(17 nodes) Mitophagy network (Metarhizium acridum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_04744	Fungal specific transcription factor, putative. (696 aa)
	MAC_05227	Mitochondrial import receptor subunit TOM40. (377 aa)
	MAC_06410	Mitochondrial import receptor subunit tom-20. (196 aa)
	MAC_07123	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (256 aa)
	MAC_07285	Casein kinase II, alpha chain (CK II alpha subunit); Belongs to the protein kinase superfamily. (427 aa)
	MAC_08034	GTPase FZO1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (744 aa)
	MAC_08764	Autophagy-related protein. (108 aa)
	MAC_01160	Mitochondrial outer membrane 72kDa protein. (622 aa)
	MAC_01647	Mitochondrial import receptor subunit tom-22. (153 aa)
	MAC_02642	Ubiquitin. (343 aa)
	MAC_02739	Autophagy-related ubiquitin-like modifier atg-12. (121 aa)
	MAC_03681	GTPase FZO1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (895 aa)
	MDM34	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (552 aa)
	MAC_03903	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (254 aa)
	MAC_03904	Cell surface protein, putative. (467 aa)
	MAC_04729	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (343 aa)
	MAC_04998	Serine/threonine-protein kinase. (948 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_01160	MAC_01647	E9DU62	E9DVJ9	Mitochondrial outer membrane 72kDa protein.	Mitochondrial import receptor subunit tom-22.	0.980
MAC_01160	MAC_03681	E9DU62	E9E1D3	Mitochondrial outer membrane 72kDa protein.	GTPase FZO1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.404
MAC_01160	MAC_05227	E9DU62	E9E5S9	Mitochondrial outer membrane 72kDa protein.	Mitochondrial import receptor subunit TOM40.	0.978
MAC_01160	MAC_06410	E9DU62	E9E962	Mitochondrial outer membrane 72kDa protein.	Mitochondrial import receptor subunit tom-20.	0.994
MAC_01160	MAC_08034	E9DU62	E9EDT6	Mitochondrial outer membrane 72kDa protein.	GTPase FZO1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.404
MAC_01647	MAC_01160	E9DVJ9	E9DU62	Mitochondrial import receptor subunit tom-22.	Mitochondrial outer membrane 72kDa protein.	0.980
MAC_01647	MAC_05227	E9DVJ9	E9E5S9	Mitochondrial import receptor subunit tom-22.	Mitochondrial import receptor subunit TOM40.	0.999
MAC_01647	MAC_06410	E9DVJ9	E9E962	Mitochondrial import receptor subunit tom-22.	Mitochondrial import receptor subunit tom-20.	0.992
MAC_02642	MAC_03681	E9DYE5	E9E1D3	Ubiquitin.	GTPase FZO1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.610
MAC_02642	MAC_08034	E9DYE5	E9EDT6	Ubiquitin.	GTPase FZO1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.610
MAC_02642	MAC_08764	E9DYE5	E9EFW6	Ubiquitin.	Autophagy-related protein.	0.520
MAC_02739	MAC_03681	E9DYP2	E9E1D3	Autophagy-related ubiquitin-like modifier atg-12.	GTPase FZO1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.668
MAC_02739	MAC_03903	E9DYP2	E9E1T5	Autophagy-related ubiquitin-like modifier atg-12.	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	0.999
MAC_02739	MAC_03904	E9DYP2	E9E1T6	Autophagy-related ubiquitin-like modifier atg-12.	Cell surface protein, putative.	0.955
MAC_02739	MAC_04998	E9DYP2	E9E5C2	Autophagy-related ubiquitin-like modifier atg-12.	Serine/threonine-protein kinase.	0.983
MAC_02739	MAC_08034	E9DYP2	E9EDT6	Autophagy-related ubiquitin-like modifier atg-12.	GTPase FZO1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.668
MAC_02739	MAC_08764	E9DYP2	E9EFW6	Autophagy-related ubiquitin-like modifier atg-12.	Autophagy-related protein.	0.944
MAC_03681	MAC_01160	E9E1D3	E9DU62	GTPase FZO1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Mitochondrial outer membrane 72kDa protein.	0.404
MAC_03681	MAC_02642	E9E1D3	E9DYE5	GTPase FZO1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Ubiquitin.	0.610
MAC_03681	MAC_02739	E9E1D3	E9DYP2	GTPase FZO1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Autophagy-related ubiquitin-like modifier atg-12.	0.668