(38 nodes) Actin filament binding network (Metarhizium acridum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_02011	Uncharacterized protein. (464 aa)
	MAC_09376	ADF-like domain-containing protein. (146 aa)
	MAC_03861	Putative WD40 domain-containing protein. (610 aa)
	MAC_03688	Calponin. (692 aa)
	MAC_03611	C6 finger domain protein, putative. (463 aa)
	MAC_03557	Actin-like protein 3; Belongs to the actin family. (436 aa)
	MAC_03070	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (359 aa)
	MAC_02913	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (190 aa)
	MAC_02693	DUF500 domain-containing protein. (396 aa)
	MAC_02673	Uncharacterized protein. (637 aa)
	MAC_02658	C6 transcription factor. (504 aa)
	MAC_02416	Tropomyosin-1. (154 aa)
	MAC_02168	C6 transcription factor, putative. (642 aa)
	MAC_01848	Indole-diterpene biosynthesis protein PaxU, putative. (304 aa)
	MAC_00802	Fimbrin. (678 aa)
	MAC_00796	Rossmann-fold NAD(P)(+)-binding protein. (555 aa)
	MAC_00626	Alpha-actinin, sarcomeric (F-actin cross linking protein). (844 aa)
	MAC_00599	Coronin; Belongs to the WD repeat coronin family. (603 aa)
	MAC_00578	FRG1-like family protein. (298 aa)
	MAC_00404	ADP-ribosylation factor. (1521 aa)
	MAC_05353	ANTH domain protein. (1016 aa)
	MAC_05634	C6 transcription factor. (607 aa)
	MAC_05809	Ima1_N domain-containing protein. (814 aa)
	MAC_06338	Twinfilin-1. (723 aa)
	MAC_06686	CRIB domain-containing protein. (834 aa)
	MAC_07094	Uncharacterized protein. (289 aa)
	MAC_07152	Actin binding protein. (777 aa)
	MAC_07264	RRN9 domain-containing protein. (635 aa)
	MAC_07389	Uncharacterized protein. (184 aa)
	MAC_07622	Ras GTPase activating protein. (1676 aa)
	MAC_07690	C6 zinc finger domain protein. (473 aa)
	MAC_07800	Aldolase. (121 aa)
	MAC_07940	Uncharacterized protein. (582 aa)
	MAC_07941	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (169 aa)
	MAC_08822	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (252 aa)
	MAC_09613	SH3 domain protein. (1193 aa)
	MAC_04951	Actin-binding protein Fragmin, putative. (404 aa)
	MAC_04859	Myosin type II heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2388 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00404	MAC_06338	E9DRN5	E9E8Z0	ADP-ribosylation factor.	Twinfilin-1.	0.521
MAC_00599	MAC_00802	E9DSK1	E9DTG4	Coronin; Belongs to the WD repeat coronin family.	Fimbrin.	0.669
MAC_00599	MAC_02416	E9DSK1	E9DXR8	Coronin; Belongs to the WD repeat coronin family.	Tropomyosin-1.	0.462
MAC_00599	MAC_03070	E9DSK1	E9DZM2	Coronin; Belongs to the WD repeat coronin family.	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family.	0.426
MAC_00599	MAC_03557	E9DSK1	E9E109	Coronin; Belongs to the WD repeat coronin family.	Actin-like protein 3; Belongs to the actin family.	0.408
MAC_00599	MAC_03861	E9DSK1	E9E206	Coronin; Belongs to the WD repeat coronin family.	Putative WD40 domain-containing protein.	0.655
MAC_00599	MAC_05353	E9DSK1	E9E655	Coronin; Belongs to the WD repeat coronin family.	ANTH domain protein.	0.605
MAC_00599	MAC_06338	E9DSK1	E9E8Z0	Coronin; Belongs to the WD repeat coronin family.	Twinfilin-1.	0.593
MAC_00599	MAC_07152	E9DSK1	E9EBA4	Coronin; Belongs to the WD repeat coronin family.	Actin binding protein.	0.641
MAC_00626	MAC_00796	E9DSM8	E9DTF8	Alpha-actinin, sarcomeric (F-actin cross linking protein).	Rossmann-fold NAD(P)(+)-binding protein.	0.537
MAC_00626	MAC_02416	E9DSM8	E9DXR8	Alpha-actinin, sarcomeric (F-actin cross linking protein).	Tropomyosin-1.	0.840
MAC_00626	MAC_03688	E9DSM8	E9E1E0	Alpha-actinin, sarcomeric (F-actin cross linking protein).	Calponin.	0.402
MAC_00626	MAC_04859	E9DSM8	E9E4R1	Alpha-actinin, sarcomeric (F-actin cross linking protein).	Myosin type II heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.768
MAC_00626	MAC_07622	E9DSM8	E9ECM4	Alpha-actinin, sarcomeric (F-actin cross linking protein).	Ras GTPase activating protein.	0.402
MAC_00796	MAC_00626	E9DTF8	E9DSM8	Rossmann-fold NAD(P)(+)-binding protein.	Alpha-actinin, sarcomeric (F-actin cross linking protein).	0.537
MAC_00796	MAC_02416	E9DTF8	E9DXR8	Rossmann-fold NAD(P)(+)-binding protein.	Tropomyosin-1.	0.880
MAC_00796	MAC_03557	E9DTF8	E9E109	Rossmann-fold NAD(P)(+)-binding protein.	Actin-like protein 3; Belongs to the actin family.	0.470
MAC_00796	MAC_06686	E9DTF8	E9E9Y8	Rossmann-fold NAD(P)(+)-binding protein.	CRIB domain-containing protein.	0.537
MAC_00796	MAC_07622	E9DTF8	E9ECM4	Rossmann-fold NAD(P)(+)-binding protein.	Ras GTPase activating protein.	0.514
MAC_00802	MAC_00599	E9DTG4	E9DSK1	Fimbrin.	Coronin; Belongs to the WD repeat coronin family.	0.669