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| | trpC | PFAM: Indole-3-glycerol phosphate synthase; KEGG: ana:all0413 indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (288 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (274 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (413 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (369 aa) |
| | ACK70691.1 | PFAM: Prephenate dehydrogenase; KEGG: npu:Npun_R1269 prephenate dehydrogenase. (371 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (227 aa) |
| | ACK70625.1 | TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: mar:MAE_19270 glutamate--ammonia ligase. (473 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (373 aa) |
| | ACK70567.1 | KEGG: swi:Swit_3995 hypothetical protein. (620 aa) |
| | ACK70552.1 | TIGRFAM: serine O-acetyltransferase; KEGG: ana:alr1404 serine acetyltransferase. (309 aa) |
| | ACK70526.1 | PFAM: protein of unknown function DUF540; KEGG: ter:Tery_0890 hypothetical protein. (269 aa) |
| | ACK70518.1 | Amidohydrolase; KEGG: syn:sll0100 N-acyl-L-amino acid amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein. (395 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (331 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (352 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (558 aa) |
| | ACK70449.1 | PFAM: Prephenate dehydrogenase; NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: mar:MAE_55280 prephenate dehydrogenase. (289 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (430 aa) |
| | ACK70239.1 | KEGG: ter:Tery_4182 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase. (363 aa) |
| | ACK70116.1 | PFAM: Glycosyl transferase, family 3-like; KEGG: ava:Ava_4534 hypothetical protein. (357 aa) |
| | gcvT | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (381 aa) |
| | glsA-2 | PFAM: cyclic nucleotide-binding; Sulfate transporter/antisigma-factor antagonist STAS; Glutaminase, core; KEGG: fre:Franean1_0296 cyclic nucleotide-binding protein; Belongs to the glutaminase family. (624 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (297 aa) |
| | pheA | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: npu:Npun_R3887 prephenate dehydratase. (287 aa) |
| | ACK68754.1 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: mar:MAE_45060 homoserine dehydrogenase. (433 aa) |
| | ACK68773.1 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: npu:Npun_R1256 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (322 aa) |
| | ACK68774.1 | TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; HAD-superfamily hydrolase subfamily IB hypothetical 1; KEGG: mar:MAE_51120 haloacid dehalogenase-like hydrolase. (214 aa) |
| | mtnB | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. (205 aa) |
| | ACK68778.1 | KEGG: mar:MAE_42090 hypothetical protein. (234 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (275 aa) |
| | ACK68818.1 | PFAM: methylenetetrahydrofolate reductase; KEGG: mar:MAE_39290 methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (300 aa) |
| | trpF | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: ana:all5288 N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (220 aa) |
| | argG | PFAM: argininosuccinate synthase; KEGG: mar:MAE_02090 argininosuccinate synthetase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (401 aa) |
| | glsA | PFAM: Glutaminase, core; KEGG: ter:Tery_3991 glutaminase; Belongs to the glutaminase family. (303 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (269 aa) |
| | ACK69056.1 | TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: syn:sll1688 threonine synthase. (437 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (301 aa) |
| | ACK69094.1 | Amidohydrolase; KEGG: npu:Npun_R2370 amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein. (387 aa) |
| | dtd3 | Hydrolase, TatD family; Catalyzes the hydrolysis of D-tyrosyl-tRNA(Tyr). (270 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (296 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (350 aa) |
| | ACK69223.1 | PFAM: aminotransferase class V; KEGG: mar:MAE_48260 L-cysteine/cystine lyase. (404 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (477 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (467 aa) |
| | ACK69318.1 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (403 aa) |
| | ACK69372.1 | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: sru:SRU_0454 carboxypeptidase G2. (391 aa) |
| | ACK69414.1 | PFAM: ribulose bisphosphate carboxylase large chain; KEGG: mar:MAE_13070 2,3-diketo-5-methylthiopentyl-1-phosphate enolase. (387 aa) |
| | ACK69445.1 | PFAM: aminoglycoside phosphotransferase; KEGG: mar:MAE_18490 hypothetical protein. (349 aa) |
| | ACK69456.1 | TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Proline dehydrogenase; Aldehyde Dehydrogenase; KEGG: mar:MAE_52300 proline oxidase; Belongs to the aldehyde dehydrogenase family. (991 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (304 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (536 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (131 aa) |
| | ACK70036.1 | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: mar:MAE_08260 glutamate dehydrogenase (NADP+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (430 aa) |
| | ACK69998.1 | PFAM: CobB/CobQ domain protein glutamine amidotransferase; KEGG: mar:MAE_56360 cobyric acid synthase like. (262 aa) |
| | ACK69943.1 | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ava:Ava_2508 cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (321 aa) |
| | cbiA | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (507 aa) |
| | ACK69922.1 | SMART: zinc finger CDGSH-type domain protein; KEGG: syn:ssl3389 stress-induced protein. (78 aa) |
| | ACK69910.1 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: mar:MAE_29110 ferredoxin-dependent glutamate synthase. (1551 aa) |
| | ACK69899.1 | KEGG: mar:MAE_48120 acetolactate synthase small subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; acetolactate synthase small subunit. (175 aa) |
| | ACK69796.1 | PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: npu:Npun_R2418 alcohol dehydrogenase. (388 aa) |
| | ACK69653.1 | KEGG: fjo:Fjoh_1143 hypothetical protein. (340 aa) |
