:Ava_3507 protein prenyltransferase, alpha subunit. (1276 aa)
ACK69802.1PFAM: MltA domain protein; 3D domain protein; KEGG: mar:MAE_15060 membrane-bound lytic transglycosylase A. (386 aa)
ACK69784.1Cellulose synthase (UDP-forming); PFAM: glycosyl transferase family 2; KEGG: amr:AM1_4956 glycosyl transferase, group 2 family protein. (718 aa)
ACK69783.1KEGG: npu:Npun_R5619 hypothetical protein. (526 aa)
queERadical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (210 aa)
queCexsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (230 aa)
murJIntegral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (538 aa)
ACK69740.1TIGRFAM: queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: syp:SYNPCC7002_A0457 6-pyruvoyl tetrahydropterin synthase. (129 aa)
ACK69724.1KEGG: npu:Npun_R5283 hypothetical protein. (250 aa)
ACK69710.16-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (403 aa)
ACK70177.1KEGG: amr:AM1_5912 hypothetical protein. (131 aa)
ACK70213.1KEGG: mar:MAE_44520 hypothetical protein. (237 aa)
ispF2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (159 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (278 aa)
ACK70230.1N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; KEGG: mar:MAE_55580 N-acetylmuramoyl-L-alanine amidase. (623 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (441 aa)
ACK70282.1Nucleotide sugar dehydrogenase; KEGG: mar:MAE_18150 UDP-glucose dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. (464 aa)
ACK70283.1PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: mar:MAE_18140 dTDP-glucose 4,6-dehydratase. (309 aa)
ACK70345.1PFAM: glycosyl transferase family 39; KEGG: ooe:OEOE_1621 4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family. (528 aa)
ACK70346.1PFAM: glycosyl transferase family 39; KEGG: mar:MAE_41930 hypothetical protein. (450 aa)
ACK70349.1TIGRFAM: stationary-phase survival protein SurE; PFAM: Survival protein SurE; KEGG: npu:Npun_R1763 stationary-phase survival protein SurE. (227 aa)
purDKEGG: mar:MAE_23150 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. (423 aa)
ACK70414.1PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KEGG: mar:MAE_45340 NAD-dependent epimerase/dehydratase. (317 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (157 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (454 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (558 aa)
ACK70470.1KEGG: mar:MAE_48110 hypothetical protein. (238 aa)
gpmIPhosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (532 aa)
murCUDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (495 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (316 aa)
purSPhosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (91 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (227 aa)
glmSGlucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (631 aa)
glkGlucokinase; KEGG: mar:MAE_27160 glucokinase; TIGRFAM: glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family. (353 aa)
gpmAPhosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (233 aa)
ACK70775.1KEGG: mar:MAE_55440 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (476 aa)
pyrDDihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (377 aa)
ACK70786.1KEGG: npu:Npun_F5248 hypothetical protein. (447 aa)
ACK70808.1KEGG: dps:DP2016 hypothetical protein. (315 aa)
mtnPMethylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (275 aa)
ACK70998.1PFAM: glutamine amidotransferase class-I; KEGG: aeh:Mlg_1637 glutamine amidotransferase class-I. (241 aa)
fabZBeta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (163 aa)
lpxCUDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (293 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: mar:MAE_31380 phosphoribosyl aminoidazole succinocarboxamide synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. (243 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (172 aa)
atpGATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (314 aa)
atpAATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (503 aa)
atpHATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (184 aa)
atpFATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (179 aa)
atpG-2H+transporting two-sector ATPase B/B' subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (143 aa)
atpEATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (81 aa)
atpBATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (252 aa)
ACK71071.1PFAM: peptidase S1 and S6 chymotrypsin/Hap; TPR repeat-containing protein; Tetratricopeptide TPR_3; Tetratricopeptide TPR_2 repeat protein; SMART: RNA-processing protein HAT helix repeating-containing protein; Tetratricopeptide domain protein; KEGG: mar:MAE_58950 probable glycosyl transferase. (565 aa)
ACK71073.1PFAM: glycosyl transferase family 9; KEGG: syp:SYNPCC7002_A1904 heptosyltransferase family protein. (320 aa)
ACK71084.1PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; KEGG: mar:MAE_31300 NAD-dependent epimerase/dehydratase. (315 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (240 aa)
pyrBTIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: mar:MAE_40920 aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (343 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (338 aa)
rlpARare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (324 aa)
