STRINGSTRING
MAC_07474 MAC_07474 MAC_00141 MAC_00141 MAC_00224 MAC_00224 MAC_00274 MAC_00274 MAC_00314 MAC_00314 MAC_00337 MAC_00337 MAC_00353 MAC_00353 MAC_00006 MAC_00006 MAC_00557 MAC_00557 MAC_00604 MAC_00604 MAC_00605 MAC_00605 MAC_00673 MAC_00673 MAC_01116 MAC_01116 MAC_01149 MAC_01149 MAC_01186 MAC_01186 MAC_01304 MAC_01304 MAC_01322 MAC_01322 MAC_01332 MAC_01332 cprA cprA MAC_01385 MAC_01385 MAC_01523 MAC_01523 MAC_01452 MAC_01452 MAC_01565 MAC_01565 MAC_01689 MAC_01689 MAC_01750 MAC_01750 MAC_01859 MAC_01859 MAC_01860 MAC_01860 MAC_02447 MAC_02447 MAC_02508 MAC_02508 MAC_02683 MAC_02683 MAC_02717 MAC_02717 MAC_02757 MAC_02757 MAC_02791 MAC_02791 MAC_02875 MAC_02875 MAC_02882 MAC_02882 MAC_02906 MAC_02906 MAC_02956 MAC_02956 MAC_03394 MAC_03394 MAC_03418 MAC_03418 MAC_03488 MAC_03488 MAC_03508 MAC_03508 MAC_03516 MAC_03516 MAC_03525 MAC_03525 MAC_03659 MAC_03659 MAC_03665 MAC_03665 MAC_03672 MAC_03672 MAC_03715 MAC_03715 MAC_03906 MAC_03906 MAC_03852 MAC_03852 MAC_04034 MAC_04034 MAC_04040 MAC_04040 MAC_04166 MAC_04166 MAC_04281 MAC_04281 MAC_04305 MAC_04305 MAC_04481 MAC_04481 MAC_04533 MAC_04533 qutE qutE MAC_04816 MAC_04816 MAC_04851 MAC_04851 MAC_05019 MAC_05019 MAC_05119 MAC_05119 MAC_05162 MAC_05162 MAC_05192 MAC_05192 MAC_05278 MAC_05278 MAC_05702 MAC_05702 MAC_05797 MAC_05797 MAC_05799 MAC_05799 MAC_05892 MAC_05892 MAC_06047 MAC_06047 MAC_06048 MAC_06048 MAC_06105 MAC_06105 MAC_06138 MAC_06138 MAC_06252 MAC_06252 MAC_06270 MAC_06270 MAC_06298 MAC_06298 MAC_06382 MAC_06382 MAC_06404 MAC_06404 MAC_06405 MAC_06405 MAC_06608 MAC_06608 MAC_06731 MAC_06731 MAC_06787 MAC_06787 MAC_06812 MAC_06812 MAC_06944 MAC_06944 MAC_06970 MAC_06970 MAC_07103 MAC_07103 MAC_07142 MAC_07142 MAC_07199 MAC_07199 MAC_07322 MAC_07322 MAC_07323 MAC_07323 MAC_07418 MAC_07418 MAC_07469 MAC_07469 MAC_07473 MAC_07473 MAC_07569 MAC_07569 MAC_07629 MAC_07629 MAC_07637 MAC_07637 MAC_07638 MAC_07638 MAC_07681 MAC_07681 MAC_07907 MAC_07907 MAC_07958 MAC_07958 MAC_08015 MAC_08015 MAC_08229 MAC_08229 MAC_08238 MAC_08238 MAC_08293 MAC_08293 MAC_08424 MAC_08424 MAC_08454 MAC_08454 MAC_08528 MAC_08528 MAC_08636 MAC_08636 MAC_08655 MAC_08655 MAC_08731 MAC_08731 MAC_08985 MAC_08985 MAC_09041 MAC_09041 MAC_09043 MAC_09043 MAC_09056 MAC_09056 MAC_09167 MAC_09167 MAC_09221 MAC_09221 MAC_09281 MAC_09281 Arp2 Arp2 MAC_09368 MAC_09368 MAC_09394 MAC_09394 MAC_09514 MAC_09514 MAC_09644 MAC_09644 MAC_09645 MAC_09645 MAC_09676 MAC_09676 MAC_09696 MAC_09696 MAC_09718 MAC_09718 MAC_09731 MAC_09731 MAC_09790 MAC_09790
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAC_07474Pyridoxine biosynthesis protein PDX1; Belongs to the PdxS/SNZ family. (310 aa)
MAC_00141Uncharacterized protein. (1272 aa)
MAC_00224GAL4 & Fungal specific transcription factor domain containing protein. (575 aa)
MAC_00274Enoyl-CoA hydratase/carnithine racemase. (422 aa)
MAC_00314GTP cyclohydrolase 1. (345 aa)
MAC_00337Cytochrome b5, putative; Belongs to the cytochrome b5 family. (84 aa)
MAC_00353C-5 sterol desaturase; Belongs to the sterol desaturase family. (348 aa)
MAC_00006Transmembrane domain-containing protein. (170 aa)
MAC_00557Di-trans, poly-cis-decaprenylcistransferase. (253 aa)
MAC_00604Thiamine biosynthetic bifunctional enzyme, putative. (477 aa)
MAC_00605tRNA processing endoribonuclease Trz1, putative. (547 aa)
MAC_00673Phosphomevalonate kinase. (414 aa)
MAC_01116Cytochrome P450 4F8; Belongs to the cytochrome P450 family. (477 aa)
MAC_01149Delta(24(24(1)))-sterol reductase. (573 aa)
