STRINGSTRING
MAC_02898 MAC_02898 MAC_03029 MAC_03029 MAC_03039 MAC_03039 MAC_03101 MAC_03101 MAC_03188 MAC_03188 MAC_03210 MAC_03210 MAC_03262 MAC_03262 MAC_03508 MAC_03508 MAC_03514 MAC_03514 MAC_03830 MAC_03830 MAC_03845 MAC_03845 uba4 uba4 MAC_04108 MAC_04108 MAC_04116 MAC_04116 MAC_04174 MAC_04174 MAC_04274 MAC_04274 MAC_04295 MAC_04295 MAC_04404 MAC_04404 MAC_04551 MAC_04551 MAC_04626 MAC_04626 MAC_04795 MAC_04795 MAC_04866 MAC_04866 MAC_04904 MAC_04904 MAC_04937 MAC_04937 MAC_05017 MAC_05017 MAC_05018 MAC_05018 MAC_05025 MAC_05025 MAC_05099 MAC_05099 MAC_05252 MAC_05252 MAC_05256 MAC_05256 hxB hxB MAC_05308 MAC_05308 MAC_05328 MAC_05328 MAC_05545 MAC_05545 MAC_05547 MAC_05547 MAC_05584 MAC_05584 MAC_05588 MAC_05588 MAC_05591 MAC_05591 MAC_05686 MAC_05686 MAC_05889 MAC_05889 MAC_05893 MAC_05893 MAC_05903 MAC_05903 MAC_05906 MAC_05906 MAC_05917 MAC_05917 MAC_06003 MAC_06003 MAC_06145 MAC_06145 MAC_06149 MAC_06149 MAC_06382 MAC_06382 MAC_06420 MAC_06420 MAC_06743 MAC_06743 MAC_06951 MAC_06951 MAC_06957 MAC_06957 MAC_07001 MAC_07001 MAC_07129 MAC_07129 MAC_07133 MAC_07133 MAC_07274 MAC_07274 MAC_07275 MAC_07275 MAC_07368 MAC_07368 MAC_07388 MAC_07388 MAC_07540 MAC_07540 MAC_07658 MAC_07658 MAC_07740 MAC_07740 MAC_07771 MAC_07771 MAC_08099 MAC_08099 MAC_08100 MAC_08100 MAC_08101 MAC_08101 MAC_08148 MAC_08148 MAC_08207 MAC_08207 MAC_08219 MAC_08219 MAC_08372 MAC_08372 MAC_08410 MAC_08410 MAC_08479 MAC_08479 MAC_08506 MAC_08506 MAC_08536 MAC_08536 MAC_08580 MAC_08580 MAC_08670 MAC_08670 MAC_08860 MAC_08860 MAC_08897 MAC_08897 MAC_09037 MAC_09037 MAC_09039 MAC_09039 MAC_09183 MAC_09183 MAC_09288 MAC_09288 Pks2 Pks2 MAC_09389 MAC_09389 MAC_09497 MAC_09497 MAC_09549 MAC_09549 MAC_09673 MAC_09673 MAC_09707 MAC_09707 MAC_09708 MAC_09708 MAC_09711 MAC_09711 MAC_09762 MAC_09762 Pks1 Pks1 MAC_00143 MAC_00143 MAC_00144 MAC_00144 MAC_00177 MAC_00177 MAC_00440 MAC_00440 MAC_00485 MAC_00485 MAC_00513 MAC_00513 MAC_00700 MAC_00700 MAC_00893 MAC_00893 MAC_00950 MAC_00950 MAC_00979 MAC_00979 MAC_00982 MAC_00982 MAC_00791 MAC_00791 MAC_00799 MAC_00799 MAC_00833 MAC_00833 MAC_01099 MAC_01099 MAC_01111 MAC_01111 MAC_01115 MAC_01115 MAC_01212 MAC_01212 MAC_01214 MAC_01214 MAC_01215 MAC_01215 MAC_01216 MAC_01216 MAC_01240 MAC_01240 MAC_01293 MAC_01293 MAC_01352 MAC_01352 MAC_01356 MAC_01356 MAC_01502 MAC_01502 MAC_01519 MAC_01519 MAC_01522 MAC_01522 MAC_01406 MAC_01406 MAC_01445 MAC_01445 MAC_01787 MAC_01787 MAC_01801 MAC_01801 MAC_02046 MAC_02046 MAC_02054 MAC_02054 MAC_02214 MAC_02214 MAC_02298 MAC_02298 MAC_02301 MAC_02301 MAC_02362 MAC_02362 MAC_02370 MAC_02370 MAC_02500 MAC_02500 MAC_02665 MAC_02665 MAC_02764 MAC_02764 MAC_02845 MAC_02845 MAC_02861 MAC_02861 MAC_02872 MAC_02872 MAC_02889 MAC_02889
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAC_02898Polyketide synthase, putative. (556 aa)
MAC_03029Uncharacterized protein. (279 aa)
MAC_03039Uncharacterized protein. (696 aa)
MAC_03101Molybdenum cofactor biosynthesis protein 1 B. (677 aa)
MAC_03188Methylenetetrahydrofolate dehydrogenase. (339 aa)
MAC_03210Thiamine pyrophosphokinase. (333 aa)
MAC_03262Uncharacterized protein. (657 aa)
MAC_03508Putative cytochrome b5; Belongs to the cytochrome b5 family. (142 aa)
MAC_03514Riboflavin kinase. (351 aa)
MAC_03830Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (614 aa)
MAC_03845GST N-terminal domain-containing protein. (334 aa)
uba4Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (454 aa)
MAC_04108FAD synthetase, putative. (288 aa)
MAC_04116Polyketide synthase, putative. (1798 aa)
MAC_04174Uncharacterized protein. (124 aa)
MAC_04274Glutathione-S-transferase theta, GST, putative; Belongs to the GST superfamily. (277 aa)
MAC_042955'-nucleotidase; Belongs to the 5'-nucleotidase family. (657 aa)
MAC_04404Ser/Thr protein phosphatase. (604 aa)
MAC_04551Polyketide synthase, putative. (2627 aa)
