(37 nodes) Valine, leucine and isoleucine degradation, and acyl-CoA oxidase activity network (Metarhizium acridum)

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	MAC_00631	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa)
	MAC_00682	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (430 aa)
	MAC_00832	Isovaleryl-CoA dehydrogenase. (401 aa)
	MAC_00833	Methylcrotonoyl-CoA carboxylase beta chain. (569 aa)
	MAC_01176	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (502 aa)
	MAC_01490	Glutaryl-CoA dehydrogenase. (427 aa)
	MAC_01492	Integral membrane protein. (397 aa)
	MAC_01637	Acetoacetyl-CoA synthase. (652 aa)
	MAC_02074	Acetoacetyl-CoA synthase. (724 aa)
	MAC_02697	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
	MAC_03481	Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (597 aa)
	MAC_03561	Nonspecific lipid-transfer protein; Belongs to the thiolase-like superfamily. Thiolase family. (459 aa)
	MAC_03793	Methylmalonate semialdehyde dehydrogenase. (575 aa)
	MAC_03827	Acetate-CoA ligase. (703 aa)
	MAC_03923	(R)-benzylsuccinyl-CoA dehydrogenase. (455 aa)
	MAC_04115	Acetoacetyl-CoA synthase. (735 aa)
	MAC_04702	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (519 aa)
	MAC_04770	Uncharacterized protein. (439 aa)
	MAC_04820	Uncharacterized protein. (575 aa)
	MAC_04821	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (324 aa)
	MAC_04866	Methylcrotonoyl-CoA carboxylase alpha chain. (673 aa)
	MAC_05128	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (683 aa)
	MAC_05656	Hydroxymethylglutaryl-CoA lyase. (407 aa)
	MAC_05794	3,2-trans-enoyl-CoA isomerase, putative. (286 aa)
	MAC_05814	3-hydroxyacyl-CoA dehydrogenase, putative. (973 aa)
	MAC_05937	3-hydroxybutyryl-CoA dehydrogenase. (213 aa)
	MAC_06608	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
	MAC_06925	Acyl-CoA oxidase, putative. (180 aa)
	MAC_07432	Methylglutaconyl-CoA hydratase, putative. (316 aa)
	MAC_07838	Enoyl-CoA hydratase/isomerase family protein. (153 aa)
	MAC_07892	Electron transfer flavoprotein alpha-subunit. (339 aa)
	MAC_07910	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (534 aa)
	MAC_07935	Electron transfer flavoprotein beta-subunit. (258 aa)
	MAC_08886	Arsenite efflux transporter, putative. (749 aa)
	MAC_08941	Integral membrane protein, putative. (179 aa)
	MAC_09283	Uncharacterized protein. (193 aa)
	MAC_09599	Enoyl-CoA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family. (294 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00631	MAC_00682	E9DSN3	E9DST4	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.727
MAC_00631	MAC_00832	E9DSN3	E9DTJ4	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Isovaleryl-CoA dehydrogenase.	0.949
MAC_00631	MAC_00833	E9DSN3	E9DTJ5	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Methylcrotonoyl-CoA carboxylase beta chain.	0.955
MAC_00631	MAC_01176	E9DSN3	E9DU78	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.757
MAC_00631	MAC_01490	E9DSN3	E9DUV7	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Glutaryl-CoA dehydrogenase.	0.958
MAC_00631	MAC_01492	E9DSN3	E9DUV9	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Integral membrane protein.	0.428
MAC_00631	MAC_01637	E9DSN3	E9DVI9	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Acetoacetyl-CoA synthase.	0.426
MAC_00631	MAC_02074	E9DSN3	E9DWS6	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Acetoacetyl-CoA synthase.	0.426
MAC_00631	MAC_02697	E9DSN3	E9DYK0	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.757
MAC_00631	MAC_03481	E9DSN3	E9E0T3	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.	0.400
MAC_00631	MAC_03561	E9DSN3	E9E113	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Nonspecific lipid-transfer protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.740
MAC_00631	MAC_03827	E9DSN3	E9E1X2	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Acetate-CoA ligase.	0.476
MAC_00631	MAC_03923	E9DSN3	E9E225	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	(R)-benzylsuccinyl-CoA dehydrogenase.	0.923
MAC_00631	MAC_04115	E9DSN3	E9E2L7	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Acetoacetyl-CoA synthase.	0.426
MAC_00631	MAC_04702	E9DSN3	E9E4A4	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.429
MAC_00631	MAC_04770	E9DSN3	E9E4H2	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Uncharacterized protein.	0.951
MAC_00631	MAC_04820	E9DSN3	E9E4M2	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Uncharacterized protein.	0.733
MAC_00631	MAC_04821	E9DSN3	E9E4M3	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.733
MAC_00631	MAC_04866	E9DSN3	E9E4R8	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Methylcrotonoyl-CoA carboxylase alpha chain.	0.939
MAC_00631	MAC_05128	E9DSN3	E9E5I0	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.958