(44 nodes) Neddylation, and COP9 signalosome network (Metarhizium acridum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_00027	Putative myocyte-specific enhancer factor 2d. (476 aa)
	MAC_00582	F-box domain containing protein. (521 aa)
	MAC_00874	Uncharacterized protein. (215 aa)
	MAC_01259	DNA damage-binding protein 1. (1121 aa)
	MAC_01608	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (342 aa)
	MAC_01706	F-box/WD-40 repeat-containing protein. (1008 aa)
	MAC_01896	RING-A protein. (103 aa)
	MAC_02102	WD domain protein. (740 aa)
	MAC_02547	Ubiquitin ligase subunit CulD; Belongs to the cullin family. (835 aa)
	MAC_03079	PCI domain containing protein. (419 aa)
	MAC_03119	SCF complex subunit Skp1; Belongs to the SKP1 family. (171 aa)
	MAC_03288	Uncharacterized protein. (222 aa)
	MAC_03819	E2 ubiquitin-conjugating enzyme. (113 aa)
	MAC_03914	Ubiquitin conjugating enzyme (UbcC), putative. (227 aa)
	MAC_03955	Ulp1 protease family protein. (251 aa)
	MAC_04094	COP9 signalosome subunit 1 (CsnA), putative. (453 aa)
	MAC_04335	COP9 signalosome complex subunit 3. (489 aa)
	MAC_04377	Uncharacterized protein. (362 aa)
	MAC_04706	F-box domain-containing protein. (564 aa)
	MAC_05060	WD domain and F-box domain containing protein. (679 aa)
	MAC_05281	NEDD8-like protein (RubA). (545 aa)
	MAC_05352	WD domain, G-beta repeat containing protein. (161 aa)
	MAC_05426	COP9 signalosome complex subunit 5. (335 aa)
	MAC_05563	F-box domain-containing protein. (751 aa)
	MAC_06012	Cullin binding protein CanA. (1374 aa)
	MAC_06872	COP9 signalosome subunit 2 (CsnB), putative. (508 aa)
	MAC_07003	WD repeat containing protein. (514 aa)
	MAC_07010	Sterol 3-beta-glucosyltransferase; Belongs to the glycosyltransferase 28 family. (1454 aa)
	MAC_07598	WD repeat protein. (639 aa)
	MAC_07617	COP9 signalosome subunit 7 (CsnG). (282 aa)
	MAC_07750	Uncharacterized protein. (472 aa)
	MAC_08080	Cullin; Belongs to the cullin family. (700 aa)
	MAC_08138	Putative cullulin 3; Belongs to the cullin family. (862 aa)
	MAC_08193	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme. (475 aa)
	MAC_08438	WD repeat-containing protein, putative; Belongs to the cullin family. (1148 aa)
	MAC_08539	WD repeat containing protein pop1. (1065 aa)
	MAC_08816	NEDD8-activating enzyme E1 catalytic subunit. (393 aa)
	MAC_09244	Extracellular lipase, putative. (168 aa)
	MAC_09345	Uncharacterized protein. (518 aa)
	MAC_09421	COP9 signalosome subunit 6 (CsnF), putative. (418 aa)
	MAC_09532	F-box and WD40 domain protein, putative. (693 aa)
	MAC_09759	F-box domain-containing protein. (559 aa)
	MAC_09760	F-box domain-containing protein. (563 aa)
	MAC_09849	Uncharacterized protein. (199 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00027	MAC_01259	E9DRV4	E9DUG1	Putative myocyte-specific enhancer factor 2d.	DNA damage-binding protein 1.	0.964
MAC_00027	MAC_01896	E9DRV4	E9DW98	Putative myocyte-specific enhancer factor 2d.	RING-A protein.	0.649
MAC_00027	MAC_02102	E9DRV4	E9DWV4	Putative myocyte-specific enhancer factor 2d.	WD domain protein.	0.613
MAC_00027	MAC_02547	E9DRV4	E9DY49	Putative myocyte-specific enhancer factor 2d.	Ubiquitin ligase subunit CulD; Belongs to the cullin family.	0.814
MAC_00027	MAC_03079	E9DRV4	E9DZN1	Putative myocyte-specific enhancer factor 2d.	PCI domain containing protein.	0.646
MAC_00027	MAC_03288	E9DRV4	E9E0A7	Putative myocyte-specific enhancer factor 2d.	Uncharacterized protein.	0.615
MAC_00027	MAC_04094	E9DRV4	E9E2J6	Putative myocyte-specific enhancer factor 2d.	COP9 signalosome subunit 1 (CsnA), putative.	0.641
MAC_00027	MAC_04335	E9DRV4	E9E387	Putative myocyte-specific enhancer factor 2d.	COP9 signalosome complex subunit 3.	0.681
MAC_00027	MAC_05352	E9DRV4	E9E654	Putative myocyte-specific enhancer factor 2d.	WD domain, G-beta repeat containing protein.	0.516
MAC_00027	MAC_05426	E9DRV4	E9E6C8	Putative myocyte-specific enhancer factor 2d.	COP9 signalosome complex subunit 5.	0.646
MAC_00027	MAC_06872	E9DRV4	E9EAH4	Putative myocyte-specific enhancer factor 2d.	COP9 signalosome subunit 2 (CsnB), putative.	0.694
MAC_00027	MAC_07003	E9DRV4	E9EAV5	Putative myocyte-specific enhancer factor 2d.	WD repeat containing protein.	0.759
MAC_00027	MAC_07598	E9DRV4	E9ECK0	Putative myocyte-specific enhancer factor 2d.	WD repeat protein.	0.516
MAC_00027	MAC_07617	E9DRV4	E9ECL9	Putative myocyte-specific enhancer factor 2d.	COP9 signalosome subunit 7 (CsnG).	0.478
MAC_00027	MAC_09421	E9DRV4	E9EHS3	Putative myocyte-specific enhancer factor 2d.	COP9 signalosome subunit 6 (CsnF), putative.	0.680
MAC_00027	MAC_09849	E9DRV4	E9EJ01	Putative myocyte-specific enhancer factor 2d.	Uncharacterized protein.	0.615
MAC_00582	MAC_00874	E9DSI4	E9DTN6	F-box domain containing protein.	Uncharacterized protein.	0.798
MAC_00582	MAC_01896	E9DSI4	E9DW98	F-box domain containing protein.	RING-A protein.	0.626
MAC_00582	MAC_03119	E9DSI4	E9DZS1	F-box domain containing protein.	SCF complex subunit Skp1; Belongs to the SKP1 family.	0.920
MAC_00582	MAC_03819	E9DSI4	E9E1W4	F-box domain containing protein.	E2 ubiquitin-conjugating enzyme.	0.645