(17 nodes) Organelle disassembly network (Metarhizium acridum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_01582	Protein DOM34 homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (411 aa)
	MAC_06181	RNase L inhibitor of the ABC superfamily. (680 aa)
	MAC_00117	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (404 aa)
	MAC_00679	Elongation factor Tu GTP binding domain containing protein. (825 aa)
	MAC_07257	Kinesin related protein 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1156 aa)
	MAC_06708	Proteasome-activating nucleotidase. (528 aa)
	MAC_06303	Autophagy-related protein 17. (503 aa)
	MAC_06211	Ribosomal recycling factor, putative. (290 aa)
	MAC_04366	SVP1-like protein 2. (349 aa)
	MAC_04323	ATP-dependent Zn protease. (489 aa)
	MAC_04153	NPL4 family protein. (650 aa)
	MAC_03987	ESCRT-III component. (110 aa)
	MAC_03218	Autophagy-related protein 11. (1347 aa)
	MAC_03126	Uncharacterized protein. (162 aa)
	MAC_03011	Tyrosine-protein phosphatase CDC14. (619 aa)
	MAC_02614	ESCRT-III component. (223 aa)
	MAC_02555	Cell division control protein Cdc48; Belongs to the AAA ATPase family. (818 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00117	MAC_03218	E9DS44	E9E020	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	Autophagy-related protein 11.	0.983
MAC_00117	MAC_04366	E9DS44	E9E3B8	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	SVP1-like protein 2.	0.654
MAC_00117	MAC_06303	E9DS44	E9E8V5	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	Autophagy-related protein 17.	0.983
MAC_00679	MAC_06211	E9DST1	E9E8J6	Elongation factor Tu GTP binding domain containing protein.	Ribosomal recycling factor, putative.	0.864
MAC_01582	MAC_06181	E9DVD4	E9E8I3	Protein DOM34 homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs.	RNase L inhibitor of the ABC superfamily.	0.908
MAC_01582	MAC_06211	E9DVD4	E9E8J6	Protein DOM34 homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs.	Ribosomal recycling factor, putative.	0.632
MAC_02555	MAC_04153	E9DY57	E9E2Q5	Cell division control protein Cdc48; Belongs to the AAA ATPase family.	NPL4 family protein.	0.994
MAC_02555	MAC_04323	E9DY57	E9E375	Cell division control protein Cdc48; Belongs to the AAA ATPase family.	ATP-dependent Zn protease.	0.900
MAC_02555	MAC_06708	E9DY57	E9EA10	Cell division control protein Cdc48; Belongs to the AAA ATPase family.	Proteasome-activating nucleotidase.	0.900
MAC_02614	MAC_03987	E9DYB6	E9E289	ESCRT-III component.	ESCRT-III component.	0.900
MAC_03011	MAC_07257	E9DZG3	E9EBK9	Tyrosine-protein phosphatase CDC14.	Kinesin related protein 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.498
MAC_03218	MAC_00117	E9E020	E9DS44	Autophagy-related protein 11.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.983
MAC_03218	MAC_06303	E9E020	E9E8V5	Autophagy-related protein 11.	Autophagy-related protein 17.	0.879
MAC_03987	MAC_02614	E9E289	E9DYB6	ESCRT-III component.	ESCRT-III component.	0.900
MAC_04153	MAC_02555	E9E2Q5	E9DY57	NPL4 family protein.	Cell division control protein Cdc48; Belongs to the AAA ATPase family.	0.994
MAC_04153	MAC_04323	E9E2Q5	E9E375	NPL4 family protein.	ATP-dependent Zn protease.	0.994
MAC_04153	MAC_06708	E9E2Q5	E9EA10	NPL4 family protein.	Proteasome-activating nucleotidase.	0.990
MAC_04323	MAC_02555	E9E375	E9DY57	ATP-dependent Zn protease.	Cell division control protein Cdc48; Belongs to the AAA ATPase family.	0.900
MAC_04323	MAC_04153	E9E375	E9E2Q5	ATP-dependent Zn protease.	NPL4 family protein.	0.994
MAC_04323	MAC_06708	E9E375	E9EA10	ATP-dependent Zn protease.	Proteasome-activating nucleotidase.	0.906