STRINGSTRING
MAC_00126 MAC_00126 MAC_00127 MAC_00127 MAC_00502 MAC_00502 MAC_01474 MAC_01474 MAC_02515 MAC_02515 MAC_04133 MAC_04133 MAC_07584 MAC_07584 MAC_07885 MAC_07885 MAC_08510 MAC_08510 MAC_09124 MAC_09124
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAC_00126Histone H2B; Belongs to the histone H2B family. (137 aa)
MAC_00127Histone H2A; Belongs to the histone H2A family. (135 aa)
MAC_00502Uncharacterized protein. (192 aa)
MAC_01474Histone H1. (202 aa)
MAC_02515Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
MAC_04133Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (502 aa)
MAC_07584CENP-T_C domain-containing protein. (490 aa)
MAC_07885DUF2236 domain-containing protein. (378 aa)
MAC_08510Histone H2A; Belongs to the histone H2A family. (143 aa)
MAC_09124Histone H3; Belongs to the histone H3 family. (136 aa)
Your Current Organism:
Metarhizium acridum
NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.