STRINGSTRING
asd asd AMQ42028.1 AMQ42028.1 gapA gapA gap gap AMQ41674.1 AMQ41674.1 gpsA gpsA AMQ41219.1 AMQ41219.1 AMQ41217.1 AMQ41217.1 AMQ42171.1 AMQ42171.1 AMQ42333.1 AMQ42333.1 sucD sucD AMQ42121.1 AMQ42121.1 AMQ42598.1 AMQ42598.1 fabG fabG AMQ42846.1 AMQ42846.1 ald ald folD folD cysG-2 cysG-2 asd-2 asd-2 pdxB pdxB AMQ43156.1 AMQ43156.1 AMQ43495.1 AMQ43495.1 AMQ43498.1 AMQ43498.1 AMQ43729.1 AMQ43729.1 AMQ43975.1 AMQ43975.1 maeA maeA AMQ44028.1 AMQ44028.1 AMQ44056.1 AMQ44056.1 AMQ44148.1 AMQ44148.1 AMQ44171.1 AMQ44171.1 AMQ44301.1 AMQ44301.1 AMQ44321.1 AMQ44321.1 AMQ44322.1 AMQ44322.1 AMQ44389.1 AMQ44389.1 AMQ44455.1 AMQ44455.1 AMQ44464.1 AMQ44464.1 AMQ44475.1 AMQ44475.1 mdh mdh proC proC AMQ44613.1 AMQ44613.1 AMQ44755.1 AMQ44755.1 AMQ44757.1 AMQ44757.1 AMQ44798.1 AMQ44798.1 AMQ44819.1 AMQ44819.1 pntA pntA aroE aroE trkA trkA AMQ41192.1 AMQ41192.1 AMQ41179.1 AMQ41179.1 cysG cysG hldD hldD tdh tdh AMQ41109.1 AMQ41109.1 ilvC ilvC AMQ41070.1 AMQ41070.1 fabV fabV AMQ40909.1 AMQ40909.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (370 aa)
AMQ42028.1Glycerate dehydrogenase; Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (318 aa)
gapAGlyceraldehyde-3-phosphate dehydrogenase; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate. (336 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (331 aa)
AMQ41674.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (226 aa)
gpsAGlycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (334 aa)
AMQ41219.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
AMQ41217.1Nucleoside-diphosphate sugar epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
AMQ42171.1Malate dehydrogenase; Malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; Derived by automated computational analysis using gene prediction method: Protein Homology. (571 aa)
AMQ42333.13-beta hydroxysteroid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
AMQ42121.13-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
AMQ42598.1NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1612 aa)
fabG3-ketoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa)
AMQ42846.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
aldAlanine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AlaDH/PNT family. (371 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa)
cysG-2Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (463 aa)
asd-2Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (338 aa)
pdxBErythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. (373 aa)
AMQ43156.1D-3-phosphoglycerate dehydrogenase; Catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (410 aa)
AMQ43495.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
AMQ43498.1Potassium transporter Kef; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (524 aa)
AMQ43729.12,3-dihydroxybenzoate-2,3-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
AMQ43975.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
maeAMalate dehydrogenase; Malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; Derived by automated computational analysis using gene prediction method: Protein Homology. (564 aa)
AMQ44028.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (516 aa)
AMQ44056.1Potassium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (650 aa)
AMQ44148.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (317 aa)
AMQ44171.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
AMQ44301.1NADPH:quinone reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. (338 aa)
AMQ44321.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
AMQ44322.1Protein CapI; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
AMQ44389.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
AMQ44455.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
AMQ44464.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
AMQ44475.1Quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (311 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (274 aa)
AMQ44613.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. (818 aa)
AMQ44755.1Potassium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (618 aa)
AMQ44757.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (240 aa)
AMQ44798.1Potassium transporter KtrA; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
AMQ44819.1Pteridine reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
pntANAD(P) transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. (508 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (273 aa)
trkAInvolved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
AMQ41192.1Lactate dehydrogenase; Fermentative; catalyzes the formationof pyruvate from lactate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)
AMQ41179.1UDP-galactose-4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (337 aa)
cysGSiroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (466 aa)
hldDADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (319 aa)
tdhL-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (342 aa)
AMQ41109.1Quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (493 aa)
AMQ41070.1Protein acetyltransferase; Catalyzes the acetylation of lysine; Derived by automated computational analysis using gene prediction method: Protein Homology. (860 aa)
fabVtrans-2-enoyl-CoA reductase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (395 aa)
AMQ40909.1Catalyzes the formation of S-formylglutathione from S-(hydroxymethyl)glutathione; also catalyzes the formation of aldehyde or ketone from alcohols; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (375 aa)
Your Current Organism:
Aeromonas veronii
NCBI taxonomy Id: 654
Other names: A. veronii, ATCC 35624, ATCC 49904 [[Aeromonas ichthiosmia]], Aeromonas culicicola, Aeromonas culicicola Pidiyar et al. 2002, Aeromonas hybridization group 10 (HG10), Aeromonas ichthiosmia, Aeromonas sp. G18, Aeromonas sp. R1, Aeromonas sp. R9, Aeromonas sp. TH074, Aeromonas sp. TH076, CCUG 27821, CECT 4257, CECT 4486 [[Aeromonas ichthiosmia]], CIP 103438, CIP 104613 [[Aeromonas ichthiosmia]], CIP 107763 [[Aeromonas culicicola]], DSM 6393 [[Aeromonas ichthiosmia]], DSM 7386, Enteric Group 77, JCM 7375, JCM 8354 [[Aeromonas ichthiosmia]], LMG 12645 [[Aeromonas ichthiosmia]], LMG:12645 [[Aeromonas ichthiosmia]], MTCC 3249 [[Aeromonas culicicola]], NCIMB 13205 [[Aeromonas ichthiosmia]], NICM 5147 [[Aeromonas culicicola]], strain 115/II [[Aeromonas ichthiosmia]]
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