(40 nodes) Negative regulation of signal transduction network (Metarhizium acridum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

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protein homology

Your Input:
	MAC_07461	GTPase-activator protein for Ras-like GTPase containing protein. (1109 aa)
	MAC_07486	Putative nitrogen permease regulator. (411 aa)
	MAC_08006	Uncharacterized protein. (263 aa)
	MAC_08661	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (325 aa)
	MAC_08412	TRI14-like protein. (357 aa)
	MAC_09072	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (473 aa)
	MAC_09616	Senescence domain-containing protein. (513 aa)
	MAC_00292	WD domain containing protein. (348 aa)
	MAC_00683	Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family. (351 aa)
	MAC_00794	G-protein beta subunit. (279 aa)
	MAC_01131	G protein alpha subunit. (354 aa)
	MAC_01205	TRI14-like protein. (345 aa)
	MAC_01291	Regulator of G protein signaling pathway. (700 aa)
	MAC_01364	FNIP_N domain-containing protein. (1191 aa)
	MAC_01645	Putative phosphoprotein phosphatase 2C. (589 aa)
	MAC_01715	Uncharacterized protein. (242 aa)
	MAC_01823	Uncharacterized protein. (489 aa)
	MAC_02185	Uncharacterized protein. (393 aa)
	MAC_02875	Cytochrome P450, putative. (451 aa)
	MAC_02973	Putative cytokinesis inhibitor byr4. (1021 aa)
	MAC_03052	Oxidoreductase, putative. (650 aa)
	MAC_03671	Protein kinase domain protein. (345 aa)
	MAC_03678	Protein-tyrosine phosphatase, putative. (815 aa)
	MAC_03915	Protein kinase (Gcn2), putative. (1595 aa)
	MAC_03971	C2 domain containing protein. (605 aa)
	MAC_04129	FHA domain containing protein. (596 aa)
	MAC_04165	Putative GTPase-activating protein of the rho/rac family (LRG1 protein). (1118 aa)
	MAC_04242	Mitotic check point protein (Bub2), putative. (441 aa)
	MAC_04247	RhoGAP domain protein. (1313 aa)
	MAC_04276	Uncharacterized protein. (229 aa)
	MAC_05091	Uncharacterized protein. (238 aa)
	MAC_05107	Tuberin. (1595 aa)
	MAC_05518	Bax Inhibitor family protein; Belongs to the BI1 family. (341 aa)
	MAC_05551	G protein alpha subunit. (360 aa)
	MAC_05665	Uncharacterized protein. (1972 aa)
	MAC_05706	Integral membrane protein, Mpv17/PMP22 family, putative; Belongs to the peroxisomal membrane protein PXMP2/4 family. (248 aa)
	MAC_06732	Hamartin. (1374 aa)
	MAC_07013	NADH:ubiquinone oxidoreductase 14kD subunit. (162 aa)
	MAC_07141	Proline racemase, putative. (1154 aa)
	MAC_07162	Uncharacterized protein. (505 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00683	MAC_04129	E9DST5	E9E2N1	Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family.	FHA domain containing protein.	0.402
MAC_00794	MAC_03915	E9DTF6	E9E217	G-protein beta subunit.	Protein kinase (Gcn2), putative.	0.561
MAC_01131	MAC_01291	E9DU33	E9DUJ3	G protein alpha subunit.	Regulator of G protein signaling pathway.	0.878
MAC_01131	MAC_01823	E9DU33	E9DW25	G protein alpha subunit.	Uncharacterized protein.	0.642
MAC_01291	MAC_01131	E9DUJ3	E9DU33	Regulator of G protein signaling pathway.	G protein alpha subunit.	0.878
MAC_01291	MAC_05551	E9DUJ3	E9E6Q3	Regulator of G protein signaling pathway.	G protein alpha subunit.	0.878
MAC_01645	MAC_03678	E9DVJ7	E9E1D0	Putative phosphoprotein phosphatase 2C.	Protein-tyrosine phosphatase, putative.	0.443
MAC_01823	MAC_01131	E9DW25	E9DU33	Uncharacterized protein.	G protein alpha subunit.	0.642
MAC_01823	MAC_05551	E9DW25	E9E6Q3	Uncharacterized protein.	G protein alpha subunit.	0.642
MAC_02973	MAC_04242	E9DZC5	E9E2Z4	Putative cytokinesis inhibitor byr4.	Mitotic check point protein (Bub2), putative.	0.870
MAC_03678	MAC_01645	E9E1D0	E9DVJ7	Protein-tyrosine phosphatase, putative.	Putative phosphoprotein phosphatase 2C.	0.443
MAC_03915	MAC_00794	E9E217	E9DTF6	Protein kinase (Gcn2), putative.	G-protein beta subunit.	0.561
MAC_04129	MAC_00683	E9E2N1	E9DST5	FHA domain containing protein.	Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family.	0.402
MAC_04129	MAC_04242	E9E2N1	E9E2Z4	FHA domain containing protein.	Mitotic check point protein (Bub2), putative.	0.650
MAC_04165	MAC_04247	E9E2R7	E9E2Z9	Putative GTPase-activating protein of the rho/rac family (LRG1 protein).	RhoGAP domain protein.	0.589
MAC_04242	MAC_02973	E9E2Z4	E9DZC5	Mitotic check point protein (Bub2), putative.	Putative cytokinesis inhibitor byr4.	0.870
MAC_04242	MAC_04129	E9E2Z4	E9E2N1	Mitotic check point protein (Bub2), putative.	FHA domain containing protein.	0.650
MAC_04242	MAC_09072	E9E2Z4	E9EGS4	Mitotic check point protein (Bub2), putative.	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.952
MAC_04247	MAC_04165	E9E2Z9	E9E2R7	RhoGAP domain protein.	Putative GTPase-activating protein of the rho/rac family (LRG1 protein).	0.589
MAC_05107	MAC_06732	E9E5F9	E9EA34	Tuberin.	Hamartin.	0.951