(106 nodes) Mixed, incl. Multivesicular body sorting pathway, and Microbody membrane network (Metarhizium acridum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_00205	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family. (430 aa)
	MAC_00207	Endosome-associated ubiquitin isopeptidase (AmsH). (476 aa)
	MAC_00388	pH-response transcription factor pacC/RIM101. (592 aa)
	MAC_00119	AAA family ATPase; Belongs to the AAA ATPase family. (774 aa)
	MAC_00527	Uncharacterized protein. (321 aa)
	MAC_00611	DUF4203 domain-containing protein. (1177 aa)
	MAC_00612	Uncharacterized protein. (502 aa)
	MAC_00613	Erf4 domain-containing protein. (597 aa)
	MAC_00691	Uncharacterized protein. (299 aa)
	MAC_00704	Peroxisome targeting signal type 2 receptor. (341 aa)
	MAC_00888	pH signal transduction protein PalI, putative. (663 aa)
	MAC_00930	EAF domain-containing protein. (336 aa)
	MAC_01076	Peroxin-1, putative. (1217 aa)
	MAC_01127	Phytanoyl-CoA dioxygenase family protein. (310 aa)
	MAC_01168	Peroxin. (386 aa)
	MAC_01190	Penicillopepsin; Belongs to the peptidase A1 family. (514 aa)
	MAC_01242	Uncharacterized protein. (271 aa)
	MAC_01243	HD_domain domain-containing protein. (220 aa)
	MAC_01273	Vacuolar protein sorting protein (Vps36), putative. (744 aa)
	MAC_01275	F-box domain containing protein. (285 aa)
	MAC_01276	Uncharacterized protein. (366 aa)
	MAC_01371	Peroxisome biosynthesis protein (PAS10/Peroxin-12), putative. (426 aa)
	MAC_01391	Aspartyl protease; Belongs to the peptidase A1 family. (408 aa)
	MAC_01434	Uncharacterized protein. (217 aa)
	MAC_01646	ESCRT-III component. (452 aa)
	MAC_01664	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (265 aa)
	MAC_01705	Uncharacterized protein. (212 aa)
	MAC_01941	Mpv17/PMP22 family protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (273 aa)
	MAC_02033	Magnesium-dependent phosphatase-1 family protein. (225 aa)
	MAC_02182	Integral membrane protein, Mpv17/PMP22 family, putative; Belongs to the peroxisomal membrane protein PXMP2/4 family. (242 aa)
	MAC_02185	Uncharacterized protein. (393 aa)
	MAC_02211	pH-response regulator protein palA/RIM20. (934 aa)
	MAC_02403	MYND domain protein (SamB). (648 aa)
	MAC_02468	Uncharacterized protein. (522 aa)
	MAC_02543	Uncharacterized protein. (368 aa)
	MAC_02551	pH signaling pathway protein. (786 aa)
	MAC_02614	ESCRT-III component. (223 aa)
	MAC_02650	Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane. (755 aa)
	MAC_02651	Ubiquitin carboxyl-terminal hydrolase 2; Belongs to the peptidase C19 family. (1031 aa)
	MAC_02712	Tubulin-tyrosine ligase. (772 aa)
	MAC_02713	Uncharacterized protein. (425 aa)
	MAC_02734	Transcription factor Rap1, putative. (706 aa)
	MAC_03080	Peroxisomal membrane protein (PmpP24), putative. (240 aa)
	MAC_03139	Peroxin 3. (530 aa)
	MAC_03416	Peroxisomal membrane anchor protein (Pex14), putative. (346 aa)
	MAC_03432	Class E vacuolar protein-sorting machinery protein HSE1. (629 aa)
	MAC_03436	Tubulin-tyrosine ligase. (381 aa)
	MAC_03494	Vacuolar protein-sorting-associated protein. (195 aa)
	MAC_03505	C2H2 finger domain protein, putative. (356 aa)
