(10 nodes) Mitotic DNA damage checkpoint signaling network (Metarhizium acridum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_00683	Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family. (351 aa)
	MAC_01609	BRCT domain-containing protein. (855 aa)
	MAC_01667	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (423 aa)
	MAC_03174	Protein kinase, putative. (1187 aa)
	MAC_03935	Checkpoint protein; Belongs to the HUS1 family. (279 aa)
	MAC_04304	MRC1 domain-containing protein. (1278 aa)
	MAC_07613	Serine/threonine protein kinase, putative. (535 aa)
	MAC_07986	Coiled-coil domain-containing protein 16. (399 aa)
	MAC_09589	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (748 aa)
	MAC_09664	Alpha-1,2-mannosyltransferase (Alg2), putative. (693 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00683	MAC_09589	E9DST5	E9EI91	Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.433
MAC_01609	MAC_01667	E9DVG1	E9DVL9	BRCT domain-containing protein.	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	0.989
MAC_01609	MAC_03174	E9DVG1	E9DZX6	BRCT domain-containing protein.	Protein kinase, putative.	0.549
MAC_01609	MAC_03935	E9DVG1	E9E237	BRCT domain-containing protein.	Checkpoint protein; Belongs to the HUS1 family.	0.867
MAC_01609	MAC_07613	E9DVG1	E9ECL5	BRCT domain-containing protein.	Serine/threonine protein kinase, putative.	0.877
MAC_01609	MAC_09589	E9DVG1	E9EI91	BRCT domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.701
MAC_01667	MAC_01609	E9DVL9	E9DVG1	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	BRCT domain-containing protein.	0.989
MAC_01667	MAC_03174	E9DVL9	E9DZX6	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Protein kinase, putative.	0.718
MAC_01667	MAC_03935	E9DVL9	E9E237	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Checkpoint protein; Belongs to the HUS1 family.	0.999
MAC_01667	MAC_04304	E9DVL9	E9E356	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	MRC1 domain-containing protein.	0.688
MAC_01667	MAC_07613	E9DVL9	E9ECL5	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Serine/threonine protein kinase, putative.	0.837
MAC_01667	MAC_09589	E9DVL9	E9EI91	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.754
MAC_03174	MAC_01609	E9DZX6	E9DVG1	Protein kinase, putative.	BRCT domain-containing protein.	0.549
MAC_03174	MAC_01667	E9DZX6	E9DVL9	Protein kinase, putative.	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	0.718
MAC_03174	MAC_04304	E9DZX6	E9E356	Protein kinase, putative.	MRC1 domain-containing protein.	0.942
MAC_03174	MAC_07613	E9DZX6	E9ECL5	Protein kinase, putative.	Serine/threonine protein kinase, putative.	0.896
MAC_03174	MAC_09589	E9DZX6	E9EI91	Protein kinase, putative.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.427
MAC_03935	MAC_01609	E9E237	E9DVG1	Checkpoint protein; Belongs to the HUS1 family.	BRCT domain-containing protein.	0.867
MAC_03935	MAC_01667	E9E237	E9DVL9	Checkpoint protein; Belongs to the HUS1 family.	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	0.999
MAC_03935	MAC_04304	E9E237	E9E356	Checkpoint protein; Belongs to the HUS1 family.	MRC1 domain-containing protein.	0.413