MAC_04626Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (481 aa)
MAC_04795Biotin apo-protein ligase, putative. (670 aa)
MAC_04866Methylcrotonoyl-CoA carboxylase alpha chain. (673 aa)
MAC_04904Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (796 aa)
MAC_04937Dihydrofolate synthetase Fol3. (615 aa)
MAC_05017BTB domain-containing protein. (305 aa)
MAC_05018Dephospho-CoA kinase. (274 aa)
MAC_05025Calcineurin-like phosphoesterase, putative. (645 aa)
MAC_05099Thiamine pyrophosphokinase. (316 aa)
MAC_05252ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. (325 aa)
MAC_05256NAD kinase associated with ferric reductase. (607 aa)
hxBMolybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (777 aa)
MAC_05308MFS transporter, putative. (513 aa)
MAC_05328Mitochondrial thiamine pyrophosphate carrier 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (409 aa)
MAC_05545Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (464 aa)
MAC_05547Thioesterase family protein. (291 aa)
MAC_05584ATP-NAD kinase family protein. (480 aa)
MAC_055885'-nucleotidase; Belongs to the 5'-nucleotidase family. (599 aa)
MAC_05591Cytosolic hydroxymethyltransferase, putative. (336 aa)
MAC_05686Putative PKS-NRPS protein. (787 aa)
MAC_05889MFS transporter, putative. (273 aa)
MAC_05893Polyketide synthase, putative. (2555 aa)
MAC_05903Cysteine desulfurase. (482 aa)
MAC_05906PKS-like enzyme, putative. (164 aa)
MAC_05917Mitochondrial folate carrier protein Flx1, putative; Belongs to the mitochondrial carrier (TC 2.A.29) family. (312 aa)
MAC_06003Isoflavone reductase family protein. (322 aa)
MAC_06145Pyruvate carboxylase. (1240 aa)
MAC_06149Methenyltetrahydrofolate cyclohydrolase. (284 aa)
MAC_06382Pyridoxamine 5'-phosphate oxidase. (249 aa)
MAC_06420Tetracycline-efflux transporter, putative. (595 aa)
MAC_06743Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (549 aa)
MAC_06951Cytochrome p450, putative; Belongs to the cytochrome P450 family. (568 aa)
MAC_06957Hybrid PKS-NRPS protein. (262 aa)
MAC_07001DUF614 domain protein. (182 aa)
MAC_07129Glutathione S-transferase. (396 aa)
MAC_07133Uncharacterized protein. (401 aa)
MAC_07274Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (522 aa)
MAC_07275Folylpolyglutamate synthase. (422 aa)
MAC_07368Thiamine pyrophosphokinase, putative. (210 aa)
MAC_07388Uncharacterized protein. (374 aa)
MAC_07540Mitochondrial carrier protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (377 aa)
MAC_07658Putative lysosomal cobalamin transporter. (592 aa)
MAC_07740C-1-tetrahydrofolate synthase. (1063 aa)
MAC_07771Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (624 aa)
MAC_08099Fatty acid synthase S-acetyltransferase. (83 aa)
MAC_08100Fatty acid synthase S-acetyltransferase. (213 aa)
MAC_08101Polyketide synthase, putative. (159 aa)
MAC_08148Macro domain-containing protein. (217 aa)
MAC_08207Polyketide synthase. (2183 aa)
MAC_08219Phenolpthiocerol synthesis polyketide synthase ppsA. (2569 aa)
MAC_08372Polyketide synthase. (2378 aa)
MAC_08410Polyketide synthase, putative. (438 aa)
MAC_08479Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (321 aa)
MAC_08506DUF455 domain protein. (914 aa)
MAC_08536Thioesterase family protein. (338 aa)
MAC_08580FAD binding domain containing protein. (617 aa)
MAC_08670Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. (435 aa)
MAC_08860Amino acid adenylation domain protein. (1605 aa)
MAC_08897Thioesterase family protein. (284 aa)
MAC_09037Polyketide synthase. (382 aa)
MAC_09039Polyketide synthase, putative. (138 aa)
MAC_09183Dihydrofolate reductase. (234 aa)
MAC_09288Thiamin pyrophosphokinase-related protein. (242 aa)
Pks2Polyketide synthase 2; Polyketide synthase; part of the Pks2 gene cluster that mediates the formation of infectious structures (appressoria), enabling these fungi to kill insects faster (Probable). The product of the Pks2 gene cluster is different from the one of Pks1 and has still not been identified (Probable). (1861 aa)