	MAC_03523	BSD domain-containing protein. (401 aa)
	MAC_03533	SNF7 family protein. (199 aa)
	MAC_03578	Charged multivesicular body protein 3. (218 aa)
	MAC_03651	ABC transporter domain-containing protein. (709 aa)
	MAC_03753	Peflin. (290 aa)
	MAC_03755	RfeD protein. (395 aa)
	MAC_03987	ESCRT-III component. (110 aa)
	MAC_04184	Cyclin-like protein (Clg1), putative. (332 aa)
	MAC_04203	Putative peroxisomal targeting signal receptor. (650 aa)
	MAC_04276	Uncharacterized protein. (229 aa)
	MAC_04797	Protein YOP1. (384 aa)
	MAC_04914	Integral membrane protein, Mpv17/PMP22 family, putative; Belongs to the peroxisomal membrane protein PXMP2/4 family. (175 aa)
	MAC_04950	YcaC related amidohydrolase. (240 aa)
	MAC_05310	Glutathione-dependent formaldehyde-activating. (239 aa)
	MAC_05525	Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (238 aa)
	MAC_05767	Zn cluster transcription factor Rds2, putative. (485 aa)
	MAC_05822	Putative chromatin modifying protein 1b. (204 aa)
	MAC_06222	Kelch repeat protein. (766 aa)
	MAC_06471	Peroxisomal carrier protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (404 aa)
	MAC_06472	Calpain-7; Belongs to the peptidase C2 family. (626 aa)
	MAC_06486	Peroxisomal adenine nucleotide transporter 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (327 aa)
	MAC_06577	Uncharacterized protein. (362 aa)
	MAC_06773	Vacuolar protein-sorting protein BRO1. (994 aa)
	MAC_06898	Calcium-binding mitochondrial carrier protein Aralar2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (257 aa)
	MAC_06908	Sulfate transporter, putative. (448 aa)
	MAC_07071	pH response protein PalF. (836 aa)
	MAC_07205	Putative peroxisomal membrane protein PMP47B; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa)
	MAC_07220	Acyl CoA binding family protein. (299 aa)
	MAC_07284	Uncharacterized protein. (331 aa)
	MAC_07289	Pex13 protein. (404 aa)
	MAC_07385	Peroxisomal biogenesis factor 6. (1373 aa)
	MAC_07631	Peroxisomal ABC transporter. (865 aa)
	MAC_07899	ATPase family AAA domain-containing protein 1; Belongs to the AAA ATPase family. (368 aa)
	MAC_07951	C6 finger domain protein, putative. (520 aa)
	MAC_07952	Mitochondrial carrier protein RIM2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (397 aa)
	MAC_08049	Uncharacterized protein. (2173 aa)
	MAC_08056	Mitochondrial AAA ATPase, putative. (1013 aa)
	MAC_08094	Peroxisomal biogenesis factor (PEX11), putative. (241 aa)
	MAC_08131	RING-1 like protein. (283 aa)
	MAC_08185	Vacuolar sorting protein SNF7 family protein, putative. (455 aa)
	MAC_08257	Putative nitrate assimilation regulatory protein nirA. (1097 aa)
	MAC_08368	Integral membrane protein, Mpv17/PMP22 family, putative; Belongs to the peroxisomal membrane protein PXMP2/4 family. (161 aa)
	MAC_08470	Charged multivesicular body protein 3. (156 aa)
	MAC_08663	Leucine Rich Repeat domain protein. (698 aa)
	MAC_08823	Nuclease domain containing protein. (265 aa)
	MAC_09050	Regulatory protein ral2. (1065 aa)
	MAC_09069	Meiotically up-regulated protein. (1211 aa)
	MAC_09325	C3H1-type domain-containing protein. (624 aa)
