(11 nodes) Downstream TCR signaling network (Metarhizium acridum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_09532	F-box and WD40 domain protein, putative. (693 aa)
	MAC_09841	Complex I intermediate-associated protein 30. (227 aa)
	MAC_08750	Putative 3-phosphoinositide dependent protein kinase-1 (PDK1). (1212 aa)
	MAC_08284	BZIP domain-containing protein. (257 aa)
	MAC_06069	Uncharacterized protein. (147 aa)
	MAC_05764	TRAF-type zinc finger protein. (555 aa)
	MAC_03999	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1142 aa)
	MAC_02642	Ubiquitin. (343 aa)
	MAC_02558	Uncharacterized protein. (388 aa)
	MAC_01946	Ubiquitin. (153 aa)
	MAC_01706	F-box/WD-40 repeat-containing protein. (1008 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_01706	MAC_01946	E9DVQ8	E9DWE8	F-box/WD-40 repeat-containing protein.	Ubiquitin.	0.448
MAC_01706	MAC_02642	E9DVQ8	E9DYE5	F-box/WD-40 repeat-containing protein.	Ubiquitin.	0.607
MAC_01706	MAC_08284	E9DVQ8	E9EEI6	F-box/WD-40 repeat-containing protein.	BZIP domain-containing protein.	0.448
MAC_01706	MAC_09841	E9DVQ8	E9EIZ3	F-box/WD-40 repeat-containing protein.	Complex I intermediate-associated protein 30.	0.448
MAC_01946	MAC_01706	E9DWE8	E9DVQ8	Ubiquitin.	F-box/WD-40 repeat-containing protein.	0.448
MAC_01946	MAC_02642	E9DWE8	E9DYE5	Ubiquitin.	Ubiquitin.	0.984
MAC_01946	MAC_05764	E9DWE8	E9E7B6	Ubiquitin.	TRAF-type zinc finger protein.	0.874
MAC_01946	MAC_09532	E9DWE8	E9EI34	Ubiquitin.	F-box and WD40 domain protein, putative.	0.448
MAC_02558	MAC_03999	E9DY60	E9E2A1	Uncharacterized protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.812
MAC_02642	MAC_01706	E9DYE5	E9DVQ8	Ubiquitin.	F-box/WD-40 repeat-containing protein.	0.607
MAC_02642	MAC_01946	E9DYE5	E9DWE8	Ubiquitin.	Ubiquitin.	0.984
MAC_02642	MAC_05764	E9DYE5	E9E7B6	Ubiquitin.	TRAF-type zinc finger protein.	0.955
MAC_02642	MAC_08284	E9DYE5	E9EEI6	Ubiquitin.	BZIP domain-containing protein.	0.846
MAC_02642	MAC_09532	E9DYE5	E9EI34	Ubiquitin.	F-box and WD40 domain protein, putative.	0.607
MAC_02642	MAC_09841	E9DYE5	E9EIZ3	Ubiquitin.	Complex I intermediate-associated protein 30.	0.846
MAC_03999	MAC_02558	E9E2A1	E9DY60	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Uncharacterized protein.	0.812
MAC_03999	MAC_05764	E9E2A1	E9E7B6	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	TRAF-type zinc finger protein.	0.680
MAC_03999	MAC_06069	E9E2A1	E9E871	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Uncharacterized protein.	0.812
MAC_03999	MAC_08750	E9E2A1	E9EFV2	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Putative 3-phosphoinositide dependent protein kinase-1 (PDK1).	0.988
MAC_05764	MAC_01946	E9E7B6	E9DWE8	TRAF-type zinc finger protein.	Ubiquitin.	0.874