(45 nodes) Filamentous growth network (Metarhizium acridum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_00098	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
	MAC_00687	SAGA-like transcriptional regulatory complex subunit Spt3. (300 aa)
	MAC_00699	C6 finger domain protein, putative. (658 aa)
	MAC_00794	G-protein beta subunit. (279 aa)
	MAC_00841	Uncharacterized protein. (249 aa)
	MAC_01053	Histidine kinase 1. (1293 aa)
	MAC_01268	Ion_trans domain-containing protein. (682 aa)
	MAC_01635	MAPKKK cascade protein kinase regulator Ste50. (436 aa)
	MAC_01807	Small GTPase-binding protein. (194 aa)
	MAC_01831	Putative actin-interacting protein AIP3. (1001 aa)
	MAC_02020	Putative histidine kinase HHK1p. (2549 aa)
	MAC_02493	Uncharacterized protein. (592 aa)
	MAC_02597	Oxysterol binding protein (Osh3), putative. (982 aa)
	MAC_02685	Non-specific serine/threonine protein kinase. (848 aa)
	MAC_02720	Spermine/spermidine synthase. (587 aa)
	MAC_02795	Nonselective cation channel. (654 aa)
	MAC_02807	Glucoamylase. (575 aa)
	MAC_03153	Non-specific serine/threonine protein kinase. (802 aa)
	MAC_03438	Ccr4-Not transcription complex subunit (NOT1), putative. (2184 aa)
	MAC_03500	N-acetylglucosamine-6-phosphate deacetylase. (446 aa)
	uba4	Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (454 aa)
	MAC_04024	Fungal specific transcription factor domain protein. (287 aa)
	MAC_04959	Protein RHO1. (153 aa)
	MAC_05029	MAP kinase kinase kinase Ste11. (902 aa)
	MAC_05061	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (408 aa)
	MAC_05067	Cell division control protein. (294 aa)
	MAC_06035	Phosphoinositide phospholipase C. (1153 aa)
	MAC_06069	Uncharacterized protein. (147 aa)
	MAC_06259	C6 transcription factor, putative. (652 aa)
	MAC_06429	Cation channel family transporter, putative. (1126 aa)
	MAC_07174	Phosphoinositide phospholipase C. (648 aa)
	MAC_07188	UDENN domain-containing protein. (845 aa)
	MAC_07255	Polysaccharide synthase Cps1, putative. (489 aa)
	MAC_07761	Uncharacterized protein. (640 aa)
	MAC_07801	Putative cell surface flocculin. (840 aa)
	MAC_08358	Phosphoinositide phospholipase C. (648 aa)
	MAC_08387	RHOMBOID-like protein. (500 aa)
	MAC_08516	GTPase activating protein (BUD2/CLA2). (1265 aa)
	MAC_08749	Conidiophore development protein hymA. (380 aa)
	MAC_08967	Protein phosphatase-1, putative. (454 aa)
	MAC_09271	C6 zinc finger domain-containing protein. (444 aa)
	MAC_09390	SAGA-like transcriptional regulatory complex subunit Spt3, putative. (308 aa)
	MAC_09510	Phosphoinositide phospholipase C. (584 aa)
	MAC_09546	Amidase. (614 aa)
	MAC_09829	C6 transcription factor. (425 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00098	MAC_00794	E9DS25	E9DTF6	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	G-protein beta subunit.	0.475
MAC_00098	MAC_01635	E9DS25	E9DVI7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	MAPKKK cascade protein kinase regulator Ste50.	0.603
MAC_00098	MAC_02685	E9DS25	E9DYI8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Non-specific serine/threonine protein kinase.	0.568
MAC_00098	MAC_03153	E9DS25	E9DZV5	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Non-specific serine/threonine protein kinase.	0.511
MAC_00098	MAC_05029	E9DS25	E9E560	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	MAP kinase kinase kinase Ste11.	0.858
MAC_00098	MAC_05067	E9DS25	E9E598	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Cell division control protein.	0.547
MAC_00794	MAC_00098	E9DTF6	E9DS25	G-protein beta subunit.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.475
MAC_01635	MAC_00098	E9DVI7	E9DS25	MAPKKK cascade protein kinase regulator Ste50.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.603
MAC_01635	MAC_05029	E9DVI7	E9E560	MAPKKK cascade protein kinase regulator Ste50.	MAP kinase kinase kinase Ste11.	0.994
MAC_01635	MAC_05067	E9DVI7	E9E598	MAPKKK cascade protein kinase regulator Ste50.	Cell division control protein.	0.966
MAC_01807	MAC_02685	E9DW09	E9DYI8	Small GTPase-binding protein.	Non-specific serine/threonine protein kinase.	0.516
MAC_01807	MAC_03153	E9DW09	E9DZV5	Small GTPase-binding protein.	Non-specific serine/threonine protein kinase.	0.516
MAC_01807	MAC_04959	E9DW09	E9E511	Small GTPase-binding protein.	Protein RHO1.	0.903
MAC_01807	MAC_05067	E9DW09	E9E598	Small GTPase-binding protein.	Cell division control protein.	0.542
MAC_01807	MAC_08516	E9DW09	E9EF68	Small GTPase-binding protein.	GTPase activating protein (BUD2/CLA2).	0.471
MAC_01831	MAC_05067	E9DW33	E9E598	Putative actin-interacting protein AIP3.	Cell division control protein.	0.656
MAC_02685	MAC_00098	E9DYI8	E9DS25	Non-specific serine/threonine protein kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.568
MAC_02685	MAC_01807	E9DYI8	E9DW09	Non-specific serine/threonine protein kinase.	Small GTPase-binding protein.	0.516
MAC_02685	MAC_03153	E9DYI8	E9DZV5	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.800
MAC_02685	MAC_04959	E9DYI8	E9E511	Non-specific serine/threonine protein kinase.	Protein RHO1.	0.516