(24 nodes) Mixed, incl. SCF ubiquitin ligase complex, and Protein neddylation network (Metarhizium acridum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_00582	F-box domain containing protein. (521 aa)
	MAC_00874	Uncharacterized protein. (215 aa)
	MAC_01608	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (342 aa)
	MAC_01706	F-box/WD-40 repeat-containing protein. (1008 aa)
	MAC_01896	RING-A protein. (103 aa)
	MAC_03119	SCF complex subunit Skp1; Belongs to the SKP1 family. (171 aa)
	MAC_03819	E2 ubiquitin-conjugating enzyme. (113 aa)
	MAC_03914	Ubiquitin conjugating enzyme (UbcC), putative. (227 aa)
	MAC_03955	Ulp1 protease family protein. (251 aa)
	MAC_04377	Uncharacterized protein. (362 aa)
	MAC_04706	F-box domain-containing protein. (564 aa)
	MAC_05060	WD domain and F-box domain containing protein. (679 aa)
	MAC_05281	NEDD8-like protein (RubA). (545 aa)
	MAC_05563	F-box domain-containing protein. (751 aa)
	MAC_06012	Cullin binding protein CanA. (1374 aa)
	MAC_07750	Uncharacterized protein. (472 aa)
	MAC_08080	Cullin; Belongs to the cullin family. (700 aa)
	MAC_08138	Putative cullulin 3; Belongs to the cullin family. (862 aa)
	MAC_08193	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme. (475 aa)
	MAC_08438	WD repeat-containing protein, putative; Belongs to the cullin family. (1148 aa)
	MAC_08539	WD repeat containing protein pop1. (1065 aa)
	MAC_08816	NEDD8-activating enzyme E1 catalytic subunit. (393 aa)
	MAC_09244	Extracellular lipase, putative. (168 aa)
	MAC_09532	F-box and WD40 domain protein, putative. (693 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00582	MAC_00874	E9DSI4	E9DTN6	F-box domain containing protein.	Uncharacterized protein.	0.798
MAC_00582	MAC_01896	E9DSI4	E9DW98	F-box domain containing protein.	RING-A protein.	0.626
MAC_00582	MAC_03119	E9DSI4	E9DZS1	F-box domain containing protein.	SCF complex subunit Skp1; Belongs to the SKP1 family.	0.920
MAC_00582	MAC_03819	E9DSI4	E9E1W4	F-box domain containing protein.	E2 ubiquitin-conjugating enzyme.	0.645
MAC_00582	MAC_04377	E9DSI4	E9E3C9	F-box domain containing protein.	Uncharacterized protein.	0.882
MAC_00582	MAC_05281	E9DSI4	E9E5Y3	F-box domain containing protein.	NEDD8-like protein (RubA).	0.714
MAC_00582	MAC_07750	E9DSI4	E9ED02	F-box domain containing protein.	Uncharacterized protein.	0.882
MAC_00582	MAC_08080	E9DSI4	E9EDY2	F-box domain containing protein.	Cullin; Belongs to the cullin family.	0.855
MAC_00582	MAC_08138	E9DSI4	E9EE40	F-box domain containing protein.	Putative cullulin 3; Belongs to the cullin family.	0.855
MAC_00582	MAC_08438	E9DSI4	E9EEZ0	F-box domain containing protein.	WD repeat-containing protein, putative; Belongs to the cullin family.	0.771
MAC_00582	MAC_09244	E9DSI4	E9EH96	F-box domain containing protein.	Extracellular lipase, putative.	0.798
MAC_00874	MAC_00582	E9DTN6	E9DSI4	Uncharacterized protein.	F-box domain containing protein.	0.798
MAC_00874	MAC_01608	E9DTN6	E9DVG0	Uncharacterized protein.	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.	0.400
MAC_00874	MAC_01706	E9DTN6	E9DVQ8	Uncharacterized protein.	F-box/WD-40 repeat-containing protein.	0.662
MAC_00874	MAC_01896	E9DTN6	E9DW98	Uncharacterized protein.	RING-A protein.	0.821
MAC_00874	MAC_03819	E9DTN6	E9E1W4	Uncharacterized protein.	E2 ubiquitin-conjugating enzyme.	0.515
MAC_00874	MAC_03914	E9DTN6	E9E216	Uncharacterized protein.	Ubiquitin conjugating enzyme (UbcC), putative.	0.423
MAC_00874	MAC_05060	E9DTN6	E9E591	Uncharacterized protein.	WD domain and F-box domain containing protein.	0.499
MAC_00874	MAC_05281	E9DTN6	E9E5Y3	Uncharacterized protein.	NEDD8-like protein (RubA).	0.704
MAC_00874	MAC_05563	E9DTN6	E9E6R5	Uncharacterized protein.	F-box domain-containing protein.	0.491