| | ACK73641.1 | KEGG: amr:AM1_0935 serine O-acetyltransferase. (177 aa) |
| | carB | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: syn:sll0370 carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1082 aa) |
| | ACK73559.1 | PFAM: protein of unknown function DUF39; KEGG: mar:MAE_17670 hypothetical protein. (403 aa) |
| | argD | TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: mar:MAE_15720 N-acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (426 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (281 aa) |
| | ACK73341.1 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: mar:MAE_50700 acetohydroxy acid synthase. (619 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (427 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (304 aa) |
| | ACK73151.1 | PFAM: GCN5-related N-acetyltransferase; KEGG: npu:Npun_R1906 GCN5-related N-acetyltransferase. (156 aa) |
| | ACK73136.1 | TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: mar:MAE_50690 D-3-phosphoglycerate dehydrogenase. (527 aa) |
| | gcvP | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (976 aa) |
| | trpA-2 | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (266 aa) |
| | ACK73092.1 | TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mar:MAE_23060 cysteine desulfurase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (420 aa) |
| | ACK73071.1 | PFAM: alpha/beta hydrolase fold; KEGG: mpt:Mpe_A0896 hypothetical protein; Belongs to the AB hydrolase superfamily. MetX family. (338 aa) |
| | ACK73064.1 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: npu:Npun_R2059 thiamine pyrophosphate binding domain-containing protein; Belongs to the TPP enzyme family. (568 aa) |
| | mtnA | Translation initiation factor, aIF-2BI family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (350 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (364 aa) |
| | ACK73000.1 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ava:Ava_1347 cysteine synthase A. (325 aa) |
| | ACK72948.1 | PFAM: Prephenate dehydrogenase; KEGG: rha:RHA1_ro06105 bifunctional chorismate mutase/prephenate dehydrogenase. (294 aa) |
| | trpD-2 | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (347 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (156 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (496 aa) |
| | ACK72652.1 | KEGG: ava:Ava_0176 L-alanine dehydrogenase; TIGRFAM: alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein; Belongs to the AlaDH/PNT family. (362 aa) |
| | mtnD | Acireductone dioxygenase ARD; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (184 aa) |
| | dapL | Aminotransferase class I and II; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (411 aa) |
| | speA | Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. (679 aa) |
| | ACK72393.1 | PFAM: aminotransferase class I and II; KEGG: mar:MAE_44340 putative aminotransferase. (400 aa) |
| | ACK72366.1 | PFAM: GCN5-related N-acetyltransferase; KEGG: ava:Ava_0977 GCN5-related N-acetyltransferase. (161 aa) |
| | ACK72297.1 | PFAM: aminotransferase class V; KEGG: amr:AM1_6324 aminotransferase, class V superfamily protein. (445 aa) |
| | ACK72184.1 | PFAM: aminotransferase class V; KEGG: mar:MAE_45040 soluble hydrogenase 42 kDa subunit. (384 aa) |
| | trpC-2 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mar:MAE_45030 indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (295 aa) |
| | trpB-2 | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (415 aa) |
| | ACK72150.1 | Aspartoacylase; KEGG: ava:Ava_1785 aspartoacylase. (123 aa) |
| | ACK72082.1 | KEGG: npu:Npun_R5750 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein. (252 aa) |
| | ACK72039.1 | TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mar:MAE_14900 NADH-dependent glutamate synthase small subunit. (494 aa) |
| | ACK72037.1 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: amr:AM1_6366 ferredoxin dependent glutamate synthase 1, putative. (1558 aa) |
| | ACK72030.1 | PFAM: Rhodanese domain protein; KEGG: mar:MAE_59020 thiosulfate sulfurtransferase. (276 aa) |
| | cobQ | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (495 aa) |
| | ACK72015.1 | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (206 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (211 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (413 aa) |
| | ACK71947.1 | Amidohydrolase; KEGG: npu:Npun_R2370 amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein. (405 aa) |
| | ACK71808.1 | TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: mar:MAE_00040 uncharacterized AIPM/Hcit synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (545 aa) |
| | proA-2 | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (417 aa) |
| | ACK71643.1 | KEGG: mar:MAE_49560 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein. (601 aa) |
| | ACK71630.1 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1183 aa) |
| | carA | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: mar:MAE_28430 carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (379 aa) |
| | ACK71345.1 | PFAM: aminotransferase class V; KEGG: mar:MAE_52910 cysteine desulfurase like. (384 aa) |
| | argH | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: mar:MAE_19870 L-argininosuccinate lyase. (462 aa) |
| | guaA | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (542 aa) |
| | ilvD | KEGG: syn:slr0452 dihydroxyacid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (561 aa) |
| | arcB | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (309 aa) |
| | dtd | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (157 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (434 aa) |
| | ACK70998.1 | PFAM: glutamine amidotransferase class-I; KEGG: aeh:Mlg_1637 glutamine amidotransferase class-I. (241 aa) |
| | mtnP | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (275 aa) |
| | ACK70993.1 | KEGG: scl:sce0892 hypothetical protein. (606 aa) |
| | ACK70919.1 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (377 aa) |
| | glmS | Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (631 aa) |
| | ACK70699.1 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: npu:Npun_R1276 thiamine pyrophosphate binding domain-containing protein; Belongs to the TPP enzyme family. (624 aa) |
