(30 nodes) Cellular response to osmotic stress network (Metarhizium acridum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_00216	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (440 aa)
	MAC_00231	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (494 aa)
	MAC_00416	Aldehyde dehydrogenase. (345 aa)
	MAC_00094	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (496 aa)
	MAC_00721	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family. (678 aa)
	MAC_01053	Histidine kinase 1. (1293 aa)
	MAC_01635	MAPKKK cascade protein kinase regulator Ste50. (436 aa)
	MAC_01834	Putative histidine phosphotransferase HPT1p. (150 aa)
	MAC_02020	Putative histidine kinase HHK1p. (2549 aa)
	MAC_02050	Osmosensor protein; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity. (306 aa)
	MAC_02349	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (502 aa)
	MAC_02685	Non-specific serine/threonine protein kinase. (848 aa)
	MAC_03011	Tyrosine-protein phosphatase CDC14. (619 aa)
	MAC_03153	Non-specific serine/threonine protein kinase. (802 aa)
	MAC_03196	MAP kinase kinase kinase. (1348 aa)
	MAC_03732	Hsp90 co-chaperone Cdc37. (482 aa)
	MAC_03817	Putative OPY2 protein. (434 aa)
	MAC_04257	Aldehyde dehydrogenase ALDH; Belongs to the aldehyde dehydrogenase family. (500 aa)
	MAC_04513	Hsp90 co-chaperone Cdc37. (255 aa)
	MAC_04869	Mitogen activated protein kinase kinase. (658 aa)
	MAC_05029	MAP kinase kinase kinase Ste11. (902 aa)
	MAC_05447	Uncharacterized protein. (190 aa)
	MAC_05900	Putative histidine kinase HHK5p. (1121 aa)
	MAC_06092	DUF1690 domain-containing protein. (196 aa)
	MAC_06621	Dehydrogenase; Belongs to the aldehyde dehydrogenase family. (321 aa)
	MAC_06767	Uncharacterized protein. (378 aa)
	MAC_06861	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (508 aa)
	MAC_07801	Putative cell surface flocculin. (840 aa)
	MAC_08091	Homoserine dehydrogenase. (363 aa)
	MAC_08199	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (494 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_01053	MAC_01834	E9DTV5	E9DW36	Histidine kinase 1.	Putative histidine phosphotransferase HPT1p.	0.689
MAC_01053	MAC_03196	E9DTV5	E9DZZ8	Histidine kinase 1.	MAP kinase kinase kinase.	0.561
MAC_01635	MAC_01834	E9DVI7	E9DW36	MAPKKK cascade protein kinase regulator Ste50.	Putative histidine phosphotransferase HPT1p.	0.487
MAC_01635	MAC_02050	E9DVI7	E9DWQ2	MAPKKK cascade protein kinase regulator Ste50.	Osmosensor protein; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	0.969
MAC_01635	MAC_03196	E9DVI7	E9DZZ8	MAPKKK cascade protein kinase regulator Ste50.	MAP kinase kinase kinase.	0.449
MAC_01635	MAC_03817	E9DVI7	E9E1W2	MAPKKK cascade protein kinase regulator Ste50.	Putative OPY2 protein.	0.971
MAC_01635	MAC_04869	E9DVI7	E9E4S1	MAPKKK cascade protein kinase regulator Ste50.	Mitogen activated protein kinase kinase.	0.622
MAC_01635	MAC_05029	E9DVI7	E9E560	MAPKKK cascade protein kinase regulator Ste50.	MAP kinase kinase kinase Ste11.	0.994
MAC_01635	MAC_05900	E9DVI7	E9E7Q2	MAPKKK cascade protein kinase regulator Ste50.	Putative histidine kinase HHK5p.	0.540
MAC_01834	MAC_01053	E9DW36	E9DTV5	Putative histidine phosphotransferase HPT1p.	Histidine kinase 1.	0.689
MAC_01834	MAC_01635	E9DW36	E9DVI7	Putative histidine phosphotransferase HPT1p.	MAPKKK cascade protein kinase regulator Ste50.	0.487
MAC_01834	MAC_02020	E9DW36	E9DWM2	Putative histidine phosphotransferase HPT1p.	Putative histidine kinase HHK1p.	0.582
MAC_01834	MAC_02050	E9DW36	E9DWQ2	Putative histidine phosphotransferase HPT1p.	Osmosensor protein; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	0.599
MAC_01834	MAC_03196	E9DW36	E9DZZ8	Putative histidine phosphotransferase HPT1p.	MAP kinase kinase kinase.	0.668
MAC_01834	MAC_04869	E9DW36	E9E4S1	Putative histidine phosphotransferase HPT1p.	Mitogen activated protein kinase kinase.	0.749
MAC_01834	MAC_05029	E9DW36	E9E560	Putative histidine phosphotransferase HPT1p.	MAP kinase kinase kinase Ste11.	0.499
MAC_01834	MAC_05900	E9DW36	E9E7Q2	Putative histidine phosphotransferase HPT1p.	Putative histidine kinase HHK5p.	0.997
MAC_02020	MAC_01834	E9DWM2	E9DW36	Putative histidine kinase HHK1p.	Putative histidine phosphotransferase HPT1p.	0.582
MAC_02020	MAC_03196	E9DWM2	E9DZZ8	Putative histidine kinase HHK1p.	MAP kinase kinase kinase.	0.414
MAC_02050	MAC_01635	E9DWQ2	E9DVI7	Osmosensor protein; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	MAPKKK cascade protein kinase regulator Ste50.	0.969