	MAC_09330	pH-response regulator protein palC. (481 aa)
	MAC_09411	TGc domain-containing protein. (713 aa)
	MAC_09527	ATPase; Belongs to the AAA ATPase family. (831 aa)
	MAC_09548	Phytanoyl-CoA dioxygenase. (329 aa)
	MAC_09550	NAD(P)-bd_dom domain-containing protein. (305 aa)
	MAC_09553	Phytanoyl-CoA dioxygenase. (307 aa)
	MAC_09616	Senescence domain-containing protein. (513 aa)
	MAC_09782	Amino acid transporter arg-13; Belongs to the mitochondrial carrier (TC 2.A.29) family. (333 aa)
	MAC_09828	Short chain dehydrogenase. (307 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00119	MAC_00205	E9DS46	E9DR36	AAA family ATPase; Belongs to the AAA ATPase family.	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	0.690
MAC_00119	MAC_00691	E9DS46	E9DSU3	AAA family ATPase; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.934
MAC_00119	MAC_01168	E9DS46	E9DU70	AAA family ATPase; Belongs to the AAA ATPase family.	Peroxin.	0.444
MAC_00119	MAC_01371	E9DS46	E9DUS3	AAA family ATPase; Belongs to the AAA ATPase family.	Peroxisome biosynthesis protein (PAS10/Peroxin-12), putative.	0.449
MAC_00119	MAC_01646	E9DS46	E9DVJ8	AAA family ATPase; Belongs to the AAA ATPase family.	ESCRT-III component.	0.773
MAC_00119	MAC_02614	E9DS46	E9DYB6	AAA family ATPase; Belongs to the AAA ATPase family.	ESCRT-III component.	0.594
MAC_00119	MAC_03416	E9DS46	E9E0L8	AAA family ATPase; Belongs to the AAA ATPase family.	Peroxisomal membrane anchor protein (Pex14), putative.	0.464
MAC_00119	MAC_03533	E9DS46	E9E0Y5	AAA family ATPase; Belongs to the AAA ATPase family.	SNF7 family protein.	0.764
MAC_00119	MAC_03578	E9DS46	E9E130	AAA family ATPase; Belongs to the AAA ATPase family.	Charged multivesicular body protein 3.	0.733
MAC_00119	MAC_03987	E9DS46	E9E289	AAA family ATPase; Belongs to the AAA ATPase family.	ESCRT-III component.	0.594
MAC_00119	MAC_04203	E9DS46	E9E2V5	AAA family ATPase; Belongs to the AAA ATPase family.	Putative peroxisomal targeting signal receptor.	0.410
MAC_00119	MAC_04797	E9DS46	E9E4J9	AAA family ATPase; Belongs to the AAA ATPase family.	Protein YOP1.	0.519
MAC_00119	MAC_05822	E9DS46	E9E7H4	AAA family ATPase; Belongs to the AAA ATPase family.	Putative chromatin modifying protein 1b.	0.693
MAC_00119	MAC_06222	E9DS46	E9E8K7	AAA family ATPase; Belongs to the AAA ATPase family.	Kelch repeat protein.	0.616
MAC_00119	MAC_07289	E9DS46	E9EBP1	AAA family ATPase; Belongs to the AAA ATPase family.	Pex13 protein.	0.451
MAC_00119	MAC_08185	E9DS46	E9EE87	AAA family ATPase; Belongs to the AAA ATPase family.	Vacuolar sorting protein SNF7 family protein, putative.	0.794
MAC_00119	MAC_08470	E9DS46	E9EF22	AAA family ATPase; Belongs to the AAA ATPase family.	Charged multivesicular body protein 3.	0.733
MAC_00119	MAC_09616	E9DS46	E9EIB8	AAA family ATPase; Belongs to the AAA ATPase family.	Senescence domain-containing protein.	0.618
MAC_00205	MAC_00119	E9DR36	E9DS46	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	AAA family ATPase; Belongs to the AAA ATPase family.	0.690
MAC_00205	MAC_00691	E9DR36	E9DSU3	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.991