(24 nodes) Multivesicular body sorting pathway, and VHS domain network (Metarhizium acridum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_00205	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family. (430 aa)
	MAC_00207	Endosome-associated ubiquitin isopeptidase (AmsH). (476 aa)
	MAC_00691	Uncharacterized protein. (299 aa)
	MAC_01273	Vacuolar protein sorting protein (Vps36), putative. (744 aa)
	MAC_01646	ESCRT-III component. (452 aa)
	MAC_01664	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (265 aa)
	MAC_01705	Uncharacterized protein. (212 aa)
	MAC_02211	pH-response regulator protein palA/RIM20. (934 aa)
	MAC_02468	Uncharacterized protein. (522 aa)
	MAC_02614	ESCRT-III component. (223 aa)
	MAC_02650	Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane. (755 aa)
	MAC_02651	Ubiquitin carboxyl-terminal hydrolase 2; Belongs to the peptidase C19 family. (1031 aa)
	MAC_02734	Transcription factor Rap1, putative. (706 aa)
	MAC_03432	Class E vacuolar protein-sorting machinery protein HSE1. (629 aa)
	MAC_03494	Vacuolar protein-sorting-associated protein. (195 aa)
	MAC_03533	SNF7 family protein. (199 aa)
	MAC_03578	Charged multivesicular body protein 3. (218 aa)
	MAC_03987	ESCRT-III component. (110 aa)
	MAC_05525	Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (238 aa)
	MAC_05822	Putative chromatin modifying protein 1b. (204 aa)
	MAC_06577	Uncharacterized protein. (362 aa)
	MAC_06773	Vacuolar protein-sorting protein BRO1. (994 aa)
	MAC_08185	Vacuolar sorting protein SNF7 family protein, putative. (455 aa)
	MAC_08470	Charged multivesicular body protein 3. (156 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00205	MAC_00691	E9DR36	E9DSU3	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.991
MAC_00205	MAC_01273	E9DR36	E9DUH5	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	Vacuolar protein sorting protein (Vps36), putative.	0.661
MAC_00205	MAC_01646	E9DR36	E9DVJ8	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	ESCRT-III component.	0.996
MAC_00205	MAC_01705	E9DR36	E9DVQ7	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.994
MAC_00205	MAC_02211	E9DR36	E9DX63	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	pH-response regulator protein palA/RIM20.	0.696
MAC_00205	MAC_02468	E9DR36	E9DXX0	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.700
MAC_00205	MAC_02614	E9DR36	E9DYB6	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	ESCRT-III component.	0.953
MAC_00205	MAC_02650	E9DR36	E9DYF3	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.	0.690
MAC_00205	MAC_02651	E9DR36	E9DYF4	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	Ubiquitin carboxyl-terminal hydrolase 2; Belongs to the peptidase C19 family.	0.538
MAC_00205	MAC_03494	E9DR36	E9E0U6	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	Vacuolar protein-sorting-associated protein.	0.610
MAC_00205	MAC_03533	E9DR36	E9E0Y5	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	SNF7 family protein.	0.997
MAC_00205	MAC_03578	E9DR36	E9E130	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	Charged multivesicular body protein 3.	0.866
MAC_00205	MAC_03987	E9DR36	E9E289	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	ESCRT-III component.	0.953
MAC_00205	MAC_05525	E9DR36	E9E6M7	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.702
MAC_00205	MAC_05822	E9DR36	E9E7H4	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	Putative chromatin modifying protein 1b.	0.998
MAC_00205	MAC_06577	E9DR36	E9E9M9	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.999
MAC_00205	MAC_06773	E9DR36	E9EA75	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	Vacuolar protein-sorting protein BRO1.	0.858
MAC_00205	MAC_08185	E9DR36	E9EE87	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	Vacuolar sorting protein SNF7 family protein, putative.	0.863
MAC_00205	MAC_08470	E9DR36	E9EF22	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	Charged multivesicular body protein 3.	0.866
MAC_00207	MAC_01646	E9DR38	E9DVJ8	Endosome-associated ubiquitin isopeptidase (AmsH).	ESCRT-III component.	0.783