(78 nodes) Mixed, incl. Protein localization to mitochondrion, and Mitochondrial calcium ion transport network (Metarhizium acridum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_00170	Mitochondrial import inner membrane translocase subunit TIM17. (145 aa)
	MAC_00380	Mitochondrial DnaJ chaperone (Tim14), putative. (105 aa)
	MAC_00393	PUM-HD domain-containing protein. (829 aa)
	MAC_00079	Intermembrane space AAA protease IAP-1. (740 aa)
	MAC_00101	Sulfhydryl oxidase. (193 aa)
	MAC_00654	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. (1085 aa)
	MAC_00721	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family. (678 aa)
	MAC_00784	Cytochrome c oxidase subunit 7A; This small integral protein plays a role in holoenzyme assembly or stability. (60 aa)
	MAC_00814	Uncharacterized protein. (386 aa)
	MAC_01003	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (275 aa)
	MAC_01160	Mitochondrial outer membrane 72kDa protein. (622 aa)
	MAC_01165	Outer mitochondrial membrane protein porin. (283 aa)
	MAC_01313	Chaperonin; Belongs to the GroES chaperonin family. (104 aa)
	PIM1	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (1118 aa)
	MAC_01497	DUF2263 domain-containing protein. (306 aa)
	MAC_01537	Outer membrane protein. (527 aa)
	MAC_01647	Mitochondrial import receptor subunit tom-22. (153 aa)
	MAC_01997	ATP-dependent Clp protease proteolytic subunit. (174 aa)
	MAC_02219	Uncharacterized protein. (274 aa)
	MAC_02354	Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family. (512 aa)
	MAC_02462	Cytochrome c oxidase assembly protein. (86 aa)
	MAC_02502	Mitochondrial import inner membrane translocase subunit tim23. (228 aa)
	MAC_02634	Cytochrome c oxidase assembly protein, putative. (473 aa)
	MAC_02684	RNA binding effector protein Scp160, putative. (1277 aa)
	MAC_02749	Stomatin family protein. (396 aa)
	MAC_03023	Cytochrome c oxidase copper chaperone Cox17, putative. (73 aa)
	MAC_03152	RNA binding protein Jsn1, putative. (1154 aa)
	MAC_03307	Uncharacterized protein. (242 aa)
	MAC_03308	Uncharacterized protein. (242 aa)
	MAC_03374	Mitochondrial import inner membrane translocase subunit TIM17. (194 aa)
	MAC_03768	Rhomboid family protein. (575 aa)
	MAC_03876	Peptide alpha-N-acetyltransferase. (245 aa)
	MAC_03883	MICOS complex subunit MIC12; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (282 aa)
	MAC_03807	Mitochondrial outer membrane protein (Sam35), putative. (311 aa)
	MAC_03952	Presequence translocated-associated motor subunit pam17. (267 aa)
	MAC_04186	Mitochondrial import inner membrane translocase subunit tim-54. (450 aa)
	MAC_04667	Mitochondrial import inner membrane translocase subunit Tim17 family protein. (207 aa)
	MAC_04794	Mitochondrial import inner membrane translocase subunit TIM16. (141 aa)
	MAC_04853	Cytochrome c oxidase assembly protein (Pet191), putative. (134 aa)
	MAC_04912	Mitochondrial import inner membrane translocase subunit TIM10. (96 aa)
	MAC_04994	Tim10/DDP family zinc finger containing protein. (88 aa)
	MAC_05227	Mitochondrial import receptor subunit TOM40. (377 aa)
	MAC_05282	Prohibitin. (330 aa)
	MAC_05334	Uncharacterized protein. (603 aa)
	MAC_05494	Cactin, putative. (505 aa)
	MAC_05674	RNA-binding protein, putative. (1012 aa)
	MAC_05934	Matrix AAA protease MAP-1. (904 aa)
	MAC_06044	Mitochondrial chaperone ATPase (Bcs1), putative; Belongs to the AAA ATPase family. (510 aa)
	MAC_06089	37S ribosomal protein Rsm22. (817 aa)
	MAC_06103	Mitochondrial chaperone BCS1. (116 aa)
	MAC_06410	Mitochondrial import receptor subunit tom-20. (196 aa)
	MAC_06469	Protein VTS. (570 aa)
	MAC_06578	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (535 aa)
	MAC_06662	Uncharacterized protein. (391 aa)
	MAC_06663	Protein sco1. (244 aa)
	MAC_06889	Mitochondrial genome maintenance protein Mgr2. (129 aa)
	MAC_07169	MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (92 aa)