MAC_01186Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...] (350 aa)
MAC_01304Squalene epoxidase. (500 aa)
MAC_01322GNAT family acetyltransferase, putative. (228 aa)
MAC_01332Amidohydro-rel domain-containing protein; Belongs to the metallo-dependent hydrolases superfamily. (273 aa)
cprANADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (692 aa)
MAC_01385Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1582 aa)
MAC_01523Monooxygenase, putative. (431 aa)
MAC_01452Pfs, NACHT and Ankyrin domain protein; Belongs to the cytochrome P450 family. (596 aa)
MAC_01565Nmt1 protein. (342 aa)
MAC_01689Serine palmitoyltransferase 1. (516 aa)
MAC_01750Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (391 aa)
MAC_01859Acetylase, putative. (488 aa)
MAC_01860Long-chain-fatty-acid-CoA ligase, putative. (570 aa)
MAC_02447Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (350 aa)
MAC_02508Emopamil binding protein. (223 aa)
MAC_026833-ketosteroid reductase. (478 aa)
MAC_02717Tyrosinase 2. (533 aa)
MAC_02757Siderophore biosynthesis enzyme, putative. (196 aa)
MAC_027913-hydroxy-3-methylglutaryl coenzyme A reductase. (1254 aa)
MAC_02875Cytochrome P450, putative. (451 aa)
MAC_02882Glycosyltransferase. (1006 aa)
MAC_02906Alkyl transferase; Belongs to the UPP synthase family. (358 aa)
MAC_02956Tyrosinase. (602 aa)
MAC_03394Fe-containing alcohol dehydrogenase, putative. (497 aa)
MAC_034183-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (449 aa)
MAC_03488Neutral ceramidase. (742 aa)
MAC_03508Putative cytochrome b5; Belongs to the cytochrome b5 family. (142 aa)
MAC_03516Toxin biosynthesis protein, putative. (419 aa)
MAC_03525AP-1-like protein. (575 aa)
MAC_03659Sterol delta 5,6-desaturase ERG3; Belongs to the sterol desaturase family. (345 aa)
MAC_03665Tyrosinase domain protein. (610 aa)
MAC_03672Uracil-5-carboxylate decarboxylase; Belongs to the metallo-dependent hydrolases superfamily. (342 aa)
MAC_03715Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (494 aa)
MAC_03906Putative 5-oxoprolinase. (1364 aa)
MAC_03852Neutral ceramidase. (805 aa)
MAC_04034Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (229 aa)
MAC_04040FAD binding domain protein. (512 aa)
MAC_04166C-3 sterol dehydrogenase/C-4 decarboxylase family protein. (365 aa)
MAC_04281Sterol 24-C-methyltransferase. (202 aa)
MAC_04305Myo-inositol-phosphate synthase. (536 aa)
MAC_04481N-acetyltransferase domain-containing protein. (229 aa)
MAC_04533Quinate dehydrogenase. (241 aa)
qutECatabolic 3-dehydroquinase; Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway; Belongs to the type-II 3-dehydroquinase family. (149 aa)
MAC_04816Sterol desaturase family protein; Belongs to the sterol desaturase family. (241 aa)
MAC_04851Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (319 aa)
MAC_05019INSIG domain-containing protein. (413 aa)
MAC_05119Alpha-methylacyl-CoA racemase. (400 aa)
MAC_05162C6 transcription factor, putative. (717 aa)
MAC_05192UDP-glucose,sterol transferase. (1079 aa)
MAC_05278Uncharacterized protein. (274 aa)
MAC_05702Sterol desaturase family. (331 aa)
MAC_05797Uncharacterized protein. (1044 aa)
MAC_05799Kinase; Belongs to the inositol phosphokinase (IPK) family. (1418 aa)
MAC_05892ThiJ/PfpI family protein. (316 aa)
MAC_06047Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (490 aa)
MAC_06048UDP-glucose,sterol transferase. (1021 aa)
MAC_06105Vegetative incompatibility protein HET-E-1. (186 aa)
MAC_06138ThiJ/PfpI family protein. (185 aa)
MAC_06252Toxin biosynthesis protein, putative. (414 aa)
