node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MAC_01609 | MAC_02545 | E9DVG1 | E9DY47 | BRCT domain-containing protein. | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability. | 0.866 |
MAC_01609 | MAC_03495 | E9DVG1 | E9E0U7 | BRCT domain-containing protein. | BRCT domain-containing protein. | 0.948 |
MAC_01609 | MAC_07645 | E9DVG1 | E9ECP7 | BRCT domain-containing protein. | BRCT domain-containing protein. | 0.883 |
MAC_01609 | MAC_07862 | E9DVG1 | E9EDB4 | BRCT domain-containing protein. | DNA damage repair protein (Rad9), putative. | 0.995 |
MAC_01609 | MAC_09543 | E9DVG1 | E9EI45 | BRCT domain-containing protein. | DNA repaire protein UVS6. | 0.783 |
MAC_01609 | MAC_09589 | E9DVG1 | E9EI91 | BRCT domain-containing protein. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.701 |
MAC_02545 | MAC_01609 | E9DY47 | E9DVG1 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability. | BRCT domain-containing protein. | 0.866 |
MAC_02545 | MAC_03495 | E9DY47 | E9E0U7 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability. | BRCT domain-containing protein. | 0.965 |
MAC_02545 | MAC_07645 | E9DY47 | E9ECP7 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability. | BRCT domain-containing protein. | 0.904 |
MAC_02545 | MAC_07862 | E9DY47 | E9EDB4 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability. | DNA damage repair protein (Rad9), putative. | 0.966 |
MAC_02545 | MAC_09543 | E9DY47 | E9EI45 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability. | DNA repaire protein UVS6. | 0.980 |
MAC_02545 | MAC_09589 | E9DY47 | E9EI91 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.987 |
MAC_03495 | MAC_01609 | E9E0U7 | E9DVG1 | BRCT domain-containing protein. | BRCT domain-containing protein. | 0.948 |
MAC_03495 | MAC_02545 | E9E0U7 | E9DY47 | BRCT domain-containing protein. | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability. | 0.965 |
MAC_03495 | MAC_07645 | E9E0U7 | E9ECP7 | BRCT domain-containing protein. | BRCT domain-containing protein. | 0.781 |
MAC_03495 | MAC_07862 | E9E0U7 | E9EDB4 | BRCT domain-containing protein. | DNA damage repair protein (Rad9), putative. | 0.974 |
MAC_03495 | MAC_09543 | E9E0U7 | E9EI45 | BRCT domain-containing protein. | DNA repaire protein UVS6. | 0.852 |
MAC_03495 | MAC_09589 | E9E0U7 | E9EI91 | BRCT domain-containing protein. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.868 |
MAC_07645 | MAC_01609 | E9ECP7 | E9DVG1 | BRCT domain-containing protein. | BRCT domain-containing protein. | 0.883 |
MAC_07645 | MAC_02545 | E9ECP7 | E9DY47 | BRCT domain-containing protein. | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability. | 0.904 |