(33 nodes) Integral component of endoplasmic reticulum membrane network (Metarhizium acridum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_04091	Lectin family integral membrane protein, putative. (431 aa)
	MAC_03729	DUF1682 domain protein. (432 aa)
	MAC_03698	DUF1183 domain protein. (310 aa)
	MAC_03607	Phosphatidate cytidylyltransferase family protein. (626 aa)
	MAC_03350	Cytomegalovirus gH-receptor family protein, putative. (991 aa)
	MAC_03345	GPI transamidase component GPI16. (585 aa)
	MAC_03246	Membrane-tethered transcription factor (SPT23), putative. (471 aa)
	MAC_02873	TRAM1-like protein & fumonisin. (465 aa)
	MAC_00042	Ankyrin repeat protein. (1389 aa)
	MAC_00517	Dolichyl pyrophosphate phosphatase. (237 aa)
	MAC_00664	ER membrane protein complex subunit 4; Belongs to the EMC4 family. (167 aa)
	MAC_01267	RTA1 domain protein, putative. (250 aa)
	MAC_01690	Rhomboid protein 2. (603 aa)
	MAC_01887	CaaX prenyl proteinase Rce1. (326 aa)
	MAC_02874	TLC domain-containing protein. (374 aa)
	MAC_02552	Longevity-assurance family protein. (461 aa)
	MAC_06467	SUN domain-containing protein. (902 aa)
	MAC_06681	Sulfatase, putative. (843 aa)
	MAC_07266	Putative cell division control protein CDC91. (421 aa)
	MAC_07484	Uncharacterized protein. (212 aa)
	MAC_07803	Sulfhydryl oxidase. (236 aa)
	MAC_08355	Intramembrane protease. (571 aa)
	MAC_08483	Longevity-assurance protein (LAC1), putative. (472 aa)
	MAC_09048	GPI transamidase component PIG-S, putative. (566 aa)
	MAC_09323	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family. (234 aa)
	MAC_09439	DUF2012 domain-containing protein. (236 aa)
	MAC_02426	Tetratricopeptide repeat domain-containing protein. (340 aa)
	MAC_06374	Uncharacterized protein. (720 aa)
	MAC_06373	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (389 aa)
	MAC_06032	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (456 aa)
	MAC_05658	Uncharacterized protein. (126 aa)
	MAC_04943	Integral ER membrane protein Scs2. (320 aa)
	MAC_04422	EMC1_C domain-containing protein. (968 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00664	MAC_02426	E9DSR6	E9DXS8	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	Tetratricopeptide repeat domain-containing protein.	0.995
MAC_00664	MAC_04422	E9DSR6	E9E3H4	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	EMC1_C domain-containing protein.	0.995
MAC_00664	MAC_09323	E9DSR6	E9EHH5	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family.	0.996
MAC_00664	MAC_09439	E9DSR6	E9EHU1	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	DUF2012 domain-containing protein.	0.964
MAC_01690	MAC_03345	E9DVP2	E9E0E7	Rhomboid protein 2.	GPI transamidase component GPI16.	0.999
MAC_01690	MAC_06373	E9DVP2	E9E925	Rhomboid protein 2.	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	0.995
MAC_01690	MAC_06374	E9DVP2	E9E926	Rhomboid protein 2.	Uncharacterized protein.	0.952
MAC_01690	MAC_07266	E9DVP2	E9EBL8	Rhomboid protein 2.	Putative cell division control protein CDC91.	0.998
MAC_01690	MAC_09048	E9DVP2	E9EGQ0	Rhomboid protein 2.	GPI transamidase component PIG-S, putative.	0.999
MAC_01887	MAC_06032	E9DW89	E9E834	CaaX prenyl proteinase Rce1.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.978
MAC_02426	MAC_00664	E9DXS8	E9DSR6	Tetratricopeptide repeat domain-containing protein.	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	0.995
MAC_02426	MAC_03729	E9DXS8	E9E1I1	Tetratricopeptide repeat domain-containing protein.	DUF1682 domain protein.	0.400
MAC_02426	MAC_04422	E9DXS8	E9E3H4	Tetratricopeptide repeat domain-containing protein.	EMC1_C domain-containing protein.	0.996
MAC_02426	MAC_09323	E9DXS8	E9EHH5	Tetratricopeptide repeat domain-containing protein.	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family.	0.996
MAC_02426	MAC_09439	E9DXS8	E9EHU1	Tetratricopeptide repeat domain-containing protein.	DUF2012 domain-containing protein.	0.946
MAC_02552	MAC_02873	E9DY54	E9DZ25	Longevity-assurance family protein.	TRAM1-like protein & fumonisin.	0.900
MAC_02552	MAC_02874	E9DY54	E9DZ26	Longevity-assurance family protein.	TLC domain-containing protein.	0.903
MAC_02552	MAC_08483	E9DY54	E9EF35	Longevity-assurance family protein.	Longevity-assurance protein (LAC1), putative.	0.900
MAC_02873	MAC_02552	E9DZ25	E9DY54	TRAM1-like protein & fumonisin.	Longevity-assurance family protein.	0.900
MAC_02873	MAC_02874	E9DZ25	E9DZ26	TRAM1-like protein & fumonisin.	TLC domain-containing protein.	0.900