MAC_06270Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (354 aa)
MAC_06298Acetyltransferase. (429 aa)
MAC_06382Pyridoxamine 5'-phosphate oxidase. (249 aa)
MAC_06404Pterin-4-alpha-carbinolamine dehydratase family protein. (166 aa)
MAC_06405C-4 sterol methyl oxidase; Belongs to the sterol desaturase family. (261 aa)
MAC_06608Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
MAC_06731ThiJ/PfpI family protein. (291 aa)
MAC_06787Uncharacterized protein. (225 aa)
MAC_06812C-3 sterol dehydrogenase/C-4 decarboxylase. (370 aa)
MAC_06944P450 monooxygenase; Belongs to the cytochrome P450 family. (494 aa)
MAC_06970Delta(24(24(1)))-sterol reductase, putative. (469 aa)
MAC_07103Cytochrome P450 51B; Belongs to the cytochrome P450 family. (527 aa)
MAC_07142Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (354 aa)
MAC_07199Uncharacterized protein. (403 aa)
MAC_07322ThiJ/PfpI family protein. (216 aa)
MAC_07323ThiJ/PfpI family protein. (228 aa)
MAC_07418NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (326 aa)
MAC_074695-oxoprolinase. (1217 aa)
MAC_07473Pyridoxine. (228 aa)
MAC_07569Benzoate 4-monooxygenase cytochrome P450. (492 aa)
MAC_07629Glucosyl/glucuronosyl transferase, putative. (1401 aa)
MAC_07637N-acetyltransferase domain-containing protein. (227 aa)
MAC_07638Uncharacterized protein. (142 aa)
MAC_07681Pfs, NACHT and Ankyrin domain protein. (463 aa)
MAC_07907Zn(2)-C6 fungal-type domain-containing protein. (732 aa)
MAC_07958Tyrosinase, putative. (530 aa)
MAC_08015Uncharacterized protein. (81 aa)
MAC_08229Uncharacterized protein. (182 aa)
MAC_08238Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (379 aa)
MAC_08293C-14 sterol reductase, putative. (427 aa)
MAC_08424DAGKc domain-containing protein. (468 aa)
MAC_08454Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (363 aa)
MAC_08528C-14 sterol reductase. (492 aa)
MAC_08636Cytochrome P450 61; Belongs to the cytochrome P450 family. (536 aa)
MAC_086553-oxo-5-alpha-steroid 4-dehydrogenase, putative. (311 aa)
MAC_08731Cytochrome P450 51A; Belongs to the cytochrome P450 family. (142 aa)
MAC_08985Squalene synthase. (458 aa)
MAC_09041UDP-glucose,sterol transferase. (1045 aa)
MAC_09043Beta transducin-like protein HET-D2Y. (738 aa)
MAC_09056Reverse transcriptase, putative. (767 aa)
MAC_09167Nitroreductase family protein. (212 aa)
MAC_09221Neutral ceramidase. (669 aa)
MAC_09281C-4 methylsterol oxidase; Belongs to the sterol desaturase family. (350 aa)
Arp2Hydroxynaphthalene reductase-like protein Arp2; Hydroxynaphthalene reductase-like protein; part of the Pks2 gene cluster that mediates the formation of infectious structures (appressoria), enabling these fungi to kill insects faster. The product of the Pks2 gene cluster is different from the one of Pks1 and has still not been identified. (267 aa)
MAC_09368NADPH-cytochrome P450 reductase. (614 aa)
MAC_09394C-8 sterol isomerase (Erg-1), putative. (220 aa)
MAC_09514Glyco_transf_28 domain-containing protein. (815 aa)
MAC_09644Sphingosine kinase. (493 aa)
MAC_09645Sphingoid long chain base kinase 4. (195 aa)
MAC_09676ThiJ/PfpI family protein. (217 aa)
MAC_09696DUF2236 domain-containing protein. (403 aa)
MAC_09718Di-trans, poly-cis-decaprenylcistransferase. (153 aa)
MAC_097312-nitropropane dioxygenase. (357 aa)
MAC_09790F-box domain-containing protein. (347 aa)
Your Current Organism:
Metarhizium acridum
NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102
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