	MAC_07208	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (241 aa)
	MAC_07223	Pumilio-family RNA binding repeat protein. (771 aa)
	MAC_07267	Metaxin, putative. (423 aa)
	MAC_07273	MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (655 aa)
	MAC_07310	Homeoprotein. (620 aa)
	MAC_07369	Intermembrane space import and assembly protein 40. (300 aa)
	MAC_07585	SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (460 aa)
	MAC_07587	CHCH domain protein. (222 aa)
	MAC_07803	Sulfhydryl oxidase. (236 aa)
	MAC_08052	Putative MCX1 protein. (575 aa)
	MAC_08267	Putative BCS1 protein; Belongs to the AAA ATPase family. (639 aa)
	MAC_08314	Mitochondrial inner membrane translocase subunit TIM44, putative. (538 aa)
	MAC_08432	Import inner membrane translocase subunit tim-21. (218 aa)
	MAC_08645	Mitochondrial import inner membrane translocase subunit TIM13; Belongs to the small Tim family. (85 aa)
	MAC_08669	Uncharacterized protein. (268 aa)
	MAC_08872	DUF2263 domain-containing protein. (299 aa)
	MAC_08873	Mitochondrial chaperone BCS1; Belongs to the AAA ATPase family. (464 aa)
	MAC_08939	Mitochondrial import inner membrane translocase subunit tim-22. (174 aa)
	MAC_09237	Prohibitin. (280 aa)
	MAC_09574	Heat shock protein 60 (Antigen HIS-62); Belongs to the chaperonin (HSP60) family. (584 aa)
	MAC_09726	Uncharacterized protein. (370 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00079	MAC_00654	E9DS06	E9DSQ6	Intermembrane space AAA protease IAP-1.	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family.	0.613
MAC_00079	MAC_00721	E9DS06	E9DSX3	Intermembrane space AAA protease IAP-1.	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	0.476
MAC_00079	MAC_01160	E9DS06	E9DU62	Intermembrane space AAA protease IAP-1.	Mitochondrial outer membrane 72kDa protein.	0.442
MAC_00079	MAC_01997	E9DS06	E9DWJ9	Intermembrane space AAA protease IAP-1.	ATP-dependent Clp protease proteolytic subunit.	0.603
MAC_00079	MAC_02502	E9DS06	E9DY04	Intermembrane space AAA protease IAP-1.	Mitochondrial import inner membrane translocase subunit tim23.	0.563
MAC_00079	MAC_02749	E9DS06	E9DYQ2	Intermembrane space AAA protease IAP-1.	Stomatin family protein.	0.771
MAC_00079	MAC_03768	E9DS06	E9E1M0	Intermembrane space AAA protease IAP-1.	Rhomboid family protein.	0.839
MAC_00079	MAC_04186	E9DS06	E9E2T8	Intermembrane space AAA protease IAP-1.	Mitochondrial import inner membrane translocase subunit tim-54.	0.521
MAC_00079	MAC_04912	E9DS06	E9E4W4	Intermembrane space AAA protease IAP-1.	Mitochondrial import inner membrane translocase subunit TIM10.	0.555
MAC_00079	MAC_04994	E9DS06	E9E5B8	Intermembrane space AAA protease IAP-1.	Tim10/DDP family zinc finger containing protein.	0.584
MAC_00079	MAC_05227	E9DS06	E9E5S9	Intermembrane space AAA protease IAP-1.	Mitochondrial import receptor subunit TOM40.	0.514
MAC_00079	MAC_05282	E9DS06	E9E5Y4	Intermembrane space AAA protease IAP-1.	Prohibitin.	0.771
MAC_00079	MAC_05934	E9DS06	E9E7T6	Intermembrane space AAA protease IAP-1.	Matrix AAA protease MAP-1.	0.462
MAC_00079	MAC_06410	E9DS06	E9E962	Intermembrane space AAA protease IAP-1.	Mitochondrial import receptor subunit tom-20.	0.452
MAC_00079	MAC_07208	E9DS06	E9EBG0	Intermembrane space AAA protease IAP-1.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.462
MAC_00079	MAC_07273	E9DS06	E9EBM5	Intermembrane space AAA protease IAP-1.	MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	0.433
MAC_00079	MAC_08052	E9DS06	E9EDU7	Intermembrane space AAA protease IAP-1.	Putative MCX1 protein.	0.764
MAC_00079	MAC_09237	E9DS06	E9EH89	Intermembrane space AAA protease IAP-1.	Prohibitin.	0.756
MAC_00079	MAC_09574	E9DS06	E9EI76	Intermembrane space AAA protease IAP-1.	Heat shock protein 60 (Antigen HIS-62); Belongs to the chaperonin (HSP60) family.	0.563
MAC_00079	PIM1	E9DS06	E9DUP3	Intermembrane space AAA protease IAP-1.	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.	0.650