MAC_09389Uncharacterized protein. (146 aa)
MAC_09497Polyketide synthase, putative. (2454 aa)
MAC_09549Polyketide synthase. (2488 aa)
MAC_09673Thioesterase family protein. (333 aa)
MAC_09707Carrier domain-containing protein. (1832 aa)
MAC_09708Citrinin biosynthesis oxydoreductase CtnB. (248 aa)
MAC_09711Polyketide synthase, putative. (2571 aa)
MAC_09762Uncharacterized protein. (133 aa)
Pks1Polyketide synthase 1; Polyketide synthase; part of the Pks1 gene cluster that mediates the biosynthesis of an anthraquinone derivative pigment that contributes to conidial pigmentation that provides protection from UV radiation, heat and cold stress. The polyketide synthase Pks1 produces 1-acetyl-2,4,6,8-tetrahydroxy-9,10-anthraquinone though condensation of acetyl-CoA with malonyl-CoA (By similarity). The dehydratase EthD and the laccase Mlac1 further convert the anthraquinone derivative into the final conidial pigment (By similarity). (2148 aa)
MAC_00143Polyketide synthase, putative. (203 aa)
MAC_00144Polyketide synthase, putative; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (139 aa)
MAC_00177Polyketide synthase. (2200 aa)
MAC_00440Acetyl-CoA carboxylase. (2285 aa)
MAC_00485Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (668 aa)
MAC_00513NAD kinase, putative. (594 aa)
MAC_00700MOSC domain containing protein. (340 aa)
MAC_00893Pantothenate kinase. (456 aa)
MAC_00950DFP domain-containing protein. (369 aa)
MAC_00979Fungal specific transcription factor, putative. (349 aa)
MAC_00982Uncharacterized protein; Belongs to the cytochrome P450 family. (501 aa)
MAC_00791Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (495 aa)
MAC_00799Mitochondrial carrier protein, putative; Belongs to the mitochondrial carrier (TC 2.A.29) family. (353 aa)
MAC_00833Methylcrotonoyl-CoA carboxylase beta chain. (569 aa)
MAC_01099Cysteine desulfurase. (499 aa)
MAC_01111Polyketide synthase. (3864 aa)
MAC_01115Beta-ketoacyl synthase. (358 aa)
MAC_01212Cytochrome P450, putative; Belongs to the cytochrome P450 family. (443 aa)
MAC_01214PKS-like enzyme, putative. (322 aa)
MAC_01215Polyketide synthase, putative. (2217 aa)
MAC_01216DUF341 domain protein. (204 aa)
MAC_01240Phosphotransferase enzyme family protein. (444 aa)
MAC_01293Mitochondrial carrier protein LEU5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (397 aa)
MAC_013525-formyltetrahydrofolate cyclo-ligase. (245 aa)
MAC_01356Molybdopterin binding domain protein. (244 aa)
MAC_01502Cytochrome P450; Belongs to the cytochrome P450 family. (565 aa)
MAC_01519Polyketide synthase, putative. (472 aa)
MAC_01522Polyketide synthetase PksP. (1925 aa)
MAC_01406Polyketide synthase, putative. (846 aa)
MAC_01445Flavokinase domain-containing protein. (684 aa)
MAC_01787Thiamin pyrophosphokinase-related protein. (322 aa)
MAC_01801Nicotinamide riboside kinase 1. (249 aa)
MAC_02046Meiotically up-regulated protein. (277 aa)
MAC_02054Dihydrofolate reductase. (263 aa)
MAC_02214Citrinin biosynthesis oxydoreductase CtnB. (237 aa)
MAC_02298Rhs family protein. (146 aa)
MAC_02301Uncharacterized protein. (290 aa)
MAC_02362Pantetheine-phosphate adenylyltransferase family protein. (444 aa)
MAC_02370Purine permease. (596 aa)
MAC_02500NADH pyrophosphatase. (429 aa)
MAC_02665Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family. (278 aa)
MAC_02764Polyketide synthase, putative. (246 aa)
MAC_02845MFS glucose transporter, putative; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (520 aa)
MAC_02861Flavoprotein, putative. (631 aa)
MAC_02872Polyketide synthase/peptide synthetase. (428 aa)
MAC_02889Biotin carboxylation domain-containing protein. (632 aa)
Your Current Organism:
Metarhizium acridum
NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102
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