(37 nodes) Terpenoid biosynthetic process network (Metarhizium acridum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_08210	Geranylgeranyl pyrophosphate synthetase AtmG; Belongs to the FPP/GGPP synthase family. (331 aa)
	MAC_09801	Actin patch protein. (822 aa)
	MAC_09696	DUF2236 domain-containing protein. (403 aa)
	MAC_09499	LysR family regulatory protein, putative. (449 aa)
	MAC_09402	GNAT family N-acetyltransferase, putative. (179 aa)
	MAC_09061	Decaprenyl-diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family. (449 aa)
	MAC_08757	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (407 aa)
	MAC_08534	Trichodiene oxygenase. (520 aa)
	MAC_08439	Short-chain dehydrogenase/reductase family protein, putative. (344 aa)
	MAC_08209	UbiA prenyltransferase family protein. (347 aa)
	MAC_08208	Integral membrane protein. (173 aa)
	MAC_07569	Benzoate 4-monooxygenase cytochrome P450. (492 aa)
	MAC_07199	Uncharacterized protein. (403 aa)
	MAC_06941	Geranylgeranyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (325 aa)
	MAC_06940	Uncharacterized protein. (238 aa)
	MAC_06939	Prenyl transferase; Belongs to the FPP/GGPP synthase family. (341 aa)
	MAC_06387	Uncharacterized protein. (353 aa)
	MAC_06344	Aristolochene Synthase. (194 aa)
	MAC_06252	Toxin biosynthesis protein, putative. (414 aa)
	MAC_05978	Farnesyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. (347 aa)
	MAC_05964	Uncharacterized protein. (282 aa)
	MAC_05837	GA4 desaturase. (406 aa)
	MAC_05833	Peptidoglycan binding domain containing protein. (415 aa)
	MAC_05743	Farnesyl pyrophosphate synthetase 1. (248 aa)
	MAC_05371	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (723 aa)
	MAC_05219	Short-chain dehydrogenase, putative. (334 aa)
	MAC_04731	Uncharacterized protein. (187 aa)
	MAC_04069	Oxidosqualene:lanosterol cyclase; Belongs to the terpene cyclase/mutase family. (1227 aa)
	MAC_04027	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (517 aa)
	MAC_03864	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (534 aa)
	MAC_03674	Uncharacterized protein. (506 aa)
	MAC_03516	Toxin biosynthesis protein, putative. (419 aa)
	MAC_03418	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (449 aa)
	MAC_02756	GNAT family N-acetyltransferase, putative. (194 aa)
	MAC_02619	Geranylgeranyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (429 aa)
	MAC_00673	Phosphomevalonate kinase. (414 aa)
	MAC_00651	Isopentenyl-diphosphate delta-isomerase. (258 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00651	MAC_00673	E9DSQ3	E9DSS5	Isopentenyl-diphosphate delta-isomerase.	Phosphomevalonate kinase.	0.646
MAC_00651	MAC_02619	E9DSQ3	E9DYC1	Isopentenyl-diphosphate delta-isomerase.	Geranylgeranyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.	0.959
MAC_00651	MAC_03418	E9DSQ3	E9E0M0	Isopentenyl-diphosphate delta-isomerase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.876
MAC_00651	MAC_04069	E9DSQ3	E9E2H1	Isopentenyl-diphosphate delta-isomerase.	Oxidosqualene:lanosterol cyclase; Belongs to the terpene cyclase/mutase family.	0.865
MAC_00651	MAC_05371	E9DSQ3	E9E673	Isopentenyl-diphosphate delta-isomerase.	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	0.865
MAC_00651	MAC_05743	E9DSQ3	E9E795	Isopentenyl-diphosphate delta-isomerase.	Farnesyl pyrophosphate synthetase 1.	0.983
MAC_00651	MAC_05978	E9DSQ3	E9E7Y0	Isopentenyl-diphosphate delta-isomerase.	Farnesyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.	0.983
MAC_00651	MAC_06344	E9DSQ3	E9E8Z6	Isopentenyl-diphosphate delta-isomerase.	Aristolochene Synthase.	0.573
MAC_00651	MAC_06939	E9DSQ3	E9EAP1	Isopentenyl-diphosphate delta-isomerase.	Prenyl transferase; Belongs to the FPP/GGPP synthase family.	0.614
MAC_00651	MAC_06941	E9DSQ3	E9EAP3	Isopentenyl-diphosphate delta-isomerase.	Geranylgeranyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.	0.955
MAC_00651	MAC_08209	E9DSQ3	E9EEB1	Isopentenyl-diphosphate delta-isomerase.	UbiA prenyltransferase family protein.	0.818
MAC_00651	MAC_08210	E9DSQ3	E9EEB2	Isopentenyl-diphosphate delta-isomerase.	Geranylgeranyl pyrophosphate synthetase AtmG; Belongs to the FPP/GGPP synthase family.	0.959
MAC_00651	MAC_08757	E9DSQ3	E9EFV9	Isopentenyl-diphosphate delta-isomerase.	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	0.818
MAC_00651	MAC_09061	E9DSQ3	E9EGR3	Isopentenyl-diphosphate delta-isomerase.	Decaprenyl-diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family.	0.795
MAC_00673	MAC_00651	E9DSS5	E9DSQ3	Phosphomevalonate kinase.	Isopentenyl-diphosphate delta-isomerase.	0.646
MAC_00673	MAC_03418	E9DSS5	E9E0M0	Phosphomevalonate kinase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.655
MAC_00673	MAC_04069	E9DSS5	E9E2H1	Phosphomevalonate kinase.	Oxidosqualene:lanosterol cyclase; Belongs to the terpene cyclase/mutase family.	0.476
MAC_00673	MAC_05371	E9DSS5	E9E673	Phosphomevalonate kinase.	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	0.476
MAC_00673	MAC_05743	E9DSS5	E9E795	Phosphomevalonate kinase.	Farnesyl pyrophosphate synthetase 1.	0.485
MAC_00673	MAC_05978	E9DSS5	E9E7Y0	Phosphomevalonate kinase.	Farnesyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.	0.485