STRINGSTRING
MAC_00274 MAC_00274 MAC_00314 MAC_00314 MAC_00353 MAC_00353 MAC_00006 MAC_00006 MAC_00557 MAC_00557 MAC_00604 MAC_00604 MAC_00605 MAC_00605 MAC_00673 MAC_00673 MAC_01149 MAC_01149 MAC_01186 MAC_01186 MAC_01304 MAC_01304 cprA cprA MAC_01385 MAC_01385 MAC_01565 MAC_01565 MAC_01689 MAC_01689 MAC_01859 MAC_01859 MAC_01860 MAC_01860 MAC_02508 MAC_02508 MAC_02683 MAC_02683 MAC_02906 MAC_02906 MAC_03394 MAC_03394 MAC_03418 MAC_03418 MAC_03488 MAC_03488 MAC_03659 MAC_03659 MAC_03715 MAC_03715 MAC_03852 MAC_03852 MAC_04040 MAC_04040 MAC_04166 MAC_04166 MAC_04281 MAC_04281 MAC_04305 MAC_04305 MAC_04816 MAC_04816 MAC_04851 MAC_04851 MAC_05162 MAC_05162 MAC_05278 MAC_05278 MAC_05702 MAC_05702 MAC_05797 MAC_05797 MAC_05799 MAC_05799 MAC_06047 MAC_06047 MAC_06298 MAC_06298 MAC_06404 MAC_06404 MAC_06405 MAC_06405 MAC_06608 MAC_06608 MAC_06787 MAC_06787 MAC_06812 MAC_06812 MAC_06970 MAC_06970 MAC_07418 MAC_07418 MAC_07569 MAC_07569 MAC_08015 MAC_08015 MAC_08238 MAC_08238 MAC_08293 MAC_08293 MAC_08424 MAC_08424 MAC_08528 MAC_08528 MAC_08636 MAC_08636 MAC_08655 MAC_08655 MAC_08985 MAC_08985 MAC_09056 MAC_09056 MAC_09221 MAC_09221 MAC_09281 MAC_09281 MAC_09368 MAC_09368 MAC_09644 MAC_09644 MAC_09645 MAC_09645 MAC_09718 MAC_09718 MAC_09731 MAC_09731
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAC_00274Enoyl-CoA hydratase/carnithine racemase. (422 aa)
MAC_00314GTP cyclohydrolase 1. (345 aa)
MAC_00353C-5 sterol desaturase; Belongs to the sterol desaturase family. (348 aa)
MAC_00006Transmembrane domain-containing protein. (170 aa)
MAC_00557Di-trans, poly-cis-decaprenylcistransferase. (253 aa)
MAC_00604Thiamine biosynthetic bifunctional enzyme, putative. (477 aa)
MAC_00605tRNA processing endoribonuclease Trz1, putative. (547 aa)
MAC_00673Phosphomevalonate kinase. (414 aa)
MAC_01149Delta(24(24(1)))-sterol reductase. (573 aa)
MAC_01186Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...] (350 aa)
MAC_01304Squalene epoxidase. (500 aa)
cprANADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (692 aa)
MAC_01385Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1582 aa)
MAC_01565Nmt1 protein. (342 aa)
MAC_01689Serine palmitoyltransferase 1. (516 aa)
MAC_01859Acetylase, putative. (488 aa)
MAC_01860Long-chain-fatty-acid-CoA ligase, putative. (570 aa)
MAC_02508Emopamil binding protein. (223 aa)
MAC_026833-ketosteroid reductase. (478 aa)
MAC_02906Alkyl transferase; Belongs to the UPP synthase family. (358 aa)
MAC_03394Fe-containing alcohol dehydrogenase, putative. (497 aa)
MAC_034183-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (449 aa)
MAC_03488Neutral ceramidase. (742 aa)
MAC_03659Sterol delta 5,6-desaturase ERG3; Belongs to the sterol desaturase family. (345 aa)
MAC_03715Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (494 aa)
MAC_03852Neutral ceramidase. (805 aa)
MAC_04040FAD binding domain protein. (512 aa)
MAC_04166C-3 sterol dehydrogenase/C-4 decarboxylase family protein. (365 aa)
MAC_04281Sterol 24-C-methyltransferase. (202 aa)
MAC_04305Myo-inositol-phosphate synthase. (536 aa)
MAC_04816Sterol desaturase family protein; Belongs to the sterol desaturase family. (241 aa)
MAC_04851Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (319 aa)
MAC_05162C6 transcription factor, putative. (717 aa)
MAC_05278Uncharacterized protein. (274 aa)
MAC_05702Sterol desaturase family. (331 aa)
MAC_05797Uncharacterized protein. (1044 aa)
MAC_05799Kinase; Belongs to the inositol phosphokinase (IPK) family. (1418 aa)
MAC_06047Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (490 aa)
MAC_06298Acetyltransferase. (429 aa)
MAC_06404Pterin-4-alpha-carbinolamine dehydratase family protein. (166 aa)
MAC_06405C-4 sterol methyl oxidase; Belongs to the sterol desaturase family. (261 aa)
MAC_06608Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
MAC_06787Uncharacterized protein. (225 aa)
MAC_06812C-3 sterol dehydrogenase/C-4 decarboxylase. (370 aa)
MAC_06970Delta(24(24(1)))-sterol reductase, putative. (469 aa)
MAC_07418NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (326 aa)
MAC_07569Benzoate 4-monooxygenase cytochrome P450. (492 aa)
MAC_08015Uncharacterized protein. (81 aa)
MAC_08238Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (379 aa)
MAC_08293C-14 sterol reductase, putative. (427 aa)
MAC_08424DAGKc domain-containing protein. (468 aa)
MAC_08528C-14 sterol reductase. (492 aa)
MAC_08636Cytochrome P450 61; Belongs to the cytochrome P450 family. (536 aa)
MAC_086553-oxo-5-alpha-steroid 4-dehydrogenase, putative. (311 aa)
MAC_08985Squalene synthase. (458 aa)
MAC_09056Reverse transcriptase, putative. (767 aa)
MAC_09221Neutral ceramidase. (669 aa)
MAC_09281C-4 methylsterol oxidase; Belongs to the sterol desaturase family. (350 aa)
MAC_09368NADPH-cytochrome P450 reductase. (614 aa)
MAC_09644Sphingosine kinase. (493 aa)
MAC_09645Sphingoid long chain base kinase 4. (195 aa)
MAC_09718Di-trans, poly-cis-decaprenylcistransferase. (153 aa)
MAC_097312-nitropropane dioxygenase. (357 aa)
Your Current Organism:
Metarhizium acridum
NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102
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