STRINGSTRING
ACK68635.1 ACK68635.1 ACK68636.1 ACK68636.1 ACK68715.1 ACK68715.1 ACK68909.1 ACK68909.1 pdhA pdhA ACK69483.1 ACK69483.1 ACK69708.1 ACK69708.1 ACK69710.1 ACK69710.1 fbp fbp pgk pgk ACK70267.1 ACK70267.1 ACK70402.1 ACK70402.1 ACK70566.1 ACK70566.1 gpmI gpmI ACK70643.1 ACK70643.1 glk glk gpmA gpmA ACK70775.1 ACK70775.1 pckA pckA ACK71187.1 ACK71187.1 pfkA pfkA acsA acsA ACK71835.1 ACK71835.1 ACK72057.1 ACK72057.1 ACK72140.1 ACK72140.1 pgi pgi ldh ldh ACK72164.1 ACK72164.1 ACK72340.1 ACK72340.1 ACK72346.1 ACK72346.1 ACK72376.1 ACK72376.1 tpiA tpiA eno eno ACK72503.1 ACK72503.1 ACK73530.1 ACK73530.1 ACK73564.1 ACK73564.1 ACK73699.1 ACK73699.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ACK68635.1PFAM: Aldehyde Dehydrogenase; KEGG: ava:Ava_3615 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (459 aa)
ACK68636.1Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (359 aa)
ACK68715.1TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: mar:MAE_50450 dihydrolipoamide dehydrogenase. (478 aa)
ACK68909.1PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: syp:SYNPCC7002_A0110 dihydrolipoamide S-acetyltransferase. (436 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (344 aa)
ACK69483.1Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (324 aa)
ACK69708.1Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. (1222 aa)
ACK69710.16-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (403 aa)
fbpPFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: syn:slr0952 fructose-1,6-bisphosphatase. (349 aa)
pgkPFAM: phosphoglycerate kinase; KEGG: mar:MAE_43670 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (401 aa)
ACK70267.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (832 aa)
ACK70402.1PEP-utilising protein mobile region; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; KEGG: npu:Npun_R6166 PEP-utilizing enzyme. (770 aa)
ACK70566.1PFAM: Aldose 1-epimerase; KEGG: neu:NE1003 aldose 1-epimerase; Belongs to the glucose-6-phosphate 1-epimerase family. (300 aa)
gpmIPhosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (532 aa)
ACK70643.1KEGG: mar:MAE_25030 NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa)
glkGlucokinase; KEGG: mar:MAE_27160 glucokinase; TIGRFAM: glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family. (353 aa)
gpmAPhosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (233 aa)
ACK70775.1KEGG: mar:MAE_55440 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (476 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (572 aa)
ACK71187.1PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; protein of unknown function DUF205; PEP-utilising protein mobile region; KEGG: mar:MAE_17610 hypothetical protein. (975 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (360 aa)
acsAacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (655 aa)
ACK71835.1TIGRFAM: pyruvate kinase; PFAM: PEP-utilising protein mobile region; Pyruvate kinase barrel; Pyruvate kinase alpha/beta; KEGG: syn:sll1275 pyruvate kinase 2; Belongs to the pyruvate kinase family. (601 aa)
ACK72057.1PFAM: iron-containing alcohol dehydrogenase; KEGG: mar:MAE_49340 aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (887 aa)
ACK72140.1PFAM: Aldehyde Dehydrogenase; KEGG: ter:Tery_2599 aldehyde dehydrogenase (acceptor). (490 aa)
pgiPFAM: phosphoglucose isomerase (PGI); KEGG: npu:Npun_F3925 phosphoglucose isomerase (PGI); Belongs to the GPI family. (526 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (331 aa)
ACK72164.1Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: mar:MAE_34890 glyceraldehyde 3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (345 aa)
ACK72340.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (793 aa)
ACK72346.1TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ana:all2810 glutathione dependent formaldehyde dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (372 aa)
ACK72376.1PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: ava:Ava_1590 fructose-bisphosphate aldolase. (360 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (241 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa)
ACK72503.1TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: syn:sll0726 phosphoglucomutase. (553 aa)
ACK73530.1TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: mar:MAE_30020 fructose-1,6-/sedoheptulose-1,7-bisphosphatase; Belongs to the FBPase class 2 family. (345 aa)
ACK73564.1PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: mar:MAE_49470 uncharacterized zinc-type alcohol dehydrogenase-like protein. (335 aa)
ACK73699.1PFAM: ROK family protein; KEGG: mar:MAE_18450 glucokinase. (298 aa)
Your Current Organism:
Gloeothece citriformis
NCBI taxonomy Id: 65393
Other names: Cyanothece sp. PCC 7424, G. citriformis PCC 7424, Gloeothece citriformis PCC 7424, Synechococcus sp. ATCC 29155 (no longer available), Synechococcus sp. PCC 7424
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