STRINGSTRING
ARN79722.1 ARN79722.1 ARN79813.1 ARN79813.1 ARN79831.1 ARN79831.1 ARN79900.1 ARN79900.1 ARN79986.1 ARN79986.1 ARN79987.1 ARN79987.1 ARN83299.1 ARN83299.1 ARN80158.1 ARN80158.1 ARN80159.1 ARN80159.1 ARN80176.1 ARN80176.1 ARN80282.1 ARN80282.1 ARN80316.1 ARN80316.1 ARN80406.1 ARN80406.1 ARN80407.1 ARN80407.1 ARN83362.1 ARN83362.1 ARN80558.1 ARN80558.1 ARN80576.1 ARN80576.1 ARN80594.1 ARN80594.1 ARN80634.1 ARN80634.1 ARN83424.1 ARN83424.1 ARN80879.1 ARN80879.1 ARN81002.1 ARN81002.1 ARN81003.1 ARN81003.1 ARN81004.1 ARN81004.1 ARN81005.1 ARN81005.1 ARN81216.1 ARN81216.1 ARN81298.1 ARN81298.1 ARN81480.1 ARN81480.1 ARN81584.1 ARN81584.1 acsA acsA ackA ackA ARN81845.1 ARN81845.1 ARN81849.1 ARN81849.1 ARN81885.1 ARN81885.1 ARN81886.1 ARN81886.1 ARN81887.1 ARN81887.1 ARN81921.1 ARN81921.1 ARN81922.1 ARN81922.1 ARN82050.1 ARN82050.1 ARN82146.1 ARN82146.1 ARN82247.1 ARN82247.1 ARN82382.1 ARN82382.1 ARN82393.1 ARN82393.1 ARN83724.1 ARN83724.1 ARN82399.1 ARN82399.1 ARN82400.1 ARN82400.1 ARN83726.1 ARN83726.1 ARN83725.1 ARN83725.1 ARN82401.1 ARN82401.1 ARN82402.1 ARN82402.1 ARN82403.1 ARN82403.1 ARN82404.1 ARN82404.1 ARN82549.1 ARN82549.1 sucC-2 sucC-2 sucD-2 sucD-2 ARN82592.1 ARN82592.1 ARN82727.1 ARN82727.1 ARN82887.1 ARN82887.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARN79722.1CoA ester lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (347 aa)
ARN79813.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
ARN79831.1methylmalonyl-CoA decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (272 aa)
ARN79900.1methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
ARN79986.1Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (564 aa)
ARN79987.1Aldehyde dehydrogenase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
ARN83299.1crotonyl-CoA carboxylase/reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa)
ARN80158.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
ARN80159.1beta-ketoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
ARN80176.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (573 aa)
ARN80282.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
ARN80316.13-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HIBADH-related family. (296 aa)
ARN80406.1Electron transfer flavoprotein subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
ARN80407.1Electron transfer flavoprotein subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
ARN83362.13-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
ARN80558.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
ARN80576.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
ARN80594.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
ARN80634.1Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (559 aa)
ARN83424.1Acyl CoA:acetate/3-ketoacid CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (646 aa)
ARN80879.1Catalyzes the oxidation of acetaldehyde, benzaldehyde, propionaldehyde and other aldehydes; Derived by automated computational analysis using gene prediction method: Protein Homology. (505 aa)
ARN81002.1Ferredoxin family protein; Could be a 3Fe-4S cluster-containing protein. (97 aa)
ARN81003.1Nitrogen fixation protein FixC; Part of an electron transfer system. Belongs to the ETF-QO/FixC family. (435 aa)
ARN81004.1Electron transfer flavoprotein subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
ARN81005.1Nitrogen fixation protein FixA; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
ARN81216.1Aldehyde dehydrogenase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (510 aa)
ARN81298.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (617 aa)
ARN81480.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (511 aa)
ARN81584.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (718 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (644 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (396 aa)
ARN81845.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (95 aa)
ARN81849.1Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
ARN81885.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (596 aa)
ARN81886.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
ARN81887.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (728 aa)
ARN81921.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (127 aa)
ARN81922.1Catalyzes the oxidation of acetaldehyde, benzaldehyde, propionaldehyde and other aldehydes; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
ARN82050.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
ARN82146.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (557 aa)
ARN82247.1acetyl/propionyl-CoA carboxylase subuit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (669 aa)
ARN82382.1Acyl dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
ARN82393.1Methylmalonate-semialdehyde dehydrogenase (CoA acylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa)
ARN83724.1acetoacetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (651 aa)
ARN82399.1acyl-CoA dehydrogenase; Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
ARN82400.1methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (535 aa)
ARN83726.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
ARN83725.13-methylcrotonyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (679 aa)
ARN82401.1hydroxymethylglutaryl-CoA lyase; Catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
ARN82402.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
ARN82403.13-hydroxyisobutyryl-CoA hydrolase; Catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
ARN82404.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
ARN82549.1Protein meaA; Derived by automated computational analysis using gene prediction method: Protein Homology. (656 aa)
sucC-2succinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)
sucD-2succinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa)
ARN82592.1CoA ester lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (323 aa)
ARN82727.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
ARN82887.13-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
Your Current Organism:
Methylocystis bryophila
NCBI taxonomy Id: 655015
Other names: DSM 21852, M. bryophila, Methylocystis bryophila Belova et al. 2013, Methylocystis sp. H2s, Methylocystis sp. S284, VKM B-2545, strain H2s
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