(40 nodes) Vesicle tethering complex network (Metarhizium acridum)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	MAC_00118	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events. (657 aa)
	MAC_00558	Exocyst complex component Sec10. (871 aa)
	MAC_00993	Vacuolar protein sorting 33A-like protein; Belongs to the STXBP/unc-18/SEC1 family. (1739 aa)
	MAC_01855	AvaB protein. (1059 aa)
	MAC_02059	Uncharacterized protein. (226 aa)
	MAC_02080	Putative exocyst complex component sec8. (1068 aa)
	MAC_02270	Uncharacterized protein. (393 aa)
	MAC_02432	Secretion pathway protein Sls2/Rcy1. (925 aa)
	MAC_02476	TRAPP complex component Bet3. (138 aa)
	MAC_02514	Trafficking protein particle complex subunit 2, putative. (156 aa)
	MAC_02777	Putative PEP5 protein. (1209 aa)
	MAC_03138	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (185 aa)
	MAC_03393	Sec3-PIP2_bind domain-containing protein. (1398 aa)
	MAC_03869	Uncharacterized protein. (184 aa)
	MAC_04131	Vacuolar protein sorting-associated protein. (741 aa)
	MAC_04634	Sec34-like family protein. (785 aa)
	MAC_04637	RINT-1 family protein. (797 aa)
	MAC_04645	Uncharacterized protein. (279 aa)
	MAC_05004	Uncharacterized protein. (784 aa)
	MAC_05047	Vacuolar protein sorting protein DigA. (966 aa)
	MAC_05287	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (194 aa)
	MAC_05613	Uncharacterized protein. (752 aa)
	MAC_05979	GARP complex component (Vps54), putative. (1050 aa)
	MAC_06045	Trafficking protein particle complex subunit; Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic. (213 aa)
	MAC_06179	Uncharacterized protein. (599 aa)
	MAC_06233	Golgi complex component. (1550 aa)
	MAC_06195	GARP complex subunit Vps53. (797 aa)
	MAC_06411	Exocyst complex component EXO84. (676 aa)
	MAC_06447	Protein transport protein Sec39. (758 aa)
	MAC_06465	Exocyst complex component SEC15; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (723 aa)
	MAC_06517	DUF974 domain-containing protein. (353 aa)
	MAC_07778	Exocyst complex component SEC5; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (1059 aa)
	MAC_08186	Uncharacterized protein. (712 aa)
	MAC_08631	Vps52 / Sac2 family protein. (674 aa)
	MAC_09011	GARP complex component (Vps54), putative. (1018 aa)
	MAC_09077	Uncharacterized protein. (423 aa)
	MAC_09117	Exocyst complex protein EXO70; Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst. Belongs to the EXO70 family. (628 aa)
	MAC_09213	Golgi transport complex component Cog5. (442 aa)
	MAC_09484	Vacuolar assembly protein, putative. (1313 aa)
	MAC_09691	TMEM1 family protein. (1542 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00118	MAC_00993	E9DS45	E9DTP5	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.	Vacuolar protein sorting 33A-like protein; Belongs to the STXBP/unc-18/SEC1 family.	0.535
MAC_00118	MAC_02080	E9DS45	E9DWT2	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.	Putative exocyst complex component sec8.	0.601
MAC_00118	MAC_02777	E9DS45	E9DYS9	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.	Putative PEP5 protein.	0.420
MAC_00118	MAC_03138	E9DS45	E9DZU0	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.	0.540
MAC_00118	MAC_03393	E9DS45	E9E0J5	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.	Sec3-PIP2_bind domain-containing protein.	0.463
MAC_00118	MAC_04634	E9DS45	E9E436	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.	Sec34-like family protein.	0.998
MAC_00118	MAC_04637	E9DS45	E9E439	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.	RINT-1 family protein.	0.552
MAC_00118	MAC_04645	E9DS45	E9E447	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.	Uncharacterized protein.	0.775
MAC_00118	MAC_05004	E9DS45	E9E535	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.	Uncharacterized protein.	0.998
MAC_00118	MAC_05613	E9DS45	E9E6W5	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.	Uncharacterized protein.	0.641
MAC_00118	MAC_05979	E9DS45	E9E7Y1	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.	GARP complex component (Vps54), putative.	0.774
MAC_00118	MAC_06195	E9DS45	E9E8N7	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.	GARP complex subunit Vps53.	0.865
MAC_00118	MAC_06411	E9DS45	E9E963	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.	Exocyst complex component EXO84.	0.635
MAC_00118	MAC_06465	E9DS45	E9E9B7	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.	Exocyst complex component SEC15; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	0.504
MAC_00118	MAC_07778	E9DS45	E9ED30	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.	Exocyst complex component SEC5; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	0.578
MAC_00118	MAC_08631	E9DS45	E9EFI3	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.	Vps52 / Sac2 family protein.	0.857
MAC_00118	MAC_09011	E9DS45	E9EGL3	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.	GARP complex component (Vps54), putative.	0.774
MAC_00118	MAC_09077	E9DS45	E9EGS9	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.	Uncharacterized protein.	0.999
MAC_00118	MAC_09117	E9DS45	E9EGW9	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.	Exocyst complex protein EXO70; Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst. Belongs to the EXO70 family.	0.660
MAC_00118	MAC_09213	E9DS45	E9EH65	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.	Golgi transport complex component Cog5.	0.900