ACK73684.1Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (1123 aa)
ACK73681.1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (355 aa)
ispG1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (406 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (451 aa)
ACK73618.1PFAM: ribulose-phosphate 3-epimerase; KEGG: mar:MAE_61690 pentose-5-phosphate-3-epimerase. (235 aa)
ACK73611.1KEGG: npu:Npun_F2859 hypothetical protein. (144 aa)
ACK73606.1PFAM: GCN5-related N-acetyltransferase; KEGG: oan:Oant_2552 GCN5-related N-acetyltransferase. (136 aa)
ACK73592.1PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: ava:Ava_4629 glucosamine-6-phosphate deaminase. (259 aa)
nanEN-acylglucosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (224 aa)
carBTIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: syn:sll0370 carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1082 aa)
murDUDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (449 aa)
ACK73500.1KEGG: npu:Npun_R2303 hypothetical protein. (228 aa)
ACK73450.1KEGG: mar:MAE_31110 hypothetical protein. (80 aa)
atpDATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (482 aa)
atpCATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (138 aa)
ACK73423.1PFAM: CMP/dCMP deaminase zinc-binding; KEGG: bba:Bd0085 cytidine/deoxycytidylate deaminase family protein. (158 aa)
lpxAacyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (276 aa)
lpxBlipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (384 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (239 aa)
murQGlucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (306 aa)
ACK73311.1PFAM: O-antigen polymerase; KEGG: mar:MAE_36740 integral membrane protein. (470 aa)
ispHHydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (402 aa)
ACK73272.1PFAM: NAD-dependent epimerase/dehydratase; KEGG: ava:Ava_0293 UDP-sulfoquinovose synthase. (384 aa)
ACK73243.1TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; KEGG: noc:Noc_2047 acetyl-CoA synthetase. (657 aa)
ACK73226.1KEGG: ava:Ava_0779 hypothetical protein. (569 aa)
ACK73186.1(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (749 aa)
ACK73180.1TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein; KEGG: mar:MAE_45320 pantothenate metabolism flavoprotein. (415 aa)
ACK73172.1PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mar:MAE_42440 ErfK/YbiS/YcfS/YnhG family protein. (217 aa)
ACK73166.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (701 aa)
ACK73137.1PFAM: UDP-glucuronosyl/UDP-glucosyltransferase; glycosyl transferase family 28; Glycosyltransferase 28 domain; KEGG: amr:AM1_2011 glycosyl transferase, family 28, putative. (418 aa)
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (449 aa)
ACK73098.1PFAM: glycosyl transferase family 39; KEGG: mar:MAE_53110 glycosyl transferase family 39. (830 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (330 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (317 aa)
ACK72960.1KEGG: shn:Shewana3_2008 hypothetical protein. (439 aa)
ACK72957.1Conserved hypothetical protein; KEGG: ana:alr2295 unknown protein. (467 aa)
ACK72939.1PFAM: Glycosyltransferase 28 domain; KEGG: ana:all2286 glucosyltransferase. (154 aa)
ACK72938.1PFAM: Oligosaccharide biosynthesis protein Alg14 like; KEGG: ana:all2287 glucosyltransferase. (146 aa)
ACK72937.1KEGG: mar:MAE_38390 hypothetical protein. (139 aa)
dxsDeoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (635 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (316 aa)
ACK72809.1PFAM: Transaldolase; KEGG: ter:Tery_0519 transaldolase. (211 aa)
ACK72787.1KEGG: ava:Ava_4648 glyoxalase/bleomycin resistance protein/dioxygenase. (125 aa)
purLPhosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (764 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (496 aa)
ACK72677.1Capsular exopolysaccharide family; KEGG: mar:MAE_32940 protein-tyrosine kinase; TIGRFAM: capsular exopolysaccharide family; PFAM: lipopolysaccharide biosynthesis protein. (753 aa)
murEUDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (496 aa)
uppPUndecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (320 aa)
coaXPutative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (241 aa)
ACK72468.1PFAM: glycosyl transferase family 39; KEGG: ter:Tery_3801 glycosyl transferase family protein. (606 aa)
ACK72438.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (668 aa)
ACK72435.1PFAM: Transketolase central region; Transketolase domain protein; KEGG: mar:MAE_61820 transketolase. (637 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (232 aa)
queGIron-sulfur cluster binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (306 aa)
ACK72402.1Riboflavin biosynthesis protein RibF; KEGG: ana:alr4848 riboflavin kinase/FAD synthase; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; Belongs to the ribF family. (338 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (241 aa)
ACK72376.1PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: ava:Ava_1590 fructose-bisphosphate aldolase. (360 aa)
ACK72194.1PFAM: protein of unknown function DUF218; KEGG: mar:MAE_53640 hypothetical protein. (194 aa)
ACK72191.1PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; KEGG: mar:MAE_62660 putative phosphoribosylaminoimidazole carboxylase catalytic subunit. (263 aa)
