(33 nodes) RAB geranylgeranylation, and HOPS complex network (Metarhizium acridum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_00619	VPS9 domain protein. (711 aa)
	MAC_00652	N-acetyltransferase domain-containing protein. (254 aa)
	MAC_00732	Rab GDP dissociation inhibitor; Belongs to the Rab GDI family. (533 aa)
	MAC_00993	Vacuolar protein sorting 33A-like protein; Belongs to the STXBP/unc-18/SEC1 family. (1739 aa)
	MAC_01070	Uncharacterized protein. (535 aa)
	MAC_01071	Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. (329 aa)
	MAC_01810	Uncharacterized protein. (335 aa)
	MAC_01855	AvaB protein. (1059 aa)
	MAC_01889	Vacuolar protein sorting-associated protein 45; Belongs to the STXBP/unc-18/SEC1 family. (558 aa)
	MAC_02022	TBC domain protein, putative. (895 aa)
	MAC_02059	Uncharacterized protein. (226 aa)
	MAC_02524	Rab5-like protein ypt51. (246 aa)
	MAC_02777	Putative PEP5 protein. (1209 aa)
	MAC_02800	Protein prenyltransferase alpha subunit repeat protein. (370 aa)
	MAC_03044	Guanine nucleotide exchange factor Vps9. (858 aa)
	MAC_03542	Small GTP-binding protein YPTI. (208 aa)
	MAC_03924	Putative Ras-related protein Rab7. (187 aa)
	MAC_04131	Vacuolar protein sorting-associated protein. (741 aa)
	MAC_04287	Vacuolar segregation protein (Pep7), putative. (667 aa)
	MAC_04893	Rab proteins geranylgeranyltransferase; Belongs to the Rab GDI family. (493 aa)
	MAC_05047	Vacuolar protein sorting protein DigA. (966 aa)
	MAC_05503	Ras family GTPase. (308 aa)
	MAC_06020	DUF2263 domain-containing protein. (318 aa)
	MAC_06161	Vacuolar fusion protein mon-1. (599 aa)
	MAC_06233	Golgi complex component. (1550 aa)
	MAC_06394	Ras-like GTP-binding protein, putative. (303 aa)
	MAC_06727	Putative GTPase activating protein. (814 aa)
	MAC_07272	Rab5-like protein ypt5. (230 aa)
	MAC_07361	MBOAT_2 domain-containing protein. (286 aa)
	MAC_08169	RAS small monomeric GTPase Rab6. (490 aa)
	MAC_08574	Putative TGF beta receptor associated protein 1. (771 aa)
	MAC_09435	Putative GTP-binding protein rab2. (258 aa)
	MAC_09484	Vacuolar assembly protein, putative. (1313 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00619	MAC_02524	E9DSM1	E9DY26	VPS9 domain protein.	Rab5-like protein ypt51.	0.702
MAC_00619	MAC_03044	E9DSM1	E9DZJ6	VPS9 domain protein.	Guanine nucleotide exchange factor Vps9.	0.796
MAC_00619	MAC_06394	E9DSM1	E9E946	VPS9 domain protein.	Ras-like GTP-binding protein, putative.	0.672
MAC_00619	MAC_07272	E9DSM1	E9EBM4	VPS9 domain protein.	Rab5-like protein ypt5.	0.702
MAC_00619	MAC_08169	E9DSM1	E9EE71	VPS9 domain protein.	RAS small monomeric GTPase Rab6.	0.469
MAC_00652	MAC_01889	E9DSQ4	E9DW91	N-acetyltransferase domain-containing protein.	Vacuolar protein sorting-associated protein 45; Belongs to the STXBP/unc-18/SEC1 family.	0.469
MAC_00652	MAC_02524	E9DSQ4	E9DY26	N-acetyltransferase domain-containing protein.	Rab5-like protein ypt51.	0.402
MAC_00652	MAC_03924	E9DSQ4	E9E226	N-acetyltransferase domain-containing protein.	Putative Ras-related protein Rab7.	0.412
MAC_00652	MAC_04287	E9DSQ4	E9E339	N-acetyltransferase domain-containing protein.	Vacuolar segregation protein (Pep7), putative.	0.939
MAC_00652	MAC_06394	E9DSQ4	E9E946	N-acetyltransferase domain-containing protein.	Ras-like GTP-binding protein, putative.	0.402
MAC_00652	MAC_07272	E9DSQ4	E9EBM4	N-acetyltransferase domain-containing protein.	Rab5-like protein ypt5.	0.402
MAC_00732	MAC_01070	E9DSY4	E9DTX2	Rab GDP dissociation inhibitor; Belongs to the Rab GDI family.	Uncharacterized protein.	0.528
MAC_00732	MAC_01071	E9DSY4	E9DTX3	Rab GDP dissociation inhibitor; Belongs to the Rab GDI family.	Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.	0.528
MAC_00732	MAC_01810	E9DSY4	E9DW12	Rab GDP dissociation inhibitor; Belongs to the Rab GDI family.	Uncharacterized protein.	0.425
MAC_00732	MAC_02524	E9DSY4	E9DY26	Rab GDP dissociation inhibitor; Belongs to the Rab GDI family.	Rab5-like protein ypt51.	0.820
MAC_00732	MAC_02800	E9DSY4	E9DYV2	Rab GDP dissociation inhibitor; Belongs to the Rab GDI family.	Protein prenyltransferase alpha subunit repeat protein.	0.493
MAC_00732	MAC_03542	E9DSY4	E9E0Z4	Rab GDP dissociation inhibitor; Belongs to the Rab GDI family.	Small GTP-binding protein YPTI.	0.998
MAC_00732	MAC_03924	E9DSY4	E9E226	Rab GDP dissociation inhibitor; Belongs to the Rab GDI family.	Putative Ras-related protein Rab7.	0.954
MAC_00732	MAC_05503	E9DSY4	E9E6K5	Rab GDP dissociation inhibitor; Belongs to the Rab GDI family.	Ras family GTPase.	0.470
MAC_00732	MAC_06161	E9DSY4	E9E8G3	Rab GDP dissociation inhibitor; Belongs to the Rab GDI family.	Vacuolar fusion protein mon-1.	0.782