(39 nodes) Toll Like Receptor 3 (TLR3) Cascade network (Metarhizium acridum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_08344	Protein phosphatase PP2A regulatory subunit A. (625 aa)
	MAC_08525	Uncharacterized protein. (385 aa)
	MAC_08741	Transcription factor ATF2. (325 aa)
	MAC_08893	Uncharacterized protein. (141 aa)
	MAC_08931	Transcription factor atf21. (256 aa)
	MAC_09388	Phosphotransferase enzyme family protein. (260 aa)
	MAC_09841	Complex I intermediate-associated protein 30. (227 aa)
	MAC_02314	MAP kinase kinase EMK1. (506 aa)
	MAC_02436	Putative stretch-activated Ca channel. (809 aa)
	MAC_02758	Cross-pathway control 1. (572 aa)
	MAC_02642	Ubiquitin. (343 aa)
	MAC_02766	Tyrosine phosphatase. (194 aa)
	MAC_02793	Uncharacterized protein. (186 aa)
	MAC_03311	NLRC4_HD2 domain-containing protein. (1285 aa)
	MAC_03678	Protein-tyrosine phosphatase, putative. (815 aa)
	MAC_03879	TYR_PHOSPHATASE_2 domain-containing protein. (286 aa)
	MAC_03844	Putative bZip transcription factor. (492 aa)
	MAC_04852	Ser/Thr protein phosphatase family. (357 aa)
	MAC_04869	Mitogen activated protein kinase kinase. (658 aa)
	MAC_04957	APH domain-containing protein. (396 aa)
	MAC_02794	Phosphotransferase family protein. (347 aa)
	MAC_02926	Uncharacterized protein. (229 aa)
	MAC_00358	APH domain-containing protein. (320 aa)
	MAC_00098	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
	MAC_01700	Dual specificity phosphatase, putative. (454 aa)
	MAC_01782	Ser/Thr protein phosphatase family protein. (319 aa)
	MAC_01946	Ubiquitin. (153 aa)
	MAC_02192	Uncharacterized protein. (207 aa)
	MAC_05430	Protein kinase domain-containing protein. (259 aa)
	MAC_05725	APH domain-containing protein. (287 aa)
	MAC_05764	TRAF-type zinc finger protein. (555 aa)
	MAC_06412	Serine/threonine-protein phosphatase. (309 aa)
	MAC_06603	APH domain-containing protein. (311 aa)
	MAC_07002	Uncharacterized protein. (470 aa)
	MAC_07242	Caleosin domain containing protein. (194 aa)
	MAC_07922	Uncharacterized protein. (139 aa)
	MAC_08024	Mitogen-activated protein kinase. (429 aa)
	MAC_08084	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa)
	MAC_08284	BZIP domain-containing protein. (257 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00098	MAC_01700	E9DS25	E9DVQ2	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Dual specificity phosphatase, putative.	0.532
MAC_00098	MAC_02314	E9DS25	E9DXG6	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	MAP kinase kinase EMK1.	0.998
MAC_00098	MAC_02436	E9DS25	E9DXT8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Putative stretch-activated Ca channel.	0.521
MAC_00098	MAC_02758	E9DS25	E9DYC7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Cross-pathway control 1.	0.516
MAC_00098	MAC_02926	E9DS25	E9DZ78	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.588
MAC_00098	MAC_03678	E9DS25	E9E1D0	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein-tyrosine phosphatase, putative.	0.986
MAC_00098	MAC_03844	E9DS25	E9E1Y9	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Putative bZip transcription factor.	0.604
MAC_00098	MAC_04869	E9DS25	E9E4S1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen activated protein kinase kinase.	0.855
MAC_00098	MAC_06412	E9DS25	E9E964	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Serine/threonine-protein phosphatase.	0.497
MAC_00098	MAC_07242	E9DS25	E9EBJ4	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Caleosin domain containing protein.	0.532
MAC_00098	MAC_08024	E9DS25	E9EDS6	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.465
MAC_00098	MAC_08084	E9DS25	E9EDY6	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.707
MAC_00098	MAC_08344	E9DS25	E9EEP6	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein phosphatase PP2A regulatory subunit A.	0.422
MAC_00098	MAC_08525	E9DS25	E9EF77	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.604
MAC_00098	MAC_08741	E9DS25	E9EFU3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Transcription factor ATF2.	0.584
MAC_00098	MAC_08931	E9DS25	E9EGD3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Transcription factor atf21.	0.584
MAC_00358	MAC_02758	E9DRI9	E9DYC7	APH domain-containing protein.	Cross-pathway control 1.	0.638
MAC_01700	MAC_00098	E9DVQ2	E9DS25	Dual specificity phosphatase, putative.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.532
MAC_01700	MAC_02436	E9DVQ2	E9DXT8	Dual specificity phosphatase, putative.	Putative stretch-activated Ca channel.	0.532
MAC_01700	MAC_08024	E9DVQ2	E9EDS6	Dual specificity phosphatase, putative.	Mitogen-activated protein kinase.	0.532