ACK72170.1PFAM: LmbE family protein; KEGG: sco:SCO7632 hypothetical protein. (283 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (331 aa)
pgiPFAM: phosphoglucose isomerase (PGI); KEGG: npu:Npun_F3925 phosphoglucose isomerase (PGI); Belongs to the GPI family. (526 aa)
ACK72124.1TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: syn:sll0421 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (422 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (187 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (229 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: mar:MAE_62320 bifunctional phosphoribosyl aminoimidazole carboxy formyl formyltransferase/inosinemonophosphate cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. (517 aa)
ACK71974.1PFAM: NUDIX hydrolase; KEGG: ana:alr3533 hypothetical protein. (186 aa)
ACK71958.1PFAM: glycosyl transferase family 2; KEGG: tel:tll0064 probable glycosyltransferase. (374 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (360 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (405 aa)
lpxDUDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (349 aa)
ACK71865.1PFAM: glycosyl transferase family 4; KEGG: mar:MAE_38790 probable glycosyl transferase. (360 aa)
ACK71835.1TIGRFAM: pyruvate kinase; PFAM: PEP-utilising protein mobile region; Pyruvate kinase barrel; Pyruvate kinase alpha/beta; KEGG: syn:sll1275 pyruvate kinase 2; Belongs to the pyruvate kinase family. (601 aa)
ACK71833.1PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: mar:MAE_05870 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (371 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (194 aa)
fclNAD-dependent epimerase/dehydratase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (312 aa)
gmd-2GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (360 aa)
ACK71750.1PFAM: DRTGG domain protein; KEGG: mar:MAE_14440 hypothetical protein. (358 aa)
ACK71696.16-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (475 aa)
ACK71675.1PFAM: metallophosphoesterase; KEGG: ana:all0250 hypothetical protein. (277 aa)
ACK71664.1PFAM: cell wall hydrolase/autolysin; SH3 type 3 domain protein; SMART: SH3 domain protein; KEGG: mar:MAE_60940 N-acetylmuramoyl-L-alanine amidase. (556 aa)
gmdNAD-dependent epimerase/dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (319 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (375 aa)
ACK71611.1PFAM: conserved hypothetical protein; KEGG: bph:Bphy_3371 hypothetical protein. (336 aa)
acsAacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (655 aa)
carATIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: mar:MAE_28430 carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (379 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (200 aa)
ACK71525.1N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; KEGG: syn:slr1910 N-acetylmuramoyl-L-alanine amidase. (332 aa)
ACK71493.1KEGG: npu:Npun_R4206 hypothetical protein. (226 aa)
queF7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (138 aa)
rodARod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (419 aa)
ACK71441.1SMART: Tetratricopeptide domain protein; KEGG: mar:MAE_58990 hypothetical protein. (414 aa)
ACK71435.1acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa)
surEStationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (271 aa)
ACK71346.1PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_3; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: npu:Npun_R0666 TPR repeat-containing protein. (632 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (360 aa)
ACK71306.1TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; KEGG: mar:MAE_58250 N-acetylglucosamine-6-phosphate deacetylase. (388 aa)
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (181 aa)
ACK71301.1KEGG: mar:MAE_21260 penicillin-binding protein; TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain. (613 aa)
guaAGMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (542 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (143 aa)
ACK71259.1PFAM: Lytic transglycosylase catalytic; KEGG: mar:MAE_31350 lytic transglycosylase catalytic precursor. (724 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (231 aa)
ACK71209.1KEGG: syn:sll0572 hypothetical protein. (469 aa)
ACK71180.1KEGG: mar:MAE_44860 putative lipid-A-disaccharide synthase. (416 aa)
ACK71172.1Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (135 aa)
ACK68768.1PFAM: ATP-grasp domain protein; KEGG: mar:MAE_29860 succinyl-CoA synthetase beta chain. (416 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (398 aa)
ACK68749.1KEGG: npu:Npun_R6206 hypothetical protein. (517 aa)
ACK68745.1PFAM: protein of unknown function DUF608; KEGG: mar:MAE_08410 glycosidase-like protein. (801 aa)
ACK68724.1KEGG: mar:MAE_07810 hypothetical protein. (719 aa)
ACK68708.1PFAM: lipopolysaccharide biosynthesis protein; KEGG: mar:MAE_32940 protein-tyrosine kinase. (760 aa)
Your Current Organism:
Gloeothece citriformis
NCBI taxonomy Id: 65393
Other names: Cyanothece sp. PCC 7424, G. citriformis PCC 7424, Gloeothece citriformis PCC 7424, Synechococcus sp. ATCC 29155 (no longer available), Synechococcus sp. PCC 7424
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