STRINGSTRING
MAC_02545 MAC_02545 MAC_07986 MAC_07986 MAC_07862 MAC_07862 MAC_07613 MAC_07613 MAC_05535 MAC_05535 MAC_05001 MAC_05001 MAC_04722 MAC_04722 MAC_04304 MAC_04304 MAC_04133 MAC_04133 MAC_03935 MAC_03935 MAC_03915 MAC_03915 MAC_03174 MAC_03174 MAC_03088 MAC_03088 MAC_02830 MAC_02830 MAC_09664 MAC_09664 MAC_09589 MAC_09589 MAC_08581 MAC_08581 MAC_00683 MAC_00683 MAC_01056 MAC_01056 MAC_01609 MAC_01609 MAC_01667 MAC_01667
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAC_02545Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability. (2887 aa)
MAC_07986Coiled-coil domain-containing protein 16. (399 aa)
MAC_07862DNA damage repair protein (Rad9), putative. (1003 aa)
MAC_07613Serine/threonine protein kinase, putative. (535 aa)
MAC_05535DNA repair protein Rad1, putative. (115 aa)
MAC_05001Serine/threonine protein kinase, putative. (354 aa)
MAC_04722Protein kinase domain-containing protein. (490 aa)
MAC_04304MRC1 domain-containing protein. (1278 aa)
MAC_04133Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (502 aa)
MAC_03935Checkpoint protein; Belongs to the HUS1 family. (279 aa)
MAC_03915Protein kinase (Gcn2), putative. (1595 aa)
MAC_03174Protein kinase, putative. (1187 aa)
MAC_03088Cell cycle checkpoint protein RAD17. (1352 aa)
MAC_02830Serine/threonine protein kinase. (237 aa)
MAC_09664Alpha-1,2-mannosyltransferase (Alg2), putative. (693 aa)
MAC_09589Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (748 aa)
MAC_08581CAMK family protein kinase. (604 aa)
MAC_00683Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family. (351 aa)
MAC_01056Checkpoint kinase 2-like protein. (662 aa)
MAC_01609BRCT domain-containing protein. (855 aa)
MAC_01667DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (423 aa)
Your Current Organism:
Metarhizium acridum
NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102
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